A meta-analysis and review on the effectiveness and safety of renal denervation in managing heart failure with reduced ejection fraction by Quanbin Su, Jiaxin Li, Futian Shi, Jing Yu

“…The quality of the included studies was evaluated utilizing the Cochrane risk assessment tool. The pertinent data were gathered, and a meta-analysis was done using Review Manager 5.3, accompanied by sensitivity and publication bias analyses.Results After applying the inclusion and exclusion criteria, eight randomized controlled trials (RCTs) were selected for analysis, encompassing 314 patients; 154 patients underwent RDN treatment during hospitalization, while 150 were randomized to the control group to receive medication therapy. …”
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Machine learning-assisted multi-dimensional transcriptomic analysis of cytoskeleton-related molecules and their relationship with prognosis in hepatocellular carcinoma by Yuxuan Li, Mingbo Cao, Xiaorui Su, Gaoyuan Yang, Yupeng Ren, Zhiwei He, Zheng Shi, Ziyi Hu, Guirong Liang, Qi Zhang, Zhicheng Yao, Meihai Deng

“…Single-cell sequencing (scRNA-seq) and spatial transcriptomics analyses explored the expression and functional roles of key genes, while drug screening and molecular docking identified potential therapeutic agents, followed by in vitro and in vivo validation. …”
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Integrated metabolomic and transcriptomic analysis reveals the role of root phenylpropanoid biosynthesis pathway in the salt tolerance of perennial ryegrass by Yan-Hua Cao, Zhao-Long Lü, Yuan-Hong Li, Yiwei Jiang, Jin-Lin Zhang

“…Weighted gene co-expression network analysis (WGCNA) based on RNA-Seq data showed that membrane transport and ABC transporters were significantly correlated with salt tolerance-related traits. …”
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Chronic health consequences of the COVID-19 pandemic on school workers: a cross-sectional post-pandemic analysis by Louise C Mâsse, Michael A Irvine, David M Goldfarb, Sheila F O’Brien, Liam Golding, Allison W Watts, Collette O’Reilly, Daniel Coombs, Mark Pitblado, Sirui Li, Pascal Lavoie

“…However, there are insufficient data on the chronic physical and mental health consequences of the pandemic in school workers.Objectives To determine the prevalence and the functional and mental health impact of pandemic-related chronic health symptoms among school workers towards the end of the COVID-19 pandemic.Design Cross-sectional analysis of health questionnaires and serology testing data (nucleocapsid, N antibodies) collected between January and April 2023, within a cohort of school workers.Setting Three large school districts (Vancouver, Richmond, Delta) in the Vancouver metropolitan area, Canada (representing 186 elementary and secondary schools in total).Participants Active school staff employed in these three school districts.Exposure COVID-19 infection history by self-reported viral and/or nucleocapsid antibody testing.Main outcomes Self-reported, new-onset pandemic-related chronic health symptoms that started within the past year, lasting at least 3 months, after a positive viral test among those with a known infection.Results Of 1128 school staff enrolled from 185/186 (99.5%) schools, 1086 (96.3%) and 998 (88.5%) staff completed health questionnaires and serology testing, respectively. …”
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Comparative analysis of clinical characteristics of symptomatic pituitary adenomas in elderly patients: a consecutive series of 114 patients by Run Wang, Xiaodi Han, Cheng Xie, Qinghua Zhang, Liang Kan, Sheng Han

“…The tumors were primarily non-functional pituitary adenomas (NFPAs, 73.7%), with a high degree of suprasellar invasion but a low degree of parasellar invasion (P<0.0001). …”
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Research hotspots and frontiers of endoplasmic reticulum in glomerular podocytes: a bibliometric and visual analysis from 2005 to 2023 by Wang Junli, Hao Zhihong, Wang Lina, Ou Qiaoqun, Qu Jing, Hu Jiaqi, Shengyou Yu, Shengyou Yu, Shengyou Yu

“…This study aims to map the existing research on podocyte endoplasmic reticulum by analyzing publications in the Web of Science Core Collection (WOSCC) from the past 19 years.MethodsWe conducted a bibliometric analysis using Citespace, VOSviewer, the Metrology Literature Online platform, and the Bibliometrix software package to visualize and interpret the data from WOSCC. …”
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Genetic diversity within Strongyloides fuelleborni: mitochondrial genome analysis reveals a clear African and Asian division by Travis Richins, Sarah G. H. Sapp, Alexandra Juhasz, Lucas J. Cunningham, E. James La Course, J. Russell Stothard, Joel L. N. Barratt

“…Whole-genome sequencing data were generated with later phylogenetic analysis of mitochondrial (mt) cytochrome oxidase subunit 1 (cox1) and nuclear ribosomal 18S sequences against 300 published Strongyloides reference genotypes. …”
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Systematic review and meta-analysis of microbiota-gut-astrocyte axis perturbation in neurodegeneration, brain injury, and mood disorders by Daniel E. Radford-Smith, Katharine Oke, Carolina F.F.A. Costa, Daniel C. Anthony

“…Future studies must adopt new, multi-dimensional studies of astrocyte function and dysfunction, to elucidate their role in disease and explore the therapeutic potential of gut microbiota modulation.…”
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Risk factors associated with the failure of day surgery for total knee arthroplasty a multivariate logistic regression analysis by Pan Luo, Jiabin Feng, Yankun Li, Yingli Zou, Xuepeng Zhu, Li Sun, Bo Li

“…ObjectiveTo explore and analyze the risk factors leading to delayed discharge in patients undergoing day surgery for total knee arthroplasty, providing a theoretical basis for optimizing patient selection, targeted interventions, and managing expectations and risks of day surgery patients.MethodsA retrospective analysis of clinical data from patients diagnosed with “knee osteoarthritis” and scheduled for day surgery for total knee arthroplasty at the Department of Orthopedics, Guizhou Provincial People's Hospital from October 2021 to June 2023. …”
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Whole-Transcriptome Sequencing and Differential Expression Analysis of the Epididymis in Junggar Bactrian Camels Before and After Sexual Maturity by Jiahao Liu, Xinkui Yao, Jun Meng, Jianwen Wang, Yaqi Zeng, Linling Li, Wanlu Ren

“…This study presents a comprehensive whole-transcriptome analysis of the epididymis in Junggar Bactrian camels before and after sexual maturity, identifying key genes and regulatory pathways associated with epididymal development and reproductive function. …”
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Effective treatment of hydroplasty injections and immediate physical therapy for glenohumeral adhesive capsulitis: a retrospective clinical analysis by Austin J. Koenig, BA, Evan P. Shoemaker, BA, Rebecca Stone McGaver, MS, ATC, Ayush D. Shah, BA, James A. Palmer, DPT, Allan F. Hunt, MD

“…Results: A total of 182 patients, for 189 shoulders, were included in the study for data analyses. Dependent, 2-tailed paired t-test analysis showed a statistically significant increase in ROM in forward flexion, abduction, internal rotation, ER at side, and ER at 90 (P value < .001). …”
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Plasma FGF2 and YAP1 as novel biomarkers for MCI in the elderly: analysis via bioinformatics and clinical study by Yejing Zhao, Yejing Zhao, Xiang Wang, Jie Zhang, Yanyan Zhao, Yi Li, Ji Shen, Ying Yuan, Jing Li

“…A total of 350 DEGs were identified in bioinformatics data mining. Functional enrichment analysis showed that fibroblast growth factor 2(FGF2) and yes-associated protein 1(YAP1) protein levels were highly expressed in AD samples, indicating their potential regulatory roles in AD. …”
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Immuno-transcriptomic analysis based on machine learning identifies immunity signature genes of chronic rhinosinusitis with nasal polyps by Zhaonan Xu, Qing Hao, Bingrui Yan, Qiuying Li, Xuan Kan, Qin Wu, Hongtian Yi, Xianji Shen, Lingmei Qu, Peng Wang, Yanan Sun

“…Our study identified a total of 660 differentially expressed genes (DEGs) and 81 differentially immune-related genes (DIRGs) in CRSwNP compared to controls. Functional enrichment analysis revealed that the DIRGs were primarily associated with cell chemotaxis and leukocyte migration, and cytokine-cytokine receptor interaction. …”
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Comparative transcriptomic and genomic analysis of tumor cells in the marginal and center regions of tumor nests in human hepatocellular carcinoma by Ziyi Li, Ziyi Li, Yikai Hu, Yikai Hu, Zhuotian He, Heyi Xu, Hongyang Wang, Hongyang Wang, Hongyang Wang, Yufei He

“…This center-margin functional division may inform rational design of therapeutics that simultaneously modulate metabolism and immune responses.…”
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Complement and coagulation cascade cross-talk in endometriosis and the potential of Janus Kinase inhibitors—a network meta-analysis by Monika Golinska, Monika Golinska, Aleksander Rycerz, Matylda Sobczak, Jedrzej Chrzanowski, Konrad Stawiski, Wojciech Fendler, Wojciech Fendler, Wojciech Fendler

“…EEM: CPA3, logFC = 1.54, p &lt; 0.0001; KIT, logFC = 0.74, p &lt; 0.001). Functional enrichment analysis highlighted complement and coagulation, inflammation, angiogenesis, and extracellular matrix remodeling as drivers of endometriosis. …”
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Do Patients with Rheumatoid Arthritis Have an (In)Adequate Level of Physical Activity? A Latent Class Analysis Approach by Sretko Lukovic, Marko Baralic, Nina Tomonjic, Jovana Mihailovic, Aleksandra Neskovic, Marina Vujovic Sestakov, Ivana Pavlovic, Branko Barac, Tatjana Zivanovic Radnic, Predrag Ostojic

“…Latent class analysis (LCA) was used to identify subpopulations of patients. …”
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Bayesian Analysis of Hybrid Neutron Star EOS Constraints Within an Instantaneous Nonlocal Chiral Quark Matter Model by Alexander Ayriyan, David Blaschke, Juan Pablo Carlomagno, Gustavo A. Contrera, Ana Gabriela Grunfeld

“…We present a physics-informed Bayesian analysis of equation of state constraints using observational data for masses, radii and tidal deformability of pulsars and a generic class of hybrid neutron star equation of state with color superconducting quark matter on the basis of a recently developed nonlocal chiral quark model. …”
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The Validation of the Nomophobia Questionnaire Using a Modern Psychometric Approach: An Item Response Theory Analysis of 5087 Participants by Haitham Jahrami, Khaled Trabelsi, Achraf Ammar, Nicola Luigi Bragazzi, Hadeel Ghazzawi, Waqar Husain, Maha M. AlRasheed, Seithikurippu R. Pandi‐Perumal, Amir Pakpour, Zahra Saif, Michael V. Vitiello

“…IRT analyses included graded response modeling of items, test information function, differential item functioning, and reliability. …”
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Polarization Analysis of Type III Langmuir/Z-mode Waves with Coherent Magnetic Component Observations by Solar Orbiter by Tomáš Formánek, Ondřej Santolík, Jan Souček, David Píša, Arnaud Zaslavsky, Matthieu Kretzschmar, Milan Maksimovic, Christopher J. Owen, Georgios Nicolaou

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Oncological results of emergency operations for right-sided colorectal cancer by Yu. S. Vayner, K. V. Atamanov, S. G. Shtofin, G. S. Shtofin, I. V. Ishutov

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