A Case Report and Literature Review of Primary Central Nervous System Lymphoma in a Patient with Crigler–Najjar Syndrome: How We Managed by Udip Maheshwari, Disha Morzaria, Seema Jagiasi, Vashishth Maniar, Ashish Joshi, Sameer Soneji

“…Primary central nervous system lymphoma (PCNSL) is a rare form of CNS tumor that can be managed with curative intent using high-dose chemotherapeutic drugs. …”
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Feasibility of Observing Glymphatic System Activity During Sleep Using Diffusion Tensor Imaging Analysis Along the Perivascular Space (DTI-ALPS) Index by Chang-Soo Yun, Chul-Ho Sohn, Jehyeong Yeon, Kun-Jin Chung, Byong-Ji Min, Chang-Ho Yun, Bong Soo Han

“…<b>Background/Objectives</b>: The glymphatic system plays a crucial role in clearing brain metabolic waste, and its dysfunction has been correlated to various neurological disorders. …”
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Clinical effectiveness of exogenous L-arginine in patients with coronary heart disease after community-acquired pneumonia by T. O. Kulynych

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Impact of Enteric Nervous Cells on Irritable Bowel Syndrome: Potential Treatment Options by Ploutarchos Pastras, Ioanna Aggeletopoulou, Christos Triantos

“…Given the limited therapeutic options currently available, it is essential to identify new treatment targets, with the brain-gut axis, particularly the enteric nervous system, being a promising focus. …”
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Small extracellular vesicles and particles (sEVPs) derived from tumor-free pre-metastatic organs promote breast cancer metastasis and support organotropism by Tasneem Cheytan, Martin Schneider, Roberto Würth, Paul Schwerd-Kleine, Ewgenija Gutjahr, Verena Thewes, Laura L. Michel, Rebecca Weber, Tim Vorberg, Sabrina Lohr, Katja Nitschke, Michelle Neßling, Peter Lichter, Andreas Schneeweiss, Karsten Richter, Dominic Helm, Martin Sprick, Andreas Trumpp

“…Here, we characterized and studied the function of sEVPs secreted from tumor-free pre-metastatic organs (TuFMO-sEVPs) such as the brain and lungs in both immunocompetent and patient-derived xenograft models. …”
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Destructive Effects of Pyroptosis on Homeostasis of Neuron Survival Associated with the Dysfunctional BBB-Glymphatic System and Amyloid-Beta Accumulation after Cerebral Ischemia/Re... by Zhongkuan Lyu, Yuanjin Chan, Qiyue Li, Qiang Zhang, Kaili Liu, Jun Xiang, Xiangting Li, Dingfang Cai, Yaming Li, Bing Wang, Zhonghai Yu

“…However, whether pyroptosis acts as a trigger of Aβ accumulation after cerebral I/R has not yet been demonstrated. Blood-brain barrier (BBB) and glymphatic system mediated by aquaporin-4 (AQP-4) on astrocytic endfeet are important pathways for the clearance of Aβ in the brain, and pyroptosis especially occurring in astrocytes after cerebral I/R potentially damages BBB integrity and glymphatic function and thus influences Aβ clearance and brain homeostasis. …”
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Electrical stimulation of the dorsolateral prefrontal cortex inhibits vestibular signalling in humans: A BOLD fMRI study by Brendan McCarthy, Donggyu Rim, Gianni Sesa-Ashton, Lewis S. Crawford, Tye Dawood, Luke A. Henderson, Vaughan G. Macefield

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BDNF/Cyclin D1 Signaling System and Cognitive Performance After Perampanel and Lacosamide Treatment Singly or in Combination in an Experimental Model of Temporal Lobe Epilepsy by Michaela Shishmanova-Doseva, Darina Barbutska

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The light chains of microtubule-associated proteins MAP1A and MAP1B interact with α1-syntrophin in the central and peripheral nervous system. by Heike Fuhrmann-Stroissnigg, Rainer Noiges, Luise Descovich, Irmgard Fischer, Douglas E Albrecht, Fatiha Nothias, Stanley C Froehner, Friedrich Propst

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Attachment, Shame, and Trauma by Carol George

“…Background/Objectives: Early parent–child attachment interactions guided by right-to-right brain synchrony are the foundation of emotional development and the quality of attachment relationships. …”
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Clinical Presentations and Treatment Approaches in a Retrospective Analysis of 128 Intracranial Arteriovenous Malformation Cases by Corneliu Toader, Mugurel Petrinel Radoi, Milena-Monica Ilie, Razvan-Adrian Covache-Busuioc, Vlad Buica, Luca-Andrei Glavan, Christian-Adelin Covlea, Antonio Daniel Corlatescu, Horia-Petre Costin, Carla Crivoi, Leon Danaila

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Role of Lysophosphatidic Acid in Neurological Diseases: From Pathophysiology to Therapeutic Implications by Simona Dedoni, Valeria Avdoshina, Maria C. Olianas, Pierluigi Onali

“…Lysophosphatidic acid (LPA), a bioactive lipid molecule, has been identified as a critical regulator of several cellular processes in the central nervous system, with significant impacts on neuronal function, synaptic plasticity, and neuroinflammatory responses. …”
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Optimization of neuron-specific interfering peptides targeting GABAB receptor downregulation for proteolytic stability for conferring neuroprotection in a mouse model of cerebral i... by Mohammad Hleihil, Musadiq A. Bhat, Thomas Grampp, Dietmar Benke, Dietmar Benke

“…BackgroundCerebral ischemia triggers a cascade of detrimental events, leading to brain damage mainly due to the over-excitation of neurons. …”
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Enhancing Drug Discovery and Development through the Integration of Medicinal Chemistry, Chemical Biology, and Academia-Industry Partnerships: Insights from Roche’s Endocannabinoid... by Johannes Aebi, Kenneth Atz, Simon M. Ametamey, Jörg Benz, Julie Blaising, Stefania Butini, Giuseppe Campiani, Erick M. Carreira, Ludovic Collin, Eva de Lago, Thais Gazzi, Jürg Gertsch, Luca Gobbi, Wolfgang Guba, Javier Fernández-Ruiz, Jürgen Fingerle, Achi Haider, Yingfang He, Laura H. Heitman, Michael Honer, Daniel Hunziker, Bernd Kuhn, Mauro Maccarrone, Hans Peter Märki, Rainer E. Martin, Peter Mohr, Linjing Mu, Marc Nazaré, David F. Nippa, Sergio Oddi, Fionn O’Hara, Pal Pacher, Julian Romero, Stephan Röver, Arne C. Rufer, Roger Schibli, Gisbert Schneider, Antonia F. Stepan, David A. Sykes, Christoph Ullmer, Mario van der Stelt, Dmitry B. Veprintsev, Matthias B. Wittwer, Uwe Grether

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Reactive astrocyte-derived exosomes enhance intracranial lymphatic drainage in mice after intracranial hemorrhage by Kexin Li, Yuheng Liu, Junjie Gong, Jing Li, Mingyu Zhao, Chengyou Hong, Yuchi Zhang, Mengyao He, Zhenye Zhu, Zhijuan Chen, Zengguang Wang

“…Our study focuses on the effects of hemin-treated reactive astrocyte-derived exosomes on the functional integrity of the glymphatic system (GLS) after ICH and their potential mechanism of action in repairing brain injury. …”
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The RELN heterozygous single-nucleotide polymorphism rs362691 increases the prefrontal cortical thickness and modulates systemizing-related autistic tendencies in typically develop... by Hiroki Sato, Hiroki Sato, Hiroki Sato, Mitsunari Abe, Mitsunari Abe, Hikaru Takeuchi, Hiroaki Tomita, Shigeo Kure, Shigeo Kure, Ryuta Kawashima, Yasuyuki Taki

“…These findings suggest that while the rs362691 variant does not significantly influence autism-related cognitive styles per se, it may alter cortical morphology in prefrontal regions functionally linked to systemizing traits in typically developing individuals. …”
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Neural mechanism of dopamine modulating singing related behavior in songbirds: an updated review by Linghua Zhong, Weiting Li, Mengjiao Liu, Wei Sun, Zhibin Liu, Songhua Wang

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Effectiveness of 4 weeks of electrical vestibular stimulation in the management of temporomandibular pain by Yashica Gowda R, Asha G, Doreswamy Kanakaiah, Karthik N, Sai Sailesh Kumar Goothy, Mukkadan JK

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Estrogen, menopause, and Alzheimer’s disease: understanding the link to cognitive decline in women by Nicholas Mervosh, Gayatri Devi, Gayatri Devi, Gayatri Devi

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Clinical and pathogenesis interpretation of changes in the electrocardiogram in infectious diseases by Yu. P. Finogeev, S. M. Zacharenko, A. V. Semena

“…The basis of circulatory disorders is a common factor in central nervous system (brain) as the most sensitive to the action of an infectious toxin. …”
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