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9741
Efficiency of L-arginine and L-carnitine in the Complex Treatment of Patients With Acute Myocardial Infarction and Comorbid Metabolic Syndrome
Published 2018-12-01“…Results and discussion. The comparative analysis of the structural and functional parameters of the heart, according to echocardiographic data of 34 patients with MI who received standard protocol treatment with the corresponding parameters in 48 patients who had received additional treatment including L-arginine and L-carnitine, showed that the size of the left atrium was significantly lower in the examined test group (p = 0.02), and slight decrease of the aorta size, the thickness of the interventricular septum, the diastolic size of the left and right ventricles, which led to the significant increase of left ventricle ejection fraction by 9,1 % (p = 0.01). …”
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9742
Interface Alterations in Cellulose Synthases Redefine CESA Complex Assembly to Enhance Cellulosic Biomass Production
Published 2025-07-01“…This study integrates evolutionary analysis, structural modeling, and functional data to elucidate the sequence‐structure–function relationships of CESAs. …”
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9743
A comparison of human skeletal muscle cell maturation in 2D versus 3D culture: A quantitative proteomic study
Published 2025-06-01“…Quantitative proteomic analysis and functional measurements were conducted to evaluate muscle cell differentiation. …”
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9744
An iASPP‐derived short peptide restores p53‐mediated cell death in cancers with wild‐type p53
Published 2023-09-01“…Functional analysis suggested that A8 restored the transcriptional function and DNA binding activities of p53 toward the Bax and PUMA gene promoters. …”
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9745
Integrated meta‐QTL and in silico transcriptome assessment pinpoint major genomic regions responsible for spike length in wheat (Triticum aestivum L.)
Published 2024-09-01“…Integration of MQTL analysis and in silico transcriptome data led to a significant increase in the reliability of CGs for the genetic regulation of wheat SL, and the haplotype analysis for key CGs TaPP2C‐3B of SL provided insights into the biological function of the TaPP2C‐3B gene.…”
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9746
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9747
Dendritic cell-derived MYD88 potentiates as a biomarker for immune regulation in hepatocellular carcinoma and may predict a better immunological result
Published 2025-03-01“…Furthermore, immunohistochemical (IHC) staining was performed to reassess the biological effects of MyD88 in HCC patients undergoing immune checkpoint inhibitor (ICI) therapy.ResultsOur pan-cancer data analysis further highlights the significant impact of MYD88 on clinical outcomes in HCC. …”
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9748
Chapter 8: Biological knowledge assembly and interpretation.
Published 2012-01-01“…Biomedical ontology and pathway-based functional enrichment analysis is widely used to interpret the functional role of tightly correlated or differentially expressed genes. …”
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9749
MULTIMODAL APPROACH TO THE STUDY OF SPECIALIZED TEXTS IN TECHNICAL DISCOURSE
Published 2023-12-01“…The principles of the multimodal approach and a model for conducting a multimodal analysis of a text are considered. As mentioned in the article, the multimodal approach can be applied to analyzing all types and forms of communication, including the analysis of texts, including technical ones, in which two or more semiotic resources are integrated and interact to realize the communicative functions of the text. …”
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9750
The organization of the transcriptional network in specific neuronal classes
Published 2009-07-01“…Here, we perform the first systems‐level analysis of microarray data from single neuronal populations using weighted gene co‐expression network analysis to examine how neuronal transcriptome organization relates to neuronal function and diversity. …”
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9751
Unique intrahepatic transcriptomics profiles discriminate the clinical phases of a chronic HBV infection.
Published 2017-01-01“…Therefore, we determined, for the first time, intrahepatic global expression profiles of well-characterized chronic HBV patients at different clinical phases. Our data, obtained by microarray, demonstrate that B cells and NK/cytotoxic-related genes in the liver, including CD19, TNFRSF13C, GZMH, and KIR2DS3, were differentially expressed across the clinical HBV phases, which was confirmed by modular analysis and also Nanostring arrays in an independent cohort. …”
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9752
Characteristics of gut microbiota in people with circadian rhythm disruption and its correlation with cognition
Published 2025-05-01“…Metagenomics, Alpha and Beta diversity analyses, Linear Discriminant Analysis Effect Size (LEfSe), and Kyoto Encyclopedia of Genes and Genomes (KEGG) analysis were employed to investigate the diversity and function characteristics of gut microbiota in the participants. …”
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9753
Promising methods of prenatal diagnostics based on passive sensors and machine learning
Published 2025-03-01“…The conducted literature analysis allowed to generalize the experimental achievements of current methods of prenatal diagnostics and demonstrated great promise for automated systems to assess fetal vital signs, including monitoring fetal HR, motor activity and general functional state. …”
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9754
Comparative characteristics of vegetative support of central hemodynamics and physical performance of runners on 400 meters of both genders
Published 2016-03-01“…Scientific search in the direction of the analysis of the mechanisms of adaptive reorganizations in the female body under the influence of sports and diagnostics of functional state is essential and urgent problem, which is of great importance in sports medicine. …”
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9755
Comparative assessment of a virtual performance measure with self-report and performance-based outcomes in patients with hip osteoarthritis
Published 2025-01-01“…Methods The VPM score was based on the results of 10 videos showing increasing difficulty in performing specific functional tasks. Patients were requested to choose the video that best reflected their own level of function. …”
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9756
Genome-wide association study to identify biological and metabolic pathways associated with carcass portion weights in turkeys
Published 2025-07-01“…The objective of this study was to conduct a genome wide association study (GWAS) and functional analysis on turkey carcass portion weights. …”
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9757
Deep proteome profiling of metabolic dysfunction-associated steatotic liver disease
Published 2025-03-01“…Conclusions Our comprehensive proteomic analysis deepens the understanding of liver function and MASLD pathology by elucidating key cellular mechanisms and multi-organ interactions, and demonstrates the robustness of a proteomics-based biomarker panel to enhance diagnosis of MASLD and significant fibrosis.…”
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9758
Systematic Construction and Validation of a Novel Ferroptosis-Related Gene Model for Predicting Prognosis in Cervical Cancer
Published 2022-01-01“…Ferroptosis-related differential genes in cervical cancer were detected using the “limma” R function and WGCNA. The least absolute shrinkage and selection operator (LASSO) algorithm and Cox regression analysis were conducted to develop a novel prognostic signature. …”
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9759
Conceptualization of Temporal Relationships Structuring the Emotional World of a Person in the Poem “No – leave my heart to rest” by T. Moore
Published 2022-12-01“…In the process of analyzing lexical material in the article, the following research methods were used: the method of continuous sampling, the functional-semantic method, the method of component analysis, the method of definitional analysis, as well as the descriptive method and the method of quantitative data processing.Results and discussion. …”
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9760
Assessment of the effectiveness of PAH-specific therapy, including selexipag, in patients with idiopathic pulmonary hypertension according to a comprehensive examination using Rama...
Published 2023-11-01“…Aim: to assess the effectiveness of PAH-specific therapy, including selexipag, based on data from a comprehensive examination and assessment of oxygen transport function in patients with IPAH using Raman spectroscopy.Materials and methods. …”
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