Analysis the Spatial Dynamics of Aloe Vera Medicinal Plants in Climate Change condition. Case: Hormozgan Province by Shahrbanoo Ghanbari Adivi, Morteza Khodagholi, Amir Gandomkar

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Accelerating visual field loss with age: A statistical approach using a large-scale real-world dataset by Tomoki Shirakami, Tetsuro Omura, Hiroki Fukuda, Ryo Asaoka, Masaki Tanito

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High-dimensional mediation analysis reveals the mediating role of physical activity patterns in genetic pathways leading to AD-like brain atrophy by Hanxiang Xu, Shizhuo Mu, Jingxuan Bao, Christos Davatzikos, Haochang Shou, Li Shen

“…We employed conventional summary statistics and functional principal component analysis to extract patterns of PA as mediators. …”
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Antioxidant activity analysis of new interspecific hybrid germplasm thyme and oregano essential oils with different chemotypes by Meiyu Sun, Jiahui Miao, Yanan Zhang, Yuanpeng Hao, Jinzheng Zhang, Hui Li, Hongtong Bai, Lei Shi

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Improved cohesin HiChIP protocol and bioinformatic analysis for robust detection of chromatin loops and stripes by Karolina Buka, Zofia Parteka-Tojek, Abhishek Agarwal, Michał Denkiewicz, Sevastianos Korsak, Mateusz Chiliński, Krzysztof H. Banecki, Dariusz Plewczynski

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PERSPECTIVES OF FACTORIAL ANALYSIS IN STUDYING ASSOCIATIONS BETWEEN IMMUNE SYSTEM PARAMETERS AND CLINICAL CHARACTERISTICS IN GASTRIC CANCER by I. G. Solovyeva, L. V. Shcherbakova, V. S. Kozhevnikov, V. V. Abramov, V. A. Kozlov

“…In present study, four factors are revealed, which are associated with certain clinical characteristics of gastric cancer (tumor invasion depth, lymph node status and distant metastases, tumor stage, histological type). The data obtained are of interest, with regard of systemic approach to functional studies of immune functions.…”
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Reduced TREM2 activation in microglia of patients with Alzheimer's disease by Yuumi Okuzono, Hiroyuki Sakuma, Shuuichi Miyakawa, Masataka Ifuku, Jonghun Lee, Debashree Das, Antara Banerjee, Yang Zhao, Koji Yamamoto, Tatsuya Ando, Shuji Sato

“…Differentially expressed genes (DEGs) following TREM2 activation were compared with the gene set extracted from microglial single nuclear RNA sequencing data of patients with AD, using gene set enrichment analysis. …”
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Analysis of the Upper Limit of the Stability of High and Steep Slopes Supported by a Combination of Anti-Slip Piles and Reinforced Soil Under the Seismic Effect by Wei Luo, Gequan Xiao, Zhi Tao, Jingyu Chen, Zhulong Gong, Haifeng Wang

“…The theoretical results are validated against published data, demonstrating satisfactory agreement. Finally, the MATLAB R2022a sequential quadratic programming method is used to optimize the objective function, and the Optum G2 2023 software is employed to analyze the factors influencing slope stability due to the interaction between anti-slide piles and geogrids. …”
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Mesenchymal Stem Cell Therapy for Acute Myocardial Infarction: Protocol for a Systematic Review and Meta-Analysis by Michael Vincent DiCaro, Brianna Yee, KaChon Lei, Kavita Batra, Buddhadeb Dawn

“…ResultsLiterature search and article screening commenced in June 2023. Data extraction and analysis will be completed by October 2024. …”
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Interspinous process devices for treatment of degenerative lumbar spine stenosis: A systematic review and meta-analysis. by Arthur Werner Poetscher, Andre Felix Gentil, Mario Ferretti, Mario Lenza

“…Primary and secondary outcomes were not measured in all studies and were often published in incomplete form. Subgroup analysis was not feasible. Difficulty in contacting authors may have prevented us of including data in quantitative analysis.…”
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Integrative analysis of H&E and IHC identifies prognostic immune subtypes in HPV related oropharyngeal cancer by Sumanth Reddy Nakkireddy, Inyeop Jang, Minji Kim, Linda X. Yin, Michael Rivera, Joaquin J. Garcia, Kathleen R. Bartemes, David M. Routman, Eric. J. Moore, Chadi N. Abdel-Halim, Daniel J. Ma, Kathryn M. Van Abel, Tae Hyun Hwang

“…Conclusions Integrating H&E and IHC data enhances the functional characterization of immune phenotypes of the TME with biological interpretability, and improves patient stratification in HPV( + ) OPSCC.…”
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The Perioperative Resource Use and Effectiveness of Patellofemoral Arthroplasty Versus Total Knee Arthroplasty: A Meta‐Analysis by Ziying Wu, Ning Wang, Jian Zhang, Cong Lu, Wenni Rong, Xiang Ding, Guanghua Lei

“…Regarding PROMs, PFA showed superior functional outcomes on the Oxford Knee Score (OKS) within 2 years postoperatively (MD = −2.02; 95% CI: −3.77 to −0.26). …”
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Integrated genetic analysis of Alzheimer's disease and stroke subtypes: insights from LDSC, PLACO, and MR studies by Yu Long, Jinfeng Liu, Jinniu Guo, Jinzhao Jiang, Xiangyu Wang, Ruohan Sun

“…Methods The Linkage Disequilibrium Score Regression (LDSC) for heritability and genetic correlations, Polygenic Likelihood Ratio under a Composite Null Hypothesis (PLACO) method for pleiotropic loci and locus, and Functional maps and annotations from genome-wide association studies (FUMA) for function analysis of multi-effect loci, multi-marker analysis of genoMic annotation (MAGMA) for gene tissue specificity, Mendelian Randomization (MR) analyses for causal relationships between AD and five stroke subtypes were performed through Single Nucleotide Polymorphism (SNP) heritability enrichments and causal associations were analyzed using comprehensive GWAS data. …”
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Acute gastrointestinal and post-acute COVID-19 gastrointestinal syndrome assessment on the Gastrointestinal Symptom Rating Scale scoring system: A questionnaire-based survey by Sunita Singh, Niraj K. Srivastava, Rahul Yadav, Saurabh Paul, Shefali Gupta, Sankalp, Priyanshi Dixit

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A Systematic Review of the Use of Electronic Nose and Tongue Technologies for Detecting Food Contaminants by Muhammad Zia Ul Haq, Baljit Singh, Xolile Fuku, Ahmed Barhoum, Furong Tian

“…This review examines 112 studies published from 2004 to 2025, and examines the functionalities and performance in detecting various food product-associated analytes. …”
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UFO: A tool for unifying biomedical ontology-based semantic similarity calculation, enrichment analysis and visualization. by Duc-Hau Le

“…Important applications of those data include estimating the functional similarity between ontology terms and between annotated biomedical entities, analyzing enrichment for a set of biomedical entities. …”
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Meta-analysis of targeted drugs for pulmonary hypertension to improve exercise tolerance and associated factors in eisenmenger syndrome by Zhangli Yuan, Yang Wang, Jianling Wang, Yinchuan Lai, Xuechuan Dan, Juan Wang

“…According to the heterogeneity test results, the effect model was adopted for analysis by RevMan5.4 statistical software, in which the continuity data were represented by mean difference (MD) and 95% confidence interval (CI). …”
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Training and inference Time Efficiency Assessment Framework for machine learning algorithms: A case study for hyperspectral image classification by Xiaorou Zheng, Jianxin Jia, Shoubin Dong, Yawei Wang, Runuo Lu, Yuwei Chen, Yueming Wang

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A Review of Standardization in Mississippi’s Multidecadal Inland Fisheries Monitoring Program by Caleb A. Aldridge, Michael E. Colvin

“…Standardizing data collection, management, and analysis processes can improve the reliability and efficiency of fisheries monitoring programs, yet few studies have examined the operationalization of these tasks within agency settings. …”
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Intertwined depressive and cognitive trajectories and the risk of dementia and death in older adults: a competing risk analysis by Jufen Liu, Ziyang Ren, Yushan Du, Lirong Nie

“…To date, their joint trajectories and associations with dementia and death remain underexplored.Aims To explore the interactions between depressive symptoms and cognitive function, their developmental trajectories and the associations with all-cause dementia, Alzheimer’s disease (AD) and all-cause death in older adults.Methods Data were from the Health and Retirement Study. …”
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