Extending gene set variation analysis with a reference dataset to stabilize scores by Lorin Towle-Miller, William Jordan, Alexandre Lockhart, Johannes Freudenburg, Aman Virmani, Mandy Bergquist, Jeffrey Miecznikowski, Will Powley

“…This becomes a major issue when study data does not adequately represent the full distribution of the population. …”
Get full text

Integrating single-cell RNA-Seq and bulk RNA-Seq data to explore the key role of fatty acid metabolism in hepatocellular carcinoma by Hua Dai, Xin Tao, Yuansen Shu, Fanrong Liu, Xiaoping Cheng, Xiushen Li, Bairui Shu, Hongcheng Luo, XuXiang Chen, Zhaorui Cheng

“…Further analytical procedures involved functional enrichment analysis, evaluation of immune infiltration, and examination of the mutation landscape.PTGES3 was identified as a pivotal gene associated with lipid metabolism. …”
Get full text

Text Mining for Consumers’ Sentiment Tendency and Strategies for Promoting Cross-Border E-Commerce Marketing Using Consumers’ Online Review Data by Changting Liu, Tao Chen, Qiang Pu, Ying Jin

“…In terms of changes in review sentiments, the negative proportion of the topics of functional features and usage effects is still relatively high. …”
Get full text

Costs of pharmacotherapy in pediatric patients with community-acquired pneumonia: mathematical and statistical analysis by I. A. Narkevich, O. D. Nemyatyh, D. D. Siukaeva, I. V. Pavlushkov, D. O. Ivanov, Ya. V. Panyutina

“…Dispersion analysis of qualitative factors (gender, location of pneumonic infiltrate) showed no significant impact of these factors on the costs or the number of prescribed drugs in the total data set. …”
Get full text

Predefined and data-driven CT radiomics predict recurrence-free and overall survival in patients with pulmonary metastases treated with stereotactic body radiotherapy. by Pascal Salazar, Patrick Cheung, Balaji Ganeshan, Anastasia Oikonomou

“…First-order radiomic features were extracted using two methods: 2D CT texture analysis (CTTA) using TexRAD software, and a data-driven technique: functional principal components analysis (FPCA) using segmented tumoral and peri-tumoural 3D regions.…”
Get full text

ASSESSMENT METHOD FOR INTRA-JOINT DISORDERS IN PATIENTS WITH ARTICULATION-OCCLUSIVE DISORDERS AND TMJ DYSFUNCTION BASED ON CONE-BEAM COMPUTED TOMOGRAPHY DATA by A.M. Proschenko

“…Analysis of the obtained data using Welch's test revealed a statistically significant difference (p ≤ 0.000) in comparison to the control group, based on the average values of the observed displacements. …”
Get full text

Nonlinear Dynamics Analysis of Handgrip Strength Using the Poincaré Plot Method Through Video Processing Techniques by Constantin Ciucurel, Elena Ioana Iconaru

“…Data analysis included descriptive and inferential statistics. …”
Get full text

Potential multiple disease progression pathways in female patients with Alzheimer's disease inferred from transcriptome and epigenome data of the dorsolateral prefrontal cortex. by Kousei Honda, Akinori Awazu

“…Here, based on an analysis of publicly available data from female patients, this study found that AD pathology appears to be nonuniform; AD patients were divided into several groups with differential gene expression patterns, including those related to cognitive function. …”
Get full text

CooccurrenceAffinity: An R package for computing a novel metric of affinity in co-occurrence data that corrects for pervasive errors in traditional indices. by Kumar P Mainali, Eric Slud

“…CooccurrenceAffinity is a practical and efficient R package with user-friendly functions for end-to-end analysis and plotting of co-occurrence data in various formats, making it possible to compute the recently developed metric of alpha MLE as well as its median and confidence intervals introduced in this paper. …”
Get full text

Evaluation and Analysis of Environmental Aging of Public Space in Cold Urban Settlements Based on Importance Performance Analysis Theory—Taking Urumqi as an Example by Li Zhang, Ping Yuan, Yingjie Ding

“…Based on the research data of Urumqi settlements, this study utilizes importance performance analysis to evaluate the performance and importance of the aging public space environment. …”
Get full text

Smart Buildings and Digital Twin to Monitoring the Efficiency and Wellness of Working Environments: A Case Study on IoT Integration and Data-Driven Management by Giuseppe Piras, Sofia Agostinelli, Francesco Muzi

“…In relation to emergency management, real-time data can be acquired, allowing information to be shared with users and building managers through the creation of dashboards and visual analysis. …”
Get full text

Cohort protocol: risk assessment of maternal inflammation and early brain development in infants and young children based on multi-source data modeling by Xianghui Huang, Xianghui Huang, Cuimin Su, Ying Lin, Ying Lin, Tianyi Zhou, Ruming Ye, Ruming Ye, Dan Li, Dan Li, Miaoshuang Liu, Guanhong Wu, Wanting Li, Namei Xie, Xiaofang Deng, Nanxi Zhu, Shaohong Lin, Qin Li, Kai Yan, Deyi Zhuang, Deyi Zhuang

“…Therefore, it is of great significance to evaluate the risk of maternal inflammation to early brain development in infants and young children based on multi-source data modeling to understand the mechanism of early development and prevent brain development disorders.Methods and analysisBetween December 2021 and May 2024, 360 pairs of pregnant women and their offspring were recruited into the Xiamen Children's Brain Development Cohort. …”
Get full text

Association of body mass index with disability in activities of daily living in older adults: a systematic review of the literature based on longitudinal data by Wang Lingying, Zhu Hong, Chen Hongxiu, Hu Ziyi, Feng Mei, Tang Menglin, Hu Xiuying

“…Studies were selected based on predefined inclusion and exclusion criteria, and relevant data were extracted for subsequent meta-analysis using the Cochrane Collaboration’s Review Manager 5.3 software. …”
Get full text

From prediction to practice: mitigating bias and data shift in machine-learning models for chemotherapy-induced organ dysfunction across unseen cancers by Heather Shaw, Pinkie Chambers, Matthew Watson, Luke Steventon, James Harmsworth King, Angelo Ercia, Noura Al Moubayed

“…We propose gold-standard bias mitigation steps for ML models: evaluation on multisite data, thorough patient population analysis, and both formalised bias measures and model performance comparisons on patient subgroups. …”
Get full text

Characterization of Fitness Profiles in Youth Soccer Players in Response to Playing Roles Through Principal Component Analysis by Boryi A. Becerra Patiño, Aura D. Montenegro Bonilla, Juan D. Paucar-Uribe, Diego A. Rada-Perdigón, Jorge Olivares-Arancibia, Rodrigo Yáñez-Sepúlveda, José Francisco López-Gil, José Pino-Ortega

Get full text

Automated Probabilistic System Architecture Analysis in the Multi-Attribute Prediction Language (MAPL): Iteratively Developed using Multiple Case Studies by Robert Lagerström, Pontus Johnson, Mathias Ekstedt, Ulrik Franke, Khurram Shahzad

“…MAPL features automate analysis in five non-functional areas: service cost, service availability, data accuracy, application coupling, and application size. …”
Get full text

Transcriptome profiling and co-expression network analysis of 96 Haematococcus pluvialis samples by Bin Hu, Kai Liu, Feichao Du, Hailiang Xing, Xiaoyuan Su, Tao Hu, Feng Chen, Yujie Qin, Zhaozhen Dong, Xue Sun, Liuquan Zhang, Jagroop Pandhal, Nianjun Xu, Chaoyang Hu

“…Gene functional classification analysis revealed their involvement in metabolic pathways related to genetic information processing and primary/secondary metabolite metabolism. …”
Get full text

Single-cell sequencing and transcriptomic data reveal that P65 activation significantly promotes microglia-mediated neuroinflammation after ischemic stroke by Ruiyu Wang, Yilun Qian, Xinchen Zhou, Hang Xu, Yu Wang, Yao Geng, Tianshu Wang, Binxiu Sha

“…The Seurat pipeline was employed for standard quality control and single-cell data analysis. Monocle2 and CytoTRACE were used for trajectory analysis, while Mfuzz was applied to identify time-series gene expression patterns. …”
Get full text

Application of Isokinetic Dynamometry Data in Predicting Gait Deviation Index Using Machine Learning in Stroke Patients: A Cross-Sectional Study by Xiaolei Lu, Chenye Qiao, Hujun Wang, Yingqi Li, Jingxuan Wang, Congxiao Wang, Yingpeng Wang, Shuyan Qie

“…Although isokinetic dynamometry, utilizing sophisticated sensors, is widely employed in muscle function assessment and rehabilitation, its application in gait analysis remains underexplored. …”
Get full text

Real-world data of Azvudine-induced hepatotoxicity among hospitalized COVID-19 patients in China: a retrospective case-control study by Yuanguo Xiong, Hao Xin, Cai Shi, Xianxi Guo, Ying Chen, Caifei Huang, Fuwang Ma, Ge Yang, Jian Yang

“…Receiver operating characteristic (ROC) curve analysis was performed to calculate the area under the ROC curve (AUC).ResultsIn total, 669 patients were included in the Azvudine-associated hepatotoxicity research. 47.1% patients exhibited hepatotoxicity, abnormal liver function on admission [OR: 5.55 (3.94–7.90), P < 0.001] and antithrombotic drugs [OR: 1.79 (1.27–2.54), P = 0.001] were independent predictors of Azvudine-associated hepatotoxicity, with the area under the ROC curve (AUC) was 0.756 [95% CI: 0.719–0.792, P < 0.001]. …”
Get full text