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Non-invasive arterial input function estimation using an MRA atlas and machine learning
Published 2025-05-01“…Abstract Background Quantifying biological parameters of interest through dynamic positron emission tomography (PET) requires an arterial input function (AIF) conventionally obtained from arterial blood samples. …”
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502
Evaluation of novel computerized tomography scoring systems in human traumatic brain injury: An observational, multicenter study.
Published 2017-08-01“…<h4>Background</h4>Traumatic brain injury (TBI) is a major contributor to morbidity and mortality. …”
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503
EnSLDe: an enhanced short-range and long-range dependent system for brain tumor classification
Published 2025-04-01“…IntroductionBrain tumors pose significant harm to the functionality of the human nervous system. …”
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504
Photoacoustic detecting of brain lymphatic dysfunction in inflammatory models
Published 2025-09-01“…In this study, we employed dual-contrast functional photoacoustic microscopy to evaluate the impact of lipopolysaccharide-induced central nervous system inflammation on brain lymphatic function and to explore the protective effects of the P2X7 receptor (P2X7R) antagonist. …”
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505
Functional connectivity across multi-frequency bands in patients with tension-type headache: a resting-state fMRI retrospective study
Published 2025-05-01“…Abstract Objectives Tension-type headache (TTH) is the most common nervous system disorder worldwide. This study aimed to examine abnormal network-level brain functional connectivity (FC) alterations in patients with TTH across multi-frequency bands. …”
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506
Functional Decoupling of Emotion Coping Network Subsides Automatic Emotion Regulation by Implementation Intention
Published 2021-01-01“…To investigate the neural changes at AER, we collected functional MRI (fMRI) in 31 participants who attended to neutral and disgust pictures in three conditions: watching, goal intention (GI), and reappraisal by implementation intention (RII). …”
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507
A functional screen uncovers circular RNAs regulating excitatory synaptogenesis in hippocampal neurons
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Running therapy improves clinical symptoms but not functional network connectivity in individuals with affective disorders
Published 2025-01-01“…Conclusion: We conclude that there were either no functional abnormalities to improve or the effects of 16 weeks running therapy may be too subtle to impact (global) network communication of functional systems and may be limited to changes in localized brain regions. …”
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Enhancing Effects of Lactobacillus brevis CQPC12 on Motor Function in Mice Damaged by Antibiotics
Published 2025-01-01“…This study aims to investigate the potential anti-inflammatory and antioxidant properties of Lactobacillus brevis CQPC12 (LBCQPC12) to enhance brain, neural, and motor functioning in mice. Mice were given intraperitoneal injections of mixed antibiotics (5 mg/mL neomycin, 25 mg/mL vancomycin, 0.1 mg/mL amphotericin B, 10 mg/mL ampicillin, 5 mg/mL metronidazole, and 1.5 μg/mL lipopolysaccharide) to mimic human bodies. …”
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511
Poop for thought: Can fecal microbiome transplantation improve cognitive function in aging dogs?
Published 2025-02-01“…The gastrointestinal system is in constant communication with the brain via several conduits collectively termed the gut-brain axis. …”
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512
Molecular, physiological and functional features underlying antipsychotic medication use related cortical thinning
Published 2025-04-01“…Here, we investigated potential mechanisms across multiple levels of description by comparing antipsychotic medication related cortical thinning to atlases of normative neurotransmitter distributions, structural and functional organization of the brain, and meta-analyses of functional activation from the Neurosynth database. …”
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513
Network Analysis of Functional Genomics Data: Application to Avian Sex-Biased Gene Expression
Published 2012-01-01“…To address this shortcoming we propose a number of network-based analyses that give additional functional insights into the studied process. These were applied to a dataset of sex-specific gene expression in the chicken gonad and brain at different developmental stages. …”
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Redox Regulation of Protein Function via Cysteine S-Nitrosylation and Its Relevance to Neurodegenerative Diseases
Published 2012-01-01“…In contrast, under pathological conditions, there is a pronounced increase in ROS/RNS generation, impairing normal neurological function. Nitric oxide (NO) is one such molecule that functions as a signaling agent under physiological conditions but causes nitrosative stress under pathological conditions due to its enhanced production. …”
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516
Speech and Music Acoustics, Rhythms of the Brain and their Impact on the Ability to Accept Information
Published 2020-03-01“…If the neural network is an “antenna” that captures thoughts, and its “adjustment” at the physical level can be carried out (and is carried out) through sensory systems (including the hearing organ), the study of the frequency structure of speech will answer a number of important questions, including including related and higher brain functions (insight, creativity). …”
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517
Mitochondrial respiration atlas reveals differential changes in mitochondrial function across sex and age
Published 2024-12-01“…Altogether, our data provide the most comprehensive compendium of mitochondrial respiration and illuminate functional signatures of aging across diverse tissues and organ systems.…”
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518
Proinflammatory cytokines, oxidative stress, and organ function as biomarkers of soman (GD) chronic neurotoxicity
Published 2025-03-01“…This study identifies critical chronic biomarkers of soman exposure affecting the brain, serum, CSF, liver, and kidney. The findings highlight the critical need to monitor systemic and neurological impacts, as well as organ function, to develop effective diagnostic and therapeutic strategies for survivors of nerve agent exposure or OP pesticide poisoning. …”
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Metabolic disturbances and endothelial function in elderly patients with systolic and diastolic chronic heart failure
Published 2009-10-01“…To study the associations between metabolic disturbances, cytokine levels, brain natriuretic peptide (BNP), and endothelial function markers in elderly patients with various types of chronic heart failure (CHF).Material and methods. …”
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The effect of Polybrominated diphenyl ethers at the fetal blood-brain-barrier: evaluation using a microphysiological system
Published 2025-03-01“…This study evaluated the effect of environmental pollutant and flame retardant, Polybrominated Diphenyl Ethers (PBDE) 99 and 47, on cell viability, glutamate dysregulation, and neuroinflammation using a microphysiologic system (MPS) of human fetal blood-brain-barrier organ on a chip (FB-OOC).MethodsThe FB-OOC is composed of 3-cell culture chambers, connected by microchannels, containing 1) human brain microvessel endothelial cells (HBMEC), 2) human vascular pericytes (HBVP), and 3) a triculture of neurons, astrocytes, and microglia in a 5:2:1 ratio, respectively. …”
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