Optimization, Design, and Implementation of Biodiversity-Focused Fisheries Survey Stations: A Case Study of the Coastal Waters of Maoming by Yuexiu DENG, Yongheng HUANG, Jianyu DONG, Ning CHEN, Jing ZHANG, Xuefeng WANG

“…However, most research primarily focuses on optimizing either stratification or sample allocation and pays less attention to methods that simultaneously optimize both stratification and sample allocation. …”
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Immune Microenvironment Characterization and Machine Learning-Guided Identification of Diagnostic Biomarkers for Ulcerative Colitis by Zheng Q, Wang L, Zhang Y, Peng J, Hou J, Wang H, Ma Y, Tang P, Li Y, Li H, Chen Y, Li J, Chen Y

“…Current treatments often show limited efficacy, highlighting the need for novel diagnostic and therapeutic approaches.Methods: RNA-Seq data from 495 UC patients and 320 controls (training dataset) and 389 UC patients and 209 controls (testing dataset) were analyzed. …”
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A Sociological Study of Monetary Attitudes among Citizens of Tehran by Nahid Abdoli, Asadollah Babaiefard

“…Money has long served to equalize disparities, evolving into a primarily symbolic entity. …”
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Optimizing Treatment for Hospitalized Patients with COPD: A Study on the Impact of a LINE App-Based Multidisciplinary Team Approach Targeting Pharmacological Treatment, Lifestyle C... by Huang HY, Chen CL, Lin YL, Chen SC, Lee LC, Dai HM, Chiang CY, Chang YF, Lu H, Lee MR, Yang CC, Su CH, Chiang YZ, Yang MC, Shyu RY, Lan CC

“…This study explored the effectiveness of LINE-based MDT interventions in hospitalized patients with COPD.Methods: This retrospective analysis included patients with COPD admitted for exacerbations and compared their outcomes before and after the implementation of LINE-based MDT care. …”
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Analytical investigation of the patrimonial law and inheritance of women in Sassanid era marriages by Parvin Davari, Esmaeil Sangari

“…Therefore, no women/daughters could inherit equally, and the difference in their inheritance shares was substantial. …”
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Adverse childhood experiences and subsequent experiences of intimate partner violence in adulthood: a gender perspective by Zheng Tian, Nan Zhang, Yimiao Li, Yibo Wu, Lan Wang

“…Abstract Aims Investigate the prevalence of adverse childhood experience (ACE) and intimate partner violence (IPV) using a large representative Chinese sample, explore the association mechanism between ACE and adult exposure to IPV and to examine gender differences. Methods A total of 21,154 participants were included in this study. …”
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Analysis of the Rights and Obligations of Stakeholders in China’s National Park Concession System by Le ZHONG, Zhicong ZHAO

“…Following the principle of equality of stakeholders’ rights and obligations, this research aims to provide a comprehensive theoretical and practical framework to guide ongoing research and the systematic construction of China’s national park concession system.MethodsThis research is designed to investigate the overarching and universal challenges associated with the establishment of the national park concession system in China. …”
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Comprehensive Analysis of Differences in N6-Methyladenosine RNA Methylation Groups in CVB3-Induced Viral Myocarditis and Identification of the Anti-Apoptotic Role of RBM15B by Hu Y, Lin J, Yi L, Cheng S, You G, Chang H, Liu H, Yang Z, Chen S

“…In this study, we investigated alterations in global RNA m6A methylation levels during CVB3 infection using both in vitro and in vivo models, and further examined the regulatory role of the m6A methyltransferase RBM15B in vitro.Methods: First, the total quantity of m6A was quantified in Balb/c mice and HL-1 cells with CVB3 infection via m6A dot blot analysis. …”
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Preparation, and ex vivo and in vivo Characterization of Favipiravir-Loaded Aspasomes and Niosomes for Nose-to-Brain Administration by Salamah M, Volk B, Lekli I, Bak I, Gyöngyösi A, Kozma G, Kónya Z, Szalenkó-Tőkés Á, Kiricsi Á, Rovó L, Balogh-Weiser D, Zupkó I, Csóka I, Katona G, Balogh GT

“…., Budapest, Hungary; 4Department of Pharmacology, Faculty of Pharmacy, University of Debrecen, Debrecen, Hungary; 5Faculty of Science and Informatics, Department of Applied & Environmental Chemistry, University of Szeged, Szeged, Hungary; 6Department of Oto-Rhino-Laryngology and Head-Neck Surgery, University of Szeged, Szeged, Hungary; 7Department of Organic Chemistry and Technology, Faculty of Chemical Technology and Biotechnology, Budapest University of Technology and Economics, Budapest, Hungary; 8Department of Physical Chemistry and Materials Science, Faculty of Chemical Technology and Biotechnology, Budapest University of Technology and Economics, Budapest, Hungary; 9Department of Pharmaceutical Chemistry, Semmelweis University, Budapest, Hungary; 10Center for Pharmacology and Drug Research & Development, Department of Pharmaceutical Chemistry, Semmelweis University, Budapest, Hungary*These authors contributed equally to this workCorrespondence: Gábor Katona, Institute of Pharmaceutical Technology and Regulatory Affairs, Faculty of Pharmacy, University of Szeged, Eötvös Str. 6, Szeged, H-6720, Hungary, Email katona.gabor@szte.hu György Tibor Balogh, Department of Pharmaceutical Chemistry, Semmelweis University, Hőgyes Endre Str. 9, Budapest, H-1092, Hungary, Email balogh.gyorgy.tibor@semmelweis.huPurpose: The present study aimed to develop and compare the intranasal applicability of favipiravir-loaded aspasomes (FAV-ASPs) using film hydration method, and favipiravir-loaded niosomes (FAV-NIOs) using ethanol injection method.Methods: The FAV-ASP and FAV-NIO formulations were characterized according to nanoparticulate characteristics (DLS, drug loading, drug encapsulation efficacy, droplet size distribution), drug release and permeability behavior.Results: The optimized FAV-ASP formulation (FAV-ASP8) consisted of FAV, ascorbyl palmitate, Span® 60 and cholesterol (30:25:25:50 w/w) with nano-scale size range (292.06 ± 2.10 nm), narrow polydispersity index (PDI) value (0.36 ± 0.03), adequate zeta potential (− 74.73 ± 3.28 mV) and acceptable encapsulation efficiency (55.33 ± 0.41%). …”
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Overtime Histological Changes in the Lungs after Intoxication with Baclofen Alone or in Combination with Ethanol (Experimental Study) by O. L. Romanova, M. L. Blagonravov, P. G. Dzhuvalyakov, V. I. Torshin, A. V. Ershov, E. Kh. Barinov

“…The aim of the study was to evaluate the overtime histological changes in the lungs after intoxication with baclofen alone or in combination with ethanol.Materials and methods. The experiment was carried out on 35 male Wistar rats weighing 290-350 g and aged 20 weeks. …”
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Reducing Greenhouse Gas Emissions in Dairy Cow Breeding Units through Ration Management with Emphasis on the Life Cycle Assessment Approach by Zahra Rashid Sanchuli, Seyed-Ali Hosseini-Yekani, Fatemeh Kashiri Kolaei

“…The total cost is also equal to 396,480 Rials, which is reduced by 26% compared to the basic state. …”
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ASSESSMENT OF ADHERENCE TO TREATMENT AND FACTORS AFFECTING IT IN PATIENTS WITH STABLE ISCHEMIC HEART DISEASE DURING THERAPY WITH NICORANDIL by S. Yu. Martsevich, Yu. V. Lukina, N. P. Kutishenko, A. V. Akimova, V. P. Voronina, O. V. Lerman, O. V. Gaisenok, T. A. Gomova, A. V. Ezhov, A. D. Kuimov, R. A. Libis, G. V. Matyushin, T. N. Mitroshina, G. I. Nechaeva, I. I. Reznik, V. V. Skibitsky, L. A. Sokolova, A. I. Chesnikova, N. V. Dobrynina, S. S. Yakushin

“…The leading cause of non-adherence at the beginning of therapy is polypharmacy, for the continuation of the recently started treatment – the adverse events; for long-term sustained treatment – equally polypharmacy, drug adverse events and the lack of treatment efficacy.…”
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The Impact of Gut Microbiota on Chronic Obstructive Pulmonary Disease: A Dual-Sample Mendelian Randomization Study by Niu N, Zhao J, Li H, Miao Y, Chen F, Liu J, Cao L, Ji T, Gao F, Xie S, Zhang Y

“…Hence, we conducted a dual-sample Mendelian randomization study to elucidate the impact of gut microbiota on COPD.Methods: We utilized single-nucleotide polymorphisms (SNPs) as instrumental variables, and the Inverse Variance Weighted (IVW) method for primary analysis. …”
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Prognostic Significance of Elevated Platelet Count (>200 x 10^9 per L) in BCLC Stages B and C of Hepatocellular Carcinoma: A Retrospective Multicenter Analysis by Munker S, Rodriguez I, Bernhart K, Ben Khaled N, Findik M, Siegmund LK, Ye L, Reiter FP, Roessler D, Nasseh D, Balcar L, Pomej K, Scheiner B, Weiss C, Pinter M, Seidensticker M, Mayerle J, Philipp AB, De Toni EN

“…However, recent evidence suggests that elevated platelet count may also predict worse outcomes in advanced stages, suggesting a stage-dependent prognostic impact.Aim: This study evaluated the prognostic role of platelet counts across BCLC stages, adjusted for portal hypertension, to improve individualized patient management.Methods: In this retrospective, multicenter study, platelet count of 1112 patients with HCC in different tumor stages was analyzed. …”
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Acupuncture as adjunctive therapy for acute cerebral infarction: a randomized clinical trial by Jiang-Peng Cao, Jiang-Peng Cao, Jiang-Peng Cao, Xin-Yue Du, Xiao-Xi Liu, Xiao-Xi Liu, Meng-Han Li, Meng-Han Li, Man Zhang, Sheng-Xuan Guo, Sheng-Xuan Guo, Qiu-Han Cai, Qiu-Han Cai, Jia-Xin Zhang, Jia-Xin Zhang, Jia-Xin Zhang, Shan-Shan Sun, Shan-Shan Sun, Shan-Shan Sun, Jia-Wei Han, Lin-Ling Chen, Na Zheng, Lan-Yu Jia, Gui-Ping Li, Gui-Ping Li, Yuan-Hao Du, Yuan-Hao Du

“…We aimed to investigate the efficacy and safety of acupuncture as adjunctive therapy to improve neurological function in patients with ACI.MethodsThe multicenter, sham-controlled, patient- and assessor-blinded randomized controlled trial was conducted in 4 tertiary hospitals in China from January to September 2024. …”
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Can Synthetic Data Allow for Smaller Sample Sizes in Chronic Urticaria Research? by Annika Gutsche, Pascale Salameh, Samad S. Jahandideh, Mehran Roodsaz, Serkan Kutan, Ali Salehzadeh‐Yazdi, Emek Kocatürk, Stamatios Gregoriou, Simon F. Thomsen, Kanokvalai Kulthanan, Papapit Tuchinda, Joachim Dissemond, Alicja Kasperska‐Zajac, Magdalena Zajac, Mateusz Zamłyński, Martijn vanDoorn, Claudio A. S. Parisi, Jonny G. Peter, Cascia Day, Cathryn McDougall, Michael Makris, Daria Fomina, Elena Kovalkova, Nikolai Streliaev, Gerelma Andrenova, Marina Lebedkina, Maryam Khoskhkui, Mehraneh M. Aliabadi, Andrea Bauer, Lea Kiefer, Melba Muñoz, Karsten Weller, Pavel Kolkhir, Martin Metz

“…Smaller subgroups of the data were equally replicated and followed the same distribution as RWD. …”
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Key indicators for guiding tocilizumab therapy to prevent orbital decompression surgery in hormone-resistant dysthyroid optic neuropathy by Wenjun Shu, Wenjun Shu, Wenjun Shu, Wenjun Shu, Mingxu Yan, Mingxu Yan, Mingxu Yan, Mingxu Yan, Lu Gan, Lu Gan, Lu Gan, Lu Li, Hongyue Tao, Zhiyu Peng, Zhiyu Peng, Zhiyu Peng, Zhiyu Peng, Jinghan Wang, Jinghan Wang, Jinghan Wang, Xiaofeng Li, Xiaofeng Li, Xiaofeng Li, Xintong Lin, Xintong Lin, Xintong Lin, Haifeng Chen, Haifeng Chen, Haifeng Chen, Jie Guo, Jie Guo, Jie Guo, Kang Xue, Kang Xue, Kang Xue, Hongguang Cui, Heng Lou, Heng Lou, Heng Lou, Binbin Xu, Binbin Xu, Binbin Xu, Jinwei Cheng, Jinwei Cheng, Jinwei Cheng, Hongying Ye, Yiming Li, Jiang Qian, Jiang Qian, Jiang Qian, Rui Zhang, Rui Zhang, Rui Zhang, Ruiqi Ma, Ruiqi Ma, Ruiqi Ma, Fangfang Zeng

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Development and validation of a predictive nomogram for differentiating diabetic nephropathy from non-diabetic nephropathy in patients with T2DM: a multicenter study by Zishan Lin, Zishan Lin, Zishan Lin, Tao Hong, Tao Hong, Tao Hong, Wenfeng Wang, Wenfeng Wang, Wenfeng Wang, Shidong Xie, Shidong Xie, Shidong Xie, Caiming Chen, Caiming Chen, Caiming Chen, Feng Yang, Dewen Jiang, Dewen Jiang, Dewen Jiang, Jianxin Wan, Jianxin Wan, Jianxin Wan, Zugang Xie, Yanfang Xu, Yanfang Xu, Yanfang Xu

“…This multicenter study aims to develop a non-invasive diagnostic model to distinguish DN from NDN in T2DM patients.MethodsFrom January 2014 to December 2023, T2DM patients undergoing percutaneous renal biopsies at three hospitals in Fujian were enrolled. …”
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Improving health-promoting workplaces through interdisciplinary approaches. The example of WISEWORK-C, a cluster of five work and health projects within Horizon-Europe by Deborah De Moortel, Michelle C Turner, Ella Arensman, Alex Binh Vinh Duc Nguyen, Víctor Gonzalez

“…The project is a collaboration between five countries (Austria, Belgium, Greece, the UK, and Sweden) and entails a cross-national mixed-methods intervention study with an embedded process and impact evaluation. …”
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Reconstruction of a lncRNA-Associated ceRNA Network in Endothelial Cells under Circumferential Stress by Zhuhui Huang, William Adiwignya Winata, Kui Zhang, Yang Zhao, Yang Li, Ning Zhou, Shaoyou Zhou, Wei Fu, Bokang Qiao, Guoqi Li, Yihui Shao, Jubing Zheng, Ran Dong

“…We constructed and visualized a lncRNA-miRNA-mRNA network, and the top 20 nodes are identified after calculating their degrees. …”
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