Suggested Topics within your search.
Suggested Topics within your search.
-
1021
Review of Brain Computer Interface Technology in the Treatment of Motor Dysfunction after Stroke
Published 2020-04-01“…It is mainly through the methods of recovery and replacement to promote the brain plasticity of stroke patients, so as to help the motor function of stroke patients in rehabilitation. …”
Get full text
Article -
1022
Simultaneous Multi-Treatment Strategy for Brain Tumor Reduction via Nonlinear Control
Published 2025-02-01“…<b>Methods</b>: This study updates the recently proposed brain-tumor system dynamics by incorporating radiotherapy along with chemotherapy to simultaneously initiate both therapies for a more comprehensive and effective response against tumor proliferation. …”
Get full text
Article -
1023
Traversing the epigenetic landscape: DNA methylation from retina to brain in development and disease
Published 2024-11-01“…We further extend our exploration from the retina to the brain, examining the role of DNA methylation in brain development and its associated diseases, such as Alzheimer’s disease (AD) and Huntington’s disease (HD) to better understand the mechanistic links between retinal and brain diseases, and explore the possibility of communication between the visual system and the central nervous system (CNS) from an epigenetic perspective. …”
Get full text
Article -
1024
Regional-specific activation of phagocytosis in the rat brain in the conditions of sepsis-associated encephalopathy
Published 2021-02-01“…The main cell population of the brain responsible for the immune surveillance is microglia, and its phagocytic activity is a fundamental function providing both homeostatic and damaging properties. …”
Get full text
Article -
1025
Cutibacterium Acnes induces Alzheimer’s disease-like pathology in brains of wistar rats through structural changes associated with microtubules
Published 2024-11-01“…Abstract Background Cutibacterium acnes ( C. acnes), a Gram-positive anaerobe and a dominant bacterium species in the sebaceous follicles of the face was detected in the brain of Alzheimer’s disease (AD) patients. It has been found that C. acnes activates non-specifically the innate immune system by producing proinflammatory cytokines and can participate in brain inflammation. …”
Get full text
Article -
1026
Unraveling cysteinyl leukotrienes and their receptors in inflammation through the brain-gut-lung axis
Published 2025-12-01“…It is indicated that CysLTs activate eosinophils, mast cells, and airway tuft cells, driving type 2 immune responses and mucus secretion in the lungs, thereby exacerbating respiratory diseases such as asthma. In the nervous system, CysLTs aggravate neurodegenerative disorders like cerebral ischemia and Alzheimer’s disease by disrupting the blood-brain barrier, promoting glial activation, and inducing neuronal damage. …”
Get full text
Article -
1027
In Vitro Evaluation of the Efficient Passage of PLGA-Formulated Trastuzumab for Nose-to-Brain Delivery
Published 2025-05-01“…In contrast, no passage was observed across the BBB, supporting the notion of the superiority of the nose–brain route over systemic injection for in vivo delivery of TZB to the central nervous system.…”
Get full text
Article -
1028
The Role of Cytokine Gene Polymorphisms in Rehabilitation Outcome After Traumatic Brain Injury
Published 2025-07-01“…Traumatic brain injury (TBI) affects millions of people worldwide and often results in long-term disabilities. …”
Get full text
Article -
1029
THE PATHOGENIC SIGNIFICANCE OF IMMUNOLOGICAL DISORDERS IN COMBINED TRAUMATIC BRAIN INJURY AND TOURNIQUET TOXEMIA
Published 2013-12-01“…Disorders of immune system functional activity in the combined brain injury pathogenesis against traumatic intoxication always lead to development of pyo-inflammatory complications. …”
Get full text
Article -
1030
Establishment and application of a brain cell line derived from Plectropomus leopardus
Published 2024-12-01“…In summary, PLB cell lines represent a promising tool for conducting in vitro analyses of foreign gene functionality, bacterial susceptibility, and heavy metal toxicity. …”
Get full text
Article -
1031
Astrocyte-mediated inflammatory responses in traumatic brain injury: mechanisms and potential interventions
Published 2025-05-01Get full text
Article -
1032
Characteristics of lead in lung and brain reveals respiration as a direct exposure way
Published 2025-05-01“…Although Pb exposure is reported to be associated with brain functional impairment, there remain gaps to directly clarify their links and how the environmental lead entry into brain is rarely known. …”
Get full text
Article -
1033
The gut microbiome, immune modulation, and cognitive decline: insights on the gut-brain axis
Published 2025-01-01“…The gut microbiome has emerged as a pivotal area of research due to its significant influence on the immune system and cognitive functions. Cognitive disorders, including dementia and Parkinson’s disease, represent substantial global health challenges. …”
Get full text
Article -
1034
Hemostasis Disturbances in Patients in the Acute Period of Isolated Traumatic Brain Injury (Review)
Published 2018-10-01“…Acute isolated traumatic brain injury (TBI) is frequently associated with occurrence of hemostasis disorders, which may be accompanied with hemorrhagic and ischemic events in the brain matter, hence, normal functioning of the blood coagulation system is critical. …”
Get full text
Article -
1035
Distribution of N-Acetylgalactosamine-Positive Perineuronal Nets in the Macaque Brain: Anatomy and Implications
Published 2016-01-01“…The incidence of perineuronal nets around parvalbumin-positive neurons (putative fast-spiking interneurons) varies considerably between different areas in the brain. Our survey indicates that the presence of PNNs may not have a simple relationship with neural plasticity and may serve multiple functions in the central nervous system.…”
Get full text
Article -
1036
Hypothalamus-pituitary-adrenal and gut-brain axes in biological interaction pathway of the depression
Published 2025-02-01“…The HPA axis regulates the body's stress response, and chronic stress can lead to overactivation of the HPA axis, resulting in elevated cortisol levels that contribute to neuronal damage, particularly in regions such as the hippocampus and prefrontal cortex, both of which are involved in mood regulation and mental disorders. In parallel, the gut-brain axis, a bidirectional communication network between the gut microbiota and the central nervous system, influences emotional and cognitive functions. …”
Get full text
Article -
1037
A Brain Centred View of Psychiatric Comorbidity in Tinnitus: From Otology to Hodology
Published 2014-01-01“…Discussion. Several overlapping brain network alterations do exist between tinnitus and psychiatric disorders. …”
Get full text
Article -
1038
Gut Microbiota and Gut-Brain Axis in Health and Disease A Narrative Review
Published 2025-05-01“…Major metabolites such as SCFAs help with the regulation of immune functions, act as protectors of the blood-brain barrier, and are known to support neuroprotection, while deleterious substances such as TMAO find association with cardiovascular diseases. …”
Get full text
Article -
1039
-
1040
Microglia in the aged brain develop a hypoactive molecular phenotype after surgery
Published 2024-12-01“…Abstract Background Microglia, the resident immune cells of the brain, play a crucial role in maintaining homeostasis in the central nervous system (CNS). …”
Get full text
Article