A Comparison of Approaches for Segmenting the Reaching and Targeting Motion Primitives in Functional Upper Extremity Reaching Tasks by Kyle L. Jackson, Zoran Duric, Susannah M. Engdahl, Anthony C. Santago, Siddhartha Sikdar, Lynn H. Gerber

Get full text

Spatial and functional profiles distinguish target sets of Parkinson’s disease and antipsychotic drugs with different clinical effects by Kalyani B. Karunakaran, Sanjeev Jain, Darius Widera, Graeme S. Cottrell

“…However, both APD and PD target sets showed differences in mean expression levels in specific brain regions. Moreover, they showed significant enrichment for genes highly expressed in distinct adult and prenatal brain structures relative to the overall distribution of such genes among all brain-expressed genes. …”
Get full text

Changes in low-frequency fluctuations in patients with antisocial personality disorder revealed by resting-state functional MRI. by Huasheng Liu, Jian Liao, Weixiong Jiang, Wei Wang

“…Antisocial Personality Disorder (APD) is a personality disorder that is most commonly associated with the legal and criminal justice systems. The study of the brain in APD has important implications in legal contexts and in helping ensure social stability. …”
Get full text

Cannabinoids on the Brain by Andrew J. Irving, Mark G. Rae, Angela A. Coutts

“…Some of the analgesic effects of cannabinoids also appear to involve sites within the brain. These advances in our understanding of the actions of cannabinoids and the brain endocannabinoid system have led to important new insights into neuronal function which are likely to result in the development of new therapeutic strategies for the treatment of a number of key CNS disorders.…”
Get full text

Enhanced inhibitory effects of GABA on renal and hepatic function, molecular profiles, and histological changes in male albino mice by Mohammed Abdullah Ajeel, Israa A. Al-Robaiee

“…The histological changes were detected using hematoxylin and eosin histopathological examination. Liver and kidney function test were utilized to detect any functional changes. …”
Get full text

Enhancing the quality of kinesthetic motor imagery for complex motor skills through simulated muscle activation color visualization: Evidence from time-frequency and functional con... by Xiaogang Ma, Bing Shi

“…This enhancement is associated with the selective inhibition of the frontal, central, and temporal brain regions, the activation of the occipital and parietal regions within brain rhythmic activity, and increased information flow between the occipital-parietal and frontal-parietal brain regions.…”
Get full text

Interferon regulates neural stem cell function at all ages by orchestrating mTOR and cell cycle by Damian Carvajal Ibañez, Maxim Skabkin, Jooa Hooli, Santiago Cerrizuela, Manuel Göpferich, Adrien Jolly, Katrin Volk, Marc Zumwinkel, Matilde Bertolini, Gianluca Figlia, Thomas Höfer, Guenter Kramer, Simon Anders, Aurelio A Teleman, Anna Marciniak‐Czochra, Ana Martin‐Villalba

Get full text

Artificial intelligence of things for sustainable smart city brain and digital twin systems: Pioneering Environmental synergies between real-time management and predictive planning by Simon Elias Bibri, Jeffrey Huang

“…Defined by their complex functionalities and multi-layered architectures, these systems exemplify Cyber-Physical Systems of Systems (CPSoS), offering a cohesive foundation for integrating real-time operational responsiveness with strategic predictive foresight. …”
Get full text

Mesoscale functional connectivity of amygdala to the auditory and prefrontal cortex of macaque monkeys revealed by INS-fMRI by Qianbing Li, An Ping, Yuqi Feng, Bin Xu, Baorong Zhang, Anna Wang Roe, Lixia Gao, Xinjian Li

Get full text

Analysis and Quantification of Functional Regeneration of Dendrite and Axon of PVD Neuron After Laser Injury in Caenorhabditis elegans by Harjot Brar, Dikshalee Bassi, Anindya Ghosh-Roy

Get full text

DNA methylation biomarker analysis from low-survival-rate cancers based on genetic functional approaches by Yi-Hsuan Tsai, Prasenjit Mitra, David Taniar, Tun-Wen Pai, Tun-Wen Pai

Get full text

PRDM16 functions as a co-repressor in the BMP pathway to suppress neural stem cell proliferation by Li He, Jiayu Wen, Qi Dai

Get full text

The effects of Fe2O3 nanoparticles on catalytic function of human acetylcholinesterase: size and concentration role by Samaneh Rashtbari, Zahra Hassanpour Aydinlou, Leila Sadeghi

“…Introduction: Fe2O3 NPs can enter cells quickly, pass through the blood-brain barrier and interact with macromolecules. These materials are widely used in different fields, so their risk assessment is among the most critical issues. …”
Get full text

Social behavior in ASD males: The interplay between cognitive flexibility, working memory, and functional connectivity deviations by Shi Yu Chan, Jasmine Si Min Chuah, Pei Huang, Ai Peng Tan

Get full text

Hspa13 Deficiency Impaired Marginal Zone B Cells Regulatory Function and Contributed to Lupus Pathogenesis by Chen Xing, Haoran Cui, Ge Li, Xiaoling Liu, Kun Liu, Qing Wen, Xin Huang, Renxi Wang, Lun Song

Get full text

Impaired glymphatic function in relation to cumulative blood glucose exposure: A population-based cohort study by Yufan Zhang, Jing Sun, Sihui Guo, Ying Hui, Xiaoshuai Li, Jing Li, Xinyu Zhao, Pengfei Zhao, Shuohua Chen, Shouling Wu, Zhenchang Wang, Han Lv

“…Objective: The relationship between prolonged blood glucose exposure and glymphatic system function of the brain remains unknown. This study aimed to investigate the association between cumulative blood glucose levels and neuroimaging metrics associated with glymphatic function. …”
Get full text

A first-in-human application of OPM-MEG for localizing motor activity area: Compared to functional MRI by Tai Sun, Xiaohan Chi, Yuming Peng, Qianhe Zhang, Kang Liu, Yiwen Ma, Ming Ding, Nan Ji, Yang Zhang

“…Background: Accurately localizing brain motor areas is vital for protecting motor function during neurosurgical procedures. …”
Get full text

Harnessing the potential of human induced pluripotent stem cells, functional assays and machine learning for neurodevelopmental disorders by Ziqin Yang, Ziqin Yang, Nicole A. Teaney, Nicole A. Teaney, Elizabeth D. Buttermore, Elizabeth D. Buttermore, Elizabeth D. Buttermore, Mustafa Sahin, Mustafa Sahin, Mustafa Sahin, Wardiya Afshar-Saber, Wardiya Afshar-Saber

“…Neurodevelopmental disorders (NDDs) affect 4.7% of the global population and are associated with delays in brain development and a spectrum of impairments that can lead to lifelong disability and even mortality. …”
Get full text

Lysosomal dysfunction disrupts presynaptic maintenance and restoration of presynaptic function prevents neurodegeneration in lysosomal storage diseases by Irene Sambri, Rosa D'Alessio, Yulia Ezhova, Teresa Giuliano, Nicolina Cristina Sorrentino, Vincenzo Cacace, Maria De Risi, Mauro Cataldi, Lucio Annunziato, Elvira De Leonibus, Alessandro Fraldi

“…They also demonstrate that neurodegeneration in LSDs can be slowed down by re‐establishing presynaptic functions, thus identifying synapse maintenance as a novel potentially druggable target for brain treatment in LSDs.…”
Get full text

Picture: A web application for decision support in glioma surgery by Maisa N.G. van Genderen, Raymond M. Martens, Frederik Barkhof, Philip C. de Witt Hamer, Roelant S. Eijgelaar

Get full text