Hypoxia alters the response of ovarian cancer cells to the mitomycin C drug by Aleksandra Gawrylak, Aleksandra Gawrylak, Klaudia Brodaczewska, Roksana Iwanicka-Nowicka, Roksana Iwanicka-Nowicka, Marta Koblowska, Marta Koblowska, Agnieszka Synowiec, Lubomir Bodnar, Lubomir Bodnar, Cezary Szczylik, Bogdan Lesyng, Rafał Stec, Claudine Kieda, Claudine Kieda

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Comparative the efficacy and safety of Gosuranemab, Semorinemab, Tilavonemab, and Zagotenemab in patients with Alzheimer’s disease: a systematic review and network meta-analysis of... by Wenting Cai, Wenting Cai, Hui Zhang, Hui Zhang, Yan Wu, Yan Wu, Yao Yao, Jinping Zhang

“…By investigating the effects of monoclonal antibodies on cognitive function, disease progression, and overall quality of life in patients with AD, which can provide valuable insights into their potential as a therapeutic option for this devastating neurodegenerative disorder.MethodsThe randomized controlled trials (RCTs) investigating the efficacy of Gosuranemab, Semorinemab, Tilavonemab, and Zagotenemab in Alzheimer’s disease (AD) were systematically searched across PubMed, Embase, Web of Science and Cochrane Library, up to May 2024. …”
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Anticancer evaluation of Myo-inositol through carbonic anhydrase IV inhibition activity: A spectroscopic, quantum computational, topological, drug-likeness and in-silico molecular... by K. Rajkumar, V. Gokulakrishnan, S. Anand, R. Durga, G. Senthilkumar, S. Sri Karthick, R. Kayalvizhi Kothai

“…A strong correlation exists between experimental data and theoretical values, indicating that myo-inositol is highly stable. …”
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Tracing the aggregation pathway of the scaffold protein DISC1: Structural implications for chronic mental illnesses by Abhishek Cukkemane, Nina Becker, Tatsiana Kupreichyk, Henrike Heise, Dieter Willbold, Oliver H. Weiergräber

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An Analysis of the Use of Puzzle-Based Learning Media in Enhancing Students' Interest in Science Subjects in Grade V at SD Negeri 19 Tulang Bawang Udik by Asri Nuraini, Masrurotul Mahmudah, Nurul Aisyah

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Digital Inclusion Pathways and Influencing Factors Among Older Adults in Outpatient Settings: A Grounded Theory Study by Chen Y, Yin Q, Zhou T, Gu S, Xie L, Xiao M, Wang L, Zhao Q

“…Physical function, digital health literacy, personal perception, and digital attitudes demonstrated a direct impact on the digital inclusion of older adults. …”
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Fuzzy System for the Quality Assessment of Educational Multimedia Edition Design by Vsevolod Senkivskyy, Liubomyr Sikora, Nataliia Lysa, Alona Kudriashova, Iryna Pikh

“…Quality assessment of multimedia edition design is based on a comprehensive analysis of characteristics that affect the quality of output data, edition processing and content representation. …”
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Analysis of Criticism of Newspaper by Jokowi & Joe Biden regarding the Development of Covid-19 in the IDN Times and NY Times Online Media: Cross-Cultural Pragmatic Studies by Melisa Wulan Purnama, Ni Wayan Sartini

“…This study analyzed ten IDN Times and NY Times news articles using a qualitative descriptive method. The data obtained in this study were through listening and note-taking techniques, because the data in this study were in the form of expressions that contain the function of speech and social criticism. …”
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Durability of benralizumab effectiveness in severe eosinophilic asthma patients with and without chronic rhinosinusitis with nasal polyps: a post hoc analysis from the ANANKE study by Luisa Brussino, Maria Aliani, Elena Altieri, Pietro Bracciale, Maria Filomena Caiaffa, Paolo Cameli, Giorgio Walter Canonica, Giorgio Walter Canonica, Cristiano Caruso, Cristiano Caruso, Stefano Centanni, Fausto De Michele, Stefano Del Giacco, Fabiano Di Marco, Laura Malerba, Francesco Menzella, Girolamo Pelaia, Paola Rogliani, Paola Rogliani, Micaela Romagnoli, Pietro Schino, Jan Walter Schroeder, Gianenrico Senna, Alessandra Vultaggio, Maria D’Amato

“…Earlier studies have shown that benralizumab improves asthma outcomes with greater efficacy if patients present CRSwNP.MethodsThis post hoc analysis of the ANANKE study (NCT04272463) reports data on the long-term effectiveness of benralizumab between SEA patients with and without CRSwNP (N = 86 and N = 75, respectively) treated for up to 96 weeks.ResultsBefore benralizumab initiation, CRSwNP patients displayed longer SEA duration, greater oral corticosteroid (OCS) use and blood eosinophil count. …”
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Deciphering the interaction between the expression of LRP2 served as a mitochondrial metabolism-related gene and prognosis in colon cancer integrating multi-omics analysis by Jie Zhang, Ziyun Liu, Xiaoqing Ma, Zhenyu Shi, Jing Zhao, Yongjie Xie, Xiaobin Shang, Xia Zhang

“…Simultaneously, the expression levels of critical gene were detected in the diverse tissues of COAD by immunohistochemistry (IHC) staining. Transcriptomics data was continuously implemented to compare the discrepancy between the expression levels of the target gene and somatic mutation burden, inspecting the key pathways of the target gene by gene set enrichment analysis (GSEA) and examining its drug sensitivity synthetically in the CellMiner databases. …”
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Attentional dysfunction arises from right frontocentral and occipital network connectivity in Parkinson's disease by Isobel Timothea French, Kuo-Hsuan Chang, Wei-Kuang Liang, Wen-Sheng Chang, Yen-Shi Lo, Yi-Ru Wang, Mei-Ling Cheng, Norden E. Huang, Hsiu-Chuan Wu, Siew-Na Lim, Chiung-Mei Chen, Chi-Hung Juan

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Estimation of Total Suspended Solids Concentration in Streams Using Regression and Artificial Neural Networks Methods by Betül Mete, Sinan Nacar, Adem Bayram, Osman Tuğrul Bak

“…In this study considering total suspended solids (TSS) parameter monitored in a stream watershed, the predictability of upstream values from downstream data was investigated using regression analysis, which were applied to linear, power, exponential, and quadratic functions, and artificial neural networks (ANNs) method. …”
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Crystal structure and Hirshfeld surface analysis of [(R,S)-2,8-bis(trifluoromethyl)quinolin-4-yl](piperidin-2-yl)methanol methanol monosolvate by Dennis Awasabisah, Navamoney Arulsamy, Mason Primrose, Guoxing Lin

“…The intermolecular forces are further analyzed and confirmed by a Hirshfeld surface analysis. DFT structural data computed with the ORCA quantum chemistry program package using the B3LYP/def2-TZVPP basis set compare quite well with the experimental X-ray crystal structural data.…”
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“Where” and “What” Do Adolescent Athletes Learn When It Comes to Food Literacy Compared With Adolescents that Do Not Play Sports? A Gender-Based Thematic Analysis by Alysha L Deslippe, Coralie Bergeron, Olivia Y Wu, Kimberley J Hernandez, Emilie Comtois-Rousseau, Tamara R Cohen

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Comprehensive natural resources evaluation from multi-category aggregation: a case study of Huanggang by Xuebo Weng, Xianbin Shi, Xiaoning Zhou, Shuai Leng, Jingmeng Huang, Shaonan Peng

“…We collected data for Huanggang City, China, for the years 2020–2022, converted them into plane data, and applied multi-criteria decision analysis to examine the natural resource characteristics of Huanggang, which has 10 county-level administrative regions. …”
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Exploration of M2 macrophage-related biomarkers and a candidate drug for glioblastoma using high-dimensional weighted gene co-expression network analysis by Suyin Feng, Suyin Feng, Suyin Feng, Long Zhu, Long Zhu, Long Zhu, Jinyuan Gu, Kun Kou, Yongtai Liu, Guangmin Zhang, Hua Lu, Honglai Zhang, Runfeng Sun, Runfeng Sun

“…Herein, our current study aimed to identify gene biomarkers relevant to M2 macrophages using high-dimensional weighted gene co-expression network analysis (hdWGCNA) and predict a candidate drug for GBM.MethodsSingle-cell RNA sequencing (scRNA-seq) data (GSE162631) and expression data (GSE4290) for GBM were obtained from the Gene Expression Omnibus (GEO) database. …”
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Parallel CUDA-Based Optimization of the Intersection Calculation Process in the Greiner–Hormann Algorithm by Jiwei Zuo, Junfu Fan, Kuan Li, Qingyun Liu, Yuke Zhou, Yi Zhang

“…The Greiner–Hormann algorithm is a commonly used polygon overlay analysis algorithm. It uses a double-linked list structure to store vertex data, and its intersection calculation step has a significant effect on the overall operating efficiency of the algorithm. …”
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Impact and mechanisms of organic agriculture development on rural return migration: Based on a perspective of post-productivism by HU Xia, LUO Chongjia, ZHANG Qingyong, ZHOU Xuhai

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Unmasking Machine Learning With Tensor Decomposition: An Illustrative Example for Media and Communication Researchers by Yu Won Oh, Chong Hyun Park

“…As online communication data continues to grow, manual content analysis, which is frequently employed in media studies within the social sciences, faces challenges in terms of scalability, efficiency, and coding scope. …”
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Spatial heterogeneity of forest carbon stocks in the Xiangjiang river Basin urban agglomeration: analysis and assessment based on the multiscale geographically weighted regression... by Yingfeng Kuang, Xiaolong Chen

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