Six Novel Loci Associated with Circulating VEGF Levels Identified by a Meta-analysis of Genome-Wide Association Studies. by Seung Hoan Choi, Daniela Ruggiero, Rossella Sorice, Ci Song, Teresa Nutile, Albert Vernon Smith, Maria Pina Concas, Michela Traglia, Caterina Barbieri, Ndeye Coumba Ndiaye, Maria G Stathopoulou, Vasiliki Lagou, Giovanni Battista Maestrale, Cinzia Sala, Stephanie Debette, Peter Kovacs, Lars Lind, John Lamont, Peter Fitzgerald, Anke Tönjes, Vilmundur Gudnason, Daniela Toniolo, Mario Pirastu, Celine Bellenguez, Ramachandran S Vasan, Erik Ingelsson, Anne-Louise Leutenegger, Andrew D Johnson, Anita L DeStefano, Sophie Visvikis-Siest, Sudha Seshadri, Marina Ciullo

“…We explored biological links between genes in the associated loci using Ingenuity Pathway Analysis that emphasized their roles in embryonic development and function. …”
Get full text

Cloning, Expression, and Bioinformatics Analysis of the <i>AvFD1</i> Gene in <i>Amomum villosum</i> Lour by Duo Wang, Yating Zhu, Shuang Li, Hongyou Zhao, Chongnan Wang, Qianxia Li, Yanfang Wang, Chunyong Yang, Ge Li, Yanqian Wang, Lixia Zhang

“…The obtained sequence establishes essential molecular data for subsequent functional validation of <i>AvFD1</i> in <i>A. villosum</i>.…”
Get full text

Subcellular object quantification with Squassh3C and SquasshAnalyst by Aurélien Rizk, Maysam Mansouri, Kurt Ballmer-Hofer, Philipp Berger

“…Squassh3C extends the functionality of Squassh to three fluorescence channels and live-cell movie analysis. …”
Get full text

Identification of key modules and hub genes for sepsis-induced myopathy using weighted gene co-expression network analysis by Siming Lin, Siming Lin, Siming Lin, Kexin Cai, Kexin Cai, Kexin Cai, Ai Chen, Weibin Wu, Guili Lian, Shaodan Feng, Shaodan Feng, Zhihong Lin, Zhihong Lin, Liangdi Xie, Liangdi Xie, Liangdi Xie, Liangdi Xie, Liangdi Xie

“…To further analyze the data, we applied weighted gene co-expression network analysis (WGCNA) to distinguish critical gene clusters associated with SIM. …”
Get full text

The association between secondhand smoke exposure and accelerated biological aging: A population-based study and Mendelian randomization analysis by Yue Zhu⁺, Yufan Gao⁺, Yangguang Lu⁺, Yukai Wang, Ziyu Pan, Huixiang Sheng, Jiajun Li, Yinuo Chen, Jialing Lou, Feng Chen, Fajing Yang

“…Methods This study combines secondary dataset analyses and Mendelian randomization analyses. Data from the NHANES 1999–2010 cycles were used, with serum cotinine levels indicating SHS exposure and phenotypic age, derived from age and clinical biomarkers reflecting inflammation, metabolism, and hematologic function, as the measure of biological aging. …”
Get full text

Correlation of Immune Parameters in Breast Cancer Patients Undergoing General Anesthesia: post-hoc Analysis of the TeMP Study by Kristina K. Kadantseva, Valery V. Subbotin, Mikhail Y. Yadgarov, Elizaveta M. Korolenok, Levan B. Berikashvili, Roman A. Akchulpanov, Nikolay S. Karnaukhov, Ksenia S. Korchagina, Polina I. Kukina, Oksana A. Svitich, Artem N. Kuzovlev, Anna S. Barmina, Valery V. Likhvantsev

“…Aim: to study the correlation of immune parameters in breast cancer patients undergoing general anesthesia and to evaluate the 1-year overall and recurrence-free survival after surgery depending on general anesthesia technique.Materials and Methods. A post hoc analysis of data from a double-blind, randomized, controlled clinical trial involving 98 patients with operable breast cancer was performed. …”
Get full text

Clustering analysis of volatile organic compound biomarkers with tobacco exposure and the association with cardiovascular health outcomes in an observation study cohort by Juan Zhao, Haoyun Hong, Joseph Zhai, Remy Poudel, Sanjay Srivastava, Andrew C. Stokes, Pawel K. Lorkiewicz, Tian Jiang, Rose Marie Robertson, Aruni Bhatnagar, Jennifer L. Hall, Naomi M. Hamburg, Rachel J. Keith

“…We applied unsupervised K-Means clustering on the creatinine-adjusted VOC metabolite data and explored the association between each cluster and blood pressure, adjusting for age, sex, and race. …”
Get full text

Intensified Drought Threatens Future Food Security in Major Food-Producing Countries by Zihao Liu, Aifeng Lv, Taohui Li

Get full text

Study of regional energy systems using the technocentric approach by Zavyalov N.V., Paskar I.N., Lebedev G.M.

“…The article analyzes the functioning Kuzbass energy system in three projections according to the two studied criteria, processes and describes the results of the study, evaluates electricity consumption by economic sectors of the Russian Federation, describes in detail the mathematical software to implement the study based on the technocentric approach, finds points of the proposed optimization impact, which justify the implementation of distributed generation facilities (including - on the o Ranking analysis in the course of the conducted research includes three stages, which allow to describe complex technological systems as a result: interval estimation, rationing and forecasting. …”
Get full text

Research on Visualization Techniques Based on Chinese Texts by Hai Yuan, Kang Chen, Caixia Tao, Chong Chen

“…The text visualization process was introduced at first, including information collection, preprocessing, visual presentation and interactive functions. Then based on the analysis of various Chinese text visualization tools, the visualization technology areas such as multi-based tag cloud, tree map, association and time sequences were researched. …”
Get full text

Imputation models and error analysis for phase contrast MR cerebral blood flow measurements in heterogeneous pediatric and adult populations by Eamon K. Doyle, Eamon K. Doyle, Isabel Torres, Isabel Torres, Joseph Liu, Abhishek Karnwal, Sudarshan Ranganathan, Sudarshan Ranganathan, Bradley J. De Souza, Payal Shah, Bradley S. Peterson, John C. Wood, John C. Wood, Matthew Thomas Borzage, Matthew Thomas Borzage, Matthew Thomas Borzage, Matthew Thomas Borzage

Get full text

Efficacy of acupuncture on lower limb motor dysfunction following stroke: A systematic review and meta-analysis of randomized controlled trials. by Peng Chen, Xing Jin, Debiao Yu, Xiaoting Chen, Yaoyu Lin, Fuchun Wu, Bin Shao

“…Review Manager 5.3 and Stata 17.0 were used in data analysis. Results were presented as mean difference (MD) or standardized mean difference (SMD) with 95% confidence interval (95% CI).…”
Get full text

Effect of L-Citrulline on Creatine Kinase MM (CK-MM) Isoenzymes in Mice: An In Vivo Study Focusing on Immunohistochemistry Analysis by Dhoni Akbar Ghozali, Annisa Aghnia Rahma, Shafira Nur Hanifa, Muhana Fawwazy Ilyas

“…The CK-MM expression in skeletal muscle tissue post-eccentric exercise was assessed using immunohistochemistry analysis. The statistical analysis included the Shapiro-Wilk test for data distribution and the Kruskal-Wallis and Mann-Whitney post-hoc tests for significant differences (p<0.05). …”
Get full text

Les réseaux d'enseignants – Quels sont les comportements rédactionnels des locuteurs ? by Isabelle Quentin

“…Most of these teachers are deeply implicated in an association, Les Clionautes, and can be described as innovating teachers. Quantitative data and posted messages analysis allowed us to highlight some implicit functioning rules, which we are presenting in this article.…”
Get full text

GhLPF1 Associated Network Is Involved with Cotton Lint Percentage Regulation Revealed by the Integrative Analysis of Spatial Transcriptome by Hongyu Wu, Luyao Wang, Shengjun Zhao, Mengtao Gao, Junfeng Cao, Yupeng Hao, Li Yu, Ting Zhao, Siyuan Wang, Jin Han, Yumeng Zhu, Yongyan Zhao, Jie Li, Ke Nie, Kening Lu, Linyun Ding, Zhiyuan Zhang, Tianzhen Zhang, Xueying Guan

“…Given these data, it is demonstrated that GhLPF1 mediates a regulation network in LP as a transcriptional repressor, which makes it a valuable functional marker for fiber‐trait improvement application from QTL‐LP‐ChrA06.…”
Get full text

Effects of repeated low-level red light therapy on myopia progression in children: a systematic review and meta-analysis by Haobo Fan, Haobo Fan, Jia Yu, Jia Yu, Aiming Jiang, Aiming Jiang, Qiumei Wei, Xuemin Zhang, Airui Xie, Airui Xie, Junguo Duan, Junguo Duan, Junguo Duan, Junguo Duan

Get full text

Analysis of phosphomotifs coupled to phosphoproteome and interactome unveils potential human kinase substrate proteins in SARS-CoV-2 by Vineetha Shaji, Vineetha Shaji, Ahmad Rafi, Mukhtar Ahmed, Athira Perunelly Gopalakrishnan, Athira Perunelly Gopalakrishnan, Sowmya Soman, Amjesh Revikumar, Ganesh Prasad, Abhithaj Jayanandan, Rajesh Raju

Get full text

Noise Elimination of Reciprocating Compressors Using FEM, Neural Networks Method, and the GA Method by Ying-Chun CHANG, Min-Chie CHIU, Ji-Lin XIE

Get full text

OrchidBase 6.0: increasing the number of Cymbidium (Orchidaceae) genomes and new bioinformatic tools for orchid genome analysis by You-Yi Chen, Ye Sun, Chung-I Li, Shao-Ting Lin, Hao-Chen Zheng, Zhe-Bin Zhang, Bing-Ru Lee, Chun-Lin Hsieh, Yu-Yun Hsiao, Chi-Nga Chow, Chien-Wen Yang, Wen-Chi Chang, Heming Chen, Feng-Xi Yang, Gen-Fa Zhu, Qinyao Zheng, Cheng-Yuan Zhou, Zhuang Zhao, Ye Ai, Lin-Ying Wang, Deqiang Chen, Xin He, Ming-Zhong Huang, Dong-Hui Peng, Hao Yu, Siren Lan, Zhong-Jian Liu, Wei-Sheng Wu, Wen-Chieh Tsai

Get full text

Fatigue life study of the door on the new-type 160 km/h railway box wagon by MA Chengcheng, FU Maohai, AN Qi, WANG Yang

“…The door's fatigue damage was calculated with two analyzing methods, which were the frequency domain analysis based on the stress response power spectrum density function and the time domain analysis based on the rain flow counting method. …”
Get full text