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2741
Lecithin:cholesterol acyltransferase binds a discontinuous binding site on adjacent apolipoprotein A-I belts in HDL
Published 2025-05-01“…Lecithin:cholesterol acyltransferase (LCAT) is a high-density lipoprotein (HDL) modifying protein that profoundly affects the composition and function of HDL subspecies. The cholesterol esterification activity of LCAT is dramatically increased by apolipoprotein A-I (APOA1) on HDL, but the mechanism remains unclear. …”
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2742
A New Regional Background Atmospheric Station in the Yangtze River Delta Region for Carbon Monoxide: Assessment of Spatiotemporal Characteristics and Regional Significance
Published 2025-01-01“…The back trajectory analysis and the Weighted Potential Sources Contribution Function (WPSCF) maps highlighted emissions from Anhui, Jiangxi, Zhejiang, and Jiangsu provinces as significant sources. …”
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2743
Constitutive model of metal rubber material considering plastic accumulation behavior
Published 2025-01-01“…Metal rubber, as a novel functional material characterized by its unique three-dimensional reticulated porous structure, has demonstrated significant application value in aerospace engine mounts, aircraft landing gear buffer systems, satellite vibration damping devices, and precision vibration isolation systems for intelligent equipment, owing to its exceptional energy dissipation capacity, remarkable temperature resistance, and excellent environmental adaptability. …”
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2744
ABBA+BraiAn, an integrated suite for whole-brain mapping, reveals brain-wide differences in immediate-early genes induction upon learning
Published 2025-07-01“…Summary: Unbiased characterization of whole-brain cytoarchitecture is crucial for understanding brain function, requiring precise mapping of 2D histological sections onto 3D brain atlases. …”
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2745
Comparative analysis of the gut microbiota composition among three captive hornbills
Published 2025-08-01“…Fecal samples were aseptically collected from 30 hornbills, and 16S rRNA high-throughput sequencing was employed to analyze the composition, diversity, and potential functions of the gut microbiota. The influence of host taxonomic status, sex, and captive environment on the gut microbiota was explored. …”
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2746
Transcriptional and microbial profile of gastric cancer patients infected with Epstein-Barr virus
Published 2025-03-01“…Gene sensitivity and specificity were assessed using ROC curves (p < 0.05, AUC > 0.8). Non-aligned reads were used for microbiome analysis with Kraken2 for bacterial identification. …”
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2747
Towards climate-resilient conservation: Integrating genetics and environmental factors in determining adaptive units of a xeric shrub
Published 2025-01-01“…Peripheral populations exhibited higher genetic loads of loss-of-function alleles, indicating rapid adaptation. The study emphasizes the necessity of incorporating adaptive diversity in conservation strategies and recommends establishing MUs that align with adaptive genotypes and climatic conditions. …”
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2748
Fat storage-inducing transmembrane (FIT or FITM) proteins are related to lipid phosphatase/phosphotransferase enzymes
Published 2017-12-01“…At the molecular level, the sole relevant interaction is that FITMs directly bind to triacyglycerol and diacylglycerol, but how they function at the molecular level is not known. Saccharomyces cerevisiae has two FITM homologues: Scs3p and Yft2p. …”
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2749
Smartphone app to support goal setting in pediatric rehabilitation: app development, usability and acceptability study
Published 2025-08-01“…In phase 2, 7 rehabilitation professionals evaluated the usability of each function, and we made improvements according to their feedback. …”
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2750
Brain metabolic response to repetitive transcranial magnetic stimulation to lesion network in cervical dystonia
Published 2024-11-01“…Conclusions: Our results provide further evidence of abnormal sensory system function in CD and show that a single session of S1 cTBS is sufficient to induce measurable changes in brain glucose metabolism. …”
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2751
MIF-YOLO: An Enhanced YOLO with Multi-Source Image Fusion for Autonomous Dead Chicken Detection
Published 2025-12-01“…Additionally, an exponential moving average (EMA) attention mechanism is strategically embedded within the YOLO algorithm architecture's neck region to bolster the model's ability to discern targets under low-light scenarios, enhancing both its accuracy rates and adaptability. The loss function of the model is refined through the implementation of Modified Partial Distance-IoU (MPDIoU), facilitating a more nuanced evaluation of the overlap of objects. …”
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2752
Revealing the χeff–q Correlation among Coalescing Binary Black Holes and Tentative Evidence for AGN-driven Hierarchical Mergers
Published 2025-01-01“…The first subpopulation has a narrow χ _eff distribution peaking at ∼0.05, whose primary mass function shows a rapid decline beyond ∼40 M _⊙ , in agreement with first-generation BBHs. …”
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2753
The Role of Potassium and KUP/KT/HAK Transporters in Regulating Strawberry (<i>Fragaria</i> × <i>ananassa</i> Duch.) Fruit Development
Published 2025-07-01“…This pattern suggests their functional relevance in early fruit development and turgor maintenance. …”
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2754
First-Principles Study on the CO<sub>2</sub> Reduction Reaction (CO<sub>2</sub>RR) Performance of h-BN-Based Single-Atom Catalysts Modified with Transition Metals
Published 2025-04-01“…In this study, we systematically explore, using density functional theory (DFT), the performance of transition metal (TM = Mn, Fe, Co, Ni, Cu, Zn)-doped defect-type hexagonal boron nitride (h-BN) SACs TM@B<sub>−1</sub>N (B vacancy) and TM@BN<sub>−1</sub> (N vacancy) in both CO<sub>2</sub>RR and the hydrogen evolution reaction (HER). …”
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2755
Electrically tunable liquid-crystal metasurfaces with patterned birefringence and dichroism
Published 2025-05-01“…In the case of devices that are patterned to form polarization gratings, we also characterize the diffraction efficiency as a function of the dichroism and birefringence parameters, which can be tuned jointly by applying an electric field across the cell. …”
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2756
Synthesis and physical characterization of carbon quantum dots from watermelon seed towards a biological application
Published 2025-08-01“…FTIR spectroscopy indicated the presence of functional groups, including hydroxyl, amine, sp2 and sp3 hybridized CH bonds, carbonyl, alkene/alkyne, amide, ether, and CO bonds. …”
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2757
Evaluating the use of eggshell powder and sawdust ash as cement replacements in sustainable concrete development
Published 2025-03-01“…One cubic meter of concrete was chosenas the functional unit. The analysis revealed significant reductions in the endpoint impact categories,including a 59% reduction in ecosystem impacts, 60% in human health, 61% in resource depletion,59.79% in ozone depletion, and 54.32% in fossil fuel depletion. …”
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2758
Nursing practice in relation to older people’s fundamentals of care in nursing homes: An exploratory design
Published 2025-06-01“…We have highlighted the intricate nature of nursing practice, its relationship with clinical decision-making processes, and the functional and performance levels of nursing activities. …”
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2759
Longitudinal evaluation of common and unique brain-networks in variants of primary progressive aphasia
Published 2025-08-01“…Result We found the existence of a left lateralised functional network identical in both PPA groups. This CN, comprising regions associated with language and cognition, remained stable over time (12 months period) and was associated with the severity of dementia. …”
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2760
Linking dietary fiber to human malady through cumulative profiling of microbiota disturbance
Published 2025-02-01“…By leveraging microbiota disturbance similarities, we (1) classified 32 types of dietary fibers into six functional subgroups, revealing correlations with fiber solubility; (2) established associations among 161 diseases, uncovering shared microbiota disturbance patterns that explain disease co‐occurrence (e.g., type II diabetes and kidney diseases) and distinct microbiota patterns that discern symptomatically similar diseases (e.g., inflammatory bowel disease and irritable bowel syndrome); (3) designed a body‐site‐specific microbiota disturbance scoring scheme, computing a disturbance score (DS) for each disease and highlighting the pronounced capacity of Crohn's disease to disturb gut microbiota (DS = 14.01) in contrast with food allergy's minimal capacity (DS = 0.74); (4) identified 1659 fiber‐disease associations, predicting the potential of dietary fiber to modulate specific microbiota changes associated with diseases of interest; (5) established murine models of inflammatory bowel disease to validate the preventive and therapeutic effects of arabinoxylan that notably perturbed the Bacteroidetes and Firmicutes phyla, as well as the Bacteroidetes and Lactobacillus genera, aligning with our model predictions. …”
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