Sea Cucumber Hydrolysates Alleviate Cognitive Deficits in D-Galactose-Induced C57BL/6J Aging Mice Associated with Modulation of Gut Microbiota by Han Gong, Hang Zhao, Xueying Mao

“…The effects of SCH on behavior, hippocampal morphology, gut microbiota, hippocampal cholinergic system, brain-derived neurotrophic factor (BDNF) signaling, and neuroinflammatory pathways were investigated. …”
Get full text

Crossing nerve transfer restores limb movement by reorganizing the cortico-rubro-spinal pathway in peripheral nerve injury by Zhen Pang, Yunuo Chen, Chuanjun Tong, Yiming Chen, Gaowei Lei, Zeyu Cai, Shuai Zhu, Yundong Shen, Zhifeng Liang, Jiayi Zhang, Fang Huang, Yuqiu Zhang, Changlong Hu, Lei Xue, Xiaohui Zhang, Fei Wang, Wendong Xu

“…Summary: Peripheral nerves connect the central nervous system to the limbs. Crossing nerve transfer (CNT) promotes motor recovery after unilateral brain injury by inducing functional reorganization in central neural circuits. …”
Get full text

A Narrative Review of Neuroimaging Studies in Acupuncture for Migraine by Peihong Ma, Xiaohui Dong, Yuzhu Qu, Zhaoxuan He, Tao Yin, Shirui Cheng, Zilei Tian, Yuke Teng, Kunnan Xie, Ruirui Sun, Siyi Yu, Fang Zeng

Get full text

Sex, senescence, senolytics, and cognition by Thomas C. Foster, Thomas C. Foster, Ashok Kumar

“…Interventions that remove senescent cells, such as senolytic drugs, can reduce or ameliorate some of the aging-related loss of function. Similarities and differences in senolytic responses of males and females depend on the system examined, the treatment regimen, the level of senescent cell burden, and the age when treatment is initiated. …”
Get full text

Autism-Associated PTCHD1 Missense Variants Bind to the SNARE-Associated Protein SNAPIN but Exhibit Impaired Subcellular Trafficking by Stephen F. Pastore, Connie T.Y. Xie, Roya Derwish, Tahir Muhammad, Tereza Blahova, Sierra C. El-masri, Paul W. Frankland, Paul A. Hamel, John B. Vincent

“…Background: PTCHD1 is a susceptibility gene for autism spectrum disorder and intellectual disability. Its function in brain development and neurotransmission remains elusive. …”
Get full text

Possible Potentiating Effects of Combined Administration of Alcohol, Caffeine, and Nicotine on In Vivo Dopamine Release in Addiction-Related Circuits Within the CNS of Rats by Carmen Costas-Ferreira, Martiño Barreiro-Chapela, Rafael Durán, Lilian R. Ferreira Faro

Get full text

Analysis of the neuromuscular deficits caused by STAM1 deficiency by John W. McLean, Mary VanHart, Madilyn P. McWilliams, Charlene B. Farmer, David K. Crossman, Rita M. Cowell, Julie A. Wilson, Scott M. Wilson

Get full text

Human dorsal forebrain organoids show differentiation-state-specific protein secretion by Zeynep Yentür, Theresa Kagermeier, Kseniia Sarieva, Mohamed A. Jarboui, Katharina Becker, Simone Mayer

Get full text

Melatonin - A Cutaneous Perspective by Tapan Dhali, Mona Sharma, Priyanka Hemrajani

“…The primary function of melatonin is to regulate sleep-wake cycles. …”
Get full text

Melatonin - A Cutaneous Perspective by Tapan Dhali, Mona Sharma, Priyanka Hemrajani

“…The primary function of melatonin is to regulate sleep-wake cycles. …”
Get full text

DICOM datasets for reproducible neuroimaging research across manufacturers and software versions by Christopher Rorden, Benoît Béranger, Hu Cheng, Matthew Clemence, Clément Debacker, Brice Fernandez, Yaroslav O. Halchenko, Michael P. Harms, Bharath Holla, Isaiah Innis, Joost P. A. Kuijer, Daniel Levitas, Krisanne Litinas, Jeffrey Luci, Roger Newman-Norlund, Scott Peltier, Wolfgang Rehwald, Robert I. Reid, Baxter Rogers, Christopher G. Schwarz, Jaemin Shin, Venkatasubramanian Ganesan, Sandeep Ganji, Paul S. Morgan

Get full text

Understanding dysbiosis and resilience in the human gut microbiome: biomarkers, interventions, and challenges by Azadeh Safarchi, Azadeh Safarchi, Ghanyah Al-Qadami, Ghanyah Al-Qadami, Cuong D. Tran, Michael Conlon

Get full text

Zebrafish Suppressor of Cytokine Signaling 4b (Socs4b) Is Dispensable for Development but May Regulate Epidermal Growth Factor Receptor Signaling by Monique Trengove, Parisa Rasighaemi, Clifford Liongue, Alister C. Ward

“…Zebrafish possess two <i>SOCS4</i> paralogues, with <i>socs4a</i> previously shown to participate in central nervous system development and function. This study examined the role of the other paralogue, <i>socs4b</i>, through expression analysis and functional investigations in vivo and in vitro. …”
Get full text

Neural networks with optimized single-neuron adaptation uncover biologically plausible regularization. by Victor Geadah, Stefan Horoi, Giancarlo Kerg, Guy Wolf, Guillaume Lajoie

“…Yet, it is still unclear how brain circuits exploit single-neuron flexibility, and how network-level requirements may have shaped such cellular function. …”
Get full text

Designed optogenetic tool for bridging single-neuronal multimodal information in intact animals by Rong-Kun Tao, Le Sun, Yu Qian, Yi-Ming Huang, Yu-Han Chen, Chun-Yu Guan, Ming-Cang Wang, Yi-Di Sun, Jiu-Lin Du

“…Abstract Integrating morphological, functional and molecular information of individual neurons is critical for classifying neuronal cell types and probing circuit mechanisms of brain functions. …”
Get full text

On the Potential of a New Generation of Magnetometers for MEG: A Beamformer Simulation Study. by Elena Boto, Richard Bowtell, Peter Krüger, T Mark Fromhold, Peter G Morris, Sofie S Meyer, Gareth R Barnes, Matthew J Brookes

“…Magnetoencephalography (MEG) is a sophisticated tool which yields rich information on the spatial, spectral and temporal signatures of human brain function. Despite unique potential, MEG is limited by a low signal-to-noise ratio (SNR) which is caused by both the inherently small magnetic fields generated by the brain, and the scalp-to-sensor distance. …”
Get full text

NeuroScale: evolutional scale-based protein language models enable prediction of neuropeptides by Hongqi Zhang, Shanghua Liu, Wei Su, Xueqin Xie, Junwen Yu, Fuying Dao, Mi Yang, Hao Lyu, Hao Lin

Get full text

The Perception and Endogenous Modulation of Pain by Michael H. Ossipov

“…Brain imaging studies revealed a “pain matrix,” consisting of cortical and subcortical regions that respond to noxious inputs and can positively or negatively modulate pain through activation of descending pain modulatory systems. …”
Get full text

From Molecules to Mind: The Critical Role of Chitosan, Collagen, Alginate, and Other Biopolymers in Neuroprotection and Neurodegeneration by Weronika Kruczkowska, Julia Gałęziewska, Katarzyna Helena Grabowska, Piotr Gromek, Karolina Czajkowska, Maciej Rybicki, Mateusz Kciuk, Karol Kamil Kłosiński

Get full text

The histological development of the fetal human inferior colliculus during the second trimester by Reetuparna Nanda, Mihail Bota, Jaikishan Jayakumar, Jaikishan Jayakumar, Suresh S, S. Lata, E. Harish Kumar, Chitra Srinivasan, Sudha Vasudevan, Kumutha Jayaraman, Mohanasankar Sivaprakasam, Mohanasankar Sivaprakasam, Mohanasankar Sivaprakasam, Richa Verma

Get full text