The Therapeutic Effects of Acorus Tatarinowii Volatile Oil and Electroacupuncture in Post‐Stroke Cognitive Impairment Patients: A Clinical Trial Protocol by Ying Dandan, Zhao Jingting, Wang Minzhe, Cai Zhuoyue, Li Xinyun

“…Data analysis will be conducted using a modified intention‐to‐treat approach. …”
Get full text

Transcript PHF19-207 May Be a Long Non-Coding RNA with Tumor-Promoting Role in Colon Cancer by Dunja Pavlovic, Tamara Babic, Sofija Ignjatovic, Katarina Pavlovic, Sandra Dragicevic, Aleksandra Nikolic

“…The objective of this study was to investigate the function of PHF19-207 using in silico tools and publicly available data, as well as to assess its expression in colon cancer. …”
Get full text

Energy Calibration and Inverse-Square Law of Radiation in Gamma-Ray Measurement Using a Scintillation Detector for Laboratory Experiments by Shiori Iida, Wei-Guo Jin

“…Results revealed that employing quadratic or cubic function fits for energy calibration yielded more than twice the accuracy compared to the conventional linear function fit. …”
Get full text

Non-linear mixed-effects modelling and population-based model selection for 131I kinetics in benign thyroid disease by Deni Hardiansyah, Ade Riana, Heribert Hänscheid, Ambros J. Beer, Michael Lassmann, Gerhard Glatting

“…Akaike weight was used to identify the performance of the best model from PBMS-NLME and the EANM SOP SOE function with individual fitting. Results Based on the PBMS-NLME analysis, the SOEF $$\frac{{\lambda_{1} }}{{\lambda_{2} + \lambda_{1} - \lambda_{3} }}\left( {e^{{ - \left( {\lambda_{3} + \lambda_{phys} } \right)t}} - e^{{ - \left( {\lambda_{1} + \lambda_{2} + \lambda_{phys} } \right)t}} } \right) + a_{1} e^{{ - \left( {\lambda_{1} + \lambda_{2} + \lambda_{phys} } \right)t}}$$ λ 1 λ 2 + λ 1 - λ 3 e - λ 3 + λ phys t - e - λ 1 + λ 2 + λ phys t + a 1 e - λ 1 + λ 2 + λ phys t was selected as the function most supported by the data. …”
Get full text

The Predictors of Dietary Supplement Use Among Women With Musculoskeletal Disease: A Population-Based Complex Sample Designed Study by Myoungjin Kwon PhD, Sun Ae Kim PhD, Youngshin Song PhD

“…A cross-sectional study and secondary data analysis were designed using a representative, multilevel stratified cluster sample from the 8th wave (2019) of the National Health and Nutrition Examination Survey, a national statistical survey encompassing health status, health behaviors, and food and nutrient consumption. …”
Get full text

Optimization the preparation of whey protein from pasteurized liquid milk using Response Surface Methodology and Artificial Neural Network Model by Md. Anwar Hossain, Kanika Mitra, Md. Munnaf Hossen, Shammi Akhter

“…The regression model's suitability was confirmed by the well-fitted analysis data. The present study showed that WPC could produce bio-functional hydrolysates with antioxidant and amino acid activity. …”
Get full text

Distribution and diversity of classical deacylases in bacteria by Leonie G. Graf, Carlos Moreno-Yruela, Chuan Qin, Sabrina Schulze, Gottfried J. Palm, Ole Schmöker, Nancy Wang, Dianna M. Hocking, Leila Jebeli, Britta Girbardt, Leona Berndt, Babett Dörre, Daniel M. Weis, Markus Janetzky, Dirk Albrecht, Daniela Zühlke, Susanne Sievers, Richard A. Strugnell, Christian A. Olsen, Kay Hofmann, Michael Lammers

“…Thus, we provide a systematic structure-function analysis of classical deacylases in bacteria and reveal the basis of substrate specificity, acyl-chain preference and inhibition.…”
Get full text

PAQR6 as a prognostic biomarker and potential therapeutic target in kidney renal clear cell carcinoma by Tao Zou, Zongming Jia, Jixiang Wu, Xuxu Liu, Minghao Deng, Xuefeng Zhang, Yuxin Lin, Yuxin Lin, Jigen Ping

“…However, its biological function in kidney renal clear cell carcinoma (KIRC) and its potential as a therapeutic target remain underexplored.MethodsIn this study, PAQR6 was identified as a critical oncogene by WGCNA algorithm and differential gene expression analysis using TCGA - KIRC and GSE15641 data. …”
Get full text

Identification of potential pathogenic genes associated with the comorbidity of rheumatoid arthritis and renal fibrosis using bioinformatics and machine learning by Jiao Qiu, Yalin Xu, Luyuan Tong, Xingchun Yang, Xiao Wu

“…Subsequently, functional enrichment analysis was performed to clarify the biological functions of these genes. …”
Get full text

Methotrexate in the treatment of rheumatoid arthritis and psoriatic arthritis by N. V. Chichasova, A. M. Lila

“…The advantages of the subcutaneous form of methotrexate in terms of efficacy and tolerability for both rheumatoid and psoriatic arthritis are discussed. Data on the tolerance of the subcutaneous form of methotrexate from various manufacturers are presented.Analysis of literature data and the results of our own research indicate the need for early prescription of methotrexate in patients with rheumatoid arthritis and patients with peripheral joint lesions in psoriatic arthritis.Numerous studies confirm the effectiveness of methotrexate in rheumatoid arthritis in relation to the symptoms of the disease, both articular and non-articular, structural damage (slowing down X-ray progression), which is accompanied by an improvement in the patient’s functional abilities. …”
Get full text

Surgery/anesthesia may cause monocytes to promote tumor development by Yang-Yang Wang, Rui-Lou Zhu, En-Qiang Chang, Xiao-Zhuan Liu, Guang-Zhi Wang, Ning-Tao Li, Wei Zhang, Jun Zhou, Ming-Yang Sun, Xin Zou, Jie Hao, Jia-Qiang Zhang

“…Methods We performed an in-depth analysis of our previously published data, which included a total of 4 patients were recruited in this study. …”
Get full text

Hsa_circ_0007991 Promotes Immune Evasion in Hepatocellular Carcinoma via Regulation of the miR-505-3p/CANX Axis by Wang L, Liang L, Qian J, Yu C, Shi Y, Yan X, Chen X

“…LingLing Wang,1,* Li Liang,2,* Jing Qian,3 Chao Yu,1 Yu Shi,3 XiaoDi Yan,3 Xiang Chen1 1Department of Clinical Laboratory, Nantong First People’s Hospital, Nantong City, Jiangsu Province, 226000, People’s Republic of China; 2Department of Interventional, Nantong First People’s Hospital, Nantong City, Jiangsu Province, 226000, People’s Republic of China; 3Department of Tumor Radiotherapy, Affiliated Hospital of Nantong University, Nantong City, Jiangsu Province, 226001, People’s Republic of China*These authors contributed equally to this workCorrespondence: Xiang Chen, Department of Inspection, Nantong First People’s Hospital, No. 666, Shengli Road, Guanyinshan Street, Chongchuan District, Nantong City, Jiangsu Province, 226000, People’s Republic of China, Email chenxiang_CXCH@hotmail.comObjective: This study aimed to investigate the expression and functional role of hsa_circ_0007991 in hepatocellular carcinoma (HCC).Methods: RNA expression data of HCC and corresponding non-tumor liver tissues were obtained from the GEO database, and differential expression analysis was conducted to identify significantly dysregulated circRNAs. …”
Get full text

THE INDICES DYNAMICS OF PLATELET POOL AND THE LEVEL OF TGF-Β₁ IN DIFFERENT FORMS OF ACUTE PANCREATITIS by E. N. Smolina, O. V. Pridantseva, M. B. Kadinskaya, O. V. Galkina, E. O. Bogdanova

“…The data obtained showed that the changes of indices of quantitative and functional characteristics of platelets are the important pathogenetic criterion of prognosis for severity of clinical course of acute pancreatitis.…”
Get full text

On the Zhang-power series distributions with application to lifetime modeling by Hamideh Memarbashi, Javad Etminan, Majid Chahkandi

“…This distribution is very useful in the lifetime, reliability and extreme-value data analysis. The distribution properties including survival function, hazard function and limiting behavior of the probability density  and hazard functions are studied. …”
Get full text

The Arctan-X Family of Distributions: Properties, Simulation, and Applications to Actuarial Sciences by Ibrahim Alkhairy, M. Nagy, Abdisalam Hassan Muse, Eslam Hussam

“…The purpose of this paper is to investigate a new family of distributions based on an inverse trigonometric function known as the arctangent function. In the context of actuarial science, heavy-tailed probability distributions are immensely beneficial and play an important role in modelling data sets. …”
Get full text

Berberine Mediates Exosomes Regulating the Lipid Metabolism Pathways to Promote Apoptosis of RA-FLS Cells by Si-Fan Guo, Zhi-Bo Wang, Dan-Dan Xie, Ying Cai, Yan Wang, Xian Wang, Qiang Yang, Ai-Hua Zhang, Shi Qiu

Get full text

Hyperuricemia suppresses lumican, exacerbating adverse remodeling after myocardial infarction by promoting fibroblast phenotype transition by Zehao Zhuang, Ao Liu, Jinghong Zhang, Shuangjian Han, Lu Tang, Tingting Yu, Yiping Shi, Hui Li, Heng Yang, Peiyuan Bai, Yanhua Tang

“…We conducted an enzyme-linked immunosorbent assay, histological detection, immunofluorescence, sequencing data processing, single-cell RNA-seq, and functional enrichment analysis. …”
Get full text

DeSPPNet: A Multiscale Deep Learning Model for Cardiac Segmentation by Elizar Elizar, Rusdha Muharar, Mohd Asyraf Zulkifley

“…Cardiac MRI allows medical practitioners to assess cardiac function accurately by providing comprehensive and quantitative information about the structure and function, hence making it an indispensable tool for monitoring the disease and treatment response. …”
Get full text

Astrocytic lipid droplets contain MHCII and may act as cogs in the antigen presentation machinery by Chiara Beretta, Abdulkhalek Dakhel, Khalid Eltom, Fredrik Rosqvist, Simon Uzoni, Tobias Mothes, John S. Fletcher, Ulf Risérus, Dag Sehlin, Jinar Rostami, Wojciech Piotr Michno, Anna Erlandsson

“…Here, we describe a novel function of LDs in human astrocytes, in the context of Alzheimer’s disease (AD). …”
Get full text

Study on Heat Dissipation of Reduction Gearbox of a Hoisting Mechanism in Stopped State by Gao Chunhui, Hu Xiong

“…In order to verify the actual influence of these factors on the reducer heat dissipation,by using the control variable method,the actual temperature data is computed and analyzed. Then,by means of the function mapping software Origin,the temperature data of the reduction gearbox is fitted,a quadratic exponential function model is fitted and the function parameter is obtained. …”
Get full text