Huanglian Jiedu Decoction Treats Ischemic Stroke by Regulating Pyroptosis: Insights from Multi-Omics and Drug–Target Relationship Analysis by Yixiao Gu, Zijin Sun, Tao Li, Xia Ding

“…Studies suggest inflammation aligns with the traditional Chinese medicine (TCM) concept of “fire-heat syndrome”. …”
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Analysis of Turkish Translations of Snow White by the Brothers Grimm In the Context of the Skopos Theory by Uğur Cansız, Lokman Tanrıkulu

“…The aim of the Skopos theory is to align the translation process with the specific purpose and target audience of the translation, so that the function of the translation is effectively fulfilled in the new context. …”
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EMPIRICAL ASPECTS OF THE INFLUENCE OF THE COOPERATION OF FISCAL INSTITUTIONS ON PROPERTY TAX ADMINISTRATION by Oksana Desyatnyuk, Andriy Krysovatyy, Bohdana Shuliuk, Fedir Tkachyk, Vadym Maslii

“…This approach made it possible to identify the limited fiscal impact of the real estate tax (excluding land), which does not align with global practices and indicates the incomplete fiscal and regulatory function of this tax in Ukraine. …”
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Weakly supervised learning through box annotations for pig instance segmentation by Heng Zhou, Jiuqing Dong, Shujie Han, Seyeon Chung, Hassan Ali, Sangcheol Kim

“…Specifically, we enhance the loss function of an existing weakly supervised instance segmentation model to better align with the requirements of pig instance segmentation. …”
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Ecohydrology and paleoenvironment of the Cretaceous (Albian) Cloverly Formation: insights from multi-taxon oxygen isotope analysis of vertebrate phosphates by M. L. Allen, M. B. Suarez, T. L. Adams, C. A. Suarez

“…Using a multi-taxon framework, we estimated warm-season water temperatures from δ18Osurface_water and δ18Οphosphate of lepisosteid (gar) scales, then converted these to air temperatures using a modern climate transfer function. δ18Οphosphate values ranged from 9.5‰ to 23.2‰ (VSMOW) and varied across taxa. …”
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Optimal Planning of Wind-Based DG: A Two-Stage Approach Linking Penetration Factor, Turbine Type Selection, Capacity, and Power Factors to Minimize Line Losses by Sina Saboktakin, Tarek Medalel Masaud, Ehab F. El-Saadany

“…This is achieved through a novel correlation between DG size, loss reduction, and power factor improvement, ensuring a cost-effective and efficient solution using a single-objective function instead of more complex multi-objective approaches. …”
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Understanding the Impacts of Rainfall Variability on Natural Forage–Livestock Dynamics in Arid and Semi-Arid Environments by Thabo S. Nketsang, Semu Mitiku Kassa, Moatlhodi Kgosimore, Gizaw Mengistu Tsidu

“…Arid and semi-arid environments are characterized by highly variable and unpredictable rainfall patterns, which significantly affect the structure and function of natural ecosystems. Understanding the interconnected relationship between climate variability, forage availability, and livestock dynamics in these regions is crucial to ensure sustainable management. …”
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Dementia patient and caregiver relevant outcomes currently being reported by adult day service centers in the United States by Tina Sadarangani, Keith Anderson, Megan Rose Westmore, Jie Zhong

“…Among these, 80% assess cognitive function. All 10 states capture PLWD's ability to complete activities of daily living. …”
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The Relationship Between Soil and Gut Microbiota Influences the Adaptive Strategies of Goitered Gazelles in the Qaidam Basin by Yiran Wang, Bin Li, Bo Xu, Wen Qin

“…Interactions with soil microbiota can shape the composition and function of the gut microbiota, thereby influencing the hosts’ adaptive strategies. …”
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Investigation of ensembles of deep learning models for improved chronic kidney diseases detection in CT scan images by I.I. Ayogu, C.F. Daniel, B.A. Ayogu, J.N. Odii, C.L. Okpalla, E.C. Nwokorie

“…The loss of renal function is a growing public health issue that affects up to 10 % of the global population. …”
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Unique N-glycosylation signatures in human iPSC derived microglia activated by Aβ oligomer and lipopolysaccharide by Xinyu Tang, Ryan Lee Schindler, Jacopo Di Lucente, Armin Oloumi, Jennyfer Tena, Danielle Harvey, Carlito B. Lebrilla, Angela M. Zivkovic, Lee-Way Jin, Izumi Maezawa

“…AβO- and LPS- specific glycosylation changes could contribute to impaired microglia function, highlighting glycosylation pathways as potential therapeutic targets for AD.…”
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Are your kidneys ok? Detect early to protect kidney health by Joseph A. Vassalotti, Anna Francis, Augusto Cesar Soares Dos Santos Jr, Ricardo Correa-Rotter, Dina Abdellatif, Li-Li Hsiao, Stefanos Roumeliotis, Agnes Haris, Latha A. Kumaraswami, Siu-Fai Lui, Alessandro Balducci, Vassilios Liakopoulos

“…using serum creatinine to estimate kidney function and urine albumin to assess for kidney and endothelial damage. …”
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Research on Optimized Algorithm for Deep Learning Based Recognition of Sediment Particles in Turbulent Flow by WANG Hao, YANG Feiqi, ZHANG Lei, WU Wei, XIE Haonan, ZHAO Lin

“…The YOLOv5 deep learning network structure is enhanced by improving convolutional blocks, incorporating attention mechanisms, and optimizing loss function processing, boosting the detector's overall performance in accurately capturing the motion of particles over short distances. …”
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Integral approach to organelle profiling in human iPSC-derived cardiomyocytes enhances in vitro cardiac safety classification of known cardiotoxic compounds by Brigitta R. Szabo, Brigitta R. Szabo, Jeroen Stein, Anna Savchenko, Thomas Hutschalik, Thomas Hutschalik, Filip Van Nieuwerburgh, Tim Meese, Georgios Kosmidis, Paul G. A. Volders, Elena Matsa, Elena Matsa, Elena Matsa, Elena Matsa

“…Current preclinical hiPSC-CMs models focus on functional changes such as electrophysiological abnormalities, however other parameters, such as structural toxicity, remain less understood.MethodsThis study utilized hiPSC-CMs from three independent donors, cultured in serum-free conditions, and treated with a library of 17 small molecules with stratified cardiac side effects. …”
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High Expression of Myosin ⅩⅥ Predicts Poor Prognosis in Head and Neck Squamous Cell Carcinoma by Keerti Pranith Suryadevara, Balachander Kannan, Chandra Pandi, Anitha Pandi, Abilasha Ramasubramanian, Vijayashree Jayaseelan, Paramasivam Arumugam

“…Further experimental studies are necessary to elucidate MYO16 functional implications and clinical relevance in HNSCC.…”
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High-content Image-based Drug Testing of Patients’ Primary Fibroblasts Reveals Potential New Treatment Options for Localized Scleroderma by Katariina Mähönen, Isabel Mogollon, Antti Hassinen, Minttu Polso, Katja Välimäki, Swapnil Potdar, Al-Amin Chowdhury, Annamari Ranki, Jani Saarela, Vilja Pietiäinen, Jaana Panelius

“…Localized scleroderma is a rare autoimmune disease characterized by progressive fibrosis of the skin and its underlying structures, causing loss of normal tissue structure and function. Myofibroblasts, differentiated from fibroblasts by high expression of α-smooth muscle actin, play a key role in the pathogenesis with continuous production of collagen and other extracellular matrix components. …”
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Characterization and Application of Different Types of Pineapple Leaf Fibers (PALF) in Cement-Based Composites by Julianna M. da Silva, Adilson Brito de Arruda Filho, Lidianne do N. Farias, Everton Hilo de Souza, Fernanda V. D. Souza, Cláudia F. Ferreira, Paulo R. L. Lima

“…An anatomical analysis of the leaves was conducted to identify fiber distribution and structural function. Cement-based composites reinforced with 1.5% (by volume) of long and aligned pineapple leaf fibers were produced and tested in bending. …”
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Acute Effects of Different Alcohol Doses on Psychomotor Performance and Subjective Responses among Healthy Young Women in China by Xiaoqin Yi, Li Xiao, Jin Xiang, Weihao Fan, Yingqiang Fu, Linchuan Liao, Yi Ye

“…Conclusion: The findings of this study align with previous trends, indicating that higher alcohol doses exacerbate impairments in psychomotor functions, leading to heightened risks of traffic accidents or other incidents.…”
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Programmatic Assessment: New Approach of Student Assessment in Medical Education of the Current Century by Hamid Mahdavifard

“…However, traditional approaches to assessment, which generally focus exclusively on the summative function of assessment, are not appropriate in CBE. …”
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Widely targeted metabolome combined with morphophysiological analyses of different year-old xylems revealed flavonoids associated with heartwood in Toona sinensis by Lijiao Fan, Shuxin Chen, Changqing Qu, Yanru Fan, Minyan Wang, Jingxia Yang, Yuntao Ji, Jun Liu, Xiaojiao Han

“…Heartwood, on the other hand, contains a notable quantity of flavonoid functional groups. In 6YH, the levels of catechin, epicatechin, and cyanidin were higher, whereas in 6-year-old sapwood (6YS), their concentrations were lower. …”
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