The glymphatic system as a therapeutic target: TMS-induced modulation in older adults by Mark H. Sundman, Yilin Liu, Nan-kuei Chen, Ying-hui Chou, Ying-hui Chou

“…DTI-ALPS is an MRI-based measure that reflects the efficiency of the brain’s glymphatic waste removal system, as it quantifies how easily water molecules move along the perivascular spaces where waste is cleared. …”
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Simultaneous EEG-fNIRS Data Classification Through Selective Channel Representation and Spectrogram Imaging by Chayut Bunterngchit, Jiaxing Wang, Zeng-Guang Hou

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Mosquito- and tick-borne orthoflaviviruses cross an in vitro endothelial-astrocyte barrier by Felix Schweitzer, Felix Schweitzer, Lara-Jasmin Schröder, Lara-Jasmin Schröder, Alina Friedrichs, Alina Friedrichs, Viktoria Gudi, Thomas Skripuletz, Imke Steffen, Imke Steffen, Martin Palus, Martin Palus, Daniel Růžek, Daniel Růžek, Daniel Růžek, Albert Osterhaus, Albert Osterhaus, Chittappen Kandiyil Prajeeth

“…These viruses have developed mechanisms to breach the compact blood-brain barrier (BBB) and establish infection within the central nervous system (CNS). …”
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Dexmedetomidine and the glymphatic system: a new perspective in managing postoperative cognitive dysfunction by Sha-Sha Zhang, Fan-Geng Meng, Yuan-Yuan Rong, Yi-Wen Zhang, Hua-Qin Liu

“…This review provides a comprehensive summary of how Dex modulates glymphatic system function, with a particular focus on its potential to prevent POCD through mechanisms such as promoting CSF flow, restoring AQP4 polarity, and attenuating neuroinflammation. …”
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Quantitative analysis of the change in neuronal numerical density of the human nucleus dentatus within development by Gudović Radmila, Marić Dušica L., Krstonošić Bojana, Babović Siniša S., Ristanović Dušan, Milošević Nebojša T.

“…To better understand functions and relations of the dentate nucleus it is highly important to study its development process. …”
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The translational power of Alzheimer’s-based organoid models in personalized medicine: an integrated biological and digital approach embodying patient clinical history by Cristina Dolciotti, Marco Righi, Eleonora Grecu, Marcello Trucas, Cristina Maxia, Daniela Murtas, Andrea Diana

“…BOs derived from patient-specific induced pluripotent stem cells (iPSCs) mimic the structural and functional complexities of the human brain. This advancement offers an alternative or complementary approach for studying AD pathology, including β-amyloid and tau protein aggregation, neuroinflammation, and aging processes. …”
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Collagen mimetic peptides as novel therapeutics for vascular disease in the central nervous system by Olivia L. Bossardet, Joseph M. Holden, Brian J. Del Buono, Eric Schlumpf, Lauren K. Wareham, David J. Calkins

“…Collagens within the ECM and vascular basement membrane are integral to endothelial cell (EC) function and maintenance of the blood-brain barrier. …”
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Parent brain responses to child facial and vocal communication: What different methodologies reveal about parenting cognitions and practices as well as their moderation by parental... by Marc H. Bornstein, Amir Gandjbakhche, Thien Nguyen, Gianluca Esposito

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Renin-angiotensin system as an emerging target to modulate adult neurogenesis in health and disease by Jannette Rodríguez-Pallares, Lucia A. Garcia-Crivaro, Juan A. Parga, Jose Luis Labandeira-Garcia

“…In addition to the circulating RAS, a local brain RAS has been described, with a key role in brain homeostasis. …”
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MeCP2 prevents against sustained ketamine-induced synaptic depression at inhibitory synapses by Michelle K. Piazza, Abigael R. Weit, Ege T. Kavalali, Jeffrey L. Neul, Lisa M. Monteggia

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Research progress on the role and mechanisms of microglia in inflammatory diseases of central nervous system by YU Kai, SHUAI Zhewei, HUANG Hongjun, LUO Yan

“…Microglia are the resident immune cells in the central nervous system (CNS), and play a dual role in maintaining brain homeostasis and mediating neuroprotection. …”
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Intestinal barrier damage caused by addictive substance use disorder by Yan Gao, Deshenyue Kong, Jia-xue Sun, Zhong-xu Ma, Guang-qing Wang, Xing-feng Ma, Liang Sun, Hua-you Luo, Yu Xu, Kun-hua Wang

“…Gut barrier damage leads to dysbiosis, which in turn affects brain function by activating immune cells and releasing inflammatory factors. …”
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Human neural organoid microphysiological systems show the building blocks necessary for basic learning and memory by Dowlette-Mary Alam El Din, Leah Moenkemoeller, Alon Loeffler, Forough Habibollahi, Jack Schenkman, Amitav Mitra, Tjitse van der Molen, Lixuan Ding, Jason Laird, Maren Schenke, Erik C. Johnson, Brett J. Kagan, Thomas Hartung, Lena Smirnova

“…Abstract Brain Microphysiological Systems, including neural organoids derived from human induced pluripotent stem cells, offer a unique lens to study the intricate workings of the human brain. …”
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The arrow of time in Parkinson’s disease by Fatemeh Sadeghi, Elvira del Agua Banyeres, Alessandra Pizzuti, Abdullah Okar, Kai Grimm, Christian Gerloff, Morten L. Kringelbach, Rainer Goebel, Simone Zittel, Gustavo Deco

“…Background: Parkinson’s disease (PD) is a system-level disorder that implicates brain network dynamics across multiple scales. …”
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Developmental trajectory of Caenorhabditis elegans nervous system governs its structural organization. by Anand Pathak, Nivedita Chatterjee, Sitabhra Sinha

“…A central problem of neuroscience involves uncovering the principles governing the organization of nervous systems which ensure robustness in brain development. …”
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Human iPSC for Therapeutic Approaches to the Nervous System: Present and Future Applications by Maria Giuseppina Cefalo, Andrea Carai, Evelina Miele, Agnese Po, Elisabetta Ferretti, Angela Mastronuzzi, Isabelle M. Germano

“…Many central nervous system (CNS) diseases including stroke, spinal cord injury (SCI), and brain tumors are a significant cause of worldwide morbidity/mortality and yet do not have satisfying treatments. …”
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Research Progress on the Correlation Between Microecological Flora and Endometriosis by LI Maoping, CHANG Heng

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Auditory Brainstem Response Findings in Children with Level 1 Autism Spectrum Disorder: A Comparative Study by Mariana de Medeiros Cardoso, Rudimar dos Santos Riesgo, Pricila Sleifer

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Glucose metabolism impairment in major depressive disorder by Fanhao Meng, Jing Wang, Long Wang, Wei Zou

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Lipid-based nanoparticles for drug delivery in Parkinson’s disease by Cai Han, Liu Dong, Xue Wei-Wei, Ma Liya, Xie Hai-Tao, Ning Ke

“…The effective delivery of pharmacological agents to the central nervous system is hindered by various factors, including the restrictive properties of the blood‒brain barrier and blood‒spinal cord barrier, as well as the physicochemical characteristics of the drugs. …”
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