Effects of oral supplementation of β -hydroxy-β -methylbutyrate on muscle mass and strength in individuals over the age of 50: a meta-analysis by Nan Li, Nan Li, Shanbin Chen, Yuxi He, Yamin Chen, Xiaosa Duan, Wenxing He, Qihe Wang, Sana Liu, Tongbo Liu, Haiqin Fang

“…Subgroup analysis revealed that the effect of a dosage of 3 g/d had significant improvement, and the effect of supplementation duration lasting > 12 weeks had significant improvement, and a dosage of 3g/day for more than 12 weeks was recommended.ConclusionHMB oral supplementation can improve muscle mass, strength, and physical function. …”
Get full text

A Predictive Disease Risk Model for Ankylosing Spondylitis: Based on Integrated Bioinformatic Analysis and Identification of Potential Biomarkers Most Related to Immunity by Wenxin Gao, Ruirui Hou, Yungang Chen, Xiaoying Wang, Guoyan Liu, Wanli Hu, Kang Yao, Yanke Hao

“…To identify differentially expressed genes and create a gene coexpression network between AS and healthy samples, we downloaded the AS-related datasets GSE25101 and GSE73754 from the GEO database and employed weighted gene coexpression network analysis (WGCNA). We used the GSVA, GSEABase, limma, ggpubr, and reshape2 packages to score immune data and investigated the links between immune cells and immunological functions by using single-sample gene set enrichment analysis (ssGSEA). …”
Get full text

Investigating the neurovascular coupling across multiple motor execution and imagery conditions: a whole-brain EEG-informed fMRI analysis by Elena Bondi, Yidan Ding, Yisha Zhang, Eleonora Maggioni, Bin He

“…The complementary strengths of electroencephalography (EEG) and functional magnetic resonance imaging (fMRI) have driven extensive research into integrating these two noninvasive modalities to better understand the neural mechanisms underlying cognitive, sensory, and motor functions. …”
Get full text

Argatroban in patients with acute ischemic stroke with early neurological deterioration: a cost-effectiveness analysis from the perspective of Chinese healthcare system by Yu Xie, Liping Hu, Ping Xu, Xianbin Guo, Junxiu Cai, Min Pan, Jie Tang, Qingtao Gong, Rong Su, Yake Lou, Yan Liu, Li Wang, Ying Yu

“…Background and ObjectiveStudies have shown that argatroban improves 90-day functional outcomes in patients with acute ischemic stroke (AIS) with early neurological deterioration (END). …”
Get full text

Differential Proteomic Analysis of Human Placenta-Derived Mesenchymal Stem Cells Cultured on Normal Tissue Culture Surface and Hyaluronan-Coated Surface by Tzyy Yue Wong, Ying-Hui Chen, Szu-Heng Liu, Mairim Alexandra Solis, Chen-Hsiang Yu, Chiung-Hsin Chang, Lynn L. H. Huang

Get full text

Age-related structural changes in the myenteric nervous plexus ganglion along the anterior wall of the proximal human duodenum: A morphometric analysis by Mandić Predrag, Leštarević Snežana, Filipović Tatjana, Đukić-Macut Nataša, Šaranović Milena

“…Aging is one of the most complex biological processes which probably affect structure and function of the enteric nerve system. However, there is not much available information on this topic, particularly in humans. …”
Get full text

Randomized Controlled Trial of Gastrocnemius Muscle Analysis Using Surface Electromyography and Ultrasound in Different Striking Patterns of Young Women’s Barefoot Running by Yuwei Liu, Justin Fernandez

Get full text

Sevoflurane versus propofol on immediate postoperative cognitive dysfunction in patients undergoing cardiac surgery under cardiopulmonary bypass: a comparative analysis by Na Zhao, Rui Qin, Bin Liu, Dongmei Zhang

Get full text

Bladder recovery by stem cell based cell therapy in the bladder dysfunction induced by spinal cord injury: systematic review and meta-analysis. by Jae Heon Kim, Sung Ryul Shim, Seung Whan Doo, Won Jae Yang, Byung Wook Yoo, Joyce Mary Kim, Young Myoung Ko, Eun Seop Song, Ik Sung Lim, Hong Jun Lee, Yun Seob Song

“…Meta-analysis of the data, including findings from urodynamic studies, was performed using the Mantel-Haenszel method.…”
Get full text

Structural analysis of viral infectivity factor of HIV type 1 and its interaction with A3G, EloC and EloB. by Kauê Santana da Costa, Elcio Leal, Alberto Monteiro dos Santos, Anderson Henrique Lima e Lima, Cláudio Nahum Alves, Jerônimo Lameira

“…In the protocol, a constraints archive was used to define the spatial relationship between the side chains from Cys/His residues and zinc ions that formed the zinc-finger motif that is essential for Vif function. We also performed centroids analysis and structural analysis with respect to the formation of the zinc-finger, and the residue disposal in the protein binding domains. …”
Get full text

DFT-analysis of protolytic equivalents of 5-(aryl)-4-(methyl,amino)-1,2,4-triazole-3(2H)-thione by O. A. Bihdan, N. A. Alk Khalaf

“…The use of modern computer methods in aspects of quantum chemistry and systematic analysis of their results give an idea of the reactivity of organic compounds, as well as to understand the essence of known experimental data, correct predictions, and quantitative estimates. …”
Get full text

Clinical efficacy and complications of 10 surgical interventions for cervical ossification of the posterior longitudinal ligament: an updated systematic review and network meta-ana... by Xiao Chen, Yuanhe Fan, Jie Chen, Hongliang Tu

“…Our search identified both randomized and non-randomized controlled trials compar ing the following surgical interventions: ACDF, ADF, ACCF, ACAF, PDIF, PDF, LC, LP, LF, and VBSO. The extracted data were subjected to network meta-analysis. Our analysis included the following outcome measures: Patient demographic characteristics, Japanese Orthopaedic Association (JOA) scores, JOA improvement rates, overall complication rates, excellent/good recovery rates, cervical lordosis characteristics, Visual Analog Scale (VAS) scores, Neck Disability Index (NDI) scores, surgical duration and intraoperative blood loss. …”
Get full text

Effect of preinitiated glucose-insulin-potassium strategy for patients with undergoing planned percutaneous coronary intervention: a systematic review and meta-analysis by Feng Xu, Chuanbao Li, Huiruo Liu, Rugang Liu, Zeyu Yang

“…Objectives Whether the glucose-insulin-potassium (GIK) should be used as an adjuvant therapy for ischaemic myocardial disease remains controversial nowadays reperfusion era. This meta-analysis aimed to assess the effects of preinitiated GIK for patients undergoing planned percutaneous coronary intervention (PCI).Design Systematic review and meta-analysis.Data sources PubMed, Web of science, MEDLINE, Embase, Cochrane Library and ClinicalTrials.gov were searched through 27 November 2022.Eligibility criteria Only randomised controlled trials involving participants preinitiated with GIK or placebo before planned PCI were included.Data extraction and synthesis Two independent reviewers used standardised methods to search, screen and code included trials. …”
Get full text

Handling of missing component information for common composite score outcomes used in axial spondyloarthritis research when complete-case analysis is unbiased by Christos Polysopoulos, Stylianos Georgiadis, Lykke Midtbøll Ørnbjerg, Almut Scherer, Daniela Di Giuseppe, Merete Lund Hetland, Michael John Nissen, Gareth T. Jones, Bente Glintborg, Anne Gitte Loft, Johan Karlsson Wallman, Karel Pavelka, Jakub Závada, Ayten Yazici, Maria José Santos, Adrian Ciurea, Burkhard Möller, Brigitte Michelsen, Pawel Mielnik, Johanna Huhtakangas, Heikki Relas, Katja Perdan Pirkmajer, Ziga Rotar, Ross MacDonald, Bjorn Gudbjornsson, Irene van der Horst-Bruinsma, Marleen van de Sande, Myriam Riek

“…Methods Individual mean imputation (IMI), the modified formula method (MF), overall mean imputation (OMI), and multiple imputation of missing component values (MI) were assessed either analytically or by means of simulations from available data collected across Europe. Their performance in estimating the means of the Bath Ankylosing Spondylitis Disease Activity Index (BASDAI), the Bath Ankylosing Spondylitis Functional Index (BASFI), and the Ankylosing Spondylitis Disease Activity Score based on C-reactive protein (ASDAS-CRP) in cases where component information was set missing completely at random was compared to the CC approach based on bias, variance, and coverage. …”
Get full text

Microservices for information support of multi-agent systems: methods of collection, monitoring and decision-making by A. A. Bryzgalov

“…The purpose of this article is to develop methods and algorithms of microservice implementation for information support of multi-agent systems that implement the functions of digital twins of the enterprise. Particular attention is paid to the implementation of data collection, monitoring, diagnostics and decision-making functions that ensure effective interaction between product agents and resource agents based on service level agreements (SLAs).Research methods. …”
Get full text

Dual-Oriented Targeted Nanostructured SERS Label-Free Immunosensor for Detection, Quantification, and Analysis of Breast Cancer Biomarker Concentrations in Blood Serum by Mohammad E. Khosroshahi, Christine Gaoiran, Vithurshan Umashanker, Hayagreev Veeru, Pranav Panday

“…Each stage of sensor functionalization, conjugation, and biomarker interaction was verified by UV–Vis spectroscopy. …”
Get full text

Spatiotemporal Analysis and Anomalous Trends of Asia AOD (2001–2024): Insights from a Deep Learning Fusion Model and EOF Decomposition by Yu Ding, Wenjia Ni, Jiaxin Dong, Jie Yang, Shiyao Meng, Siwei Li

“…The fused dataset demonstrates significant improvements over the original MERRA-2 AOD, with an increase in the coefficient of determination (R²) by 0.1065 and a reduction in root mean square error (RMSE) by 0.0369. Spatio-temporal analysis, conducted using Empirical Orthogonal Function (EOF) decomposition, reveals that AOD concentrations across Asia are strongly influenced by anthropogenic factors, including industrial activities, transportation emissions, and biomass burning. …”
Get full text

Multidimensional analysis of sedentary behaviour and participation in Spanish stroke survivors (Part&Sed-Stroke): a protocol for a longitudinal multicentre study by Pablo Bellosta-Lopez, Victor Domenech-Garcia, Maria Pilar López-Royo, Javier Gueita-Rodriguez, Jorge Alegre-Ayala, Julia Blasco-Abadía, Cristina de Diego-Alonso, Almudena Buesa, Patricia Roldán-Pérez, Rafael Giner-Nicolás, Natalie Ann Fini, Alicia Tornero Navarro, Ana Conte Lamenca, Andrea Yerro Astrain, Beatriz Martín Lamata, Carina Salgueiro, Claudia Marín Marín, Diana Ruiz Ramos, Elena Sanz Sanza, Enrique Villa Berges, Fernando Cuesta Ruiz, Inés Cortés Cabeza, Javier Harguindey, Juan Luis Abeledo Alcón, Laura Ares Barge, Leyre Leceaga Gaztambide, Lilian Le Roux, Lourdes Martín Gros, Lucía Díez Fuentes, María Carmen Grácia Sen, María Pilar Pardo Sanz, Paloma Rodríguez Escudero, Paz Cristina Sánchez Lecina, Rebeca Yebra Vilarchao, Sara Beltrán Roche, Verónica Montoya Murillo

“…Introduction Stroke survivors usually experience long-lasting functional, emotional and social consequences that might contribute to sedentary behaviour and participation restrictions, which are important targets to address during rehabilitation. …”
Get full text

Multi-Locus GWAS Mapping and Candidate Gene Analysis of Anticancer Peptide Lunasin in Soybean (<i>Glycine max</i> L. Merr.) by Rikki Locklear, Jennifer Kusumah, Layla Rashad, Felecia Lugaro, Sonia Viera, Nathan Kipyego, Faith Kipkosgei, Daisy Jerop, Shirley Jacquet, My Abdelmajid Kassem, Jiazheng Yuan, Elvira de Mejia, Rouf Mian

Get full text

Analysis of factors affecting patterns of Rural Housing Developments, with an Emphasis on Identity (Case Study: East Eghbal Rural District of Qazvin Province)

“…According to the research done on the traditional and modern elements of rural housing, most rural houses lack a traditional texture and have followed the modern urban pattern in deleting the productive functions. Also the analysis of the modern factors in rural housing has shown that most houses have followed an urban construction, the reason for which can be the short distance between these villages and Qazvin itself. …”
Get full text