Showing 1,021 - 1,040 results of 3,415 for search '(functional OR function) alignment', query time: 0.15s Refine Results
  1. 1021
  2. 1022

    Patient-centered assessment of treatment for alpha-1 antitrypsin deficiency: literature review to identify concepts and measures for people with alpha1-antitrypsin deficiency by Ekin Seçinti, Karolina Schantz, Laure Delbecque, John Krege, Rikki Mangrum, Sarah E. Curtis

    Published 2025-02-01
    “…A limited number of PROMs have been used in research on AATD or in clinical trials of treatment, including COPD-specific measures that assess symptoms and quality of life and measures of mood, sleep, and general physical and psychosocial functioning. The current study documented the available evidence and compiled a list of potential concepts of interest, but further qualitative and quantitative studies will be needed to understand the outcomes that matter to people with AATD and to evaluate the alignment between these outcomes and available measures.…”
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  3. 1023

    mNSF: multi-sample non-negative spatial factorization by Yi Wang, Kyla Woyshner, Chaichontat Sriworarat, Genevieve Stein-O’Brien, Loyal A. Goff, Kasper D. Hansen

    Published 2025-06-01
    “…Through simulations and real data analysis, we demonstrate mNSF’s efficacy in identifying true factors, shared anatomical regions, and region-specific biological functions. mNSF’s performance is comparable to alignment-based methods when alignment is feasible, while enabling analysis in scenarios where spatial alignment is unfeasible. mNSF shows promise as a robust method for analyzing spatially resolved transcriptomics data across multiple samples.…”
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    Article
  4. 1024

    Ab initio mechanisms and design principles for photodesorption from TiO2 by Aaron R. Altman, Felipe H. da Jornada

    Published 2025-05-01
    “…These results, not qualitatively captured by constrained density-functional theory, highlight how MBPT calculations can inform photocatalytic reaction design.…”
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    Article
  5. 1025

    Understanding dimensions of trust in AI through quantitative cognition: Implications for human-AI collaboration. by Weizheng Jiang, Dongqin Li, Chun Liu

    Published 2025-01-01
    “…The findings reveal a dual effect of trust in AI on cognition: while functional and emotional trust enhance higher-order cognition, the transparency dimension of cognitive trust inhibits cognitive processes. …”
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    Article
  6. 1026

    Impact of Microdosimetric Modeling on Computation of Relative Biological Effectiveness for Carbon Ion Radiotherapy by Shannon Hartzell, Keith M. Furutani, Alessio Parisi, Tatsuhiko Sato, Yuki Kase, Christian Deglow, Thomas Friedrich, Chris J. Beltran

    Published 2025-06-01
    “…Parameter optimization within the mMKM enables alignment across models. Our findings emphasize that microdosimetric function and domain geometry selection must be explicitly accounted for in microdosimetry-based RBE modeling, and that model parameters must be tuned accordingly to ensure consistent and biologically accurate predictions.…”
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  7. 1027

    Does robotic arm-assisted total knee arthroplasty have a role to play in large deformities? by Vermorel Pierre-Henri, Ciccullo Carlo, De Berardinis Luca, Gigante Antonio Pompilo, Neri Thomas, Philippot Rémi

    Published 2024-01-01
    “…Background: Total knee arthroplasty (TKA) for patients with a large preoperative deformity (more than 10° varus or valgus) remains a challenge leading to a high rate of outliers, unsatisfactory functional results, or early prosthetic loosening. Robotic arm-assisted TKA (RATKA) has shown improvements in implant positioning accuracy. …”
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    Article
  8. 1028

    Development of Digital Training Twins in the Aircraft Maintenance Ecosystem by Igor Kabashkin

    Published 2025-07-01
    “…The proposed system dynamically evaluates learner skill gaps and assigns individualized training resources through a multi-objective optimization function that balances skill alignment, Bloom’s cognitive level, fidelity tier, and time efficiency. …”
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  9. 1029

    Cloning and analysis of eight tomato ACE full-length cDNA sequences by SONG Xiao-yi, XU You-ping, ZHANG Zhi-xin, XU Qiu-fang, CAI Xin-zhong

    Published 2009-05-01
    “…To further analysis the function of these ACE genes in disease resistance, full-length cDNA sequences of 8 ACE fragments, including ACE13, ACE14, ACE19, ACE25, ACE29, ACE36, ACE39 and ACE112, were cloned by employing RACE technique. …”
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  10. 1030

    A Fused Multiscale Pictorial Sequence Learning Mechanism Applied to Pavement Detection by Zhang Jiazhen, Wang Xiulai, Zhao Shuxu

    Published 2025-01-01
    “…Using the SVM classifier with the global sequence alignment algorithm as the main kernel function, the data classification module detects anomalies, so that the algorithm can mine valuable feature attributes from multiple angles as much as possible while stably exerting its classification function. …”
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  11. 1031

    Effect of fibre spinning conditions on the electrical properties of cellulose and carbon nanotube composite fibres spun using ionic liquid as a benign solvent by C. Zhu, S. S. Rahatekar, J. Chen, K. K. Koziol, J. W. Gilman, P. C. Trulove

    Published 2014-03-01
    “…To achieve good dispersion of MWNTs in the cellulose solution dope, MWNTs were non-covalently functionalized using carboxymethyl cellulose (CMC). This significantly improved the dispersion of MWNTs in the solution dope. …”
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  12. 1032

    Union rate and clinical outcomes of second-try scaphoid reconstructions after failed primary scaphoid osteosynthesis or reconstruction. A retrospective, single-center cohort study... by K. Rachunek-Medved, C. Illg, A. Einzmann, J. T. Thiel, A. Daigeler, F. Medved

    Published 2025-05-01
    “…The decision between secondary reconstruction, which aims to restore anatomical integrity, and salvage procedures, which prioritize predictable outcomes, hinges on balancing union potential, functional results, and patient preferences. A tailored approach remains essential to align treatment goals with individual needs.…”
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  13. 1033

    Electric field variations across DLPFC targeting methods in TMS therapy for Alzheimer’s disease by Nianshuang Wu, Yuxuan Shao, Zhen Wu, Shuxiang Zhu, Penghao Wang, Ziyan Zhu, Cheng Zhang, Changzhe Wu, Xiaolin Huo, Hua Lin, Guanghao Zhang

    Published 2025-01-01
    “…Optimal coil orientation exhibited directional specificity: parallel alignment with the LOI E-field produced higher field intensity in the functional target compared to the anatomical target (AD patients: P < 0.001; HCs: P = 0.052), while perpendicular orientation maintained functional stability with reduced anatomical interference (both groups: P < 0.001). …”
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  14. 1034

    Crystal Structural Analysis of <i>Oryza sativa</i> SGT1-TPR Domain by Yongqi Chang, Lifeng Ji, Yiling Qin, Yaqi Yi, Chen Qian, Jie Jiang, Tian Liu, Junfeng Liu, Xin Zhang

    Published 2025-06-01
    “…SGT1 (the suppressor of the G2 allele of Skp1) functions as an adaptor protein that positively regulates plant defense and developmental processes. …”
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  15. 1035

    Two-way transcriptome approach for the identification of common gene targets across four insect orders and its validation in Oxycarenus laetus by Julie Rebecca Joseph Mathari, Habeeb Shaik Mohideen

    Published 2025-07-01
    “…A total of 104 publicly available RNA-Seq datasets, representing 17 pest species were de novo assembled in two ways, first was classified by read length (PE100 and PE150) and secondly as species-specific transcriptomes, and their qualities were assessed (alignment ≥ 90%, BUSCO ≥ 80%). Functional annotation utilizing insect-specific databases and orthology-based filtering identified three highly conserved genes, namely Arginine kinase (ArgK), Ryanodine receptor (RyR), and Serine/Threonine Protein phosphatase (STPP). …”
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  16. 1036

    Virtual surgical planning and custom titanium prosthesis for complex secondary mandibular reconstruction following gunshot injury: A case report by Amir Jalal Abbasi, Somayeh Niakan, Seyed Mohammad Reza Noori, Rashin Bahrami, Nariman Nikparto

    Published 2024-12-01
    “…Advancements in reconstructive surgical techniques in the head and neck area have significantly improved the aesthetic and functional reconstruction of patients. Microsurgical techniques, virtual surgical planning (VSP), CAD-CAM technology, intraoperative dynamic navigation, and advanced implantology have greatly enhanced mandible reconstruction. …”
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  17. 1037

    Enzyme sequence optimisation via Gromov-Wasserstein Autoencoders integrating MSA techniques by Xuze Wang, Yangyang Li, Xiancong Hou, Hao Liu

    Published 2025-12-01
    “…The GWAE model improves representation learning by using the GW distance, thereby generating functional variants with desired characteristics. We also introduce an innovative enzyme dataset construction method that incorporates multiple sequence alignment (MSA) techniques to address sequence length discrepancies, enhancing the accuracy of the optimisation process. …”
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  18. 1038

    Watch out your pins! Periprosthetic femoral fracture at tracking pin site early after robotic-assisted knee arthroplasty treated with dual nail-plate fixation by Jaime Sánchez del Saz, Jaime Coderch Carretero, Javier García Coiradas, Rodrigo García Crespo

    Published 2025-05-01
    “…Surgical management involved combined nail-plate fixation, which promoted both early weight-bearing and functional recovery. At one year postoperatively, the patient achieved satisfactory fracture healing and functional outcomes, with a Knee Society Score of 92 and an EuroQol-5D index value of 0.78.Combined nail-plate osteosynthesis, though more invasive compared to other fixation methods, could be an effective strategy for managing distal femoral fractures following robotic-assisted arthroplasty, especially in obese and elderly patients, due to its biomechanical advantages, supporting early mobilization and weight-bearing with reliable fracture healing.…”
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    Article
  19. 1039

    Exploring the Inhibitory Efficacy of Resokaempferol and Tectochrysin on PI3Kα Protein by Combining DFT and Molecular Docking against Wild-Type and H1047R Mutant Forms by Cristina Paraschiv, Steluța Gosav, Catalina Mercedes Burlacu, Mirela Praisler

    Published 2024-09-01
    “…Our findings, corroborated by DFT calculations performed based on the B3LYP (Becke, three-parameter, Lee-Yang-Parr) hybrid functional and the 6-311G++(d,p) basis set, align well with experimental benchmarks and indicate substantial inhibitory efficacy. …”
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  20. 1040

    Proper Nouns in Context of Arabic as a Foreign Language Learning by Yu. S. Chernykh, O. V. Makarova

    Published 2025-02-01
    “…The use of toponyms constitutes 18%, aligning with the necessary linguistic and cultural aspects of foreign language education. …”
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