Predictive Factors of Lapatinib and Capecitabine Activity in Patients with HER2-Positive, Trastuzumab-Resistant Metastatic Breast Cancer: Results from the Italian Retrospective Mul... by Stefania Gori, Alessandro Inno, Valentina Rossi, Monica Turazza, Elena Fiorio, Alessandra Fabi, Giancarlo Bisagni, Jennifer Foglietta, Daniele Santini, Ida Pavese, Arianna Pellegrino, Alberto Zambelli, Patrizia Vici, Vita Leonardi, Sandro Barni, Silvana Saracchini, Giuseppe Bogina, Fabiana Marchetti, Simona Duranti, Gianluigi Lunardi, Filippo Montemurro

“…Patents with a PFS longer than 7 months had a significantly longer OS, compared with patients with a PFS equal to or shorter than 7 months (36 vs 15 months; p<0.001). …”
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Patient Satisfaction with Clear Aligners vs. Traditional Braces: A Comparative Study by AbdulMajeed AlMogbel

“…However, both treatments were equally effective in achieving orthodontic goals, indicating that the choice of modality should consider individual preferences and case complexity.…”
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Study on the diagnostic value of folic acid-targeted nano-microbubbles in breast microcarcinoma by Nianyu Xue, Zhenyu Shen, Zhenbin Xu, Shengmin Zhang

“…It is difficult to detect breast microcarcinomas less than or equal to 5 mm by imaging examination.MethodsFolic acid-targeted nanobubbles (FA-TNBs) were prepared by the thin-film hydration method. …”
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Effect of Anti-Emetic Combination of Sevoflurane / Propofol Anesthesia Technique in Laparoscopic Cholecystectomy by Muhammad Salman Maqbool, Muhammad Alam, Muhammad Umer Draz, Ayesha Shahid, Shumaila Ashfaq

“…Methodology: Patients were recruited in interventional groups by lottery method as n=160, with 80 cases allocated in each group. …”
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Examination of cardiovascular function variables in tooth extraction under local anesthesia by Životić-Vanović Mirjana, Marjanović Marjan

“…However, there is a question if it is equally safe to apply a local anesthetic combined with a vasoconstrictor (adrenaline) in healthy persons, and in the patients with a certain cardiovascular system disease. …”
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The impact of age on genetic risk for common diseases. by Xilin Jiang, Chris Holmes, Gil McVean

“…Previous work has shown that genetic factors are not equally relevant to human traits across age and other contexts, though the reasons for such variation are not clear. …”
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Effects of combined training performed two or four times per week on 24-h blood pressure, glycosylated hemoglobin and other health-related outcomes in aging individuals with hypert... by Rodrigo Ferrari, Lucas Betti Domingues, Leandro de Oliveira Carpes, Paula de Azevedo Frank, Vinícius Mallmann Schneider, Sandra C Fuchs, GET Study Group

“…<h4>Purpose</h4>To compare the effects of a combined training program (resistance plus aerobic exercise) performed four or two times per week on 24-h ambulatory blood pressure and other health-related outcomes in middle-aged and older individuals with hypertension.<h4>Methods</h4>This study will be a randomized, parallel group, two-arm, superiority trial. …”
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Optimization of the Number of Active Subcarriers and M-PAM Modulation Constellation Pattern for OFDM-IM Systems by Farshad Jalili kharajoo, SeyyedHadi SeyyedMasoumian Charandabi

“…The proposed optimal method, particularly designed for 4-symbol Pulse Amplitude Modulation and 8-group OFDM-IM, has resulted in a 6.25% increase in the number of transmitted bits compared to previous methods. …”
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Quality of recovery (QoR-15) following opioid-free versus opioid anaesthesia for elective endoscopic nasal surgeries: A randomised, open-label comparative trial by Yashika Pandey, Manisha Sapate, Harsha H. Narkhede, Poonam Mane

“…Methods: A randomised, open-label trial was conducted to evaluate the quality of recovery (QoR). …”
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The Relationship of Neck pain and Smart Phones Usage among students: A Cross-Sectional Study in Erbil City by ShwanQadir Media, Alaa Usama Ahmed

“…Overusing phones for more than 4hours per day was 78%, and only 22% underused the smartphone (less than and equal to four hours). Conclusion: Prevalence of neck pain related to phone use among medical faculty students in Erbil city was high. …”
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Metabolic syndrome treatment: focusing on acarbose by I. E. Chazova, B. B. Mychka

“…All participants were randomized into three equal groups: two groups receiving acarbose (150 or 300 mg/d) and a control group. …”
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Prevalence of Cardiovascular Risk Factors in the Population of the Area I in the Municipality of Cienfuegos by Hilda María Delgado Acosta, Karelis Lastre Navarro, María Lina Valdés Gómez, Mikhail Benet Rodríguez, Alain Morejón Giraldoni

“…<strong><br />Objective:</strong> to identify the prevalence of cardiovascular risk factors in the population of the Area I in the municipality of Cienfuegos during 2010-2011. <strong><br />Methods:</strong> a descriptive cross-sectional study was conducted to determine the prevalence of cardiovascular risk factors in the population of the Area I in Cienfuegos by means of a complex three-stage equal probability sample of 581 people. …”
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Push-Out Bond Strength of Experimental Apatite Calcium Phosphate Based Coated Gutta-Percha by Afaf Y. Al-Haddad, Muralithran G. Kutty, Zeti Adura Che Ab Aziz

“…To evaluate the push-out bond strength of experimental apatite calcium phosphate coated gutta-percha (HAGP) compared to different commercially available coated gutta-percha root obturation points. Methods. Extracted teeth were selected and instrumented using ProTaper rotary files. …”
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Sample sizes for non-inferiority studies based on the difference between two proportions: a unified approach for difference, ratio and odds ratio models by Bruno Mario Cesana, Paolo Antonelli

“…Background: It is never easy to make sample size calculation for two-arm, non-inferiority studies with a primary proportion outcome not only because the different parameterisations involved in the difference, ratio, and odds ratio models lead to different non-inferiority margins and different sample size results, but also because of the different efficiency of the respective sample size formulae. Methods: According to a formal statistical approach, we showed how to express the non-inferiority margins of the three models by keeping the probability (success or failure) of the standard treatment fixed (considered as “known” in the planning phase of a trail), and equal under the null and alternative hypotheses as the statistical basis for sample size calculation. …”
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Disputing Authorship: Reinscriptions of Collective Modes of Knowledge Production by Andréa Gill, Marta Fernández

“…This entry point into the conversation on who has the power to know and control the meanings of intersectional inequalities enables a focus on practice, pedagogy, and methods to unpack the ethical and epistemological questions at hand. …”
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Cost-effectiveness of pirfenidone compared to all available strategies for the treatment of idiopathic pulmonary fibrosis in France by Emilie Clay, Olivier Cristeau, Romain Chafaie, Alexandrina Pinta, Benjamin Mazaleyrat, Vincent Cottin

“…The total number of QALYs accumulated equalled 5.20 (6.91 LYs), 4.52 (5.98 LYs), and 3.79 (4.98 LYs), respectively. …”
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Pengaruh Media Pop Up Book Terhadap Hasil Belajar Ilmu Pengetahuan Alam dan Sosial (IPAS) Siswa Kelas V SD Negeri 88 Singkawang by Hengki, Mertika, Dewi Mariana

“…A type of quantitative research with experimental methods. Research Design Nonequivalent Control Group Design. …”
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Simulation of the Extruder Screw Parameters by M. G. Zagoruiko, V. V. Vasilchikov, A. K. Mamakhai

“…The experiment planning method was applied. They examined the process of press extruder operation with a variable pitch screw during the lentils processing. …”
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Elucidating the Differential Mechanisms of Jingui Shenqi Pill and Mingmu Dihuang Pill in the Treatment of Diabetic Nephropathy Based on Yin-Yang Theory by Bi S, Xu Z, Yuan A, Wang Z, Liu Y, Yu B, Tian J, Liu C, Qiao L, Wang Z, Zhang Y

“…., Ltd, Beijing, 100000, People’s Republic of China&ast;These authors contributed equally to this workCorrespondence: Yanling Zhang, Email zhangyanling@bucm.edu.cn Zhibin Wang, Email wangzhibin4804@126.comBackground: The Yin-Yang attributes of MMDH and JGSQ in treating diabetic nephropathy (DN) remain unexplored.Methods: UPLC-MS identified formula components, network pharmacology analyzed common DN targets, and in vitro renal fibrosis models assessed efficacy. …”
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Decentralizing Democracy: Secure and Transparent E-Voting Systems with Blockchain Technology in the Context of Palestine by Eman Daraghmi, Ahmed Hamoudi, Mamoun Abu Helou

“…Elections and voting play a crucial role in the development of a democratic society, enabling the public to express their views and participate in the decision-making process. Voting methods have evolved from paper ballot systems to e-voting systems to preserve the integrity of votes, ensuring a secure, transparent, and verifiable process. …”
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