The feasibility and efficacy of the Position Acute Tone External system score in evaluating hemorrhoid severity and guiding clinical treatment by Sun Songpeng, Wan Weiping, Li Tianyu, Wu Yao, Wang Jianguo, Xu Fangfang, Zhang Zhiyun, Tian Ying, Lin Mei, Cao Qiaorong, Wang Zhanjun, Li Xinjian, Yang Tianqing, Liao Riyu, Xieyida Kuerban, Ni Hong, Huo Xingxiao, Jia Shan, Long Junhong, Zhang Shuxin

“…[Objectives] To analyze the feasibility and efficacy of the Position Acute Tone External (PATE) system score in evaluating hemorrhoid severity and guiding clinical treatment. [Methods] This cross-sectional study conducted a questionnaire survey among patients with hemorrhoids in outpatient/ward settings at six anorectal centers from November 2021 to November 2022. …”
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Biochemical–molecular–genetic biomarkers in the tear film, aqueous humor, and blood of primary open-angle glaucoma patients by Maria D. Pinazo-Durán, Maria D. Pinazo-Durán, Maria D. Pinazo-Durán, Vicente Zanón-Moreno, Vicente Zanón-Moreno, Carolina García–Villanueva, Alessio Martucci, Cristina Peris-Martínez, Cristina Peris-Martínez, Jorge Vila-Arteaga, Jose J. García-Medina, Jose J. García-Medina, Jose J. García-Medina, Jose J. García-Medina, Irene Andrés–Blasco, Irene Andrés–Blasco, Irene Andrés–Blasco, Alex Gallego–Martínez, Alex Gallego–Martínez, Carlo Nucci, Julian García–Feijoo

“…As a response to high intraocular pressure, the clinical and molecular glaucoma biomarkers indicate the biological state of the visual system. Classical and uncovering novel biomarkers of glaucoma development and progression, follow-up, and monitoring the response to treatment are key objectives to improve vision outcomes. …”
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Application of platelet-rich plasma therapy combined with 5E rehabilitation nursing mode for patients with knee osteoarthritis (富血小板血浆联合5E康复护理模式在膝骨性关节炎患者中的应用)... by AN Linjing (安林静), ZHAO Chen (赵晨), CHANG Yueyuan (常月圆), PAN Yaying (潘亚英), CHEN Yanqi (程艳琪), ZHANG Bing (张兵), CHEN Weinan (陈炜楠), GAO Bei (高蓓), NIU Jing (牛静), ZHANG Ting (张婷)

“…Objective To explore the clinical effect of platelet-rich plasma therapy (PRP) combined with 5E rehabilitation nursing mode for patients with knee osteoarthritis. Methods Totally 80 patients with knee osteoarthritis admitted to the orthopedics department of the hospital from March 2021 to March 2023 were selected as subjects. …”
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Evaluation of the effectiveness of Tofacitinib in rheumatoid arthritis in real clinical practice: The relationship between pain relief in the first 4 weeks and disease activity aft... by A. E. Karateev, E. Yu. Pogozheva, V. N. Amirjanova, E. S. Filatova, A. M. Lila, V. I. Mazurov, R. R. Samigullina, A. M. Dadalova, A. Yu. Dyo, D. S. Chakieva, A. A. Baranov, N. A. Lapkina, E. N. Koltsova, N. A. Kiryukhina, I. N. Shchendrigin, T. G. Rasevich, A. F. Davydova, I. V. Semizarova, I. A. Shafieva, I. B. Bashkova, D. A. Bobrikova, D. A. Murtazalieva, I. N. Kushnir, E. V. Kalinina, T. S. Salnikova, I. M. Marusenko, O. V. Semagina, I. B. Vinogradova, D. G. Krechikova, M. Yu. Semchenkova, E. L. Nasonov

“…The mean severity of pain at baseline was 5.3±2.0 on the visual analogue scale (VAS); 51.1% of patients had signs of CS (CSI>40), 15.9% had NCP (PainDETECT>18). 7 days after the start of therapy, there was a significant decrease in pain – to 4.1±1.8 according to VAS (p<0.05) and CS – 40.4±13.5 to 36.5±12.5 according to CSI (p=0.01). …”
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Artificial intelligence contouring in radiotherapy for organs-at-risk and lymph node areas by Céline Meyer, Sandrine Huger, Marie Bruand, Thomas Leroy, Jérémy Palisson, Paul Rétif, Thomas Sarrade, Anais Barateau, Sophie Renard, Maria Jolnerovski, Nicolas Demogeot, Johann Marcel, Nicolas Martz, Anaïs Stefani, Selima Sellami, Juliette Jacques, Emma Agnoux, William Gehin, Ida Trampetti, Agathe Margulies, Constance Golfier, Yassir Khattabi, Olivier Cravéreau, Alizée Renan, Jean-François Py, Jean-Christophe Faivre

“…We have chosen to define the threshold of an average score equal to or greater than 2 to characterize a high-performing AI software, meaning an AI with minimal to moderate corrections but usable in clinical routine. …”
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Combining transcranial direct current stimulation with music therapy improves cognitive function in schizophrenia: study protocol for a randomized, double-blind, sham-controlled cl... by Yange Wei, Yange Wei, Shanyuan He, Peng Luo, Hanshuo Su, Yuanle Chen, Shisen Qin, Zhongguo Zhang, Rongxun Liu, Dongshuai Wei, Juan Wang, Fei Wang, Fei Wang, Chuansheng Wang

“…The anodal electrode of tDCS will be positioned over the medial prefrontal cortex (mPFC), while the cathodal electrode will be placed over the visual cortex. MT will incorporate both Western Mozart and traditional Chinese classical music. …”
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Clinical outcomes of limited open reduction and intramedullary nailing with steel cable cerclage in Seinsheimer III femoral subtrochanteric fractures by Hongru Cai, Hongru Cai, Hongru Cai, Hongru Cai, Hongru Cai, XueYi He, XueYi He, XueYi He, XueYi He, XueYi He, Zhengchao Zhang, Zhengchao Zhang, Zhengchao Zhang, Zhengchao Zhang, Zhengchao Zhang, Pinhua Chen, Pinhua Chen, Pinhua Chen, Pinhua Chen, Pinhua Chen, Ruoli Wang, Ruoli Wang, Ruoli Wang, Ruoli Wang, Ruoli Wang, Qi Fang, Qi Fang, Qi Fang, Qi Fang, Qi Fang, Zhixian Xu, Zhixian Xu, Zhixian Xu, Zhixian Xu, Zhixian Xu, Wubing He, Wubing He, Wubing He, Wubing He, Wubing He

“…These findings support the clinical utility of steel cable cerclage as an adjunct fixation method, particularly for cases where closed reduction is challenging. …”
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Cultural influences on fidelity components in recovery colleges: a study across 28 countries and territories by Charlotte Hanlon, Lisa Brophy, Peter Bates, Samson Tse, Claire Henderson, Ioannis Bakolis, Mike Slade, Michio Murakami, Julie Cooper, Vicky Stergiopoulos, Michael Ryan, Susana Ochoa, Daniel Hayes, Amy Ronaldson, Bernd Puschner, Ashleigh Charles, Ramona Hiltensperger, Yasuhiro Kotera, Wouter Vanderplasschen, Julie Repper, Simran Takhi, Simon Felix, Mariam Namasaba, Simon Lawrence, Vanessa Kellermann, Agnieszka Kapka, Danielle Dunnett, Tesnime Jebara, Sara Meddings, Clara De Ruysscher, Lene Eplov, Charlotte Toernes, Dagmar Narusson, Yuki Miyamoto, Stynke Castelein, Trude Gøril Klevan, Hannah Morland-Jones, Edith Moore, Gianfranco Zuaboni, Laura Asher, Jonna Tolonen, Mário Andrade, Daniel Elton, Jason Grant

“…Seven RFM items showed associations with cultural dimensions. Equality was linked to short-term orientation, while learning was associated with individualism and uncertainty avoidance. …”
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Spatial Analysis of Bioclimatic Vulnerability of Kermanshah Facing Heat Wave by Hossein Yavari, Mstafa Karampour, Dariush Yarahmadi

“…The area of this critical category was 3072 hectares, equal to 0.32 of the total area of the Kermanshah. …”
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Treatment effects of human amnion-derived mesenchymal stem cells for skin lesions and metastatic pulmonary calcification in calciphylaxis patients – case series and literature revi... by Shijiu Lu, Ming Zeng, Fan Li, Chun Ouyang, Jingjing Wu, Jiaying Hu, Yanggang Yuan, Hongqing Cui, Yi Xu, Wei Liu, Ling Zhang, Yan Lu, Zhonglan Su, Xiaoxue Ye, Cui Li, Anning Bian, Chunyan Jiang, Yugui Cui, Xiang Ma, Song Ning, Xiaolin Lv, Ling Wang, Jiahui Yang, Xiuqin Wang, Ningxia Liang, Changying Xing, Jiayin Liu, Lianju Qin, Ningning Wang

“…Effects were evaluated using the Visual Analogue Scale (VAS), modified Bates-Jensen Wound Assessment Tool for CUA (BWAT-CUA), wound quality of life questionnaire (Wound-QoL), and histological analysis. …”
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Efficacy, safety and cost-effectiveness of methotrexate, adalimumab or their combination in non-infectious non-anterior uveitis: a protocol for a multicentre, randomised, parallel... by José Antonio Pinto, Alex Fonollosa, Ester Carreño, Maria Isabel Rodriguez, David Diaz-Valle, Diana Peiteado, Luis Rodriguez-Rodriguez, Miguel Cordero-Coma, Marta Tejera Santana, Lidia Cocho, Ana Belen Rivas, Amanda Lopez-Picado, Valentina Calamia, Felix M Francisco Hernandez, Angel Garcia-Aparicio, Javier Garcia-Gonzalez, Jose Juan Mondejar, Leticia Lojo-Oliveira, Llucí Martínez-Costa, Santiago Munoz, Beatriz Rodriguez-Lozano, Esperanza Pato, Elena Molina, Luis Alberto Tebar, Mara Albert Fort, Mayte Ariño Gutierrez, Pedro Arriola Villalobos, Joseba Artaraz Beobide, Antonio Atanes Sandoval, Jose Manuel Sanchez, Francisco Blázquez, Pablo Borges Deniz, Lara Borrego Sanz, Gabriela Bustamante Sanchez-Arnedo, Bruno Casco Silva, Ricardo Cuiña Sardiña, Almudena De Pablo Cabrera, Maria Del Mar Esteban Ortega, Patricia Fernandez Puente, Dalifer Dayanira Nuñez, Javier Garcia Bella, Sara Garcia Carazo, Luis Garcia Onrubia, Jose Maria Morales, Jose Antonio Fernandez, Vanesa Hernandez Hernandez, Inés Hernanz Rodriguez, Jose Maria Cantalapiedra, Ventura Hidalgo Barrero, Maria De Jovani Casano, Sara López Sierra, Virginia Lozano Lopez, Alfredo Madrid Garcia, Rosalia Mendez Fernandez, Pilar Nozal Aranda, Eugenio Perez Blazquez, Chamaida Plasencia Rodriguez, Sheila Recuero Diaz, Ignacio Robles Barrena, Esther Rodriguez Almaraz, Fayna Maria Gonzalez, Guadalupe Rodriguez Martinez, Fredeswinda Isabel Bueno, Ioana Ruiz Arruza, Beatriz Sanchez Marugan, Olga Sanchez Pernaute, Armelle Schlinker Giraud, Alvaro Seijas Lopez, Patricia Simon Alonso, Elia Valls Pascual

“…However, a direct comparison between these two treatment strategies has not been carried out yet.Methods and analysis The Combination THerapy with mEthotrexate and adalImumAb for uveitis (CoTHEIA) study is a phase III, multicentre, prospective, randomised, single-blinded with masked outcome assessment, parallel three arms with 1:1:1 allocation, active-controlled, superiority study design, comparing the efficacy, safety and cost-effectiveness of methotrexate, adalimumab or their combination in non-infectious non-anterior uveitis. …”
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Polymorphous corneal dystrophy subtype 3 and keratoconus aggravation after corneal refractive surgery in a three-generation family carrying both ZEB1 and ZNF469 pathogenic variant by Qinghong Lin, Qinghong Lin, Qinghong Lin, Qinghong Lin, Qinghong Lin, Qinghong Lin, Xuejun Wang, Xuejun Wang, Xuejun Wang, Xuejun Wang, Xuejun Wang, Xiaoliao Peng, Xiaoliao Peng, Xiaoliao Peng, Xiaoliao Peng, Xiaoliao Peng, Xiaosong Han, Xiaosong Han, Xiaosong Han, Xiaosong Han, Xiaosong Han, Xiaoyu Zhang, Xiaoyu Zhang, Xiaoyu Zhang, Xiaoyu Zhang, Xiaoyu Zhang, Ling Sun, Ling Sun, Ling Sun, Ling Sun, Ling Sun, Yan Wang, Shengtao Liu, Shengtao Liu, Shengtao Liu, Shengtao Liu, Shengtao Liu, Xingtao Zhou, Xingtao Zhou, Xingtao Zhou, Xingtao Zhou, Xingtao Zhou

“…Both the proband (III1) and her younger brother (III2) underwent SMILE to correct refractive errors. One year later, visual acuity of III1 decreased significantly with KC aggravation and corneal opacification. …”
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Children with disabilities during the COVID-19 pandemic: medical and social comparative study by Leyla S. Namazova-Baranova, Elena A. Vishneva, Elena V. Kaytukova, Natalia V. Ustinova, Anna A. Alekseeva, George A. Karkashadze, Irina A. Belyaeva, Julia G. Levina, Nato D. Vashakmadze, Marina V. Fedoseenko, Grigory V. Revunenkov, Aiaz M. Mamedieiarov, Andrey N. Surkov, Irina V. Zelenkova, Maria I. Slipka, Aleksandr V. Pashkov, Olga B. Gordeeva, Elena A. Gorbunova, Safarbegim H. Sadilloeva, Kseniya S. Katalkina

“…The pandemic and its consequences can have a devastating impact on the health and development of children, especially those in vulnerable situations — children with disabilities.The aim of the study is a medical and social assessment of the effect of the COVID—19 pandemic and its consequences on families with children with disabilities.Methods. A descriptive study using the Google forms platform was conducted using the cross-sectional method. …”
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The impact of aripiprazole on neurocognitive function in individuals at clinical high risk for psychosis: A comparison with olanzapine and non-antipsychotic treatment by JiaHui Zeng, Andrea Raballo, JiaYi Ye, YuQing Gao, WenJun Su, YanYan Wei, XiaoChen Tang, LiHua Xu, YeGang Hu, Dan Zhang, HuiRu Cui, YingYing Tang, XiaoHua Liu, HaiChun Liu, Tao Chen, ChunBo Li, JiJun Wang, TianHong Zhang

“…Among the antipsychotic groups, aripiprazole was associated with better visual learning outcomes than olanzapine. Improvements in neurocognition correlated significantly with clinical symptom relief and overall functional gains at follow-up assessments. …”
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Quantifying the Visuo-Perceptual Segregation Between Ortabayır and Levent District in Istanbul through Semantic Segmentation by Jood Kassab, Can Uzun

“…The study aims to elaborate on the visual and perceptual segregation between Levent and Ortabayir while providing quantitative evidence. …”
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Standardized aqueous extract of Abutilon theophrasti Medic. ameliorates oxidative stress and inflammatory responses against hydrochloric acid/ethanol-induced gastric ulcer in rats by Hui Guo, Hui Guo, Zihan Xu, Zihan Xu, Lili Zhu, Meng Zhu, Meng Zhu, Weijin Zhang, Weijin Zhang, Man Gong, Mengyun Liu, Mengyun Liu, Mengmeng Wang, Mengmeng Wang, Erping Xu, Liping Dai, Liping Dai

“…A protein–protein–substance network construction and Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway enrichment analyses were performed to explore and visualize the biological targets, effective substances, and signaling pathways involved in the anti-GU effects of ATAE. …”
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Efficacy and safety of rapid dose escalation of methotrexate in rheumatoid arthritis. Results of the multicenter “METEOR” study by V. N. Amirjanova, E. Yu. Polishchuk, O. N. Anoshenkova, I. B. Vinogradova, E. V. Zonova, L. V. Ivanova, R. R. Samigullina, T. S. Salnikova, E. L. Shakhramanova, E. I. Shmidt, S. P. Yakupova, A. M. Lila, E. L. Nasonov

“…There was a marked decrease in pain from 65.6±13.07 to 20.5±17.1 mm in VAS (Visual Analogue Score) (p<0.001), which contributed to an improvement in the functional state: the HAQ (Health Assessment Questionnaire) index decreased on average from 1.47±0.65 to 0.64±052 points. …”
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Evaluating the Elements of Vitality in Jahānshahr Walkway, Karaj City, Iran by Mina Heydari Tamrabadi, Habibollah Fasihi, Tajaddin Karami

“…This research aimed to evaluate the vitality components of Jahānshahr Walkway, a major thoroughfare that played a significant social, economic, and cultural role in the bustling and lively part of Karaj City, Iran. Materials & Methods:The study focused on Jahānshahr Walkway located in the northeastern region of Karaj, Iran. …”
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Application of acupuncture therapy in relieving the anxiety among patients undergoing glaucoma surgery (针灸疗法缓解青光眼手术患者焦虑的效果观察) by LI Gonghui (李贡辉), (毛珍), MA Di (马迪), HUANG Chukai (黄楚开), TAN Ronghui (谭容慧)

“…Objective To investigate the effect of acupuncture therapy in relieving the anxiety of patients undergoing glaucoma surgery. Methods Totally 95 glaucoma patients undergoing trabeculectomy were randomly divided into two groups: control group with 47 cases and observation group with 48 cases. …”
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Study of Planting Pattern and Herbicide Effects on Weed Population and Chickpea (Cicer arietinum L.) Grain Yield by Hossein Najafi, Soheyla Pourheydar Ghafarbi, Gholamreza Gahramanian, Ajang Jahedi

“…Optimizing chickpea row-spacing and the application possibility of non-selective herbicides in chickpea was our objective in this experiment. Materials and Methods In order to study planting pattern and chemical control effects on weed population and yield of rain-fed chickpea farming, two experiments conducted. …”
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