Transcriptome analysis reveals common and distinct mechanisms for sheepgrass (Leymus chinensis) responses to defoliation compared to mechanical wounding. by Shuangyan Chen, Yueyue Cai, Lexin Zhang, Xueqing Yan, Liqin Cheng, Dongmei Qi, Qingyuan Zhou, Xiaoxia Li, Gongshe Liu

“…A comparative transcriptomic analysis of the sequencing data was conducted. In total, 1,836 and 3,238 genes were detected with significant differential expression levels after wounding and defoliation, respectively, during one day. …”
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Comprehensive analysis of skin growth-related hub genes and microenvironment characterization in a mouse expanded skin model by Yinmin Wang, Wenxiao Qi, Shun Yu, Xianyu Zhou, Xiuxia Wang, Fei Liu, Fei Liu, Rui Jin, Xusong Luo, Qiangliang Ma, Lin Lu, Jun Yang

“…Understanding the cellular and molecular mechanisms and identifying hub genes and key cell types associated with skin expansion could help predict the success of skin growth during expansion procedures.MethodsWe analyzed murine chip sequencing data and single-cell sequencing data available from the Gene Expression Omnibus database. …”
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Integrated single-cell and transcriptomic analysis of bone marrow-derived metastatic neuroblastoma reveals molecular mechanisms of metabolic reprogramming by Jing Chu, Rong Qin, Shu-Jing Wang, Qiang Wang, Qiang Wu

“…This study aimed to systematically elucidate the molecular mechanisms underlying metabolic reprogramming in bone marrow–infiltrating metastatic NB cells by integrating single-cell transcriptomic data, bulk RNA-sequencing profiles, and in vitro functional validation. …”
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Unveiling the therapeutic potential of senescence-related IQGAP2 in pancreatic Cancer through post-GWAS genomic and scRNA-seq analyses by Zilong Bai, Jiale Liang, Yuanhua Nie, Shilong Wang, Dongmin Chang

“…Method We employed Mendelian randomization (MR) alongside single-cell RNA sequencing (scRNA-seq) to explore the involvement of senescence-associated genes (SAGs) in PC. A summary-data-based MR (SMR) analysis was performed to evaluate the connection between SAG expression and the risk of developing PC, using HEIDI test and colocalization analysis to reduce confounding variables. …”
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Analysis of the Impact of Effectiveness of Media (Seda-va-Sima) Advertisement on the Extent of Consumers’ Urge to Consume National Commodities by Abolfazl Danaei

“…Descriptive statistics were used to investigate the respondents' demographic characteristics, and inferential statistics, structural equation, and path analysis were used to analyze data and test hypothesis. …”
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Parent-Led Applied Behavior Analysis to Impact Clinical Outcomes for Individuals on the Autism Spectrum: Retrospective Chart Review by Anurag Garikipati, Madalina Ciobanu, Navan Preet Singh, Gina Barnes, Frank A Dinenno, Jennifer Geisel, Qingqing Mao, Ritankar Das

“… Abstract BackgroundAutism spectrum disorder (ASD) can have traits that impact multiple domains of functioning and quality of life, which can persevere throughout life. …”
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High-Resolution Numerical Simulation and Impact Analysis of a Severe Convective Weather Process on the Kunming-Vientiane Route by Mei CHEN, Xiaohang WEN, Aijuan BAI, Minhong SONG

“…During March 23 and March 26， 2020， an area along the international route from Kunming， Yunnan to Vientiane， Laos experienced severe weather conditions including hail， thunderstorm winds， and heavy precipitation.A severe convective weather process was simulated using the mesoscale numerical model WRFV4.2 （Weather Research and Forecasting Model） and FNL （Final Operational Global Analysis） data from the National Centers for Environmental Prediction （NCEP）.Hourly weather station data from the China Meteorological Administration was used to check the reliability of the simulation.Furthermore， a diagnostic analysis of various physical quantities output from the WRF model was performed to provide an aviation safety reference for the Kunming-Laos Vientiane route in Yunnan.The results show that： （1） the WRF model can better simulate temperature and precipitable water， but the simulated values of the near-surface wind field are large during the daytime.（2） The simulated output physical quantity field of the simulation can indicate the time and location of severe convective weather， which has certain spatial and temporal forecasting and warning functions and can be used to judge the impact of severe convective weather on flight and the degree of impact according to it.（3） The severe convection was mainly caused by the eastward movement of the Southern Branch Trough， with dry and cold air in the upper levels superimposed on the warm and moist air forming an unstable structure， triggered by the surface convergence lines.Convective available potential energy （CAPE） in the route area is large， and the water vapor conditions are abundant-the rising motion and sinking motion alternate below 9 km altitude， which can cause turbulence during flights.Additionally， the 0 ℃ layer is located at an altitude of about 3 km， which can cause ice to form on the airframe or encounter hail weather， causing a certain impact on flight safety.…”
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A retrospective analysis of early experience with modified complete primary repair of exstrophy bladder (CPRE) in neonates and children by Santosh B. Kurbet, Gowda P. Prashanth, Mahantesh V. Patil, Shivaji Mane

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The effects of kappa opioid agonist RU-1205 on local field potentials and behavior in the discriminative stimulus paradigm by K. Yu. Kalitin, O. Yu. Mukha, A. A. Spasov

“…Compared to the selective kappa-opioid agonist U-50488, the compound RU-1205 induces less significant changes in LFP activity without electrophysiological and behavioral signs of beta-arrestin pathway activation. The overall data suggest that RU-1205 is a functionally selective agonist of kappa-opioid receptors.…”
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Identification of a novel prognostic marker ADGRG6 in pancreatic adenocarcinoma: multi-omics analysis and experimental validation by Han Wu, Han Wu, Jin Shang, Yuanyan Bao, Huajie Liu, Haoran Zhang, Yaosheng Xiao, Yangtaobo Li, Zhaozhang Huang, Xiaolei Cheng, Zixuan Ma, Wenqing Zhang, Pingli Mo, Daxuan Wang, Mingqing Zhang, Yanyan Zhan

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An Analysis of Type-I Generalized Progressive Hybrid Censoring for the One Parameter Logistic-Geometry Lifetime Distribution with Applications by Magdy Nagy, Mohamed Ahmed Mosilhy, Ahmed Hamdi Mansi, Mahmoud Hamed Abu-Moussa

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Evaluating the Effectiveness of Cognitive Interventions for Healthy and Mild Cognitive Impairment Adults: A Comprehensive Umbrella Meta-Analysis by Giuseppe Forte, Francesca Favieri, Ilaria Corbo, Ilaria Chirico, Rabih Chattat, Anna Maria Della Vedova, Anna Pecchinenda, Maria Casagrande

“…Of the 9734 publications that were screened, 25 met the inclusion criteria and reported comprehensive data suitable for statistical analysis. Findings showed that although the effect-sizes across studies were variable, they were consistently positive, indicating a significant impact of different cognitive interventions on global cognitive functioning, memory, executive functions, visuospatial ability, and processing speed compared to control groups. …”
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Mitigation strategies for regional heat island effects: integrated network construction of cold and heat islands by Qunyue Liu, Huimin Zhang, Jiaxin Peng, Qi Li, Ting Liu, Feng Hu, He Huang, Yuanping Shen, Baojian Ye, Yourui Guo, Hongxin Wang

“…By retrieving land surface temperature (LST) from remote sensing data and combining it with Morphological Spatial Pattern Analysis (MSPA) and landscape connectivity analysis, the study constructs connectivity networks for cold and heat islands, optimizing key nodes and corridors using circuit theory. …”
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Historical and sociological analysis of the development of the Russian society in transition as a social dissipative system in a bifurcation zone by I. Yu. Aleksandrova

“…A hypothesis is put forward that if the Russian society is a special case of a dissipative system, its development necessarily obeys the objective laws of development of dissipative systems; therefore, the dynamics of the system of the Russian society during a crisis period should correspond to the patterns of behavior of complex social dissipative systems in the bifurcation zone. Following the analysis of data from empirical sociological studies conducted in Russia at the end of the 20th century, the hypothesis is confirmed. …”
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Free Natural Frequency Analysis of an FG Composite Rectangular Plate Coupled with Fluid using Rayleigh–Ritz Method by Korosh Khorshidi, Ali Bakhsheshy

“…This study investigates natural frequency analysis of an FG composite rectangular plate partially contacting with a bounded fluid. …”
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Multi-omics analysis uncovers the transcriptional regulatory mechanism of magnesium Ions in the synthesis of active ingredients in Sophora tonkinensis by Zhu Qiao, Peng-Cheng Zhou, Zhan-Tao Fan, Fan Wei, Shuang-Shuang Qin, Jing Wang, Ying Liang, Ling-Yun Chen, Kun-Hua Wei

“…Simultaneously, an omics data analysis was conducted on tissue-cultured seedlings subjected to treatments with magnesium and low magnesium. …”
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Ticagrelor or dipyridamole plus aspirin may be a promising antiplatelet therapy in patients with minor stroke or transient ischemic attack: a bayesian network meta-analysis by Shiran Qin, Si Gao, Dandan Xu, Li Zhang, Yanmei Luo, Sitong Guo

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Media Phraseology and the Dynamics of the Ukrainian Language: The Psycholinguistic and Stylistic Paradoxes by Dmytro Syzonov

“…The research and analyzes results collected as material for innovative dictionary of new words and phraseological units (2016-2018) showed, that Ukrainian language integrates itself into the world global process, enriches itself with new lexemes thanks to the English Language, has great psycholinguistic influence from the side of active political processes and connected with the innovations development. The results of the data analysis indicate that the ratio of the new idioms to the new vocabulary in the media in Ukrainian points to the pragmatic specificity of the phraseological resources of the Ukrainian language in the twenty-first century. …”
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Comparing the Effect of Beractant (Beraksurf™) with That of Poractant Alfa (Curosurf®) on the Need for Intermittent Positive Pressure Ventilation in Neonatal Respiratory Distress S... by Yosra Khazani, Sirous Fathi Manesh, Elnaz Shaseb, Parvin Sarbakhsh

“…Abstract Introduction Randomized controlled trial (RCT) data are analyzed by two challengeable adjusted and non-adjusted approaches. …”
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A comprehensive prognostic and immunological analysis of hexokinase domain containing protein-1 (HKDC1) in pan-cancer by Zhi Liang, Tianhao Zhang, Jiajia Huang, Zhixin Huang, Zeyu Zhao, Shirong Cai, Jinping Ma

“…This study seeks to conduct a thorough investigation of HKDC1’s potential functions across thirty-three different tumor types, utilizing data obtained from The Cancer Genome Atlas (TCGA). …”
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