Acupuncture modulates the microbiota-gut-brain axis: a new strategy for Parkinson’s disease treatment by Zimo Zang, Fang Yang, Liang Qu, Minghui Ge, Liang Tong, Lihui Xue, Xiuye Sun, Ying Hai

“…Acupuncture may affect the gut-brain axis and treat PD by improving intestinal flora imbalance, interfering with the expression of alpha-synuclein protecting neurological function, reducing imflammation, and influencing glial cells, etc. …”
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Relationship between Brain Natriuretic Peptide and Thromboembolic Events in Elderly Patients with Nonvalvular Atrial Fibrillation by Hongxia Wang, Jiajun Huang, Wenxi Gu, Xiaojiao Hao, Guiru Li, Yumin Yuan, Yingmin Lu

“…To investigate the relationship between brain natriuretic peptide (BNP) and thromboembolic events in elderly patients with nonvalvular atrial fibrillation (NVAF). …”
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Intravenous Nanoemulsions Loaded with Phospholipid Complex of a Novel Pyrazoloquinolinone Ligand for Enhanced Brain Delivery by Tijana Stanković, Tanja Ilić, Branka Divović Matović, Milos Petkovic, Vladimir Dobričić, Ivan Jančić, Biljana Bufan, Kristina Jezdić, Jelena Đoković, Ivana Pantelić, Danijela Randjelović, Dishary Sharmin, James M. Cook, Miroslav M. Savić, Snežana Savić

“…The quantification of CW-02-79 in plasma/brain homogenate and calculated pharmacokinetic parameters confirmed good systemic and brain availability after intravenous administration. …”
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The endocannabinoidome–gut microbiome–brain axis as a novel therapeutic target for autism spectrum disorder by Antonella Campanale, Dario Siniscalco, Vincenzo Di Marzo

“…Research highlights the roles of the endocannabinoidome (eCBome) and gut microbiome (GM), both crucial for brain and gut function. This review summarizes research on therapeutic targets within the eCBome–GM–brain axis for ASD and related comorbidities. …”
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Electron-beam FLASH whole brain irradiation induced a unique changes of intestinal flora by Feifei Gao, Wei Cheng, Yanxi Ma, Boyi Yu, Xinle Lang, Xiaodong Jin, Jianxin Wang, Xianhong Liu, Cuixia Di, Hui Wang, Fei Ye, Ting Zhao, Weiqiang Chen, Qiang Li

“…Results eFLASH irradiation significantly reduced radiation neurotoxicity and had a long-term protective effect on cognitive function and learning and memory ability. Compared with conventional irradiation, eFLASH irradiation not only up-regulated the expression of genes related to neuronal regeneration and digestive system, but also induced more abundant intestinal microflora, especially the “probiotics” such as Lachnospiraceae and others, which were proved to play a role in radiation protection, increased significantly after eFLASH irradiation. …”
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Microbial Influences on Amyotrophic Lateral Sclerosis: The Gut–Brain Axis and Therapeutic Potential of Microbiota Modulation by Victòria Ayala, Laia Fontdevila, Santiago Rico-Rios, Mònica Povedano, Pol Andrés-Benito, Pascual Torres, José C. E. Serrano, Reinald Pamplona, Manuel Portero-Otin

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Personalized whole-brain activity patterns predict human corticospinal tract activation in real-time by Uttara U. Khatri, Kristen Pulliam, Muskan Manesiya, Melanie Vieyra Cortez, José del R. Millán, Sara J. Hussain

“…These findings represent a pivotal step towards using personalized brain state-dependent TMS interventions to promote poststroke CST function.…”
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β2 integrin regulates neutrophil trans endothelial migration following traumatic brain injury by Lei Li, Ruilong Peng, Cong Wang, Xin Chen, Dilmurat Gheyret, Siyu Guan, Bo Chen, Yafan Liu, Xilei Liu, Yiyao Cao, Cha Han, Jianhua Xiong, Fanjian Li, Taoyuan Lu, Haoran Jia, Kaiji Li, Jinchao Wang, Xu Zhang, Jianye Xu, Yajuan Wang, Xin Xu, Tuo Li, Jianning Zhang, Shu Zhang

“…Abstract Neutrophils are the first responders among peripheral immune cells to infiltrate the central nervous system following a traumatic brain injury (TBI), triggering neuroinflammation that can exacerbate secondary tissue damage. …”
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Association of Psychological Resilience With Decelerated Brain Aging in Cognitively Healthy World Trade Center Responders by Saren H. Seeley, Rachel Fremont, Zoe Schreiber, Laurel S. Morris, Leah Cahn, James W. Murrough, Daniela Schiller, Dennis S. Charney, Robert H. Pietrzak, M. Mercedes Perez-Rodriguez, Adriana Feder

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Antiretroviral drug therapy does not reduce neuroinflammation in an HIV-1 infection brain organoid model by Samuel Martinez-Meza, Thomas A. Premeaux, Stefano M. Cirigliano, Courtney M. Friday, Stephanie Michael, Sonia Mediouni, Susana T. Valente, Lishomwa C. Ndhlovu, Howard A. Fine, Robert L. Furler O’Brien, Douglas F. Nixon

“…Abstract Background HIV-1-associated neurocognitive impairment (HIV-1-NCI) is marked by ongoing and chronic neuroinflammation with loss and decline in neuronal function even when antiretroviral drug therapy (ART) successfully suppresses viral replication. …”
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GAN-enhanced deep learning for improved Alzheimer's disease classification and longitudinal brain change analysis by Purushottam Pandey, Surbhi Bhatia Khan, Surbhi Bhatia Khan, Surbhi Bhatia Khan, Jyoti Pruthi, Eid Albalawi, Ali Algarni, Ahlam Almusharraf

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Differential involvement of neurotransmitter pathways in AD, bvFTD and MCI: Whole-brain MRI analysis by Ricardo Félix Morais, José Maria Sousa, Cemal Koba, Leon Andres, Tiago Jesus, Inês Baldeiras, Tiago Gil Oliveira, Isabel Santana

“…We performed volumetric and whole-brain correlation analyses to evaluate relationships between brain regional volumes (BRVs) and neurotransmitter pathways. …”
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Deep learning-based electroencephalic decoding of the phase-lagged transcranial alternating current stimulation by Jeongwook Kwon, Byoung-Kyong Min, Byoung-Kyong Min

“…Thus, EEG signals can decode online stimulation types, and task-related EEG spectral characteristics may indicate neuromodulatory activity during brain stimulation. This study could advance communicative strategies in brain–machine interfacing (BMI)-neuromodulation within a closed-loop system.…”
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A four-channel microfluidic model of the blood–brain and blood–cerebrospinal fluid barriers: fluid dynamics analysis by Pavel A. Libet, Leonid Y. Polynkin, Mikis R. Saridis, Egor V. Yakovlev, Sofia A. Korsakova, Alla B. Salmina, Anton S. Averchuk, Natalia A. Rozanova, Stanislav O. Yurchenko

“…Abstract Brain-on-a-chip is an emerging field involving microfluidic devices capable of mimicking the structure and function of the human brain. …”
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Brain computer interfaces for cognitive enhancement in older people - challenges and applications: a systematic review by Ping-Chen Tsai, Asangaedem Akpan, Kea-Tiong Tang, Heba Lakany

“…Future BCI research could focus on trial design and BCI performance gaps between the old and the young to develop a robust BCI system that compensates for age-related declines in cognitive and motor functions.…”
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Brain network and energy imbalance in Parkinson’s disease: linking ATP reduction and α-synuclein pathology by Hirohisa Watanabe, Sayuri Shima, Kazuya Kawabata, Yasuaki Mizutani, Akihiro Ueda, Akihiro Ueda, Mizuki Ito, Mizuki Ito

“…Cortical hubs, which are highly connected regions essential for coordinating multiple brain functions, require significant energy due to their dense synaptic activity and long-range connections. …”
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A Novel Frontier in Gut–Brain Axis Research: The Transplantation of Fecal Microbiota in Neurodegenerative Disorders by Majid Eslami, Zarifeh Adampour, Bahram Fadaee Dowlat, Shayan Yaghmayee, Faezeh Motallebi Tabaei, Valentyn Oksenych, Ramtin Naderian

“…The gut–brain axis (GBA) represents a sophisticated bidirectional communication system connecting the central nervous system (CNS) and the gastrointestinal (GI) tract. …”
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Human cerebral organoids: Complex, versatile, and human-relevant models of neural development and brain diseases by Raquel Coronel, Rosa González-Sastre, Patricia Mateos-Martínez, Laura Maeso, Elena Llorente-Beneyto, Sabela Martín-Benito, Viviana S. Costa Gagosian, Leonardo Foti, Ma Carmen González-Caballero, Victoria López-Alonso, Isabel Liste

“…In this context, human cerebral organoids have emerged as valuable tools offering a more complex, versatile, and human-relevant system than traditional animal models, which are often unable to replicate the intricate architecture and functionality of the human brain. …”
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CORRECTION OF DISTURBED NEUROIMMUNE INTERACTIONS IN EXPERIMENTAL TRAUMATIC BRAIN INJURY BY MEANS OF RECOMBINANT INTERLEUKIN 2 by S. N. Shanin, E. E. Fomicheva, T. A. Filatenkova, N. B. Serebryanaya

“…TBI is associated by multidirectional abnormalities of immune system, which affect quantity and functions of T-, B-, and NK-lymphocytes leading to infectious complications or autosensibilization. …”
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Association of brain-derived neurotrophic factor and nerve growth factor gene polymorphisms with susceptibility to migraine by Coskun S, Varol S, Ozdemir HH, Agacayak E, Aydın B, Kapan O, camkurt MA, Tunc S, Cevik MU

“…Neurotrophic factors, such as brain-derived neurotrophic factor (BDNF) and nerve growth factor (NGF), play an important role in central nervous system functioning, development, and modulation of pain. …”
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