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Cerebral systems in the pathogenesis of endogenous psychoses
Published 1999-12-01“…Their neurophysiological representatives are brain systems of areas and pathways (Figs 1-4). Under functional and/or organic disturbances these systems originate the leading mental symptoms (Table 2) characterizing the diverse endogenous psychoses: hence, the latter's distinctive patterns. …”
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1262
Cerebral systems in the pathogenesis of endogenous psychoses
Published 1962-12-01“…Their neurophysiological representatives are brain systems of areas and pathways (Fig. 1-4). Under functional and/or organic disturbances these systems originate the leading mental symptoms (Table II) characterizing the diverse endogenous psychoses: hence, the latter's distinctive patterns. …”
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1263
Design considerations for optogenetic applications of soft micro-LED-based device systems across diverse nervous systems
Published 2025-06-01“…Integration of recent advancements in devices with μ-LEDs (e.g. wireless systems, optofluidic systems, multifunctionality, and closed-loop systems) enhances behavioral experiments and deepens understanding of complex neural functions in the brain, spinal cord, autonomic nervous system, and somatic nervous system. …”
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1264
A systems approach to prion disease
Published 2009-03-01“…DEGs were mapped into functional pathways and networks reflecting defined neuropathological events and PrPSc replication and accumulation, enabling the identification of novel modules and modules that may be involved in genetic effects on incubation time and in prion strain specificity. …”
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Pleiotropic vasoprotective effects of high-dose atorvastatin therapy in the context of achieving the target low-density lipoprotein cholesterol in patients after myocardial infarct...
Published 2022-08-01“…The results demonstrate the importance of achieving target LDL-C for the most favorable dynamics of brain natriuretic peptide, structural and functional characteristics of the arterial system.…”
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Precision Psychobiotics for Gut–Brain Axis Health: Advancing the Discovery Pipelines to Deliver Mechanistic Pathways and Proven Health Efficacy
Published 2025-01-01“…This missing information on both sides of the therapeutic equation when treating central nervous system (CNS) conditions makes psychobiotic research challenging, especially when compared to other pharmaceutical or functional food approaches. …”
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1268
Histaminergic Mechanisms for Modulation of Memory Systems
Published 2011-01-01“…The histaminergic system is one of the major modulatory systems, and it regulates basic homeostatic and higher functions including arousal, circadian, and feeding rhythms, and cognition. …”
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New Approach to Improving the Prognosis of Ischemic Stroke by Regulating SCFAs with Acupuncture-Rehabilitation Therapy Based on Gut-Brain Axis
Published 2023-02-01“…It can reduce the amount of some opportunistic pathogens such as <italic>Clostridium</italic>, optimize the structure of intestinal flora, and reduce the expression of key inflammatory factors and tumor necrosis factors involved in central nervous system and autoimmune diseases. In conclusion, from the perspective of gut-brain communication, the mechanism of acupuncture rehabilitation therapy in regulating the intestinal function of patients to reduce the sequelae of stroke is probably related to the metabolism of short-chain fatty acids.…”
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Neural Stem Cells in Drosophila: Molecular Genetic Mechanisms Underlying Normal Neural Proliferation and Abnormal Brain Tumor Formation
Published 2012-01-01“…Neural stem cells in Drosophila are currently one of the best model systems for understanding stem cell biology during normal development and during abnormal development of stem cell-derived brain tumors. …”
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CNS resident macrophages exhibit region-specific states and immunogenic responses during Rbpj-deficient brain arteriovenous malformation
Published 2025-01-01“…Abstract Microglia are heterogeneous macrophage cells that serve as the central nervous system’s resident immune cells. During neuro-related diseases, CNS resident macrophages change their molecular, cellular, and functional properties—that collectively define “states”—in response to specific neural perturbations. …”
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Decoding basic emotional states through integration of an fNIRS-based brain-computer interface with supervised learning algorithms.
Published 2025-01-01“…Within this advancing field, the aim of this study was to test the feasibility of a functional near-infrared spectroscopy (fNIRS)-based BCI system for accurate prediction and objective identification of three fundamental emotional states that involved positive, negative and neutral conditions. …”
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Brain tumors induce immunoregulatory dendritic cells in draining lymph nodes that can be targeted by OX40 agonist treatment
Published 2025-05-01“…Background Primary and metastatic brain tumors have a poor prognosis, partly owing to the unique characteristics of the central nervous system (CNS) and tumor immune microenvironment (TIME). …”
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Aging‐Driven Blood–Brain Barrier Dysfunction and Its Impact on CNS Cancer Susceptibility: A Comprehensive Narrative Review
Published 2025-06-01“…ABSTRACT Background Aging significantly affects the structural and functional integrity of the blood–brain barrier (BBB), increasing the susceptibility of the central nervous system (CNS) to both primary and metastatic cancers. …”
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Selective Mapping of Brain COX-1 with [11C]PS13: Pharmacokinetic Evidence from human PET Imaging
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Associations between moderate alcohol consumption, brain iron, and cognition in UK Biobank participants: Observational and mendelian randomization analyses.
Published 2022-07-01“…Potential pathways to alcohol-related iron brain accumulation through elevated systemic iron stores (liver) were explored in causal mediation analysis. …”
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Utility of a commercial antibody against NTRK1 for western blotting and potential application to immunohistochemistry in adult mouse brain
Published 2025-02-01“…Abstract Ntrk1 (also known as TrkA) is a nerve growth factor receptor with essential roles in the development and function of the cholinergic nervous system. Ntrk1 is expressed in a few specific and defined brain areas. …”
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Synchrotron Radiation X-Ray Phase-Contrast Tomography Visualizes Microvasculature Changes in Mice Brains after Ischemic Injury
Published 2016-01-01“…The CT imaging system was developed and optimized to obtain 3D brain vasculature of adult male C57BL/6 mice. …”
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