Suggested Topics within your search.
Suggested Topics within your search.
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921
Building a social brain: Cells, circuits and behavior across the lifespan
Published 2025-05-01“…These studies have employed multiple levels of analysis and functional brain dissection to identify novel targets of early social stress and measure how the infant brain responds to social information in typical and perturbed development.…”
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922
Neuroplasticity and tinnitus: the role of Brain-Derived Neurotrophic Factor in pathogenesis and treatment
Published 2025-07-01“…Animal studies have demonstrated that tinnitus is associated with synaptic plasticity dysfunction in multiple brain regions, including the auditory and limbic systems. …”
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923
Alterations of Regional Spontaneous Brain Activity and Gray Matter Volume in the Blind
Published 2015-01-01“…Visual deprivation can induce alterations of regional spontaneous brain activity (RSBA). However, the effects of onset age of blindness on the RSBA and the association between the alterations of RSBA and brain structure are still unclear in the blind. …”
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924
Centella asiatica Nanoparticles as Potential Acetylcholinesterase Inhibitor for Cognitive Decline Therapy using Ellman's Method: An in Vitro Study
Published 2024-12-01“…This research contributes novel data to current studies by combining the potential of Centella asiatica extract with PEG-400 to develop a therapeutic agent aimed at improving cognitive function through an effective drug delivery system capable of penetrating the blood-brain barrier. 2. …”
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925
Genetic insights and molecular pathways in Alzheimer's disease: Unveiling the complexity of neurodegeneration
Published 2025-03-01“…Upregulated genes include DDX3Y, H6PD and KIF1B, while down-regulated genes include CREM, CD44, and HES4. Functional enrichment analysis using Enrichr revealed significantly upregulated pathways, including the PI3K-Akt signalling and Wnt signalling pathways. …”
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926
Repurposing major metabolites of lamiaceae family as potential inhibitors of α-synuclein aggregation to alleviate neurodegenerative diseases: an in silico approach
Published 2025-04-01“…Neurodegenerative disorders (NDs) are typically characterized by progressive loss of neuronal function and the deposition of misfolded proteins in the brain and peripheral organs. …”
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927
The Neurodevelopmental Perspective of Surgical Necrotizing Enterocolitis: The Role of the Gut-Brain Axis
Published 2018-01-01“…The type of initial surgical approach correlates with the length of functional gut and microbiome equilibrium influencing brain development and function through the gut-brain axis. …”
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928
The dynamic brain: from spiking neurons to neural masses and cortical fields.
Published 2008-08-01“…The cortex is a complex system, characterized by its dynamics and architecture, which underlie many functions such as action, perception, learning, language, and cognition. …”
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929
Novel AP39-Loaded Liposomes Sustain the Release of Hydrogen Sulphide, Enhance Blood-Brain Barrier Permeation, and Abrogate Oxidative Stress-Induced Mitochondrial Dysfunction in Bra...
Published 2025-03-01“…However, its clinical application is limited due to poor stability and rapid release, necessitating a drug delivery system to enhance therapeutic efficacy.Purpose: This study aimed to develop a novel AP39-loaded liposomal formulation to provide controlled H2S release, facilitate AP39 permeation across the blood-brain barrier (BBB), and assess functional effects in mitigating oxidative stress and preserving mitochondrial function.Methods: AP39-loaded unilamellar liposomes were prepared via ethanol injection and characterised for size, polydispersity, and zeta potential. …”
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931
Regional and aging-specific cellular architecture of non-human primate brains
Published 2025-04-01“…Conclusions Taken together, our study presents a valuable resource for investigating the cellular and molecular architecture of the primate nervous system, thereby expanding our understanding of the mechanisms underlying brain function, aging, and disease.…”
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932
Controlling Assistive Machines in Paralysis Using Brain Waves and Other Biosignals
Published 2013-01-01“…However, these communication channels depend on a functional motor system. As many people suffer from severe damage of the motor system resulting in paralysis and inability to communicate, the development of brain-machine interfaces (BMI) that translate electric or metabolic brain activity into control signals of external devices promises to overcome this dependence. …”
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933
Glutathione in Cerebral Microvascular Endothelial Biology and Pathobiology: Implications for Brain Homeostasis
Published 2012-01-01“…Given the function of the BBB as a physical and metabolic barrier that buffers the systemic environment, oxidative damage to the endothelial monolayer will have significant deleterious impact on the metabolic, immunological, and neurological functions of the brain. …”
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934
Psychoemotional and cognitive characteristics in patients at the early stages of Parkinson’s disease
Published 2020-04-01“…The cognitive functions were examined by the Montreal Cognitive Assessment (MoCA) scale and cognitive evoked potentials (CEP) P300. …”
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935
The Effects of Probiotic Supplementation on Level of Disability, Depressive Symptoms, and Cognitive Outcomes in Relapsing-Remitting Multiple Sclerosis Patients: A Randomized Double...
Published 2025-07-01“…Background: Multiple sclerosis (MS) is a chronic autoimmune disease characterized by inflammation and demyelination of the central nervous system. Probiotics, through the gut-brain axis, are suggested to enhance clinical outcomes in patients with MS. …”
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936
A Distribution Adaptive Feedback Training Method to Improve Human Motor Imagery Ability
Published 2025-01-01“…A brain-computer interface (BCI) based on motor imagery (MI) can translate users’ subjective movement-related mental state without external stimulus, which has been successfully used for replacing and repairing motor function. …”
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937
Diagnostic ultrasound enhances, then reduces, exogenously induced brain activity of mice
Published 2025-02-01“…Given the near ubiquity of diagnostic ultrasound systems, further progress along this line of research could one day lead to the widespread use of diagnostic ultrasound to intentionally modulate human brain function during exogenous stimulation.…”
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938
Mitochondria targeted nanoparticles for the treatment of mitochondrial dysfunction-associated brain disorders
Published 2025-03-01“…This article provides a detailed overview of studies that have investigated the treatment of mitochondrial dysfunction in brain disorders using either targeted or non-targeted NPs as drug delivery systems. …”
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940
Boosting proactive motor control via statistical learning with brain stimulation
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