Simultaneous monitoring of the human brain, spinal cord, and cauda equina activity for movement control: An fNIRS approach by Hojeong Kim

“…Here, we present a novel optical method based on functional near-infrared spectroscopy that enables simultaneous tracking of human brain-spinal cord-cauda equina hemodynamics during body movement. …”
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Neurophysiological Markers of Reward Processing Can Inform Preclinical Neurorehabilitation Approaches for Cognitive Impairments Following Brain Injury by Miranda Francoeur Koloski, Reyana Menon, Victoria Krasnyanskiy

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WAND: A multi-modal dataset integrating advanced MRI, MEG, and TMS for multi-scale brain analysis by Carolyn B. McNabb, Ian D. Driver, Vanessa Hyde, Garin Hughes, Hannah L. Chandler, Hannah Thomas, Christopher Allen, Eirini Messaritaki, Carl J. Hodgetts, Craig Hedge, Maria Engel, Sophie F. Standen, Emma L. Morgan, Elena Stylianopoulou, Svetla Manolova, Lucie Reed, Matthew Ploszajski, Mark Drakesmith, Michael Germuska, Alexander D. Shaw, Lars Mueller, Holly Rossiter, Christopher W. Davies-Jenkins, Tom Lancaster, C. John Evans, David Owen, Gavin Perry, Slawomir Kusmia, Emily Lambe, Adam M. Partridge, Allison Cooper, Peter Hobden, Hanzhang Lu, Kim S. Graham, Andrew D. Lawrence, Richard G. Wise, James T. R. Walters, Petroc Sumner, Krish D. Singh, Derek K. Jones

“…Data are organised using the Brain Imaging Data Structure (BIDS). In addition to raw data, we provide brain-extracted T1-weighted images, and quality reports for diffusion, T1- and T2-weighted structural data, and blood-oxygen level dependent functional tasks. …”
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Non-Invasive Brain Stimulation and Artificial Intelligence in Communication Neuroprosthetics: A Bidirectional Approach for Speech and Hearing Impairments by Thorsten Rudroff

“…The integration of transcranial direct current stimulation (tDCS) and transcranial alternating current stimulation (tACS) with advanced AI algorithms enables the personalized, adaptive enhancement of neural signals for both speaking and listening functions. This paper examines current evidence for NIBS efficacy in communication disorders, explores AI innovations in neural signal processing, and discusses implementation considerations for closed-loop systems. …”
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The Influence of CYP2B6 Variants and Administration of Propofol on Patient Outcomes after Traumatic Brain Injury by Katherine O’Meara, Ava M. Puccio, Dianxu Ren, Sandra Deslouches, Ruchira Jha, David O. Okonkwo, Yvette P. Conley

“…Management of severe traumatic brain injury (sTBI) typically involves the use of sedation, which inherently results in benefits and risks. …”
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The significance of melatonin as one of the signaling substrates in the expression of psychopathological disorders in the late period after traumatic brain injury by M. O. Ovcharenko, Ye. Yu. Verbytskyi, T. M. Radchenko, V. Ye. Kazakov, I. O. Chumakova

“…Aim. To discuss the functional properties of melatonin which plays a key role in the expression of psychopathological disorders following traumatic brain injury (TBI). …”
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Effects of aerobic training and following detraining on continuous attention and brain-derived neurotrophic factor in sedentary girl students by Asiyeh Dehghani, Ehsan Zareian, Khosro Ebrahim

“…Purpose : Studies show that exercise has positive effects on the central nervous system and cognition. The brain-derived neurotrophic factor (BDNF) is an important factor affecting cognitive function and has been recently discussed in a bulk trend of efforts in the health context. …”
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MicroRNA-155 modulates methotrexate-induced spatial memory impairment by disruption of the blood-brain barrier integrity by Yu-Chieh Chen, Li-Tung Huang, Hong-Ren Yu, Jiunn-Ming Sheen

“…The aim of the study was to evaluate the role of miR-155 in the pathogenesis of MTX-induced cognitive impairment, mainly focused on the interplay of blood-brain barrier (BBB) integrity and MTX toxicity. Main methods: We use young rat model mimicking children leukemia treatment protocol, focusing on the systemic MTX effect on the central nervous system by intraperitoneal (IP) MTX injection. …”
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The diagnostic value of brain natriuretic peptide in men with comorbid essential arterial hypertension and type 2 diabetes mellitus by Ya. O. Antoniuk, A. F. Humeniuk, Yu. P. Pashkova, O. O. Sakovych, V. M. Zhebel

“…We examined 211 men. 79 people without signs of cardiovascular disease were assigned to a control group. 62 patients with EH 2 and CHF no higher than NYHA functional class (FC) I were included in the 1st, and 70 men with EH 2 combined with T2DM and CHF FC I–II formed the 2nd main study group. …”
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Association of raloxifene and tamoxifen therapy with cognitive performance, odds of mild cognitive impairment, and brain MRI markers of neurodegeneration by Firat Kara, Christine M. Lohse, Anna M. Castillo, Nirubol Tosakulwong, Timothy G. Lesnick, Clifford R. Jack Jr, Ronald C. Petersen, Janet E. Olson, Fergus J. Couch, Kathryn J. Ruddy, Kejal Kantarci, Michelle M. Mielke

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Expression Profiles of lncRNAs and mRNAs in the Mouse Brain Infected with Pseudorabies Virus: A Bioinformatic Analysis by Yanwei Li, Teng Tu, Yan Luo, Xueping Yao, Zexiao Yang, Yin Wang

“…Despite extensive research on the neuropathogenesis of α-herpesvirus infections, many scientific questions remain unresolved, such as the largely unknown functions of long non-coding RNAs (lncRNAs) in herpesvirus-infected nervous systems. …”
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Lentiviral CRISPRa/i in the adult prairie vole brain: modulating neuronal gene expression without DNA cleavage by Meredith K. Loth, Kendall T. Mesch, Celine Herrera-Garcia, Liza E. Brusman, Zoe R. Donaldson, Zoe R. Donaldson

“…Here, we present a lentivirus-mediated CRISPR activation and interference (CRISPRa/i) platform for somatic gene modulation in the prairie vole brain. This system enables non-mutagenic, titratable regulation of gene expression in the adult brain without germline modification. …”
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Androgens alleviate the depression-like phenotype in female mice by inhibiting AVPR1a in the hippocampal brain region by Shimin Ren, Xian Wang, Xueying Huang, Liyang Chen, Bing Zhang, Yang Li, Xin Huang

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Increased Brain Iron Deposition in the Putamen in Patients with Type 2 Diabetes Mellitus Detected by Quantitative Susceptibility Mapping by Jing Li, Qihao Zhang, Nan Zhang, Lingfei Guo

“…The insulin-resistant state causes iron overload in neurons and leads to lesions in the central nervous system. Quantitative susceptibility mapping (QSM) can provide a noninvasive quantitative analysis of brain iron deposition. …”
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Exploring neuropharmacokinetics: mechanisms, models, and clinical implications by Seon-Jae Ahn

“…Neuropharmacokinetics is an emerging field dedicated to understanding the pharmacokinetics of drugs within the central nervous system (CNS), with a particular emphasis on overcoming the challenges posed by the blood-brain barrier. …”
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Nose-to-brain delivery of targeted lipid nanoparticles as two-pronged β-amyloid nanoscavenger for Alzheimer's disease therapy by Yanyan Xu, Xiangtong Ye, Yanfeng Du, Wenqin Yang, Fan Tong, Wei Li, Qianqian Huang, Yongke Chen, Hanmei Li, Huile Gao, Weiwei Zhang

“…Upon intranasal administration, Lf-functionalization enabled superior brain-targeting efficacy through receptor-mediated transcytosis. …”
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Clinical and pathophysiological foundations and advanced developments in the rehabilitation of patients after ischemic stroke by E. G. Demianovskaia, A. S. Vasiliev

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NLRP3 activation induces BBB disruption and neutrophil infiltration via CXCR2 signaling in the mouse brain by Jaeho Lee, Wooyoung Cho, Je-Wook Yu, Young-Min Hyun

“…Abstract NLRP3 is an intracellular sensor molecule that affects neutrophil functionality and infiltration in brain disorders such as experimental autoimmune encephalomyelitis (EAE). …”
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Astaxanthin Mitigates ADHD Symptoms in Spontaneously Hypertensive Rats via Dopaminergic Modulation and Brain–Gut Axis Regulation by Yueyang Leng, Ning Wu, Jing Wang, Lihua Geng, Yang Yue, Quanbin Zhang

“…Attention Deficit Hyperactivity Disorder (ADHD) is a prevalent neurodevelopmental disorder that significantly impacts learning, daily functioning, and personal development. Astaxanthin (ASTA), a naturally occurring antioxidant, has garnered interest as a potential therapeutic agent for various diseases, particularly in mitigating oxidative stress. …”
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The Swimming Performance and Transcriptomic Insights Into Diverse Gene Regulation in Grass Carp Brain Under Water Velocity Stress by Mian Adnan Kakakhel, Nishita Narwal, Alam Khan, Majid Rasta, Liming Liu, Ihsan Ali, Yujiao Wu, Shi Xiaotao

“…Grass carp were subjected to controlled water velocities to measure the critical swimming speed (Ucrit), which showed that the swimming performance was increased based on body length; however, a reduction in swimming performance was observed as the water flow increased (p < 0.05). Additionally, brain samples were collected for transcriptomic analysis, which revealed that differentially expressed genes (DEGs) were functionally annotated revealing key pathways associated with changed behavior patterns. …”
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