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881
Myelin dysfunction in aging and brain disorders: mechanisms and therapeutic opportunities
Published 2025-06-01“…Abstract Myelin is a multilamellar membrane that surrounds axons in the vertebrate nervous system. Properly functioning myelin is essential for the rapid conduction of nerve impulses, and it metabolically supports axonal integrity. …”
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882
Antioxidant Bioactive Agents for Neuroprotection Against Perinatal Brain Injury
Published 2025-05-01“…While moderate oxidative stress is essential for activating key metabolic pathways and maintaining normal cellular signaling, excessive production of reactive oxygen species (ROSs) can overwhelm the immature antioxidant systems of newborns, potentially leading to cellular damage and impaired physiological function. …”
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883
The nasal lymphatic route of CSF outflow: implications for neurodegenerative disease diagnosis and monitoring
Published 2024-12-01“…Cerebrospinal fluid (CSF) plays a crucial role in the brain's lymphatics as it traverses the central nervous system (CNS). …”
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884
CLINICAL SIGNIFICANCE OF N-TERMINAL FRAGMENT OF NATRIURETIC PEPTIDE IN PATIENTS WITH SYSTEMIC LUPUS ERYTHEMATOSUS WHO DO NOT RECEIVE PATHOGENETIC THERAPY
Published 2017-09-01“…Objective: to determine the level of the N-terminal fragment of brain natriuretic peptide progenitor (NT-proBNP) in patients with systemic lupus erythematous (SLE) prior to immunosuppressive therapy and its possible association with inflammatory markers, traditional risk factors (TRFs) for cardiovascular diseases (CVD), and transthoracic echocardiographic (EchoCG) parameters.Subjects and methods. …”
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885
A.R. Luria's contribution to studies of the brain organization of language
Published 2020-02-01“…It considers the concepts of functional systems, systemic and dynamic organization of speech, proposed by A.R. …”
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886
Towards developing brain-computer interfaces for people with Multiple Sclerosis.
Published 2025-01-01“…<h4>Background</h4>Multiple Sclerosis (MS) can be a severely disabling condition that leads to various neurological symptoms. A Brain-Computer Interface (BCI) may substitute some lost function; however, there is a lack of BCI research in people with MS. …”
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887
Vascular endotelial dysfunction is a pathogenetic factor in the development of neurodegenerative diseases and cognitive impairment
Published 2020-10-01“…Of the genetic diseases, the most studied are monogenic diseases associated with impaired blood-brain barrier integrity: this is a deficiency of protein molecules that ensure glucose transport, structural and functional integrity of tight junctions and the basement membrane of endothelial cells themselves, as well as mutations in pericytes and smooth muscle cells. …”
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888
What is the pathophysiology of inflammation-induced cortical injury in the perinatal brain?
Published 2026-02-01“…However, our understanding of the pathophysiological substrate underpinning these changes in brain structure and function is limited. The objective of this review is to summarize the growing evidence from animal trials and human cohort studies that suggest exposure to infection/inflammation during the perinatal period promotes regional impairments in neuronal maturation and function, including loss of high-frequency electroencephalographic activity, and reduced growth and arborization of cortical dendrites and dendritic spines resulting in reduced cortical volume. …”
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889
Brain state monitoring and neuromodulation in sleep disorders: current perspectives
Published 2025-06-01“…Recent findings Current research has revealed that BDMS, such as electroencephalography (EEG), functional magnetic resonance imaging (fMRI), and functional near-infrared spectroscopy (fNIRS), have significant potential for identifying brain activity patterns in sleep disorders, especially insomnia and sleep apnea. …”
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890
Brief exposure to obesogenic diet disrupts brain dopamine networks.
Published 2018-01-01“…Because AMPH induces DA efflux and brain activation, in large part via DAT, these findings suggest that blunted central nervous system insulin receptor signaling through a HF diet can impair DA homeostasis, thereby disrupting cognitive and reward circuitry involved in the regulation of hedonic feeding.…”
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891
Focus on Brain Angiotensin III and Aminopeptidase A in the Control of Hypertension
Published 2012-01-01“…The discovery of a brain RAS composed of the necessary functional components (angiotensinogen, peptidases, angiotensins, and specific receptor proteins) independent of the peripheral system significantly expanded the possible physiological and pharmacological functions of this system. …”
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892
Brain Tumour Segmentation Using Choquet Integrals and Coalition Game
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893
UCLN: Toward the Causal Understanding of Brain Disorders With Temporal Lag Dynamics
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894
From Brain to Muscle: The Role of Muscle Tissue in Neurodegenerative Disorders
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895
A Systematic Review of Bimanual Motor Coordination in Brain-Computer Interface
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896
Recent progress on nanotechnologies for enhancing blood‐brain barrier permeability
Published 2025-06-01“…Abstract The blood‐brain barrier (BBB) is a substantial impediment to effectively delivering central nervous system (CNS) therapies. …”
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897
Bone-brain interaction: mechanisms and potential intervention strategies of biomaterials
Published 2025-03-01“…Abstract Following the discovery of bone as an endocrine organ with systemic influence, bone-brain interaction has emerged as a research hotspot, unveiling complex bidirectional communication between bone and brain. …”
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898
Localization and connections of the tail of caudate and caudal putamen in mouse brain
Published 2025-08-01“…These findings would offer new insights into the functional correlation and disease-related neural circuits related to the caudal striatum.…”
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899
An untargeted metabolomics analysis in feces and brain of Orthoflaviviruses-infected mice
Published 2025-07-01“…The disruption of purine metabolism also implies the viral genome replication process occurring in the brain. Moreover, the disturbance of lipid metabolism is highly correlated with the biological function of the Orthoflavivirus envelope, where Sphingosine 1-phosphate (S1P) may be the key for Orthoflaviviruses to enter the human central nervous system via the GBA. …”
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900
Exploring organoid and assembloid technologies: a focus on retina and brain
Published 2025-01-01“… Abstract Background The recent emergence of three-dimensional organoids and their utilization as in vitro disease models confirmed the complexities behind organ-specific functions and unravelled the importance of establishing suitable human models for various applications. …”
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