Early brain gene network alterations and growth disruptions in juvenile Chinese longsnout catfish (Leiocassis longirostris) induced by 17β-estradiol and 17α-methyltestosterone by Yang Feng, Hua Ye, Yongqiang Deng, Zhongmeng Zhao, Han Zhao, Senyue Liu, Lu Zhang, Yuanliang Duan, Zhipeng Huang, Jun Du, Qiang Li, Jian Zhou, Chengyan Mou

“…Growth inhibition was observed in both treatment groups, with E2β-induced reductions in body weight exceeding those of MT. Functional enrichment analysis linked these transcriptional changes to disrupted pathways in synaptic signaling, chromatin remodeling, and endocrine regulation. …”
Get full text

Shengui Sansheng San alleviates the worsening of blood–brain barrier integrity resulted from delayed tPA administration through VIP/VIPR1 pathway by Jiacheng Hu, Yiyang Li, Xingping Quan, Yan Han, Jinfen Chen, Mengchen Yuan, Ying Chen, Manfei Zhou, Enze Yu, Jiahao Zhou, Dawei Wang, Ruibing Wang, Yonghua Zhao

“…Conclusion SSS alleviates the worsening of BBB integrity resulted from delayed tPA administration, reduces hemorrhagic transformation and infarction volume, and ameliorates brain blood flow and neurological function in AIS mice. …”
Get full text

Non-invasive visualisation of long-lasting brain metabolic alterations in murine pseudo-infection model using parahydrogen-polarised [1-13C] pyruvate MRI by Hayate Tomiyama, Masaki Yamasaki, Takayuki Isagawa, Norihiko Takeda, Takuya Hashimoto, Hiroshi Hirata, Shingo Matsumoto

Get full text

Effects of aging on nitrergic system in human basal nuclei by Bruno Lopes dos Santos

“…To investigate the distribution and morphology of the nitrergic system in human basal nuclei, we studied samples from the striatum, globus pallidus, subthalamic nucleus, substantia nigra and pedunculopontine nucleus of 20 human brains from subjects without neurologic/psychiatric diseases. …”
Get full text

Comparison of differences in transcriptional and genetic profiles between intra-central nervous system and extra-central nervous system large B-cell lymphoma by Shu Wang, Hong Chen, Bo Dai, Kang Zheng, Jiajun Zheng, Yuqi Zhu, Yan Yuan, Tianling Ding, Qian Wang, Liqian Xie, Rui Feng, Fengping Zhu, Jianbin Xiang, Weiqun Ding, Hong Ding, Yuan Li, Xiaodong Gu, Kunpeng Wu, Yifan Yuan, Jianping Song, Dongxiao Zhuang, Haoshu Zhong, Hanfeng Wu, Ying Mao, Tong Chen

Get full text

Statistical analysis of the formation mechanism of concepts-representations in organizational and technical systems by Alexander A. Solodov

“…In accordance with the ideas of cognitive theory in the human brain, images (schemes, categories, gestalts, systems, archetypes, etc.) are formed and then are processed. …”
Get full text

Revisiting human language and speech production network: A meta-analytic connectivity modeling study by Chun-Wei Hsu, Chu-Chung Huang, Chih-Chin Heather Hsu, Yanchao Bi, Ovid Jyh-Lang Tzeng, Ching-Po Lin

Get full text

Compensatory adaptation of parallel motor pathways promotes skilled forelimb recovery after spinal cord injury by Imran S. Sheikh, Kathleen M. Keefe, Noelle A. Sterling, Ian P. Junker, Chen Li, Jie Chen, Xiao-Ming Xu, Lynn G. Kirby, George M. Smith

Get full text

Exploring the diversity of biological processes regulated by glial cell line-derived neurotrophic factor, a pleiotropic molecule with therapeutic potential by Cristina Porcari, Cristina Porcari, Stefano Cattaneo, Lucia Crippa, Michele Simonato, Michele Simonato, Barbara Bettegazzi, Barbara Bettegazzi

“…Glial cell line–derived neurotrophic factor (GDNF) is a potent trophic factor essential for neuronal survival and function. Encoded by the GDNF gene, its mature protein arises from specific post-translational modifications and is secreted through distinct isoform-dependent pathways. …”
Get full text

Increase in circulating GLP-1 following low FODMAP diet in irritable bowel syndrome patients by Umael Khan, Ingeborg Brønstad, Ingeborg Brønstad, Eline Margrete Randulff Hillestad, Eline Margrete Randulff Hillestad, Elisabeth K. Steinsvik, Elisabeth K. Steinsvik, Elisabeth K. Steinsvik, Trygve Hausken, Trygve Hausken, Trygve Hausken, Birgitte Berentsen, Birgitte Berentsen, Gülen Arslan Lied, Gülen Arslan Lied, Gülen Arslan Lied

Get full text

Gut microbiota remodeling exacerbates neuroinflammation and cognitive dysfunction via the microbiota-gut-brain axis in prenatal VPA-exposed C57BL/6 mice offspring by Zhaoming Liu, Zhaoming Liu, Caixia Wu, Caixia Wu, Zhaojian Sun, Zuoxian Lin, Yirong Sun, Nouman Amjad, Muhammad Majid, Rajesh Basnet, Zhiyuan Li, Zhiyuan Li, Zhiyuan Li

“…Co-occurrence networks highlighted disrupted microbial interactions, while functional profiling indicated impaired carbohydrate metabolism and elevated neurotoxic pathway activity.DiscussionPrenatal VPA exposure induces gut microbiota remodeling that exacerbates neuroinflammation and cognitive dysfunction via the microbiota-gut-brain axis. …”
Get full text

Changes in EEG Microstate Dynamics and Cognition Post‐Chemotherapy in People With Breast Cancer by S. Damji, S. Sattari, K. Zadravec, K. L. Campbell, J. Brunet, N. Virji‐Babul

“…Conclusions We observed self‐reported cognitive impairment and disturbed functional dynamics in the RS brain following chemotherapy. …”
Get full text

Reliability of multi-site UK Biobank MRI brain phenotypes for the assessment of neuropsychiatric complications of SARS-CoV-2 infection: The COVID-CNS travelling heads study. by Eugene Duff, Fernando Zelaya, Fidel Alfaro Almagro, Karla L Miller, Naomi Martin, Thomas E Nichols, Bernd Taschler, Ludovica Griffanti, Christoph Arthofer, Gwenaëlle Douaud, Chaoyue Wang, Thomas W Okell, Richard A I Bethlehem, Klaus Eickel, Matthias Günther, David K Menon, Guy Williams, Bethany Facer, David J Lythgoe, Flavio Dell'Acqua, Greta K Wood, Steven C R Williams, Gavin Houston, Simon S Keller, Catherine Holden, Monika Hartmann, Lily George, Gerome Breen, Benedict D Michael, Peter Jezzard, Stephen M Smith, Edward T Bullmore, COVID-CNS Consortium

“…Here we describe the development of such a protocol, based upon the UK Biobank, and its validation with a travelling heads study. A multi-modal brain MRI protocol comprising sequences for T1-weighted MRI, T2-FLAIR, diffusion MRI (dMRI), resting-state functional MRI (fMRI), susceptibility-weighted imaging (swMRI), and arterial spin labelling (ASL), was defined in close approximation to prior UK Biobank (UKB) and C-MORE protocols for Siemens 3T systems. …”
Get full text

Effects of Feather-Pecking Phenotype on Physiological and Neurobiological Characteristics and Gut Microbiota Profile of Goslings by Mingfeng Wang, Yujiao Guo, Zhengfeng Cao, Qi Xu, Guohong Chen, Yang Chen

Get full text

Targeting gut microbiota as a therapeutic approach for neurodegenerative diseases by Tobiloba S. Olajide, Omamuyovwi M. Ijomone

“…Abstract Recent evidence suggests a more important role of the gut microbiota in neurodegenerative diseases (NDDs) given its relationship through the microbiota‐gut‐brain as an active communication system aiding in maintaining homeostasis between the brain and the gut. …”
Get full text

Decreased gut microbiome-derived indole-3-propionic acid mediates the exacerbation of myocardial ischemia/reperfusion injury following depression via the brain-gut-heart axis by Xingdou Mu, Lele Feng, Qiang Wang, Hong Li, Haitao Zhou, Wei Yi, Yang Sun

Get full text

The Use of Antioxidants for Cardiovascular Protection in Fetal Growth Restriction: A Systematic Review by Charmaine R. Rock, Suzanne L. Miller, Beth J. Allison

Get full text

Dynamic electroencephalographic study of persons – mild COVID-19 convalescents by S. A. Gulyaev

“…In the study, a relatively new diagnostic technique for studying cognitive impairments based on the analysis of electroencephalographic microstates was implemented, which made it possible to identify signs of functional restructuring of the neuronal macronetworks of the brain and trace the characteristic adaptation of a person during the period of convalescence.…”
Get full text

Neural tuning instantiates prior expectations in the human visual system by William J. Harrison, Paul M. Bays, Reuben Rideaux

“…We further show that the adopted encoding scheme effectively embeds an environmental prior for natural image statistics within the sensory measurement, providing the functional architecture necessary for optimal inference in the earliest stages of cortical processing.…”
Get full text

The role of gut microbiota‐derived metabolites in neuroinflammation by Lingjie Mu, Yijie Wang

Get full text