A cross-tissue transcriptome-wide association study identifies WDPCP as a potential susceptibility gene for coronary atherosclerosis by Xinyue Hu, Guanglei Chen, Xiaofang Yang, Jin Cui, Ning Zhang

“…While genome-wide association studies (GWAS) have pinpointed many risk loci, over 75 % are in non-coding regions, complicating functional analysis and understanding gene-disease mechanisms. …”
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A cross-tissue transcriptome-wide association study reveals GRK4 as a novel susceptibility gene for COPD by Guanglei Chen, Yaxian Jin, Cancan Chu, Yuhao Zheng, Changfu Yang, Yunzhi Chen, Xing Zhu

“…Subsequently, candidate susceptibility genes were screened using Multi-marker Analysis of Genomic Annotation (MAGMA). The causal relationship between these candidate genes and COPD was further evaluated through summary data-based Mendelian randomization (SMR), colocalization analysis, and Mendelian randomization (MR). …”
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Retroelement co-option disrupts the cancer transcriptional programme by Jane Loong, Rachael Thompson, Callum Hall, Laura Doglio, Judith Pape, Tobias Plowman, George Kassiotis

“…These were subsequently verified in test cases by further analysis of transcriptional profiles in cancer patient data, and by in vitro studies involving restoration of gene activity, and proliferation and migration assays in cancer cell lines. …”
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Genome-wide divergence of DNA methylation marks in cerebral and cerebellar cortices. by Yurong Xin, Benjamin Chanrion, Meng-Min Liu, Hanga Galfalvy, Ramiro Costa, Boro Ilievski, Gorazd Rosoklija, Victoria Arango, Andrew J Dwork, J John Mann, Benjamin Tycko, Fatemeh Haghighi

“…Such differences were observed in distinct genomic regions, including genes involved in CNS function. The MSNP data were validated for a subset of these genes, by performing bisulfite cloning and sequencing and confirming that prefrontal, occipital, and temporal cortices are significantly more methylated as compared to the cerebellum.…”
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Syntactic Representation of predicational copular clauses in Persian Language by Maryam Khamse Ashari, Rezvan Motavallian

“…The Functional Category Hypothesis (FCH), also known as the asymmetric small clause analysis, was first introduced by Bowers (1993, 2001) and further supported by Bailyn (2001), Bailyn and Citko (1999), Baker (2008), Mikkelsen (2005), Hedberg & Potter (2010). …”
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BENTUK, FUNGSI, DAN MAKNA LELAKAQ SASAK SEBAGAI MEDIA KAMPANYE CALON WALIKOTA MATARAM by Usman Jayadi

“…The method of collecting data in this research are observation, quotation, document and in analysis data use structural analysis and Semiotic for type analysis. …”
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Targeted Biofeedback Training to Improve Gait Parameters in Subacute Stroke Patients: A Single-Blind Randomized Controlled Trial by Dmitry V. Skvortsov, Sergey N. Kaurkin, Galina E. Ivanova

“…Assessments based on clinical scales and gait analysis data (spatiotemporal, kinematic, and EMG parameters) were performed before and after the training course. …”
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Application of mechanical quantitative techniques in postoperative rehabilitation assessment of anterior cruciate ligament reconstruction: A study protocol. by Zhichun Zhu, Jianyun Zhang, Wenxiang Ouyang, Tiantian Li, Jinsong Xiong, Mi Fan, Jing Guo, Peng Wang, Yongqing Tong, Yulu Yao

“…Traditional assessment methods are limited by subjectivity and the absence of quantitative data. Mechanical quantitative techniques present a novel approach, offering objective and precise quantitative metrics for knee functional rehabilitation through the analysis of soft tissue mechanical properties.…”
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Faktor-Faktor yang Memengaruhi Niat Terus Menggunakan Platform Akuakultur Elektronis: Studi Kasus Aplikasi eFisheryku by Andre Nurrohman, Imairi Eitiveni

“…The research method used is an explanatory sequential design, which is a research method that begins with a quantitative phase and continues to follow up certain results with a qualitative phase to help explain integrated quantitative results. Quantitative data analysis was carried out on 100 questionnaire data using the PLS-SEM analysis technique. …”
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Molecular insights into the bidirectional link between anxiety and COVID-19: a combined clinical and bioinformatics approach by Wenjie Huang, Biao Hu, Chengyu Gu, Hao Wu, Yize Huang, Dexiang Yang

“…In parallel, we conducted a comprehensive literature-based data mining analysis to reconstruct the functional and molecular pathways linking COVID-19 and anxiety. …”
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Therapeutic role of mesenchymal stem cells in neurogenesis for management of neurological disorders: a scientometric study to an in-depth review by Qian Wang, Weifeng Jiang, Yan Feng, Lin Li, Lisheng Chu, Yan Fang

“…BackgroundThe biological process of neurogenesis involves the production of new and completely functional neurons in two specific regions of the brain: the ventricular-subventricular zone (V-SVZ) and the subgranular zone (SGZ) of the hippocampal dentate gyrus by neural stem cells (NSCs). …”
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Genome-wide identification of SIMILAR to RCD ONE (SRO) gene family in rapeseed (Brassica napus L.) reveals their role in drought stress response by Huanhuan Jiang, Yuling Zhang, Jia Li, Rongzi Tang, Fenghao Liang, Rong Tang, Yuyu Zhou, Chao Zhang

“…Transcriptome data analysis and qPCR detection indicated that BnaSROs exhibit multiple stress-responsive expression patterns. …”
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Active poly‐GA vaccination prevents microglia activation and motor deficits in a C9orf72 mouse model by Qihui Zhou, Nikola Mareljic, Meike Michaelsen, Samira Parhizkar, Steffanie Heindl, Brigitte Nuscher, Daniel Farny, Mareike Czuppa, Carina Schludi, Alexander Graf, Stefan Krebs, Helmut Blum, Regina Feederle, Stefan Roth, Christian Haass, Thomas Arzberger, Arthur Liesz, Dieter Edbauer

“…Ovalbumin‐(GA)10 immunization largely rescued the motor function in (GA)149‐CFP transgenic mice and reduced poly‐GA inclusions. …”
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Genome-wide identification of long non-coding RNAs reveals potential association with Phytophthora infestans asexual and sexual development by Weilin Cao, Xiangming Pan, Ru Yu, Yuting Sheng, Hongxia Zhang

“…Our study conducted a comprehensive analysis of lncRNAs in P. infestans and suggested a potential function of lncRNAs in asexual and sexual development.IMPORTANCEThis study systematically analyzed lncRNAs in Phytophthora infestans, revealing the associations between lncRNAs and functional genes. …”
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Patient-centered outcomes on preparing for and undergoing gender-affirming phalloplasty: a qualitative, descriptive study by Daphna Harel, Asa Radix, Rachel Bluebond-Langner, Tenny R Zhang, Carolyn A Berry, Nnenaya Mmonu, Elijah Castle, Lee Zhao, Clarissa Ospina-Norvell, Mark Fendrick

“…Discussions were guided by participant input and focused on goals, experiences, outcomes, satisfaction, and quality of life.Setting This volunteer but purposive sample of patients was recruited directly in clinic, via email, and via social media at NYU Langone Health (primary site), Callen-Lorde Community Health Center (New York, New York, USA) and the San Francisco Community Health Center.Participants We conducted focus groups with 18 patients before/after undergoing gender-affirming phalloplasty/metoidioplasty.Primary and secondary outcome measurements and statistical analysis Transcripts were uploaded into ATLAS.ti, a qualitative data analysis software that facilitates coding for thematic content analysis. …”
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Quantitative evaluation and obstacle factor diagnosis of drug regulatory capacity in China. by Mingming Zhai, Liwen Huang, Shijie Sun, Liying Cao, Xueqiong Yue, Yuanxia Hu

“…<h4>Methods</h4>Using the methods of literature research, expert interviews, investigation and analysis, the quantitative evaluation indicator system of supervision ability was established in all directions; the indicator data were collected and quantified; the indicator weight setting algorithm of the evaluation system was improved and the indicator weight was set by combining AHP and entropy method; the differences among eastern, central, and western provincial-level regions were analyzed by variance analysis; panel data were constructed for spatio-temporal evolution analysis; obstacle factor diagnosis model was used to analyze the obstacle factors.…”
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High-throughput sequencing unravels placental vascular dysfunction and oxidative stress as mechanistic drivers of advanced maternal age-associated pregnancy by Xin Sun, Yao Chen, Feifei Hu, Yumeng Qiao, He Wu, Yao Su, Yue Hu, Jie Wu, Jie Wu, Mingli Huang

“…Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) enrichment analyses were performed to identify functional pathways of dysregulated genes. Weighted gene co-expression network analysis (WGCNA) was utilized to detect AMA-related modules and hub genes, which were subsequently validated via Western blotting, qPCR, and immunohistochemistry (IHC).ResultsAnalysis of placental pathology (n = 129) identified advanced maternal age (AMA) as an independent risk factor for maternal vascular malperfusion (MVM) (OR = 3.022, 95% CI 1.337–6.832). …”
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PERAMALAN PERGERAKAN LALU LINTAS UDARA DI BANDARA INTERNASIONAL I GUSTI NGURAH RAI MENGGUNAKAN ANALISIS INTERVENSI by INDAH LARASATI WIRYANINGRUM, I WAYAN SUMARJAYA, KARTIKA SARI

“…In this study, the pulse function intervention analysis was used to examine data on the number of aircraft at I Gusti Ngurah Rai International Airport, both domestic and international flights in the period January 2013 to July 2020. …”
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Optimal frequency of platelet-rich plasma injections for managing osteoarthritis: A longitudinal study by Masahiko Kemmochi

“…To determine whether PRP can induce sustained structural improvements, we used the MRI Osteoarthritis Knee Score (MOAKS) to monitor changes in bone-marrow lesions (BMLs). Data were analyzed using repeated-measures analysis of variance to identify significant changes in pain and functional outcomes. …”
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The Effect of Cantilevers on Interior Lighting: Case of Denizli Merkezefendi Library by Akif Ayberk Çetin, Şule Yılmaz Erten

“…Dialux program was used for data analysis and lighting simulation of the building. …”
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