Infiltration Pattern of Blood Monocytes into the Central Nervous System during Experimental Herpes Simplex Virus Encephalitis. by Rafik Menasria, Coraline Canivet, Jocelyne Piret, Guy Boivin

“…The lack of albumin detection in the brain parenchyma of infected mice showed that the infiltration of blood leukocytes was not necessarily related to a breakdown of the blood-brain barrier but could be the result of a functional recruitment. …”
Get full text

Cerebellar microglia: On the edge between neuroinflammation and neuroregulation by Marina S. Dukhinova, Jingwen Guo, Enwei Shen, Wanting Liu, Wanqi Huang, Ying Shen, Luxi Wang

Get full text

Unveiling the potential of Lactobacillus johnsonii in digestive diseases: a comprehensive review by Jinjie Zhou, Jinjie Zhou, Jinjie Zhou, Shuang Ma, Shuang Ma, Shuang Ma, Zhuo Huang, Zhuo Huang, Zhuo Huang, Qinyan Yao, Qinyan Yao, Qinyan Yao, Zihan Yu, Zihan Yu, Zihan Yu, Jihua Chen, Jihua Chen, Jihua Chen, Liuqing Yao, Liuqing Yao, Liuqing Yao, Lanping Zhu, Lanping Zhu, Lanping Zhu, Xin Chen, Xin Chen, Xin Chen

“…These findings further validate the important role of this strain in maintaining intestinal microbiota homeostasis, regulating body metabolism, and brain-gut axis function.ConclusionIn summary, L. johnsonii shows great promise in digestive health by modulating immunity, enhancing the gut barrier and balancing gut microbiota. …”
Get full text

Resting State of Dementia of the Alzheimer’s Type and Healthy Older Adults Using fNIRS by In-sop Kim, Jaejin Hwang, Chorong Oh, Richard J. Morris

Get full text

Downregulation of the NPY-Y1R system in Grpr neurons results in mechanical and chemical hyperknesis in chronic itch by Danqing Dai, Zongxi Li, Tiantian Zhao, Zhen Li, Yali Tang, Xiujuan Li, Xiao-Fei Gao, Lize Xiong

Get full text

Exercise-induced anxiety impairs local and systemic inflammatory response and glucose metabolism in C57BL/6J mice by I. Gálvez, M.C. Navarro, S. Torres-Piles, L. Martín-Cordero, M.D. Hinchado, E. Ortega

Get full text

Modulation of the central nervous system immune response and neuroinflammation via Wnt signaling in health and neurodegenerative diseases by Kevin Fang

“…Wnt signaling is a crucial pathway in the CNS that regulates various cellular processes critical for brain development, function, and maintenance. Despite enhancing immune responses in the health CNS, dysregulated Wnt signaling exacerbates neuroinflammation in the neurodegenerative brains. …”
Get full text

Relationship Between Cognitive Impairment and Quality of Life in Systemic Lupus Erythematosus: A Multimodal Neuroimaging Perspective by Liu Q, Liu M, Zou Q

“…Multimodal MRI techniques offer valuable insights into structural, functional, and metabolic abnormalities across both localized brain regions and global neural networks, facilitating comprehensive assessment of SLE-related cognitive dysfunction. …”
Get full text

A Gaussian Mixture Model-Based Unsupervised Dendritic Artificial Visual System for Motion Direction Detection by Zhiyu Qiu, Yuxiao Hua, Tianqi Chen, Yuki Todo, Zheng Tang, Delai Qiu, Chunping Chu

Get full text

Eye signs as a novel risk predictor in pulmonary arterial hypertension associated with systemic lupus erythematosus by Jianbin Li, Jiangbiao Xiong, Pengcheng Liu, Yilin Peng, Shuang Cai, Xia Fang, Shujiao Yu, Jun Zhao, Rui Wu

“…The evaluation of various parameters, such as N-terminal prohormone of brain natriuretic peptide (NT-proBNP), 6-minute walking distance (6MWD), World Health Organization functional class (WHO-FC), echocardiography, and risk stratification based on the 2015 European Society of Cardiology (ESC)/European Respiratory Society (ERS) Guidelines, was conducted at intervals of every 1–3 months, and a 6-month follow-up period was observed. …”
Get full text

Deep Learning-Enhanced Motor Training: A Hybrid VR and Exoskeleton System for Cognitive–Motor Rehabilitation by Kathya P. Acuña Luna, Edgar Rafael Hernandez-Rios, Victor Valencia, Carlos Trenado, Christian Peñaloza

“…The project showcased an optimized system designed to assess and train cognitive–motor functions in elderly individuals. …”
Get full text

Feasibility of in vivo small animal imaging using a clinical total-body PET/CT system by Julia G. Mannheim, Wenhong Lan, Maurizio Conti, Franziska Siedler, Marcel A. Krueger, Kristina Herfert, Christian la Fougère, Fabian P. Schmidt

“…SUVmean and SUVmax values were determined for liver, muscle and brain regions on both systems. To evaluate potential position-dependent effects within the extended axial FOV, a single frozen mouse was scanned at multiple positions. …”
Get full text

Healing through faith: Meeting a chaplain coupled with biblical readings could produce lymphocyte changes that correlate with brain activity (HEALING study) [version 5; peer review... by András Béres, Csaba Aranyi, Miklós Emri, Éva Perpékné Papp, Edit Hörcsik, Márta Kuti, Ferenc Tomanek, Ferenc Nagy, Dániel Fajtai, Pál Bödecs, Péter Szabó, Eszter Vinczen, Bettina Bakos, Renáta Sillinger, Eszter Gál, Hajnalka Kisdeákné, Ágnes Petőfalviné, Dániel Kovács, Gergely Bíró, Tamás Németh, Judit Fodor, Imre Repa, Erzsébet Papp, Antal Szilágyi, Zoltán Szalai, György Nagyéri, Marianna Kiss-Merki

“…Background Faith and belief systems impact the emotional as well as immunological states of believers in ways that we are just beginning to understand. …”
Get full text

A Scoping Review on Cognition in Myelodysplastic Syndromes: Advances and Challenges by Anna Tsiakiri, Konstantinos Frigkas, Pinelopi Vlotinou, Menelaos Papoutselis, Foteini Christidi, Efstratios Karavasilis, Ioannis Kotsianidis, Nikolaos Kourkoutsakis, Konstantinos Vadikolias, Konstantinos Liapis

Get full text

Role of the amygdala opioid system in the effects of stress on the post-learning sleep patterns of male Wistar rats by Mehdi Graily-Afra, Farideh Bahrami, Zahra Bahari, Hedayat Sahraei, Zeinab Shankayi, Ali Gharib

“…Through naloxone injection in the Baso Lateral Amygdala (BLA), this study intends to shed light on the interactions between stress, learning, and sleep, as well as the function of the opioid system and its impact on Brain-Derived Neurotrophic Factor (BDNF) production in the hippocampus.Materials and Methods: Male Wistar rats (n=77) in eleven groups were implanted with electroencephalogram (EEG) and electromyography (EMG) recording electrodes, and the BLA area was bilaterally cannulated. …”
Get full text

The Possibilities of Single-Pill Combinations of Antihypertensive Drugs in Cerebroprotection: Focus on the Combination of Amlodipine with Ramipril by A. I. Kochetkov, S. V. Batyukina, O. D. Ostroumova, M. Yu. Nazranova, V. N. Butorov

“…Acute cerebrovascular events have many risk factors, among them the most important is arterial hypertension (AH), which predisposes to the stroke development through the direct effect of increased hydrostatic blood pressure on the brain vascular system, followed by arterial remodeling and an increase in their stiffness. …”
Get full text

Systemic Primary Carnitine Deficiency Presenting With Substantia Nigra and Basal Ganglia Injury: A Case Report by Tomoki Saito, Kento Soma, Mai Kashisaka, Kiiko Iketani, Masaaki Matsumoto, Takuya Ueda, Masahiro Nishiyama, Azusa Maruyama, Ryosuke Nakai, Hiroshi Sakihama, Hiroshi Kurosawa, Naoya Morisada, Hironori Kobayashi, Kayo Ozaki

“…L‐DOPA was initiated on day 62, resulting in improvements in dystonia, swallowing, and motor function. By day 88, MRI showed resolution of basal ganglia abnormalities, though cerebral atrophy persisted. …”
Get full text

Global collaboration and innovation in malignant cerebral edema research: a bibliometric perspective by Xinhua Peng, Xinhua Peng, Rongrong Zhu, Ke Zhang, Jianghong Ji, Chuanguo Lv, Feng Feng, Feng Feng

“…AimMalignant cerebral edema (MCE) is a life-threatening complication of acute brain injuries, with mortality rates exceeding 80% in the absence of treatment. …”
Get full text

Nanomaterials in the treatment of degenerative intellectual and developmental disabilities by Humaira Aslam, Ali Umar, Nazia Nusrat, Manel Mansour, Aman Ullah, Shehla Honey, Muhammad Jehanzeb Sohail, Mustansar Abbas, Muhammad Waseem Aslam, Misbah Ullah Khan

“…Due to their size, surface characteristics, and ability to be functionalized, these carriers can directly deliver therapeutics across what is considered one of the main barriers to central nervous system (CNS) treatment, the blood-brain barrier (BBB). …”
Get full text

Cloning of claudin-5 Gene from Oreochromis niloticus and Analysis of Its Expression Under Streptococcus agalactiae by Yanghui CHEN, Suying ZHANG, Yongxiong HUANG, Zirui ZHANG, Bei WANG

“…After stimulated by S. agalactiae, claudin-5 of O. niloticus played an important role in the host's resistance to S. agalactiae invasion, especially in protecting the central nervous system through the blood-brain barrier.…”
Get full text