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2081
Low-intensive Laser Therapy for Management of Cerebral Dysfunction in Patients with Obstructive Jaundice of Non-tumor Origin
Published 2019-04-01“…BACKGROUND The liver’s function is impaired above all others in the mechanical jaundice, which leads to the progression of endogenous intoxication and the damage of different organs and systems, including the brain. …”
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2082
Interaction between corticotropin-releasing factor, orexin, and dynorphin in the infralimbic cortex may mediate exacerbated alcohol-seeking behavior
Published 2024-11-01“…As individuals transition to alcohol dependence, compensatory allostatic mechanisms result in insults to hypothalamic-pituitary-adrenal axis function, mediated by corticotropin-releasing factor (CRF), which is subsequently hypothesized to alter brain reward pathways, influence affect, elicit craving, and ultimately perpetuate problematic drinking and relapse vulnerability. …”
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2083
The therapeutic effects and mechanisms of glucagon-like peptide-1 receptor agonists in neurocognitive disorders
Published 2025-04-01“…Furthermore, GLP-1R activity is modulated by gut microbiota composition and short-chain fatty acid abundance, implicating the gut–brain axis in its regulatory influence on neurological function. …”
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2084
Modulatory effect of levodopa on the basal ganglia-cerebellum connectivity in Parkinson’s disease
Published 2025-05-01“…Eigenvector Centrality Mapping (ECM) further identified functional hubs, with cerebellar hubs being the only ones within the cortico-basal ganglia-cerebellum system affected by medication. …”
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2085
Effects and mechanisms of supramaximal high-intensity interval training on extrapulmonary manifestations in people with and without chronic obstructive pulmonary disease (COPD-HIIT...
Published 2024-10-01“…Key secondary outcomes include change from baseline exercise tolerance, brain structure, and function measured by MRI, neuroinflammation measured by PET/CT, systemic inflammation, and intramuscular adaptations. …”
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2086
Valproate Damaging Effect on Erythrocyte Metabolism as a Decisive Factor in the Development of Encephalopathy
Published 2025-04-01“…Methods: To determine whether different therapeutic VPA doses affect major metabolic pathways in rat erythrocytes, the activity of rate-limiting enzymes and levels of metabolites of glycolysis, the Rapoport–Luebering shunt, the pentose phosphate pathway and the antioxidant systems were measured. Results: Our data showed that VPA-induced G6PD inhibition leads to profound oxidative stress, increased MetHb formation and decreased 2,3-DPG and ATP levels in erythrocytes that underlie the loss of their oxygen transport function, thus being a cause of a brain energy crisis that precedes encephalopathy. …”
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2087
Advancements in the investigation of gut microbiota-based strategies for stroke prevention and treatment
Published 2025-03-01“…Recent advancements have elucidated the microbiota-gut-brain axis (MGBA), underscoring the complex interplay between gut health and brain function. …”
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2088
Mamba with split-based pyramidal convolution and Kolmogorov-Arnold network-channel-spatial attention for electroencephalogram classification
Published 2025-04-01“…KSA-Mamba-PySPConv promises to be an effective tool in electroencephalogram classification in brain–computer interface systems.…”
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2089
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2090
Motor Improvement-Related Regional Cerebral Blood Flow Changes in Parkinson’s Disease in Response to Antiparkinsonian Drugs
Published 2019-01-01“…Single-photon emission computed tomography (SPECT) measurement of cerebral blood flow allows evaluation of temporal changes in brain function, and using SPECT, we aimed to identify motor improvement-related rCBF changes in response to the administration of antiparkinsonian drugs. …”
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2091
Correction of gut microbiota disorders in anxiety and depressive disorders
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2092
Neuropsychology of epilepsy surgery and theory-based practice: an opinion review
Published 2023-09-01“…As to epilepsy, the logic of cognitive functions organized into complex functional systems, contrary to modular views of the brain, heralds current knowledge of epilepsy as a network disease, as well as the concept of the functional deficit zone.…”
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2093
Multimodal closed-loop strategies for gait recovery after spinal cord injury and stroke via the integration of robotics and neuromodulation
Published 2025-07-01“…This narrative review emphasizes the importance of mobile brain/body imaging (MoBI) for guiding the development of closed-loop systems that integrate volitional brain signals with residual motor activity in stroke and spinal cord injury patients. …”
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2094
Enhancing anti-EGFRvIII CAR T cell therapy against glioblastoma with a paracrine SIRPγ-derived CD47 blocker
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2095
Visualization and workload with implicit fNIRS-based BCI: toward a real-time memory prosthesis with fNIRS
Published 2025-05-01“…Functional Near-Infrared Spectroscopy (fNIRS) has proven in recent time to be a reliable workload-detection tool, usable in real-time implicit Brain-Computer Interfaces. …”
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2096
Muscarinic acetylcholine receptor activated effectors in principal neurons of the rat basolateral amygdala
Published 2025-07-01“…Improved understanding of these effectors will provide potentially valuable new insights on the wide range of mechanisms through which cholinergic system dysfunction can lead to impaired executive function.…”
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2097
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2098
Next generation bioelectronic medicine: making the case for non-invasive closed-loop autonomic neuromodulation
Published 2025-01-01“…Today, invasive or non-invasive closed-loop systems have yet to be developed that dynamically modulate autonomic nervous system function by responding to real-time physiological and molecular signals; it represents a transformative approach to therapeutic interventions and major opportunity by which the bioelectronic field may advance. …”
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2099
EEG-Based Inverse Reinforcement Learning for Safety-Oriented Global Path Planning in Dynamic Environments
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2100
CRABP1 Signalosomes in Non-Canonical Actions of Retinoic Acid—Maintaining Health and Preventing Thyroid Dysfunction in Aging
Published 2025-06-01“…This underscores the clinical relevance of CRABP1 signalosomes in maintaining health and the functions of certain cells/organ systems, especially in the thyroid and during the aging process. …”
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