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2101
Facilitating cognitive neuroscience research with 80-sensor optically pumped magnetometer magnetoencephalography (OPM-MEG)
Published 2025-05-01“…For resting-state recordings, the two modalities exhibit similar power distributions, functional connectomes, and microstate clusters. These findings indicate that the 80-sensor OPM-MEG system provides spatial and temporal characteristics comparable to those of traditional SQUID-MEG. …”
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Glymphatic inhibition exacerbates tau propagation in an Alzheimer’s disease model
Published 2024-04-01“…The glymphatic system, a brain-wide pathway responsible for clearing extracellular metabolic waste from the central nervous system, has gained attention as a promising target for removing these toxic proteins. …”
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2105
Gene delivery of a modified antibody to Aβ reduces progression of murine Alzheimer's disease.
Published 2019-01-01“…The Fc region mediates effector function and enhances antigen clearance from the brain by neonatal Fc receptor (FcRn)-mediated reverse transcytosis and is therefore desirable to include for such treatments. …”
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DNA nanomachine‐driven chemodynamic therapy against glioblastoma
Published 2024-12-01“…Additionally, Cu@tFNAs‐G‐A NM was found to be rapidly cleared from the brain and normal tissues within 24 h, minimizing potential systemic toxic side effects. …”
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Synaptic plasticity facilitates oscillations in a V1 cortical column model with multiple interneuron types
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2110
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Contemporary insights into neuroimmune interactions across development and aging
Published 2025-07-01“…Initially considered distinct systems with independent physiological functions, recent evidence highlights the crucial role of active crosstalk between the nervous and immune systems in regulating critical physiological and neurological processes and immunological homeostasis. …”
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2112
Genome-wide divergence of DNA methylation marks in cerebral and cerebellar cortices.
Published 2010-06-01“…<h4>Background</h4>Emerging evidence suggests that DNA methylation plays an expansive role in the central nervous system (CNS). Large-scale whole genome DNA methylation profiling of the normal human brain offers tremendous potential in understanding the role of DNA methylation in brain development and function.…”
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2113
Neural representation of sensorimotor features in language-motor areas during auditory and visual perception
Published 2025-01-01“…Abstract Speech processing involves a complex interplay between sensory and motor systems in the brain, essential for early language development. …”
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2114
The role of alpha-synuclein in synucleinopathy: Impact on lipid regulation at mitochondria–ER membranes
Published 2025-04-01“…In the present study, we analyzed the lipid composition of postmortem human samples, focusing on the substantia nigra pars compacta of Parkinson’s disease and controls, as well as three less affected brain regions of Parkinson’s donors. To further assess synucleinopathy-related lipidome alterations, similar analyses were performed on the striatum of multiple system atrophy cases. …”
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In vitro models of microglia: a comparative study
Published 2025-05-01“…Abstract Microglia perform key homeostatic functions to protect the central nervous system (CNS). …”
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2116
Information Integration from Distributed Threshold-Based Interactions
Published 2017-01-01“…This simple model abstracts some of the essential characteristics of several artificial intelligence systems and of biological systems epitomized by the brain. …”
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2117
Mechanism of Transcranial Magnetic Stimulation Therapy for Neuropathic Pain
Published 2024-12-01“…This study reviews the neurobiological mechanisms of TMS in alleviating NP from the aspects of regulation of synaptic plasticity, functional reorganization of neural network (inducing cortical-cortical functional connectivity and subcortical brain region functional connectivity), sensitivity of afferent nerve fibers, neurotransmitter levels and neuroimmunity based on the mechanism of TMS, in order to provide a basis for the treatment of NP by TMS. …”
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Bridging molecular and cellular neuroscience with proximity labeling technologies
Published 2025-07-01“…By integrating PL with cutting-edge multi-omics strategies and advanced imaging technologies, researchers can decode the intricate interplay between structural and functional neural networks. As PL technologies continue to evolve, they bridge molecular and cellular neuroscience, offering a useful framework for unraveling the complexity of brain networks. …”
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2119
Potential Target Receptors for the Pharmacotherapy of Burning Mouth Syndrome
Published 2025-06-01“…Furthermore, the altered processing of pain and reward, which is a key feature of chronic pain, implicates the brain’s dopaminergic system. A decrease in dopamine D2 receptor function within this system is believed to contribute to the pathology of BMS. …”
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Impact of Polymorphic Microfibers for Establishment of Neuronal Model
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