Showcasing the Comprehensive Understanding of Cellular Profiling and Human Neurophysiology by Deepali Jadhav, Ranjit S. Ambad

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Inducible and reversible Clock gene expression in brain using the tTA system for the study of circadian behavior. by Hee-Kyung Hong, Jason L Chong, Weimin Song, Eun Joo Song, Amira A Jyawook, Andrew C Schook, Caroline H Ko, Joseph S Takahashi

“…The rapid time course of tTA-regulated transgene expression demonstrates that the CLOCK protein is an excellent indicator for the kinetics of Dox-dependent induction/repression in the brain. Interestingly, the daily readout of circadian period in this system provides a real-time readout of the tTA transactivation state in vivo. …”
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Effects of brain renin- angiotensin system inhibition in ISIAH rats with inherited stress-induced arterial hypertension by L. O. Klimov, M. A. Ryazanova, L. A. Fedoseeva, A. L. Markel

“…It has been shown that a steady arterial pressure increase is often associated with changes in the functioning of the central (brain) RAS in various animal models of hypertensive disease and in humans. …”
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Sex hormones shape EEG-based functional connectivity in early-stage Parkinson’s disease patients by Matteo Conti, Roberta Bovenzi, Mariangela Pierantozzi, Clara Simonetta, Valerio Ferrari, Jacopo Bissacco, Rocco Cerroni, Claudio Liguori, Francesca Di Giuliano, Nicola Biagio Mercuri, Tommaso Schirinzi, Alessandro Stefani

“…However, there are no data based on EEG functional connectivity (FC). Likewise, the contribution of sex hormones on brain FC has never been evaluated. …”
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Dynamic changes in large-scale functional connectivity prior to stimulation determine performance in a multisensory task by Edgar E. Galindo-Leon, Karl J. Hollensteiner, Florian Pieper, Gerhard Engler, Guido Nolte, Andreas K. Engel

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Hippocampal dorsal CA1: Functional connectivity and role in HCN channelopathies in affective diseases and epilepsy by Tsz Wei So, Hoi Yi Choi, Haoyu Xu, Jinwei Zhu, Lei Shi, Jacque Pak Kan Ip

“…Therefore, in this review, we summarize the recent findings on the involvement of dCA1 HCN channelopathies in brain disorders after providing an outline on the neuroanatomy and functional connectivity of dCA1, and the features of HCN channels in that region. …”
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Exploring functional neurological disorder: Cultural influences and risk factors in Iranian society – A cross-sectional study by Tina Moghadam Fard, Abdol-Hossein Vahabie, MohammadAli Shokri, Mohammad Rohani, Maziar Emamikhah, Soode Tajik Esmaeeli, Seyed Amir Hassan Habibi, Fatemeh Sadat Mirfazeli

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Preserving cognitive function in patients with Alzheimer's disease: The Alzheimer's disease neuroprotection research initiative (ADNRI) by Jie Liu, Heleen vanBeusekom, Xian‐Le Bu, Gong Chen, Paulo Henrique Rosado de Castro, Xiaochun Chen, Xiaowei Chen, Andrew N. Clarkson, Tracy D. Farr, Yuhong Fu, Jianping Jia, Jukka Jolkkonen, Woojin Scott Kim, Paula Korhonen, Shen Li, Yajie Liang, Guang‐Hui Liu, Guiyou Liu, Yu‐Hui Liu, Tarja Malm, Xiaobo Mao, Joaquim Miguel Oliveira, Mike M. Modo, Pedro Ramos‐Cabrer, Karsten Ruscher, Weihong Song, Jun Wang, Xuanyue Wang, Yun Wang, Haitao Wu, Lize Xiong, Yi Yang, Keqiang Ye, Jin‐Tai Yu, Xin‐Fu Zhou, Marietta Zille, Colin L. Masters, Piotr Walczak, Johannes Boltze, Xunming Ji, Yan‐Jiang Wang

“…To attain effective treatment for AD, it is necessary to (1) conduct extensive research on various mechanisms that cause neurodegeneration, including advances in neuroimaging techniques for earlier detection and a more precise characterization of molecular events at scales ranging from cellular to the full system level; (2) identify neuroprotective intervention targets against different neurodegeneration mechanisms; and (3) discover novel and optimal combinations of neuroprotective intervention strategies to maintain cognitive function in AD patients. …”
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Structural and functional insights of ZnT1 C-terminal domain as a regulator of zinc transport by Tomer Eli Ben Yosef, Itamar Kass, Anat Shahar, Ekaterina Eremenko, Alon Monsonego, Daniel Gitler, Arie Moran, Raz Zarivach

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Neural Mechanisms and Alterations of Sweet Sensing: Insights from Functional Magnetic Resonance Imaging Studies by Tobias Long, Colette C. Milbourn, Alison Smith, Kyaw Linn Su Khin, Amanda J. Page, Iskandar Idris, Qian Yang, Richard L. Young, Sally Eldeghaidy

“…Functional magnetic resonance imaging (fMRI) has provided valuable insights into the neural mechanisms underlying sweet sensing by mapping brain responses to both lingual/oral and gastrointestinal sweet stimuli. …”
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Central mechanisms of acupuncture in relieving visceral hypersensitivity in functional gastrointestinal disorders: A narrative review by Bowen Feng, Yu Wang, Peijing Rong

“…The widespread nature of VH indicates the involvement of the central nervous system. Acupuncture mediates the signaling pathways between the gastrointestinal tract and the brain to regulate gastrointestinal function and relieve VH. …”
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RELATIONSHIPS BETWEEN THE ATTENTION NETWORK FUNCTIONING AND SPONTANEOUS EEG ACTIVITY IN PATIENTS WITH CORONARY ARTERY DISEASE by I. V. Tarasova, N. V. Volf, O. L. Barbarash

“…The cognitive decline in cardiac patients may be associated with insufficiency of the cerebral blood supply and inhibition of the brain functional state that manifested as a slowing of spontaneous EEG activity. …”
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Nasal obstruction during development leads to defective synapse elimination, hypersynchrony, and impaired cerebellar function by Moe Tanigawa, Mengke Liu, Mariko Sekiguchi, Kyosuke Goda, Chiho Kato, Takashi Ono, Naofumi Uesaka

“…Abstract Nasal respiratory disorders are linked to craniofacial anomalies and systemic dysfunctions. However, the implications of nasal respiratory disorders on brain development and their subsequent impact on brain functionalization remain largely unknown. …”
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Do β-Defensins and Other Antimicrobial Peptides Play a Role in Neuroimmune Function and Neurodegeneration? by Wesley M. Williams, Rudy J. Castellani, Aaron Weinberg, George Perry, Mark A. Smith

“…It is widely accepted that the brain responds to mechanical trauma and development of most neurodegenerative diseases with an inflammatory sequelae that was once thought exclusive to systemic immunity. …”
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Light-regulated voltage-gated potassium channels for acute interrogation of channel function in neurons and behavior. by Henry H Jerng, Jay M Patel, Tamor A Khan, Benjamin R Arenkiel, Paul J Pfaffinger

“…In summary, we have developed novel photoactivatable Kv channels that provide new ways to interrogate neural circuits in vivo and to examine the roles of normal and disease-causing mutant Kv channels in brain function and behavior.…”
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Insights and progress on the biosynthesis, metabolism, and physiological functions of gamma-aminobutyric acid (GABA): a review by Qingli Zhang, Lei Zhu, Hailong Li, Qu Chen, Nan Li, Jiansheng Li, Zichu Zhao, Di Xiao, Tingting Tang, Chunhua Bi, Yan Zhang, Haili Zhang, Guizhen Zhang, Mingyang Li, Yanli Zhu, Jingjing Zhang, Jingjing Kong

“…In mammals, it influences physiological functions such as nervous system regulation, blood pressure equilibrium, liver and kidneys enhancement, hormone secretion regulation, immunity enhancement, cancer prevention, as well as anti-aging effects. …”
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Simplified cerebellum-like spiking neural network as short-range timing function for the talking robot by Vo Nhu Thanh, Hideyuki Sawada

“…In human speech, the timing function is important for determining its duration, stress and rhythm; however, little attention has been paid to these issues when building a speech synthesis system. …”
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The developmental regulator Pax6 is essential for maintenance of islet cell function in the adult mouse pancreas. by Alan W Hart, Sebastien Mella, Jacek Mendrychowski, Veronica van Heyningen, Dirk A Kleinjan

“…The transcription factor Pax6 is a developmental regulator with a crucial role in development of the eye, brain, and olfactory system. Pax6 is also required for correct development of the endocrine pancreas and specification of hormone producing endocrine cell types. …”
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Endogenous IL-1 in cognitive function and anxiety: a study in IL-1RI-/- mice. by Carol L Murray, Pauline Obiang, David Bannerman, Colm Cunningham

“…The results argue for a careful evaluation of the roles of endogenous IL-1 in hippocampal and limbic system function.…”
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Neuronal guidance signaling in neurodegenerative diseases: Key regulators that function at neuron-glia and neuroimmune interfaces by Junichi Yuasa-Kawada, Mariko Kinoshita-Kawada, Masaki Hiramoto, Satoru Yamagishi, Takayasu Mishima, Shin’ichiro Yasunaga, Yoshio Tsuboi, Nobutaka Hattori, Jane Y. Wu

“…This suggests that neuronal guidance pathways are critical not only for neural wiring but also for ongoing function and maintenance of the mature nervous system. …”
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