A Comparative Analysis of Effects of Rehabilitation Services on Symptomatology of Parkinson’s Disease-An Umbrella Review of Systematic Reviews and Meta-Analyses by Zobia Farooq, Rayan Aboakel, Rabeaa Sahar, Zareen Akhtar, Tahira Irshad, Jennifer Geller

Get full text

Therapeutic potential of mesenchymal stem cell-derived extracellular vesicles in ischemic stroke: A meta-analysis of preclinical studies by Xiaoming Zhang, Yibing Guo, Kun Fang, Xiangqian Huang, Duo Lan, Mengqi Wang, Lina Jia, Xunming Ji, Ran Meng, Da Zhou

“…Data extraction and analysis were performed using RevMan 5.3 software. …”
Get full text

A one-year follow-up case series on gait analysis and patient-reported outcomes for persons with unilateral and bilateral transfemoral amputations undergoing direct skeletal fixati... by Diana Toderita, Tiereny McGuire, Alice M. Benton, Charles Handford, Arul Ramasamy, Paul Hindle, Anthony M. J. Bull, Louise McMenemy

“…However, understanding of its impact on musculoskeletal function remains limited. Methods This study compares pre- and 1-year post-osseointegration surgery outcomes, focusing on patient-reported measures and musculoskeletal system function during level-ground walking. …”
Get full text

Relecture de vocabulaires d’architecture : apport de la complexité des représentations numériques dans la caractérisation de formes architecturales by David Lo Buglio

“…By articulating terminology, functional logics and geometrical logics, the semantics of an element can be considered as an architectural concept. …”
Get full text

Outcomes of lateral approach total knee replacement in the elderly cohort: A focused analysis on patients aged 80 and above by Michael Messieh, Steve Nguyen

“…To investigate these relationships, we applied Chi-square tests for categorical data and Analysis of Variance (ANOVA) for continuous variables, facilitating a statistical examination of our hypotheses. …”
Get full text

Evaluating cognitive decline detection in aging populations with single-channel EEG features based on two studies and meta-analysis by Lior Molcho, Neta B. Maimon, Talya Zeimer, Ofir Chibotero, Sarit Rabinowicz, Vered Armoni, Noa Bar On, Nathan Intrator, Ady Sasson

“…This comprehensive report presents findings from two studies and a meta-analysis, involving a total of 237 senior participants, aimed at investigating cognitive function in aging populations. …”
Get full text

CRISPR/Cas9-based discovery of ccRCC therapeutic opportunities through molecular mechanism and immune microenvironment analysis by Bo Han, Weiyang Liu, Wanhui Wang, Zhuolun Li, Bosen You, Dongze Liu, Yunfeng Nan, Tiankai Ding, Zhou Dai, Yantong Zhang, Wei Zhang, Qing Liu, Xuedong Li

“…Initial screening identified 11 candidate genes through differential expression analysis and CRISPR functional validation. Using LASSO and Cox regression, we selected five key genes (GGT6, HAO2, SLPI, MELK, and EIF4A1) for model construction. …”
Get full text

Comparative effectiveness of non-pharmacological therapies for postoperative cognitive dysfunction: Protocol for a systematic review and network meta-analysis. by Kexin Wu, Qiongnan Bao, Jun Huang, Shanshan Sun, Yaqin Li, Xinyue Zhang, Manze Xia, Zhenghong Chen, Jin Yao, Wanqi Zhong, Zihan Yin, Fanrong Liang

“…Two reviewers will independently conduct study selection and data extraction. The primary outcome will be the changes in the overall cognitive function before and after the intervention. …”
Get full text

ZNF385B as a potential prognostic and immunotherapy biomarker in ovarian cancer: insights from pan-cancer analysis by Hang Yu, Wei Cheng, Aoshuang Huang, Jing Feng, Dan Zi

“…To support the bioinformatics findings, a series of functional experiments were performed to explore the biological role of ZNF385B. …”
Get full text

Who gets referred for knee or hip replacement? A theoretical model of the potential impact of evidence-based referral thresholds using data from a retrospective review of clinic re... by Andrew J Price, Andrew Judge, Alastair Gray, Rachael Gooberman-Hill, David Beard, Adrian Sayers, Rob Middleton, Stephanie Smith, Karen L Barker, David Murray, Sujin Kang, Elena Benedetto, James Smith, Ray Fitzpatrick, Helen A Dakin, Peter Eibich, Nigel Arden, Andy Carr, Kristina Harris, Elizabeth Gibbons, Jill Dawson, Laura Miller, Elsa Marques, Ashley Blom

“…Objectives To estimate the relationship between patient characteristics and referral decisions made by musculoskeletal hubs, and to assess the possible impact of an evidence-based referral tool.Design Retrospective analysis of medical records and decision tree model evaluating policy changes using local and national data.Setting One musculoskeletal interface clinic (hub) in England.Participants 922 adults aged ≥50 years referred by general practitioners with symptoms of knee or hip osteoarthritis.Interventions We assessed the current frequency and determinants of referrals from one hub and the change in referrals that would occur at this centre and nationally if evidence-based thresholds for referral (Oxford Knee and Hip Scores, OKS/OHS) were introduced.Main outcome measure OKS/OHS, referrals for surgical assessment, referrals for arthroplasty, costs and quality-adjusted life years.Results Of 110 patients with knee symptoms attending face-to-face hub consultations, 49 (45%) were referred for surgical assessment; the mean OKS for these 49 patients was 18 (range: 1–41). …”
Get full text

Unraveling the causal relationship and underlying mechanisms between cathepsins on liver cancer: findings from mendelian randomization and bioinformatics analysis by Xiaoxue Wang, Zexin Zhu

“…To assess heterogeneity and pleiotropy, we conducted the MR-Egger intercept test, Cochran’s Q test, as well as the MR-Pleiotropy RESidual Sum and Outlier (MR-PRESSO) analysis, along with the leave-one-out analysis. After that, bioinformatic analysis based on the Gene Expression Omnibus (GEO) databases were utilized, Gene ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) functional enrichment analysis were utilized for exploring the underlying mechanisms. …”
Get full text

Left Ventricular Dyssynchrony Parameters Measured by Phase Analysis of Post-stress and Resting Gated SPECT Myocardial Perfusion Imaging by Yanli Zhou, Dianfu Li, Jianlin Feng, Donglan Yuan, Zenic Patel, Kejiang Cao, Ji Chen

“…Sixty normal subjects, 40 patients with stress-induced ischemia but normal LV function, and 29 patients with LV dysfunction were included in this study. …”
Get full text

INDICATORS OF BIOELECTRICAL ACTIVITY OF THE PROPER MASSETER MUSCLES WITH THEIR DIFFERENT MASS IN MALES by O.V. Rybalov, Yu.I. Semenenko, P.I. Yatsenko, O.I. Yatsenko, O.S. Ivanytska

Get full text

Exploring needs analysis of English language training: An evidence from small hotel and restaurant employees in Nusa Lembongan, Bali, Indonesia by Ni Luh Nyoman Seri Malini, Ni Wayan Sukarini, Ida Bagus Putra Yadnya, Sang Ayu Isnu Maharani

“…The data for this mixed-method design study were taken a set of questionnaires on the needs, functions, and problems of using English in the tourism industry distributed to 36 respondents, observation, and interviews with employees as students and administrators. …”
Get full text

Comparing cognitive impairment using MACFIMS in patients with multiple sclerosis and healthy controls: a systematic review and meta-analysis by Amirreza Nasirzadeh, Mohammad Mohammadi, Melika Arab Bafrani, Aynaz Mohammadi, Hossein Bakhtiari-Dovvombaygi

“…Methods This systematic review and meta-analysis aimed to evaluate cognitive function using the Minimal Assessment of Cognitive Function in Multiple Sclerosis (MACFIMS) battery among pwMS patients and healthy controls (HCs). …”
Get full text

NEGOTIATING COMMON GROUND IN COMPUTER-MEDIATED VERSUS FACE-TO-FACE DISCUSSIONS by Ilona Vandergriff

“…A number of factors, including communicative purpose or medium are hypothesized to affect the use of such strategies (Clark & Brennan, 1991). In the data analysis, I 1) identify specific types of reception strategies, 2) compare their relative frequencies by communication medium, by task, and by learner and 3) describe how these reception strategies function in the discussions. …”
Get full text

The Bosnian Discourse Marker PA in Answer Sequences to WH-Questions in Doctor-Patient Interaction: A Conversation Analysis Perspective by Minka Džanko

“…The study examines the function of the turn-initial Bosnian discourse marker PA in patients’ responses to doctors’ wh-questions during the history-taking phase. …”
Get full text

Relationship Between the Anteroposterior Acceleration of Lower Lumbar Spine and Pelvic Tilt Movements During Running by Yoshiaki Kubo, Koji Koyama, Taichi Kimura

“…The pelvic tilt angle during running was calculated through two-dimensional motion analysis. Subsequently, a simple linear regression analysis was employed to clarify the relationship between the acceleration data of the lower lumbar region and the pelvic tilt angle during running. …”
Get full text

A systematic review and meta-analysis of neuromuscular electrical stimulation post-botulinum toxin injection in children with cerebral palsy by Fu-An Yang, Jie-Ren Mi Le, Chia-Hsiang Lu, Chao-Chun Huang, Hung-Chou Chen

“…We included 5 randomized controlled trials in this meta-analysis. NMES treatment following BTX injection resulted in greater functional performance outcomes compared with BTX injections alone (standardized mean difference = 0.57; 95% CI = 0.22 to 0.92). …”
Get full text

Influence of glucagon-like peptide-1 receptor agonists on renal parameters: a meta-analysis of randomized controlled trials by Wenjing Li, Xiaoyan Liang, Na Sun, Daqing Zhang

“…Weighted mean differences (WMD) and 95% confidence intervals (CIs) were calculated for continuous variables using meta-analysis. The primary outcomes were composite renal function parameters, including serum creatinine (Cr) levels, estimated glomerular filtration rate (eGFR), urinary albumin excretion (UAE), and urinary albumin-to-creatinine ratio (UACR). …”
Get full text