Suggested Topics within your search.
Suggested Topics within your search.
-
2221
Case Report: Adverse reaction to butorphanol in a Collie homozygous for the ABCB1-1∆ (MDR1) mutation
Published 2025-05-01“…Certain dog breeds, particularly herding breeds like Collies, are predisposed to drug sensitivity due to the ABCB1-1∆ (previously known as MDR1) mutation, which disrupts P-glycoprotein (P-gp) function. This mutation impairs drug efflux at the blood–brain barrier, leading to increased susceptibility to neurotoxic effects. …”
Get full text
Article -
2222
Replication of neural responses to monetary incentives and exploration of reward-influenced network connectivity in fibromyalgia
Published 2022-12-01“…Neuroimaging research has begun to implicate alterations of brain reward systems in chronic pain. Previously, using functional magnetic resonance imaging (fMRI) and a monetary incentive delay (MID) task, Martucci et al. (2018) showed that neural responses to reward anticipation and outcome are altered in fibromyalgia. …”
Get full text
Article -
2223
-
2224
Thrombosis, Neuroinflammation, and Poststroke Infection: The Multifaceted Role of Neutrophils in Stroke
Published 2017-01-01“…Because infections are known to impair the clinical course of stroke, therapeutic interventions that target neutrophils should preserve or even restore their function outside the central nervous system (CNS). …”
Get full text
Article -
2225
-
2226
Longitudinal changes in striatocortical connectivity in first-episode psychosis associated with the emergence of treatment resistance
Published 2025-08-01“…Compared to healthy controls, participants with treatment-responsive psychosis presented baseline differences in functional connectivity of ventral striatal systems, without changes over time; whereas patients with treatment-resistant psychosis showed both baseline and longitudinal differences in ventral striatal systems, compared to healthy controls. …”
Get full text
Article -
2227
Astrocyte priming enhances microglial Aβ clearance and is compromised by APOE4
Published 2025-08-01“…While well-characterized in peripheral immunity, its function in brain-resident cells such as astrocytes under non-disease conditions remains unclear. …”
Get full text
Article -
2228
What is neuroplasticity? Why it is important?: Types and its basic mechanisms
Published 2021-04-01“…The human brain is interconnected in a plastic manner to form functional brain net-works. …”
Get full text
Article -
2229
Motor Neuron Disease: The Contribution of TAR-43 Gene in Amyotrophic Lateral Sclerosis
Published 2023-08-01“…Hyperphosphorylated and ubiquitinated TDP-43 deposits function as inclusion bodies in the brain and spinal cord which causes ALS. …”
Get full text
Article -
2230
Interactive Medical Image Segmentation using Active Contour with Improved F Energy in Level-Set Tuning
Published 2022-06-01“…The system was evaluated using 160 medical images from two databases, including 80 mammograms and 80 MRI brain scans. …”
Get full text
Article -
2231
MULTIDISCIPLINARY APPROACH TO THE CORRECTION OF ACCOMMODATION REFRACTION DISORDERS IN VISUALLY INTENSIVE LABOR PERSONS
Published 2015-07-01“…Accommodation disorders are accompanied by changes in ciliary muscle blood supply, abnormalities of vegetative segment regulation, parasympathetic brain vascular dystonia due to the decreased tonus of sympathetic nervous system. …”
Get full text
Article -
2232
-
2233
Peroxisome dynamics and inter-organelle interactions in neuronal health and disease
Published 2025-06-01“…Finally, the review outlines the current knowledge gaps relating to the mechanisms by which peroxisome dynamics and inter-organelle interactions influence neuronal (dys)function, proposing potential new research directions to address these and further our understanding of the multi-faceted roles peroxisomes play in brain health and disease.…”
Get full text
Article -
2234
Antiageing strategy for neurodegenerative diseases: from mechanisms to clinical advances
Published 2025-03-01“…Thus, we aim to elucidate the role of ageing in neurodegenerative diseases from the perspective of a complex system, in which the brain is the core and peripheral organs and tissues form a holistic network to support brain functions. …”
Get full text
Article -
2235
The Treatment of ADHD in Adults: Efficacy and Safety of Stimulants and Non-Stimulants
Published 2025-07-01“…It is associated with brain structural and functional abnormalities, particularly in areas linked to executive functions, such as the prefrontal cortex and cerebellum. …”
Get full text
Article -
2236
PF4 in rejuvenation therapy: neuroprotection and cognitive enhancement
Published 2025-04-01“…Systemic administration of exogenous PF4 has been shown to reduce circulating pro-aging immune factors and restore peripheral immune function in the aged brain by mitigating age-related hippocampal neuroinflammation, promoting molecular changes in synaptic plasticity, and improving cognitive function in aged mice. …”
Get full text
Article -
2237
What is the Role of Testosterone Therapy in Postmenopausal Women? A SWOT Analysis
Published 2023-08-01“…It influences cognitive functions such as memory, processing speed, and executive function through androgen receptor-regulated regions of the brain. …”
Get full text
Article -
2238
PERK activation mitigates tau pathology in vitro and in vivo
Published 2017-02-01Get full text
Article -
2239
Dopaminergic Modulation of Medial Prefrontal Cortex Deactivation in Parkinson Depression
Published 2015-01-01“…DMN activity is negatively correlated with activity in brain systems used for external visual attention. …”
Get full text
Article -
2240
CHIVID: A Rapid Deployment of Community and Home Isolation During COVID-19 Pandemics
Published 2024-01-01Get full text
Article