Characterizing trajectories of diabetes-related health parameters before diabetes diagnosis in diabetes subtypes: analysis of a 20-year long prospective cohort study in Sweden by Tatjana P. Liedtke, Eike A. Strathmann, Emma Ahlqvist, Olof Asplund, Charlena S. Penz, Paula Stürmer, Cara Övermöhle, Anton Lager, Boel Brynedal, Hrafnhildur Gudjonsdottir, Wolfgang Lieb, Katharina S. Weber

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Subtype cluster analysis unveiled the correlation between m6A- and cuproptosis-related lncRNAs and the prognosis, immune microenvironment, and treatment sensitivity of esophageal c... by Ming Zhang, Yani Su, Pengfei Wen, Xiaolong Shao, Peng Yang, Peng An, Wensen Jing, Lin Liu, Zhi Yang, Mingyi Yang

“…Data on 23 m6A regulators and 25 cuproptosis-related genes were sourced from the latest literature. …”
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Neuropsychological and clinical variables associated with cognitive trajectories in patients with Alzheimer's disease by Marianna Riello, Monica Moroni, Stefano Bovo, Flavio Ragni, Manuela Buganza, Raffaella Di Giacopo, Marco Chierici, Lorenzo Gios, Matteo Pardini, Matteo Pardini, Federico Massa, Federico Massa, Monica Dallabona, Elisa Vanzetta, Cristina Campi, Cristina Campi, Michele Piana, Michele Piana, Sara Garbarino, Manuela Marenco, Venet Osmani, Giuseppe Jurman, Antonio Uccelli, Antonio Uccelli, Bruno Giometto, Bruno Giometto, NeuroArtP3 Network, Filippo Gerli, Guido Pasquini, Claudia Niccolai, Matteo Betti, Emilio Portaccio, Maria Pia Amato, Rossi Andrea, Parodi Costanza, Ramaglia Antonia, Tortora Domenico, Severino Mariasavina, Andrea Falini, Antonella Castellano, Nicolò Pecco, Paola Scifo, Sonia Calloni

“…Model interpretability analysis revealed that the global cognitive state progression in AD patients is associated with: low spatial memory (Corsi block-tapping), verbal episodic long-term memory (Babcock's story recall) and working memory (Stroop Color) performances, the presence of hypertension, the absence of hypercholesterolemia, and functional skills inabilities at the IADL scores at baseline.ConclusionThis is the first AI study to predict cognitive trajectories of AD patients using routinely collected clinical data, while at the same time providing explainability of factors contributing to these trajectories. …”
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White Matter Imaging Phenotypes Mediate the Negative Causality of Mitochondrial DNA Copy Number on Sleep Apnea: A Bidirectional Mendelian Randomization Study and Mediation Analysis by Ying Q, Wang M, Zhao Z, Wu Y, Sun C, Huang X, Zhang X, Guo J

“…Mitochondrial DNA copy number (mtDNA-CN), an easily accessible biomarker in blood, reflects mitochondrial function. However, the causal relationship between mtDNA-CN and SA remains unclear. …”
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Smooth Moves: Comparing Log Dimensionless Jerk Metrics from Body Center of Mass Trajectory and Wearable Sensor Acceleration During Walking by Paolo Brasiliano, Gaspare Pavei, Elena Bergamini

“…Movement smoothness is a critical metric for evaluating motor control and sensorimotor impairments, with increasing relevance in neurorehabilitation and everyday functional assessments. This study investigates the correlation between two smoothness metrics (Log Dimensionless Jerk): LDLJV, derived from body center of mass (BCoM) trajectories using a gold-standard stereophotogrammetric system, and LDLJA, calculated from acceleration data recorded via an inertial measurement unit (IMU) placed at the L1–L2 level. …”
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Integrated single-cell analysis reveals the regulatory network of disulfidptosis-related lncRNAs in bladder cancer: constructing a prognostic model and predicting treatment respons... by Jiafu Xiao, Jiafu Xiao, Jiafu Xiao, Wuhao Liu, Wuhao Liu, Wuhao Liu, Jianxin Gong, Jianxin Gong, Jianxin Gong, Weifeng Lai, Weifeng Lai, Weifeng Lai, Neng Luo, Neng Luo, Neng Luo, Yingfan He, Junrong Zou, Junrong Zou, Zhihua He, Zhihua He, Zhihua He

“…A prognostic model was constructed through LASSO regression analysis based on DRLs, complemented by multivariate Cox regression analysis. …”
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MRI-based differentiation of Parkinson's disease by cerebellar gray matter volume by Dacong Zhao, Jiang Guo, Guanghua Lu, Rui Jiang, Chao Tian, Xu Liang

“…This study aimed to explore the potential of cerebellar gray matter volume, related to motor control function, as a neuroimaging biomarker to classify patients with PD and healthy controls (HC) by using voxel-based morphometric (VBM) measurements and support vector machine (SVM) methods based on independent component analysis (ICA). …”
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Wind Turbine Static Errors Related to Yaw, Pitch or Anemometer Apparatus: Guidelines for the Diagnosis and Related Performance Assessment by Davide Astolfi, Silvia Iuliano, Antony Vasile, Marco Pasetti, Salvatore Dello Iacono, Alfredo Vaccaro

“…Based on this, finally, a rigorous work flow is formulated for detecting static errors and discriminating among them through SCADA data analysis. Nevertheless, methods based on additional information sources (like further sensors or meteorological data) are also discussed. …”
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Genome-Wide Analysis of the <i>CDPK</i> Gene Family in <i>Populus tomentosa</i> and Their Expressions in Response to Arsenic Stress and Arbuscular Mycorrhizal Fungi Colonization by Minggui Gong, Jiajie Su, Shuaihui Wang, Youjia Wang, Weipeng Wang, Xuedong Chen, Qiaoming Zhang

“…However, there is still limited knowledge regarding the genes of the <i>Populus tomentosa CDPK</i> family and their underlying functions in response to arsenic (As) stress and arbuscular mycorrhizal fungi (AMF) colonization. …”
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Machine Learning System for Predicting Cardiovascular Disorders in Diabetic Patients by A. Mayya, H. Solieman

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Elucidating the causal associations and mechanisms between circulating immune cells and idiopathic pulmonary fibrosis: new insights from Mendelian randomization and transcriptomics by Han Yang, Xuanyu Wu, Xiang Xiao, Jiajing Chen, Xiaomin Yu, Wen Zhao, Fei Wang

“…Subsequently, SNP-nearest genes combined with the transcriptomics data of IPF were subjected to multiple bioinformatics analyses such as TIMER, WGCNA, functional enrichment analysis, protein-protein interaction analysis, and ROC to identify IPF biomarkers. …”
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Boundaries extraction and features recognition of metro station catchment area: the perspective of cognition and perception by Jiaqi Zhao, Qinghuai Liang, Jiaao Guo, Lei Huang

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Genome-Wide Identification and Expression Analyses of the MADS-Box Gene During Flowering in <i>Primulina huaijiensis</i> by Jie Zhang, Xinxia Cai, Qin Liu, Ziyi Lei, Chen Feng

“…The results of qRT-PCR analysis of selected genes further validated the RNA-seq findings, suggesting these genes may exert distinct functional roles during floral development. …”
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Integrating advanced neural network architectures with privacy enhanced encryption for secure and intelligent healthcare analytics by C. Ramesh Babu Durai, S. Dhanasekaran, M. Jamuna Rani, Sindhu Chandra Sekharan

“…Detailed evaluation accepts the performance of structure in maintaining privacy through providing high-demonstration analysis for healthcare data protection. Organized testing and comparative analysis suggest that neuroshield not only improves data security, but also provides excellent accuracy with better performing results in healthcare analytics.…”
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Identification of Coal Mine Infrastructure Facilities with Inefficient Power Consumption by Belyaevsky R.V., Ahmetgareev A.R.

“…The analysis was conducted using Mathcad 15, which allows the calculation of confidence intervals via the inverse Laplace function. …”
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Sleep Disorders in Pediatric Patients Affected by Neurofibromatosis Type 1: Reports of a Questionnaire and an Apple Watch Sleep Assessment by Alessia Migliore, Manuela Lo Bianco, Roberta Leonardi, Stefania Salafia, Claudia Di Napoli, Martino Ruggieri, Agata Polizzi, Andrea D. Praticò

“…<b>Introduction:</b> Sleep is a fundamental biological function critical for physical and mental health. Chronic sleep disturbances can significantly impair cognitive, emotional, and social functioning, leading to deficits in attention, alertness, and executive function, alongside increased irritability, anxiety, and depression. …”
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Spatial Correlation Network Characteristics of Comprehensive Transportation Green Efficiency in China by Qifei Ma, Sujuan Li, Zhenchao Zhang

“…This study employs the slacks-based measure-data envelopment analysis (SBM-DEA) model to assess the CTGE of China. …”
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Extracting Bridge Modal Frequencies Using Stationary Versus Drive-By Modes of Smartphone Measurements by Niall McSweeney, Ramin Ghiasi, Abdollah Malekjafarian, Ekin Ozer

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A spatial bearing fault classification method based on improved APSMOTE-WKMFA by CHEN Chao, YANG Chenhao, XU Haosen, WAN Ouying, HAN Liling

“…Secondly, the projection mapping was performed using the kernel marginal Fisher analysis based on the wavelet function. Finally, the <italic>k</italic>-nearest neighbor classifier algorithm was used to train the classification model on the transformed low-dimensional features. …”
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Statistical model for assessing the reliability of non-destructive testing systems by solving inverse problems by A. E. Alexandrov, S. P. Borisov, L. V. Bunina, S. S. Bikovsky, I. V. Stepanova, A. P. Titov

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