Showing 881 - 900 results of 3,447 for search '(functional OR function) brain systems', query time: 0.18s Refine Results
  1. 881

    Myelin dysfunction in aging and brain disorders: mechanisms and therapeutic opportunities by Zhihai Huang, Yulan Zhang, Peibin Zou, Xuemei Zong, Quanguang Zhang

    Published 2025-06-01
    “…Abstract Myelin is a multilamellar membrane that surrounds axons in the vertebrate nervous system. Properly functioning myelin is essential for the rapid conduction of nerve impulses, and it metabolically supports axonal integrity. …”
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  2. 882

    Antioxidant Bioactive Agents for Neuroprotection Against Perinatal Brain Injury by Virginia Beretta, Elena Scarpa, Silvia Carloni, Chiara Petrolini, Valentina Dell’Orto, Sebastiano Ravenda, Serafina Perrone

    Published 2025-05-01
    “…While moderate oxidative stress is essential for activating key metabolic pathways and maintaining normal cellular signaling, excessive production of reactive oxygen species (ROSs) can overwhelm the immature antioxidant systems of newborns, potentially leading to cellular damage and impaired physiological function. …”
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  3. 883

    The nasal lymphatic route of CSF outflow: implications for neurodegenerative disease diagnosis and monitoring by Jiwon Chae, Mina Choi, Juyoung Choi, Seung-Jun Yoo

    Published 2024-12-01
    “…Cerebrospinal fluid (CSF) plays a crucial role in the brain's lymphatics as it traverses the central nervous system (CNS). …”
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  4. 884

    CLINICAL SIGNIFICANCE OF N-TERMINAL FRAGMENT OF NATRIURETIC PEPTIDE IN PATIENTS WITH SYSTEMIC LUPUS ERYTHEMATOSUS WHO DO NOT RECEIVE PATHOGENETIC THERAPY by T. A. Panafidina, M. A. Sokhova, T. V. Popkova, D. S. Novikova, E. N. Aleksandrova, Yu. O. Korsakova, A. V. Volkov

    Published 2017-09-01
    “…Objective: to determine the level of the N-terminal fragment of brain natriuretic peptide progenitor (NT-proBNP) in patients with systemic lupus erythematous (SLE) prior to immunosuppressive therapy and its possible association with inflammatory markers, traditional risk factors (TRFs) for cardiovascular diseases (CVD), and transthoracic echocardiographic (EchoCG) parameters.Subjects and methods. …”
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  5. 885

    A.R. Luria's contribution to studies of the brain organization of language by A. Ardila, T. V. Akhutina, Yu. V. Mikadze

    Published 2020-02-01
    “…It considers the concepts of functional systems, systemic and dynamic organization of speech, proposed by A.R. …”
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  6. 886

    Towards developing brain-computer interfaces for people with Multiple Sclerosis. by John S Russo, Tim Mahoney, Kirill Kokorin, Ashley Reynolds, Chin-Hsuan Sophie Lin, Sam E John, David B Grayden

    Published 2025-01-01
    “…<h4>Background</h4>Multiple Sclerosis (MS) can be a severely disabling condition that leads to various neurological symptoms. A Brain-Computer Interface (BCI) may substitute some lost function; however, there is a lack of BCI research in people with MS. …”
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  7. 887

    Vascular endotelial dysfunction is a pathogenetic factor in the development of neurodegenerative diseases and cognitive impairment by N. V. Goncharov, P. I. Popova, A. S. Golovkin, N. M. Zalutskaya, E. I. Palchikova, K. V. Zanin, Р. V. Avdonin

    Published 2020-10-01
    “…Of the genetic diseases, the most studied are monogenic diseases associated with impaired blood-brain barrier integrity: this is a deficiency of protein molecules that ensure glucose transport, structural and functional integrity of tight junctions and the basement membrane of endothelial cells themselves, as well as mutations in pericytes and smooth muscle cells. …”
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  8. 888

    What is the pathophysiology of inflammation-induced cortical injury in the perinatal brain? by Sharmony B. Kelly, Alistair J. Gunn, Rodney W. Hunt, Robert Galinsky

    Published 2026-02-01
    “…However, our understanding of the pathophysiological substrate underpinning these changes in brain structure and function is limited. The objective of this review is to summarize the growing evidence from animal trials and human cohort studies that suggest exposure to infection/inflammation during the perinatal period promotes regional impairments in neuronal maturation and function, including loss of high-frequency electroencephalographic activity, and reduced growth and arborization of cortical dendrites and dendritic spines resulting in reduced cortical volume. …”
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  9. 889

    Brain state monitoring and neuromodulation in sleep disorders: current perspectives by Xiaolin Wang, Jing Li, Xiaowei Li, Dan Zhang, Yan Peng

    Published 2025-06-01
    “…Recent findings Current research has revealed that BDMS, such as electroencephalography (EEG), functional magnetic resonance imaging (fMRI), and functional near-infrared spectroscopy (fNIRS), have significant potential for identifying brain activity patterns in sleep disorders, especially insomnia and sleep apnea. …”
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  10. 890

    Brief exposure to obesogenic diet disrupts brain dopamine networks. by Robert L Barry, Nellie E Byun, Jason M Williams, Michael A Siuta, Mohammed N Tantawy, Nicole K Speed, Christine Saunders, Aurelio Galli, Kevin D Niswender, Malcolm J Avison

    Published 2018-01-01
    “…Because AMPH induces DA efflux and brain activation, in large part via DAT, these findings suggest that blunted central nervous system insulin receptor signaling through a HF diet can impair DA homeostasis, thereby disrupting cognitive and reward circuitry involved in the regulation of hedonic feeding.…”
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  11. 891

    Focus on Brain Angiotensin III and Aminopeptidase A in the Control of Hypertension by John W. Wright, Shigehiko Mizutani, Joseph W. Harding

    Published 2012-01-01
    “…The discovery of a brain RAS composed of the necessary functional components (angiotensinogen, peptidases, angiotensins, and specific receptor proteins) independent of the peripheral system significantly expanded the possible physiological and pharmacological functions of this system. …”
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  12. 892
  13. 893
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  16. 896

    Recent progress on nanotechnologies for enhancing blood‐brain barrier permeability by Qibin Liu, Zhuoqian Chen, Anthony Guiseppi‐Elie, Fanling Meng, Liang Luo

    Published 2025-06-01
    “…Abstract The blood‐brain barrier (BBB) is a substantial impediment to effectively delivering central nervous system (CNS) therapies. …”
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  17. 897

    Bone-brain interaction: mechanisms and potential intervention strategies of biomaterials by Jiaze Yu, Luli Ji, Yongxian Liu, Xiaogang Wang, Jing Wang, Changsheng Liu

    Published 2025-03-01
    “…Abstract Following the discovery of bone as an endocrine organ with systemic influence, bone-brain interaction has emerged as a research hotspot, unveiling complex bidirectional communication between bone and brain. …”
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  18. 898

    Localization and connections of the tail of caudate and caudal putamen in mouse brain by Run-Zhe Ma, Sheng-Qiang Chen, Ge Zhu, Hui-Ru Cai, Jin-Yuan Zhang, Yi-Min Peng, Dian Lian, Song-Lin Ding, Song-Lin Ding

    Published 2025-08-01
    “…These findings would offer new insights into the functional correlation and disease-related neural circuits related to the caudal striatum.…”
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  19. 899

    An untargeted metabolomics analysis in feces and brain of Orthoflaviviruses-infected mice by Zhiwei Su, Ningze Sun, Chenghong Yin, Xiaoyan Zheng

    Published 2025-07-01
    “…The disruption of purine metabolism also implies the viral genome replication process occurring in the brain. Moreover, the disturbance of lipid metabolism is highly correlated with the biological function of the Orthoflavivirus envelope, where Sphingosine 1-phosphate (S1P) may be the key for Orthoflaviviruses to enter the human central nervous system via the GBA. …”
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  20. 900

    Exploring organoid and assembloid technologies: a focus on retina and brain by Sara Ouaidat, Alessandro Bellapianta, Franziska Ammer-Pickhardt, Tara Taghipour, Matthias Bolz, Ahmad Salti

    Published 2025-01-01
    “… Abstract Background The recent emergence of three-dimensional organoids and their utilization as in vitro disease models confirmed the complexities behind organ-specific functions and unravelled the importance of establishing suitable human models for various applications. …”
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