The gut–eye axis: from brain neurodegenerative diseases to age-related macular degeneration by Qianzi Jin, Suyu Wang, Yujia Yao, Qin Jiang, Keran Li

“…In recent decades, significant evidence has indicated that the intestinal flora also influences systems outside of the digestive tract, including the brain. …”
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A Unique Case of Poorly Differentiated Neuroendocrine Carcinoma With Brain and Bilateral Adrenal Metastases by Carla J. El Hajj Mouawad, Francois Georges Kamar

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Stimulation mapping and whole-brain modeling reveal gradients of excitability and recurrence in cortical networks by Davide Momi, Zheng Wang, Sara Parmigiani, Ezequiel Mikulan, Sorenza P. Bastiaens, Mohammad P. Oveisi, Kevin Kadak, Gianluca Gaglioti, Allison C. Waters, Sean Hill, Andrea Pigorini, Corey J. Keller, John D. Griffiths

“…Abstract The human brain exhibits a modular and hierarchical structure, spanning low-order sensorimotor to high-order cognitive/affective systems. …”
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Brain lateralization for perceiving direction of motion is reversed in Williams syndrome and related to BUD23 by Debra L. Mills, Li Dai, Julie R. Korenberg

“…Abstract Lateralized nervous system function is phylogenetically old but fundamentally important for human brain function. …”
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Unraveling the interplay between sleep, redox metabolism, and aging: implications for brain health and longevity by Fayaz A. Mir, Fayaz A. Mir, Arianna R. S. Lark, Arianna R. S. Lark, Christa J. Nehs, Christa J. Nehs

“…Neurons, with their high energy demands, are particularly vulnerable to oxidative damage, making redox regulation crucial in maintaining brain integrity. This review explores the bidirectional relationship between sleep and redox metabolism through five key areas: (1) sleep’s role in free radical regulation, (2) ROS as mediators of age-related sleep disturbances, (3) feedback loops between impaired sleep and brain metabolism, (4) sleep, redox, and aging in peripheral systems, and (5) therapeutic strategies to restore redox balance and improve aging outcomes. …”
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The Safety of Using Body-Transmit MRI in Patients with Implanted Deep Brain Stimulation Devices. by Joshua Kahan, Anastasia Papadaki, Mark White, Laura Mancini, Tarek Yousry, Ludvic Zrinzo, Patricia Limousin, Marwan Hariz, Tom Foltynie, John Thornton

“…<h4>Background</h4>Deep brain stimulation (DBS) is an established treatment for patients with movement disorders. …”
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The effects of rifaximin and lactulose on the gut-liver-brain axis in rats with minimal hepatic encephalopathy. by Xueyan Lin, Zhengchao Zhang, Yi Lin, Shiyun Lu, Rongrong Chen

“…The Morris water maze (MWM) test was used to assess cognitive function in MHE rats following treatment with rifaximin and lactulose. …”
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Oxidative stress in the brain is regulated by social status in a highly social cichlid fish by Peter D. Dijkstra, Peter D. Dijkstra, Peter D. Dijkstra, Robert J. Fialkowski, Brady Bush, Ryan Y. Wong, Travis I. Moore, Ashley R. Harvey

“…Social stress can increase reactive oxygen species and derail antioxidant function in the brain, which may contribute to the onset and progression of mental health disorders. …”
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Promotion of recovery from Traumatic Brain Injury (TBI) by Granulocyte Colony-Stimulating Factor (G-CSF) treatment requires cannabinoid receptor type 2 activity by Shijie Song, Bangmei Wang, Xiaoyuan Kong, Niketa Patel, Juan Sanchez-Ramos, Mark S. Kindy

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Divergent brain solute clearance in rat models of cerebral amyloid angiopathy and Alzheimer’s disease by Sunil Koundal, Xinan Chen, Zachary Gursky, Hedok Lee, Kaiming Xu, Feng Liang, Zhongcong Xie, Feng Xu, Hung-Mo Lin, William E. Van Nostrand, Xianfeng Gu, Rena Elkin, Allen Tannenbaum, Helene Benveniste

“…The rTg-DI rats with severe CAA disease exhibited abnormal influx/clearance kinetics, while TgSD-AD rats with a moderate Aβ plaque load exhibited normal transport suggesting that different Aβ lesions and their overall burden differentially impact glymphatic system function.…”
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The brain-gut microbiota network (BGMN) is correlated with symptom severity and neurocognition in patients with schizophrenia by Runlin Peng, Wei Wang, Liqin Liang, Rui Han, Yi Li, Haiyuan Wang, Yuran Wang, Wenhao Li, Shixuan Feng, Jing Zhou, Yuanyuan Huang, Fengchun Wu, Kai Wu

“…First, the brain features of brain images and functional brain networks were computed from rs-fMRI data; the gut features of gut microbiota abundance and the gut microbiota network were computed from gut microbiota data. …”
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Microbial diversity and fitness in the gut–brain axis: influences on developmental risk for Alzheimer’s disease by Angelo M. Jamerlan, Seong Soo A. An, John P. Hulme

“…The gut–brain axis (GBA) denotes the dynamic and bidirectional communication system that connects the gastrointestinal tract and the central nervous system (CNS). …”
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NANOVESICLES IN THE GUT–BRAIN AXIS: INSIGHTS FROM PROBIOTIC SUPPLEMENTATION IN IRRITABLE BOWEL SYNDROME

“…Our findings suggest that probiotic-induced nanovesicles may influence CNS function through the gut–brain axis and help maintain gut homeostasis under stress. …”
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Vasohibins in Health and Disease: From Angiogenesis to Tumorigenesis, Multiorgan Dysfunction, and Brain–Heart Remodeling by Ghulam Abbas, Annet Kirabo, Usama Ahmed, Jie Liu, Jidong Chen

“…These findings suggest the pleiotropic effects of VASHs in multiple organs and systems beyond angiogenesis. This review explores the molecular properties of VASHs and their emerging functions in tubulin carboxyl activity and microtubule detyrosination—key to brain and cardiac remodeling. …”
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The interplay between physical exercise and autophagy signaling in brain health, neurodegenerative diseases and aging by Bo Gao, Li Wang, Jian Gong, Zehua Zhu, Qi Liu, Han Yuan, Haitao Wang

“…Brain health is increasingly recognized as a critical component of overall wellbeing, particularly concerning neurodegenerative diseases, which are characterized by the progressive degeneration of the nervous system. …”
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A human iPSC-Derived myelination model for investigating fetal brain injuries by Tsuyoshi Hiraiwa, Shoko Yoshii, Jiro Kawada, Tohru Sugawara, Tomoyuki Kawasaki, Shinsuke Shibata, Tomoko Shindo, Keiya Fujimori, Akihiro Umezawa, Hidenori Akutsu

“…The model successfully achieved axonal fascicle formation and compact myelin deposition, as validated by immunostaining and transmission electron microscopy. Functional calcium imaging confirmed neuronal activity within the system, underscoring its physiological relevance. …”
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Hijacking homeostasis: the brain-body neural circuitry in tumor pathogenesis and emerging therapeutic frontiers by Yong-Fei Wang, Zi-Kai Dong, Wei-Lin Jin

“…The theory of homeostasis is an important basis for explaining biological functions from the perspective of the organism. Organic homeostasis relies on brain-body crosstalk through interception, immunoception, nociception and other supervisory processes, guaranteeing normal physiological function. …”
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Redox metabolic disruptions in the honey bee brain following acute exposure to the pyrethroid deltamethrin by Máté Mackei, Fanni Huber, Barnabás Oláh, Zsuzsanna Neogrády, Gábor Mátis

“…The activities of the monitored enzymes, such as glucose-6-phosphate dehydrogenase (G6PDH), superoxide dismutase (SOD), and xanthine oxidase (XO), were significantly decreased, highlighting the altered function of the enzymatic antioxidant defense system. …”
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Blood-brain barrier repair: potential and challenges of stem cells and exosomes in stroke treatment by Xiaochen Fu, Xiaochen Fu, Jia Li, Jia Li, Shoujun Yang, Jiapeng Jing, Jiapeng Jing, Qinzhi Zheng, Qinzhi Zheng, Ting Zhang, Ting Zhang, Zhuo Xu

“…Stroke is characterized with high morbidity, mortality and disability all over the world, and one of its core pathologies is blood-brain barrier (BBB) dysfunction. BBB plays a crucial physiological role in protecting brain tissues and maintaining homeostasis in central nervous system (CNS). …”
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Brain alterations and neurologic disorder progression induced by lymphatic dysfunction in the head and neck region by Hwayeong Cheon, Dong-Cheol Woo, Seungwoo Cha, Yeon Ji Chae, Inhee Maeng, Seung Jae Oh, Jae Yong Jeon

“…Emerging evidence suggests that waste clearance and fluidic balance in the brain are connected to the peripheral lymphatic system in the head and neck region, implying that lymphatic injury in this area could contribute to brain damage. …”
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