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Using Heart Rate Variability Monitoring for Dexmedetomidine Dosing in Neurointensive Care Patients
Published 2021-02-01“…Electrophysiological neuromonitoring of the autonomic nervous system function increases the efficacy of dexmedetomidine administration in patients with brain injury of various etiologies.…”
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1802
Morphology and ultrastructure of external sense organs of Drosophila larvae
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1803
Understanding Cognitive Decline in Aging: Mechanisms and Mitigation Strategies – A Narrative Review
Published 2025-04-01“…Declining cognitive function is associated with changes in the central nervous system per se or peripheral triggers that impair cognition. …”
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Cholinergic neurotransmission in the anterior cingulate cortex is associated with cognitive performance in healthy older adults: Baseline characteristics of the Improving Neurologi...
Published 2025-03-01“…These findings suggest that [18F]FEOBV PET imaging can be used as a reliable biomarker to assess cholinergic changes in the human brain and indicate that preserving the cholinergic integrity of the basal forebrain may help maintain cognitive function and protect against age-related cognitive decline.…”
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Deletion of Metabotropic Glutamate Receptors 2 and 3 (mGlu2 & mGlu3) in Mice Disrupts Sleep and Wheel-Running Activity, and Increases the Sensitivity of the Circadian System to...
Published 2015-01-01“…The co-morbidity of schizophrenia and SCRD may in part stem from dysfunction in common brain mechanisms, which include the glutamate system, and in particular, the group II metabotropic glutamate receptors mGlu2 and mGlu3 (encoded by the genes Grm2 and Grm3). …”
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Assessment of the glymphatic dysfunction in amyotrophic lateral sclerosis using the diffusion tensor imaging along the perivascular spaces index: a pilot study
Published 2025-05-01“…BackgroundThe glymphatic system plays a critical role in clearing interstitial waste from the brain. …”
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1810
The Toxic Truth: How Alcohol Harms the Body from Head to Toe
Published 2025-06-01“…This literature review aims to explore the extensive and often underappreciated harmful effects of alcohol on the human body, spanning from the brain to the musculoskeletal system. Through a comprehensive examination of current research, we delve into alcohol’s neurotoxic effects, its contribution to cardiovascular and hepatic diseases, and its disruptive impact on endocrine and immune functions. …”
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Loss of Bmal1 impairs the glutamatergic light input to the SCN in mice
Published 2025-02-01“…IntroductionGlutamate represents the dominant neurotransmitter that conveys the light information to the brain, including the suprachiasmatic nucleus (SCN), the central pacemaker for the circadian system. …”
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Analysis of ALPS‐Index: Difference in Type 2 Diabetes Mellitus With or Without Mild Cognitive Impairment and Its Relationship With Hippocampal Microstructure
Published 2025-07-01“…Conclusion In summary, our findings demonstrated that glymphatic system function in the brain progressively deteriorates with worsening cognitive impairment among T2DM patients. …”
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Prenatal Alcohol Exposure and Transient Systemic Hypoxia–Ischemia Result in Subtle Alterations in Dendritic Complexity in Medial Frontal Cortical Neurons in Juvenile and Young Adul...
Published 2024-11-01“…Prenatal alcohol exposure (PAE) is associated with long-term neurodevelopmental deficits resulting in impaired executive functioning and motor control. Intriguingly, PAE has been linked with an increased risk of transient systemic hypoxia–ischemia (TSHI), which alone results in suboptimal fetal growth and neurodevelopmental consequences. …”
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Therapeutic Efficacy of Small Extracellular Vesicles Loaded with ROCK Inhibitor in Parkinson’s Disease
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Computer Simulation of Cardiomyocyte Membrane Exposure to First<Phase Bipolar Defibrillation Impulses
Published 2014-06-01“…The injected drugs were ascertained to have a positive effect on functional recovery of the brain. Their use was shown to modify the sex steroid hormone profiles in both males and females in the early postresuscitation period.Conclusion. …”
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Microglia: Mediators of experience-driven corrective neuroplasticity
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A New Era of Muscarinic Acetylcholine Receptor Modulators in Neurological Diseases, Cancer and Drug Abuse
Published 2025-03-01“…The cholinergic pathways in the central nervous system (CNS) play a pivotal role in different cognitive functions of the brain, such as memory and learning. …”
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Oral Hygiene and Cardiovascular Health
Published 2025-04-01“…<i>Porphyromonas gingivalis</i> and <i>Fusobacterium nucleatum</i> drive chronic inflammation in periodontal disease; these bacteria can extend beyond the mouth and contribute to systemic inflammatory responses. The inflammatory factors, including C-reactive protein (CRP), interleukins (IL-1, IL-6), and tumor necrosis factor-alpha (TNF-α), damage blood vessels, impair endothelial functions, and promote atherosclerosis, all key events in CVD progression. …”
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Generation of Neural Organoids and Their Application in Disease Modeling and Regenerative Medicine
Published 2025-08-01“…The advent of organoid technology derived from stem cells has addressed many of these limitations, providing highly representative platforms for studying the structure and function of the human embryonic brain and spinal cord. …”
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