Mutual coupling of neurons in the circadian master clock: What we can learn from fruit flies by Charlotte Helfrich-Förster, Nils Reinhard

“…Circadian master clocks in the brain consist of multiple neurons that are organized into populations with different morphology, physiology, and neuromessenger content and presumably different functions. …”
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Olfactory Dysfunction as a Clinical Marker of Early Glymphatic Failure in Neurodegenerative Diseases by Gonzalo Sánchez-Benavides, Alex Iranzo, Oriol Grau-Rivera, Darly Milena Giraldo, Mariateresa Buongiorno

“…The glymphatic system is a glial-associated fluid transport system that facilitates the movement of brain fluids and removes brain waste during specific sleep stages. …”
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Role of astrocytes and microglia in hepatic encephalopathy associated with advanced chronic liver disease: lessons from animal studies by Wouter Claeys, Anja Geerts, Lien Van Hoecke, Christophe Van Steenkiste, Roosmarijn E. Vandenbroucke

“…Based on a large body of mostly in vitro evidence, ammonia-induced cellular and molecular disturbances include astrocyte swelling and oxidative stress. Microglia, the brain resident macrophages, have been linked to the translation of systemic inflammation to the brain microenvironment. …”
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A Case of Klebsiella pneumoniae infection by Xuefang Liu, Ning Yu, Huaihai Lu, Yinlong Zhao, Junyu Zhu, Ya Liu

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Injectable Hierarchical Bioactive Hydrogels with Fibroblast Growth Factor 21/Edaravone/Caffeic Acid Asynchronous Delivery for Treating Parkinson's Disease by Junpeng Xu, Peng Dai, Chen Zhang, Na Dong, Caiyan Li, Chonghui Tang, Zhihao Jin, Shih‐Ho Lin, Luyang Ye, Tianmiao Sun, Yukai Jin, Fenzan Wu, Lihua Luo, Ping Wu, Shengcun Li, Xiaokun Li, Shan‐hui Hsu, Dawei Jiang, Zhouguang Wang

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Molecular insights into glioblastoma progression: role of CHCHD2P9 in tumor heterogeneity and prognosis by Yanyu Ding, Yanyu Ding, Lizhi Xiao, Lizhi Xiao, Xiaoling Zhou, Xiaoling Zhou, Jiaxin Zhao, Jiaxin Zhao, Jianli Ke, Jianli Ke, Huabao Cai, Mengyu Zhao, Cunzhi Wang, Tianhang Yu, Zhijie Zhao, Yucai Wang, Yucai Wang, Yucai Wang, Jiyuan Ke, Jiyuan Ke

“…BackgroundGliomas are highly aggressive, life-threatening tumors with poor prognosis, and remain a leading cause of mortality among brain cancers. Although the role of mitochondrial proteins in cancer has garnered increasing attention, their specific functions in the nervous system, particularly in gliomas, remain poorly understood.MethodsWe integrated single-cell RNA sequencing with cellular assays and flow cytometry to investigate the molecular characteristics and cellular interactions within glioblastoma subpopulations during tumor progression.ResultsSingle-cell RNA sequencing revealed several differentially expressed genes (DEGs) within glioblastoma subpopulations. …”
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Spatio-temporal dynamics of sound-induced vestibular processing: insights from stereo-EEG recordings by Michele Terzaghi, Piergiorgio d'Orio, Ivana Sartori, Veronica Pelliccia, Flavia Maria Zauli, Silvia Colnaghi, Valter Rustioni, Fausto Caruana, Maria Del Vecchio, Maurizio Versino, Pietro Avanzini

“…Numerous functions rely on the activation of the vestibular system, resulting in widespread activation of cortical brain regions. …”
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Developing an explainable machine learning and fog computing-based visual rating scale for the prediction of dementia progression by Zainab H. Ali, Esraa Hassan, Shimaa Elgamal, Nora El-Rashidy

“…Abstract Recently, dementia research has primarily concentrated on using Magnetic Resonance Imaging (MRI) to develop learning models in processing and analyzing brain data. However, these models often cannot provide early detection of affected brain regions. …”
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Case Report: An Atypical Sellar Mass - Sellar Tuberculoma in a Young Patient by Arwa Moiz Jamali, Rakeshkumar Luhana

“… Background: Tuberculosis of the central nervous system is an uncommon but one of the most severe forms. …”
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mRNA level of antioxidant genes and activity of NADPH-generating enzymes in rotenone-induced parkinsonism in rats by E. D. Kryl’skii, G. A. Razuvaev, T. N. Popova, L. E. Nikhaev, A. I. Akinina

“…Along with a decrease in the content of antioxidant gene mRNA in the brain tissues, the level of α-tocopherol increased in the rats with parkinsonism, which could be the result of an imbalance in the functioning of antioxidant system.…”
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CSF proteomics reveals changes in myelin and synaptic biology after Spectris treatment by Mihály Hajós, Kiran Pandey, Annabelle C. Singer, Duc Duong, Sara Bitarafan, Monika Shpokayte, Zach Malchano, Ralph Kern, James J. Lah, Allan I. Levey, Nicholas T. Seyfried

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In-depth characterization of accessory gene regulator loci and associated virulence factors in tcdA+B+ Clostridioides difficile isolates by Mansoor Kodori, Zohreh Ghalavand, Abbas Yadegar, Gita Eslami, Masoumeh Azimirad, Mohammad Reza Zali

“…This study also provides novel phenotypic insights into tcdA+B+ C. difficile isolates from Iranian patients, paving the way for more comprehensive functional and clinical studies of agr loci.…”
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Exploration of the potential neurotransmitter or neuromodulator-like properties of harmine: evidence from synthesis to synaptic modulation by Zhejun Xie, Ning Cao, Manlin Li, Hanxue Wang, Huida Guan, Xuemei Cheng, Changhong Wang

“…The target protein was then recombinantly expressed, purified, and functionally validated. Subsequently, the release, metabolism, and uptake pathways of harmine were investigated using rat brain synaptosomes and primary neural cells through mass spectrometry analysis. …”
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Extracellular vesicles as precision therapeutics for psychiatric conditions: targeting interactions among neuronal, glial, and immune networks by Ivana Kawiková, Ivana Kawiková, Ivana Kawiková, Václav Špička, James C. K. Lai, James C. K. Lai, Philip W. Askenase, Li Wen, Zdeněk Kejík, Zdeněk Kejík, Milan Jakubek, Milan Jakubek, Karel Valeš, Karel Valeš, Filip Španiel, Filip Španiel

“…The critical role of the immune system in brain function and dysfunction is well recognized, yet development of immune therapies for psychiatric diseases has been slow due to concerns about iatrogenic immune deficiencies. …”
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A split-GAL4 driver line resource for Drosophila neuron types by Geoffrey W Meissner, Allison Vannan, Jennifer Jeter, Kari Close, Gina M DePasquale, Zachary Dorman, Kaitlyn Forster, Jaye Anne Beringer, Theresa Gibney, Joanna H Hausenfluck, Yisheng He, Kristin Henderson, Lauren Johnson, Rebecca M Johnston, Gudrun Ihrke, Nirmala A Iyer, Rachel Lazarus, Kelley Lee, Hsing-Hsi Li, Hua-Peng Liaw, Brian Melton, Scott Miller, Reeham Motaher, Alexandra Novak, Omotara Ogundeyi, Alyson Petruncio, Jacquelyn Price, Sophia Protopapas, Susana Tae, Jennifer Taylor, Rebecca Vorimo, Brianna Yarbrough, Kevin Xiankun Zeng, Christopher T Zugates, Heather Dionne, Claire Angstadt, Kelly Ashley, Amanda Cavallaro, Tam Dang, Guillermo A Gonzalez III, Karen L Hibbard, Cuizhen Huang, Jui-Chun Kao, Todd Laverty, Monti Mercer, Brenda Perez, Scarlett Rose Pitts, Danielle Ruiz, Viruthika Vallanadu, Grace Zhiyu Zheng, Cristian Goina, Hideo Otsuna, Konrad Rokicki, Robert R Svirskas, Han SJ Cheong, Michael-John Dolan, Erica Ehrhardt, Kai Feng, Basel EI Galfi, Jens Goldammer, Stephen J Huston, Nan Hu, Masayoshi Ito, Claire McKellar, Ryo Minegishi, Shigehiro Namiki, Aljoscha Nern, Catherine E Schretter, Gabriella R Sterne, Lalanti Venkatasubramanian, Kaiyu Wang, Tanya Wolff, Ming Wu, Reed George, Oz Malkesman, Yoshinori Aso, Gwyneth M Card, Barry J Dickson, Wyatt Korff, Kei Ito, James W Truman, Marta Zlatic, Gerald M Rubin, FlyLight Project Team

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Machine learning model for reproducing subjective sensations and alleviating sound-induced stress in individuals with developmental disorders by Itsuki Ichikawa, Yukie Nagai, Yukie Nagai, Yasuo Kuniyoshi, Yasuo Kuniyoshi, Yasuo Kuniyoshi, Makoto Wada

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An interaction-centric approach for quantifying eye-to-eye reciprocal interaction by Ray Lee, Paul Sajda, Nim Tottenham

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Immune conversations at the border: meningeal immunity in health and disease by Preya U. Patel, Preya U. Patel, Aryan Regmi, Aryan Regmi, Angelina I. Dass, Angelina I. Dass, Olga L. Rojas, Olga L. Rojas

“…The brain and spinal cord, collectively known as the central nervous system, are encapsulated by an overlapping series of membranes known as the meninges. …”
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CD8 T cell dynamics and immune cell trafficking in ZIKV infection: implications for neuroinflammation and therapy by Sungjun Park

“…This review explores the dual roles of CD8 T cells during ZIKV infection, emphasizing both their antiviral functions and their potential to drive neuroinflammation. …”
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Predicting imitative performance through cortico-cerebellar circuits: A multivariate and effective connectivity study by Antonino Errante, Giuseppe Ciullo, Settimio Ziccarelli, Alessandro Piras, Cristina Russo, Leonardo Fogassi

“…The present study aimed at investigating whether functional interaction between cortical areas and the cerebellum during the observation of complex bimanual actions can predict individual ability to imitate the same actions. …”
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