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Caveolae-Mediated Transcytosis and Its Role in Neurological Disorders
Published 2025-03-01“…The blood–brain barrier (BBB) controls the flow of substances to maintain a homeostatic environment in the brain, which is highly regulated and crucial for the normal function of the central nervous system (CNS). …”
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CircSpna2 attenuates cuproptosis by mediating ubiquitin ligase Keap1 to regulate the Nrf2‐Atp7b signalling axis in depression after traumatic brain injury in a mouse model
Published 2024-11-01“…Abstract Background Depression is a common but often overlooked consequence in individuals with post‐traumatic brain injury (TBI). Circular RNAs (circRNAs) play essential roles in the nervous system, yet their involvement in the cell death mechanism known as cuproptosis and in TBI‐related depression remains unclear. …”
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TUMORAL AND NON TUMORAL PITUITARY LESIONS AND REPRODUCTIVE SYSTEM
Published 2012-05-01“…Activity of reproductive system is under the hypothalamic and hypophysial control, defining role in development and normal functioning of gonads is played by impulsive secretion of GnRH and gonadotropins. …”
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Comparative assessment of the effectiveness of modern neuroprotectors in conditions of experimental chronic cerebral ischemia
Published 2015-04-01“…Obtained results showed citicoline, cortexin and tiocetam ability to positively influence on the molecular-biochemical changes in the brain cortex with ischemia. This resulted in the glutathione-dependent enzymes activity increase, recover of the thiol-disulfide system balance, nitrotyrosine concentration decrease, improvement of the cognitive function in the experimental animals.…”
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The lateral habenula contributes to regulation of body temperature
Published 2025-07-01Get full text
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Synergies from a distance: Inspirations from the struggles of Dr James M Krueger
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Crocin nano-chitosan-coated compound mitigates hippocampal blood-brain barrier disruption, anxiety, and cognitive deficits in chronic immobilization stress-induced rats
Published 2024-10-01“…Stressful conditions can disrupt the central nervous system's normal homeostasis and physiological functions, resulting in blood-brain barrier malfunction, memory and learning impairment, anxiety, etc. …”
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Synergistic modulation of gut microbiota and mindfulness-based interventions in schizophrenia: Integrating neurotransmitter regulation and multimodal therapeutic strategies
Published 2025-05-01“…Probiotics and prebiotics are shown to rebalance the gut microbiota, thereby enhancing the synthesis of key neurotransmitters—such as serotonin, gamma-aminobutyric acid (GABA), and dopamine—and reducing systemic inflammation and oxidative stress. In parallel, MBIs, including Mindfulness-Based Stress Reduction (MBSR) and Mindfulness-Based Cognitive Therapy (MBCT), promote improvements in emotional regulation, cognitive function, and neuroplasticity through the modulation of neurophysiological pathways, notably by attenuating amygdala reactivity and heightening prefrontal cortex engagement. …”
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EXERCISE AND NEUROGENESIS
Published 2021-04-01“…During physical activities, the most affected brain region is the hippocampus. Aerobic exercises have been found to significantly increase the size and function of the human hippocampus, especially when performed with moderate exercise; it is important to ensure that the exercise is not stressful. …”
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Dynamical patterns of EEG connectivity unveil Parkinson’s disease progression: insights from machine learning analysis
Published 2025-01-01“…Functional connectivity matrices were constructed using multiple metrics, including coherence, Pearson, Spearman, canonical correlation, and Ledoit–Wolf shrinkage. …”
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Behavioral moderators of In-utero superstorm sandy exposure and fronto-limbic cortical development—potential role of adaptiveness in clinical intervention strategies, a pilot study...
Published 2025-07-01“…While no behavioral phenotype mediated the association of exposure with brain volume, adaptive behaviors, as measured by four subdomains of the BASC-2 (social skills, activities in daily life, functional communication, and adaptivity), moderated the adverse impact of in-utero stress on brain volume later in life. …”
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Males and females respond differently to treatment during isolated kidney perfusion: combined effects of glucocorticoid and estradiol
Published 2025-05-01“…BackgroundKidney perfusion is a tool that allows organs to be assessed before transplantation. After brain death (BD), hormonal dysfunction can compromise graft quality. …”
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Endocannabinoid System and Synaptic Plasticity: Implications for Emotional Responses
Published 2007-01-01“…Endocannabinoids have emerged as mediators of short- and long- term synaptic plasticity in diverse brain structures. Despite the fact that most of the studies on this field have been performed using in vitro models, endocannabinoid-mediated plasticity might be considered as a plausible candidate underlying some of the diverse physiological functions of the endogenous cannabinoid system, including developmental, affective and cognitive processes. …”
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Zebrafish as a model system for studying reproductive diseases
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The regulation of glutamatergic nervous system in sleep-wake states and general anesthesia
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Neuroimaging studies of acupuncture for depressive disorder: a systematic review of published papers from 2014 to 2024
Published 2025-05-01“…These networks are predominantly localized within various brain regions, including the default mode network, limbic system, emotion regulation and cognitive network, reward network, central executive network, salience network, and sensorimotor network. …”
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Immune System Perspective in Intracerebral Hemorrhage Research: A Focus on Monocytes and Macrophages
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Perioperative Neuroprotection with Systemic Hypothermia During Carotid Endarterectomy
Published 2025-02-01“…Prevention of brain injury during carotid endarterectomy (CEA) remains a significant challenge. …”
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