Screening of CAD-related secretory genes associated with type II diabetes based on comprehensive bioinformatics analysis and machine learning by Li Xie, Han Xiao, Maoyu Zhao, Li Xu, Si Tang, Youzhu Qiu

“…Additional analyses included immune analysis, drug sensitivity, competing endogenous RNA (ceRNA) networks, and smooth muscle cell -related functional analysis. …”
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Progressive Response of Repeated Treatment with High-Concentration (179 mg) Capsaicin Patch in Peripheral Neuropathic Pain After Surgical or Traumatic Nerve Injury: Findings from t... by Michael A. Überall, Christian Simanski, Mike Zellnig, Mariëlle Eerdekens, Sylvia Engelen, Myriam Heine, Fabienne Percot, Rita Freitas, Lucia Garcia Guerra, Tamara Quandel

“…Key measures included pain intensity, quality of life (QoL), affective distress, sleep disturbances, and overall functioning. Furthermore, analgesic use and adverse events associated with HCCP treatment were evaluated. …”
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Lipopolysaccharide-binding protein (LBP): a prognostic biomarker for gastric cancer linked to immune infiltration by Hao Lv, Mei Lv, Xuyang Guo, Xiaoman Zhu, Yue Chao, Dandan Li

“…Analytical techniques included volcano plots, protein-protein interaction networks, Gene Ontology (GO) analysis, Kyoto Encyclopedia of Genes and Genomes (KEGG) analysis, gene set enrichment analysis (GSEA), and immune infiltration assessments. …”
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Clinical evidence of acupuncture for amnestic mild cognitive impairment: A systematic review and meta-analysis of randomized controlled trials by Guangyao Lin, Stella Lim Jin Yie, Shanshan Guo, Xuanling Li, Lianwei Xu

“…According to the meta-analysis, acupuncture treatment provided a remarkable improvement in cognitive function as assessed by Mini-Mental State Examination (MD = 1.09, 95 %CI [0.86, 1.31], p < 0.00001), Montreal Cognitive Assessment (MD = 0.93, 95 %CI [0.80, 1.07], p < 0.00001), Alzheimer's Disease Assessment Scale-Cognitive (MD = 1.00, 95 %CI [-1.23, −0.77], p < 0.00001), and P300 latency (MD = −15.40, 95 %CI [-23.68, −7.12], p = 0.0003). …”
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Machine learning driven diabetes care using predictive-prescriptive analytics for personalized medication prescription by Manaf Zargoush, Somayeh Ghazalbash, Mahsa Madani Hosseini, Farrokh Alemi, Dan Perri

“…The BN’s unique dual capability serves both predictive and prescriptive functions. Several BN learning algorithms are applied to map the relationships among patient features and decision variables for predicting the outcome. …”
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Early detection of chemotherapy-induced cardiotoxicity in breast cancer patients: a comprehensive analysis using speckle tracking echocardiography by Ning Zhang, Na Wang, Yanyan Zhang, Ya Liu, Miaomiao Pei, Gaiqin Liu, Xinle Jia, Xuejia Guo

“…Logistic regression analysis highlighted the additive predictive value of integrating biomarker data with advanced imaging findings to identify patients with the highest risk of significant cardiotoxicity.DiscussionThe study concluded that an integrated diagnostic approach, combining detailed imaging assessments with sensitive biomarker analysis, offers a superior strategy for the early detection of chemotherapy-induced cardiotoxicity in breast cancer patients. …”
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Abstract 246: Effect of platelet count on outcome in ischemic stroke patients with LVO undergoing MT;a meta‐analysis by Muhammad Tayyab Muzaffar, Ahmad  , Mishal  , Hafiz Mohammad Maaz, Atrooba Zahid, Haris Kamal, Muhammad K Ahmed

“…Conclusion Our meta‐analysis revealed that compared to individuals with normal platelet count, those with platelet count (< 150,000 /μL) had worse functional outcomes (MRS ≤ 2) , higher mortality rates, and a greater incidence of sICH. …”
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Ecohydrology and paleoenvironment of the Cretaceous (Albian) Cloverly Formation: insights from multi-taxon oxygen isotope analysis of vertebrate phosphates by M. L. Allen, M. B. Suarez, T. L. Adams, C. A. Suarez

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Leveraging hybrid model of ConvNextBase and LightGBM for early ASD detection via eye-gaze analysis by Ranjeet Bidwe, Sashikala Mishra, Simi Bajaj, Ketan Kotecha

“…This research introduces a novel method for eye gaze analysis to identify autistic traits in children. This proposed work offers • A novel method of ConvNextBase and LightGBM leveraging eye position as a feature for early detection of autistic traits. • A new ConvNextBase architecture proposed with few unfreezed layers and extra dense layers with units of 512 and 128, respectively, and dropout layers with a rate of 0.5 that extract rich, high-level, and more complex features from the images to improve generalization and mitigate overfitting. • A LightGBM model performed classification using 3-fold cross-validation and found the best parameters for bagging_function, feature_fraction, max_depth, Number_of_leaves and learning_rate with values of 0.8, 0.8, −1, 31 and 0.1 respectively, to improve the model's robustness on unseen data.This proposed method is trained and tested on the publicly available Kaggle dataset, and results are benchmarked with other state-of-the-art methods. …”
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YOLOv8-Based Estimation of Estrus in Sows Through Reproductive Organ Swelling Analysis Using a Single Camera by Iyad Almadani, Mohammed Abuhussein, Aaron L. Robinson

“…This calibration helped establish a functional relationship between the measurements on the image (such as the distances between the labia and from the clitoris to the perineum, and the vulva perimeter) and the depth distance to the camera, which enabled accurate adjustments and calibration for our analysis. …”
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Gene expression profiling in pure neural leprosy: insights into pathogenesis and diagnostic biomarkers by Mariana Martins de Athaide, Thyago Leal-Calvo, Tatiana Pereira Da Silva, Thabatta Leal Silveira Andrezo Rosa, Helen Ferreira, Bernardo Miguel de Oliveira Pascarelli, Ana Caroline Siquara de Sousa, Marcia Rodrigues Jardim, Marcia Rodrigues Jardim, Marcia Rodrigues Jardim, Marcia Rodrigues Jardim, Marcia Rodrigues Jardim, Roberta Olmo Pinheiro, Roberta Olmo Pinheiro, Roberta Olmo Pinheiro

“…Downregulated genes included GAS2L2, TRIM67, IL1RAPL1, MAP1LC3B2, and NTNG1, implicated in neuronal development and autophagy, while upregulated genes were linked to immune responses. Functional analyses highlighted inflammasome activation and autophagy impairment in PNL, correlating with nerve inflammation and architecture loss.DiscussionWe hope that our data will aid in identifying new markers, fostering strategies for early diagnosis, preventing disabilities, and improving the management of PNL patients.…”
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Composition and characterization of substantive statements of strategic planning tasks: analysis of changes in the conditions of the formation of a digital management platform by O. M. Pisareva

“…In this regard, the main goal of the work is to study aspects of the impact of digital transformation on the composition and characteristics of strategic planning tasks.Methods: the study was carried out based on a systematic approach to the study of socio-economic systems and processes using the methods of logical and comparative analysis, methods of statistical analysis of indicators of the functioning of the strategic planning system in the Russian Federation, providing the necessary depth of consideration of scientific problems.Results: the author presented an analysis of scientific and practical publications on the research topic, as well as the composition, functional and substantive capabilities of an automated information system for supporting strategic planning. …”
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Physical activity for children and adolescents with attention deficit hyperactivity disorder: a protocol of a systematic review and meta-analysis by Ole Jakob Storebø, Marie-Louise Jensen, Merete Bender Bjerrum, Marianne Vamosi

“…Furthermore, it will be the first review in the field to include QoL as an outcome and to apply trial sequential analysis as part of the meta-analysis.Ethics and dissemination As the systematic review is a secondary analysis of data from primary trials, approval from an ethics committee is not required. …”
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A systematic comparative analysis of gait characteristics in patients undergoing total knee arthroplasty and unicompartmental knee arthroplasty: a review study by Ming Zhang, Haoyue Wang, Zhiwei Cai, Haochong Zhang, Yifei Zhao, Xiaoran Zu, Cheng Wang, Xiang Li

“…Following stringent selection criteria, data were synthesized from studies involving 171 TKA and 148 UKA patients, focusing on reported gait outcomes and aggregating findings for comprehensive analysis. …”
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Application of deep learning models on single-cell RNA sequencing analysis uncovers novel markers of double negative T cells by Tian Xu, Qin Xu, Ran Lu, David N. Oakland, Song Li, Liwu Li, Christopher M. Reilly, Xin M. Luo

“…Together, our comprehensive analysis has uncovered and validated novel markers for different subpopulations of DNT cells that can be used in the phenotypic and/or functional characterization of these relatively rare cells in health and disease.…”
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Long-Term Performance Analysis of Direct Photovoltaic Thermal-Assisted Heat Pump Water Heater Using Computational Model by Demiss Alemu Amibe, Alemayehu Tenaw Eneyaw

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A Novel Double Cluster and Principal Component Analysis-Based Optimization Method for the Orbit Design of Earth Observation Satellites by Yunfeng Dong, Xiaona Wei, Lu Tian, Fengrui Liu, Guangde Xu

“…To address these two problems, a cluster and principal component analysis-based optimization method (CPC-based OM) is proposed, in which many candidate orbits are gradually randomly generated until the optimal orbit is obtained using a data mining method, that is, cluster analysis based on principal components. …”
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Modeling forest and rangeland ecosystem responses to drought across Hyrcanian bioclimatic zones of Iran using GLM and LAI analysis by Azade Bazrmanesh, Saeid Soltani, Mostafa Tarkesh Esfahani, Reza Jafari

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Analysis of the Impact of Reservoir Development on the Availability of Water for Paddy Farming in Sanjai Village, East Sinjai District, Sinjai Regency by La Sumange, Jamal Jamal

“…The method used to analyse the data was descriptive analysis and paired sample mean different test. …”
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Multi-level analysis of the enamel microstructure in the substantiation of microinvasive technologies of treatment of focal demineralization of enamel in patients of orthodontic pr... by O. S. Gileva, A. D. Levitskaya, E. S. Syutkina, I. N. Khalyavina

“…The results of a multilevel (macro-, meso- and microscopic) analysis of the structure and micromechanical properties of enamel in the focus of demineralization made it possible to assess the validity of the developed experimental methods for artificial caries of enamel, to obtain voluminous information about the structural and functional disorders developing in it, to justify the expediency of the pathogenetic use of the microinvasive infiltration treatment method.…”
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