Anatomical heterogeneity in low-grade and high-grade gliomas: A multiscale perspective by Shengpeng Liang, Nuo Dong, Yumin Chen, Yang Yang, Haibing Xu

“…First, we generated glioma frequency maps based on tumor grade, neurotransmitters, and IDH-1 status and constructed a brain functional connectivity network to explore heterogeneity in glioma location. …”
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The hexapeptide functionalized gold nanoparticles protect against sepsis-associated encephalopathy by forming specific protein corona and regulating macrophage activation by Zichen Song, Hongguang Chen, Wenfei Xu, Xiaoye Zong, Xiaoyu Wang, Yuting Ji, Jiameng Gong, Mimi Pang, Shan-Yu Fung, Hong Yang, Yonghao Yu

“…Sepsis-induced systemic inflammatory responses can often lead to brain dysfunction with impaired cognitive function and mobility, known as sepsis-associated encephalopathy (SAE). …”
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Perturbations of microRNA function in mouse dicer mutants produce retinal defects and lead to aberrant axon pathfinding at the optic chiasm. by Rita Pinter, Robert Hindges

“…<h4>Conclusions</h4>Our work demonstrates an important role of Dicer controlling the extension of RGC axons to the brain proper. It indicates that miRNAs are essential regulatory elements for mechanisms that ensure correct axon guidance decisions at the midline and thus have a central function in the establishment of circuitry during the development of the nervous system.…”
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Development of blood-brain barrier-penetrating antibodies for neutralizing tick-borne encephalitis virus in the brain by Mizuki Fukuta, Sayo Fukano, Naoya Maekawa, Shintaro Kobayashi, Shunsuke Okamoto, Minato Hirano, Junko Nio-Kobayashi, Hiroaki Kariwa, Shigeru Kawakami, Satoru Konnai, Kentaro Yoshii

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Mapping variants in thyroid hormone transporter MCT8 to disease severity by genomic, phenotypic, functional, structural and deep learning integration by Stefan Groeneweg, Ferdy S. van Geest, Mariano Martín, Mafalda Dias, Jonathan Frazer, Carolina Medina-Gomez, Rosalie B. T. M. Sterenborg, Hao Wang, Anna Dolcetta-Capuzzo, Linda J. de Rooij, Alexander Teumer, Ayhan Abaci, Erica L. T. van den Akker, Gautam P. Ambegaonkar, Christine M. Armour, Iiuliu Bacos, Priyanka Bakhtiani, Diana Barca, Andrew J. Bauer, Sjoerd A. A. van den Berg, Amanda van den Berge, Enrico Bertini, Ingrid M. van Beynum, Nicola Brunetti-Pierri, Doris Brunner, Marco Cappa, Gerarda Cappuccio, Barbara Castellotti, Claudia Castiglioni, Krishna Chatterjee, Alexander Chesover, Peter Christian, Jet Coenen-van der Spek, Irenaeus F. M. de Coo, Regis Coutant, Dana Craiu, Patricia Crock, Christian DeGoede, Korcan Demir, Cheyenne Dewey, Alice Dica, Paul Dimitri, Marjolein H. G. Dremmen, Rachana Dubey, Anina Enderli, Jan Fairchild, Jonathan Gallichan, Luigi Garibaldi, Belinda George, Evelien F. Gevers, Erin Greenup, Annette Hackenberg, Zita Halász, Bianka Heinrich, Anna C. Hurst, Tony Huynh, Amber R. Isaza, Anna Klosowska, Marieke M. van der Knoop, Daniel Konrad, David A. Koolen, Heiko Krude, Abhishek Kulkarni, Alexander Laemmle, Stephen H. LaFranchi, Amy Lawson-Yuen, Jan Lebl, Selmar Leeuwenburgh, Michaela Linder-Lucht, Anna López Martí, Cláudia F. Lorea, Charles M. Lourenço, Roelineke J. Lunsing, Greta Lyons, Jana Krenek Malikova, Edna E. Mancilla, Kenneth L. McCormick, Anne McGowan, Veronica Mericq, Felipe Monti Lora, Carla Moran, Katalin E. Muller, Lindsey E. Nicol, Isabelle Oliver-Petit, Laura Paone, Praveen G. Paul, Michel Polak, Francesco Porta, Fabiano O. Poswar, Christina Reinauer, Klara Rozenkova, Rowen Seckold, Tuba Seven Menevse, Peter Simm, Anna Simon, Yogen Singh, Marco Spada, Milou A. M. Stals, Merel T. Stegenga, Athanasia Stoupa, Gopinath M. Subramanian, Lilla Szeifert, Davide Tonduti, Serap Turan, Joel Vanderniet, Adri van der Walt, Jean-Louis Wémeau, Anne-Marie van Wermeskerken, Jolanta Wierzba, Marie-Claire Y. de Wit, Nicole I. Wolf, Michael Wurm, Federica Zibordi, Amnon Zung, Nitash Zwaveling-Soonawala, Fernando Rivadeneira, Marcel E. Meima, Debora S. Marks, Juan P. Nicola, Chi-Hua Chen, Marco Medici, W. Edward Visser

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A systematic review of the literature in relation to the theoretical knowledge base for the-Clinical-functional research by evaluation including the modern apparatus modality of fu... by Irina Raluca Petcu, Gelu Onose

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Predictors of uveitic macular edema and functional prognostic outcomes: real-life data from the international AIDA Network uveitis registry by Jurgen Sota, Germán Mejía-Salgado, Silvana Guerriero, Gaafar Ragab, Gaafar Ragab, Stefania Costi, Maria Pia Paroli, Andrea Hinojosa-Azaola, Giuseppe Lopalco, Luciana Breda, Henrique Ayres Mayrink Giardini, Alex Fonollosa, Maria Sole Chimenti, Antonio Vitale, Carla Gaggiano, Blanca Aguilar-Barrera, Laura Daniela Rodríguez-Camelo, Guillermo Arturo Guaracha-Basañez, Mohamed Tharwat Hegazy, Mohamed Tharwat Hegazy, Rosanna Dammacco, Valeria Albano, Eduardo Martín-Nares, Santiago Espinosa-Lugo, Mahmoud Ghanema, Maria Morrone, Saverio La Bella, Rafael Alves Cordeiro, Francesco Carubbi, Alessandro Conforti, Piero Ruscitti, Ibrahim AlMaglouth, Rosaria Talarico, Stefano Gentileschi, Petros P. Sfikakis, Valeria Caggiano, Matteo Piga, Adele Civino, Francesca Ricci, Maissa Thabet, Marcello Govoni, Abdurrahman Tufan, Francesca Crisafulli, Jessica Sbalchiero, Sulaiman M. Al-Mayouf, Angela Mauro, Angela Mauro, Soad Hashad, Soad Hashad, Francesca Minoia, Alma Nunzia Olivieri, Samar Tharwat, Samar Tharwat, Maria Cristina Maggio, Abdelhfeez Moshrif, Gian Domenico Sebastiani, Daniela Opris-Belinski, Gülen Hatemi, Gülen Hatemi, Haner Direskeneli, Fatma Alibaz-Öner, Lampros Fotis, José Hernández-Rodríguez, Giovanni Conti, Piercarlo Sarzi Puttini, Ombretta Viapiana, Annarita Giardina, Patrizia Barone, Kalpana Babu, Rana Hussein Amin, Perla Ayumi Kawakami-Campos, Vishali Gupta, Annamaria Iagnocco, Ali Şahin, Antonella Insalaco, Andrés González-García, Ezgi Deniz Batu, Ester Carreño, Emanuela Del Giudice, Cecilia Beatrice Chighizola, Cecilia Beatrice Chighizola, Fabrizio Conti, Alberto Balistreri, Bruno Frediani, Luca Cantarini, Alejandra de-la-Torre, Claudia Fabiani

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Functional Involvement of Melatonin and Its Receptors in Reproductive Regulation of the Marine Teleost, Large Yellow Croaker (<i>Larimichthys crocea</i>) by Xudong Liang, Jixiu Wang, Baoyi Huang, Haojie Yuan, Yucheng Ren, Chenqian Wu, Tianming Wang, Jingwen Yang

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Glycoproteomics analysis of complement factor H and its complement-regulatory function during Streptococcus pneumoniae-associated hemolytic uremic syndrome by Laura M. Baas, Kioa L. Wijnsma, Fokje Zijlstra, Nicole C. A. J. van de Kar, Lieke ter Steeg, Antonia H. M. Bouts, Marloes A. H. M. Michels, Marloes A. H. M. Michels, Jeroen D. Langereis, Dirk Lefeber, Dirk Lefeber, Hans J. C. T. Wessels, Lambertus P. van den Heuvel, Lambertus P. van den Heuvel, Lambertus P. van den Heuvel, Lambertus P. van den Heuvel, Lambertus P. van den Heuvel

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Executive dysfunction relates to salience network desegregation in behavioural variant frontotemporal dementia by Melanie A. Matyi, Hamsanandini Radhakrishnan, Christopher A. Olm, Jeffrey S. Phillips, Philip A. Cook, Emma Rhodes, James C. Gee, David J. Irwin, Corey T. McMillan, Lauren Massimo

“…Given that behavioral variant frontotemporal degeneration (bvFTD) is a neurodegenerative disease associated with executive dysfunction and selective vulnerability of the salience network, we tested the hypotheses that bvFTD structural networks are de-differentiated compared to cognitively normal controls (CNC) and that network de-differentiation relates to worse executive function. Methods: In a sample of 90 patients with bvFTD and 71 age-matched CNC with diffusion MRI data we generated probabilistic tractography maps and calculated system segregation, a metric that compares within-network to between-network connectivity, to reflect the extent to which brain networks were differentiated. …”
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Prognostic Value and Therapeutic Potential of Brain-Derived Neurotrophic Factor (BDNF) in Brain Injuries (Review) by I. V. Ostrova, N. V. Golubeva, A. N. Kuzovlev, A. M. Golubev

“…Neurotrophins are proteins that play an important role in the nervous system functioning by regulating cell proliferation, differentiation, processes of neuronal survival and death, and by participating in the mechanisms of neuronal plasticity. …”
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Human immunodeficiency virus accelerates brain aging and disrupts the trajectory of glymphatic clearance in aging brain by Benedictor Alexander Nguchu, Benedictor Alexander Nguchu, Jing Zhao, Yu Lu, Yifei Han, Han Jin, Xiaoxiao Wang, Hongjun Li, Peter Shaw

“…Our data also show that increased brain-PAD in brain regions was associated with lower performance in motor and executive functions. …”
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Liver Disease and Central Nervous System Dysfunction: Linking the Two - A Narrative Review by Maciej Tenderenda, Bartosz Buczkowski, Piotr Oleksy, Agnieszka Klecza, Aleksandra Broniak, Magdalena Reclik, Karol Zieliński, Aarushi Chourasia, Krzysztof Nowakowski, Martyna Chraścina

“…HE, a potentially reversible condition, results from the accumulation of toxins, particularly ammonia, which a diseased liver fails to detoxify, affecting brain function. It is commonly associated with chronic liver diseases like cirrhosis but can also occur acutely in cases of fulminant liver failure. …”
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Effect of shift work on cerebral cortical activation and functional connectivity in nurses—implications for policy maker: a fNIRS observational study by Ran An, Cheng Li, Shaolong Ai, Yuan Wu, Sha Wang, Xi Luo, Xin Li, Yanming Xu, Hongchen He, Chengqi He

“…Also, brain activation and functional connectivity during Stroop task consistently showed that working in day shift was related to decreased brain hemodynamic activities in nurses. …”
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Exercise orchestrates systemic metabolic and neuroimmune homeostasis via the brain–muscle–liver axis to slow down aging and neurodegeneration: a narrative review by Jianda Kong, Yingao Xie, Rao Fan, Qinglu Wang, Ying Luo, Panpan Dong

“…Concurrently, hepatic SIRT1 activation promotes lipid metabolism, mitigates insulin resistance, and reduces systemic inflammation, hence preserving brain energy supply. …”
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Combined MR Volumetry and T2* Relaxometry Reveals the Olfactory System as an Iron-Dependent Structure Affected by Radiation by Njenga R. Kamau, Michelle R. Tamplin, Chu-Yu Lee, Eric D. Axelson, Isabella M. Grumbach, Michael S. Petronek

“…<b>Background/Objectives:</b> Radiation therapy can often lead to structural and functional changes in the brain resulting in radiation-induced brain injury. …”
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Intervention and research progress of gut microbiota-immune-nervous system in autism spectrum disorders among students by Min Zhou, Baoming Niu, Jiarui Ma, Yukang Ge, Yanxin Han, Wenrui Wu, Changwu Yue

“…The gut microbiota can influence brain function and behavior through the gut-brain axis via the nervous system, immune system, and metabolic pathways. …”
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Ocular-cerebral immune dialogue: a new perspective and therapeutic potential of regional lymphatic systems by Yiran Wang, Pei Guo, Weihong Li, Weihong Li, Tong Li

“…The Central Nervous System (CNS), due to its unique structure and function, possesses immune privilege, which is primarily maintained through mechanisms such as the blood-brain barrier, immune cell exclusion, and neuroglial cell regulation, effectively protecting the CNS from external insults. …”
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The Role of Selected Flavonoids in Modulating Neuroinflammation in Alzheimer’s Disease: Mechanisms and Therapeutic Potential by Joanna Kruszka, Jakub Martyński, Karolina Szewczyk-Golec, Alina Woźniak, Jarosław Nuszkiewicz

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A shared spatial topography links the functional connectome correlates of cocaine use disorder and dopamine D2/3 receptor densities by Jocelyn A. Ricard, Loïc Labache, Ashlea Segal, Elvisha Dhamala, Carrisa V. Cocuzza, Grant Jones, Sarah W. Yip, Sidhant Chopra, Avram J. Holmes

“…Abstract The biological mechanisms that contribute to cocaine and other substance use disorders involve an array of cortical and subcortical systems. Prior work on the development and maintenance of substance use has largely focused on cortico-striatal circuits, with relatively less attention on alterations within and across large-scale functional brain networks, and associated aspects of the dopamine system. …”
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