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Suggested Topics within your search.
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1721
Selective Auditory Attention Detection Using Combined Transformer and Convolutional Graph Neural Networks
Published 2024-11-01“…The findings of this study have important implications for the understanding and assessment of auditory attention, which is crucial for many applications, such as brain–computer interface (BCI) systems, speech separation, and neuro-steered hearing aid development.…”
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1722
Sleep and Risk of Multiple Sclerosis: Bridging the Gap Between Inflammation and Neurodegeneration via Glymphatic Failure
Published 2025-07-01“…Epidemiological studies identified insufficient and poor-quality sleep as independent risk factors for multiple sclerosis (MS). The glymphatic system, active during slow-wave sleep, clears brain waste through perivascular astrocytic aquaporin-4 (AQP4) channels. …”
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1723
The neurohormone tyramine stimulates the secretion of an insulin-like peptide from the Caenorhabditis elegans intestine to modulate the systemic stress response.
Published 2025-01-01“…However, the release dynamics and specific functions of these ILPs in adapting to different environmental conditions remain poorly understood. …”
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1724
A software system for modeling evolution in a population of organisms with vision, interacting with each other in 3D simulator
Published 2023-01-01“…For a system of hundreds or thousands of neurons, one can still hope to determine the necessary parameters and get the functioning of the nervous system more or less similar to that of a living organism – as, for example, in a recent work on the modeling of the Xenopus tadpole. …”
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1725
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1726
Can thermoregulatory response to heat stress be improved in lactating dairy cows? Insights from counter-current heat transfer systems impacting reproduction
Published 2025-01-01“…Physiological counter-current heat transfer mechanisms maintaining brain/hypothalamic and reproductive functions in cattle are vulnerable to HS. …”
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1727
Stilbenes Against Alzheimer’s Disease: A Comprehensive Review of Preclinical Studies of Natural and Synthetic Compounds Combined with the Contributions of Developed Nanodrug Delive...
Published 2025-04-01“…AD is a worldwide neurodegenerative disease characterized by the destruction of nerve cells in the brain and the loss of cognitive function due to aging. …”
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1728
Are Glucagon-Like Peptide-1 (GLP-1) Receptor Agonists Central Nervous System (CNS) Penetrant: A Narrative Review
Published 2025-04-01“…Replicated evidence suggests that CNS penetration of GLP-1 RAs can be proxied by reported effects of GLP-1 RAs on brain connectivity in human participants. Conclusion Preclinical studies indicate that select GLP-1 RAs are CNS penetrant; whether GLP-1 RAs reproducibly engage neural targets hypothesized to subserve dimensions of psychopathology (e.g., general cognitive functions) remains incompletely characterized.…”
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1729
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1730
Delineating Life‐Course Percentile Curves and Normative Values of Multi‐Systemic Ageing Metrics in the United Kingdom, the United States, and China
Published 2025-06-01“…ABSTRACT Background Ageing is a complex and multi‐dimensional process that manifests heterogeneities across different organs/systems, individuals and countries. We aimed to delineate the life‐course percentile curves and establish the normative values of multi‐systemic (e.g., muscle‐skeletal, brain, cardiovascular and pulmonary) ageing metrics for people under distinct sociodemographic contexts (i.e., sex, income and education). …”
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1731
Public Administration Transformation Based on Research in Social Neurosciences in the Context of Sustainable Development. (Part 1)
Published 2022-06-01“…There is a need to revise public administration, and this will require a special programme of research on the relationship between the patterns of thinking, the neurobiological response of the brain and social problems, which will help to determine the parameters of the organization of society in which the human brain and mind will function optimally. …”
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1733
Prototype of a Multimodal and Multichannel Electro-Physiological and General-Purpose Signal Capture System: Evaluation in Sleep-Research-like Scenario
Published 2025-04-01“…The simultaneous analysis of electrophysiological signals from various physiological systems, such as the brain, skeletal muscles, and cardiac muscles, has become increasingly necessary in both clinical and research settings. …”
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Exploring subthreshold processing for next-generation TinyAI
Published 2025-07-01“…We propose pathways such as algorithmic analogs of subthreshold integration, including graded activation functions, dendritic-inspired hierarchical processing, and hybrid analog-digital systems to emulate the energy-efficient operations of biological neurons. …”
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1736
A 3D human iPSC-derived multi-cell type neurosphere system to model cellular responses to chronic amyloidosis
Published 2025-04-01“…Microglia are not only neuroprotective in neurospheres but also act as key drivers of Aβ-dependent APOE expression suggesting critical roles for microglia in regulating APOE in the AD brain. This novel, well characterized, functional in vitro platform offers unique opportunities to study the roles and responses of microglia to Aβ modelling key aspects of human AD. …”
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1737
Microglial intervention in ischemic stroke: Roles and intervention strategies
Published 2026-02-01“…Microglia exhibit a dynamic functional state, transitioning between pro-inflammatory (M1) and anti-inflammatory (M2) phenotypes. …”
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1738
A single systemic inflammatory insult causes acute motor deficits and accelerates disease progression in a mouse model of human tauopathy
Published 2019-01-01“…Discussion This is the first demonstration that a single systemic inflammatory episode causes exaggerated acute functional impairments and accelerates the long‐term trajectory of functional decline associated with neurodegeneration in a mouse model of human tauopathy. …”
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1739
Long-term systemic androgen deprivation partially modulates neuroinflammation in male App NL−G−F/NL−G−F mice
Published 2025-04-01“…In castrated App mice, microglial Tnf and Il6 and astrocytic Socs3 were downregulated, indicating that androgens may promote inflammation in the brain. However, Aβ accumulation and cognitive function were unaffected. …”
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1740
Crosstalk between miRNAs, high mobility group box-1 and complement system in epilepsy: relevance of response to valproic acid
Published 2025-08-01“…Abstract Background Epileptogenesis is a complex alteration of brain functions with subsequent development of seizures. …”
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