Suggested Topics within your search.
Suggested Topics within your search.
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7582
Exploring NUP62’s role in cancer progression, tumor immunity, and treatment response: insights from multi-omics analysis
Published 2025-03-01“…This study used multi-omics analyses combined with experimental validation in gastric cancer to investigate the expression, functional characteristics, and clinical relevance of NUP62 in cancer.MethodsData from TCGA, GTEx, and CPTAC databases were used to analyse the expression, mutation characteristics, and clinical associations of NUP62. …”
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7583
Genome-wide identification, transcriptional profiling, and miRNA-binding site analysis of the LBD gene family in the camphor tree
Published 2025-06-01“…Despite multiple published C. camphora genome assemblies, functional characterization of LBD transcription factors in this species remains limited. …”
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7585
Analysis of technical efficiency and socio-economic factors influencing the development of smallholder oil palm plantations in Batanghari Regency, Indonesia
Published 2023-02-01“…The analytical methods employed include descriptive analysis and the Stochastic Frontier Production Function with the Maximum Likelihood Estimation (MLE) method. …”
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7586
Identification and Validation of LYZ and CCL19 as Prognostic Genes in the Cervical Cancer Micro-Environment
Published 2022-06-01“…We performed large-scale data analysis through a global gene expression profile. …”
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7587
Analysis of risk factors for hypoxemia in PACU for patients undergoing thoracoscopic lung cancer resection based on logistic regression model
Published 2025-04-01“…Results Among the 398 patients studied, 149 (37.4%) experienced hypoxemia. Univariate analysis indicated significant differences in age, BMI, height, ASA classification, hypertension, diabetes, lung function test with Forced Expiratory Volume at 1 s / Forced Vital Capacity (FEV1/FVC), and awakening time between the groups. …”
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7588
Genome-wide identification of castor bean class III peroxidase genes and analysis of expression patterns under abiotic stresses
Published 2025-07-01“…Conclusions These findings provide new insights into the composition, evolution, and function of the castor RcPRX gene family and provide a basis for subsequent exploration of gene function.…”
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7589
Causal relationship between inflammatory cytokines and posttraumatic stress disorder: a Mendelian randomization study and potential mechanism analysis
Published 2025-12-01“…The causality between inflammatory cytokines and PTSD risk remains unclear.Methods: We conducted a bidirectional two-sample Mendelian randomization (MR) study using genome-wide association study (GWAS) data from 41 inflammatory cytokines and PTSD. Additional analyses included differential gene expression, protein–protein interaction, and functional enrichment to explore underlying mechanisms.Results: MR analysis indicated that higher levels of stem cell factor (SCF) and interleukin-4 (IL-4) are associated with a reduced risk of PTSD. …”
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7590
Load Model Construction and Parameter Identification Method of Inverter-Interfaced Distributed Generator
Published 2024-11-01“…Combined with the sample data, the unified model identification process was given. …”
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7591
Clinical efficacy of different therapeutic options for knee osteoarthritis: A network meta-analysis based on randomized clinical trials.
Published 2025-01-01“…The data obtained were subjected to statistical analysis and graphical representation using Stata 17.0 software.…”
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7592
Association of Peroxisome Proliferator-Activated Receptors (PPARs) with Diabetic Retinopathy in Human and Animal Models: Analysis of the Literature and Genome Browsers
Published 2020-01-01“…Despite a large number of documented sequence variants of the PPAR genes available in genome browsers, researchers usually focus on a small set of previously reported variants. Data extraction from Ensembl genome browser revealed several sequence variants with predicted deleterious effect on protein function which present candidates for further experimental validation. …”
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7593
Analysis of rare coding variants in 470,000 exome-sequenced subjects characterises contributions to risk of type 2 diabetes.
Published 2024-01-01“…<h4>Materials and methods</h4>Exome sequence data for 470,000 UK Biobank participants was analysed using a combined phenotype for T2D obtained from diagnostic and prescription data. …”
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7594
A bioinformatic analysis to systematically unveil shared pathways and molecular mechanisms underlying monkeypox and its predominant neurological manifestations
Published 2025-07-01“…Functional enrichment analysis through ToppGene provided insights into molecular functions, biological processes, and cellular components associated with these target genes. …”
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Evidence-based approach to the shoulder examination for subacromial bursitis and rotator cuff tears: a systematic review and meta-analysis
Published 2024-12-01“…An accurate and efficient diagnostic strategy focused on physical examination findings may lead to improved outcomes and less functional disability. Objective To identify the most accurate physical examination tests for the diagnosis of RCT and SIS, we performed a systematic review and meta-analysis. …”
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7596
Multi-keyword public key searchable encryption scheme with pattern hiding
Published 2025-03-01“…Each user was allowed to encrypt/upload data and search all authorized encrypted data by the multi-writer/multi-reader capability. …”
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7597
Prediction of recurrence after surgery for pituitary adenoma using machine learning- based models: systematic review and meta-analysis
Published 2025-07-01“…Conclusion AI-based models show strong predictive power for recurrence in both functional and non-functional pituitary adenomas, with an average accuracy above 80%. …”
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Novel genes involved in vascular dysfunction of the middle temporal gyrus in Alzheimer’s disease: transcriptomics combined with machine learning analysis
Published 2025-12-01“…We carried out single-cell transcriptomic analysis of the middle temporal gyrus in the brains of patients with Alzheimer’s disease and healthy controls, revealing obvious changes in vascular function. …”
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The efficacy of platelet-rich plasma preparation protocols in the treatment of osteoarthritis: a network meta-analysis of randomized controlled trials
Published 2025-06-01“…Leukocyte-poor PRP with high platelet concentration increase, using anticoagulant without activator was most effective for WOMAC function and stiffness at 12–18 months (WMD = 18.94; 95% CrI, 8.34–28.12). …”
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