Evaluation of the therapeutic effect of repeated photodynamic therapy-assisted SRP treatments on class II furcation by Yikuan Wu, Haoyu Li, Yixiang Wang, Beiying Zhang, Chunsheng Bi, Xiaojun Li

“…Subgingival microbiota was analyzed via 16S rRNA sequencing, while patient-reported outcomes (PROs) included Visual Analog Scale (VAS) and oral health impact (OHIP-14). …”
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Comparison of two portable metabolic systems for measuring energy expenditure at rest and during exercise in untrained women by Feng Gao, Feng Gao, Feng Gao, Yujing Chan-Yu, Yujing Chan-Yu, Zhi Li, Zhi Li, Yongfu Liu, Yongfu Liu, Fei Liu, Fei Liu, Di Liu, Wenjun Yu, Wenjun Yu, Weiwei Chen, Junhua Wang, Junhua Wang, Junhua Wang, Shenglong Le, Shenglong Le, Shenglong Le

“…Agreement between the two systems was evaluated by calculating Pearson correlation coefficients and visually examining Bland–Altman plots.ResultsThe number of participants who completed resting and exercise measurements was 18 and 19, respectively. …”
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Agarwood Chromone Alleviates Gastric Ulcers by Inhibiting the NF-κB and Caspase Pathways Based on Network Pharmacology and Molecular Docking by Canhong Wang, Yulan Wu, Bao Gong, Junyu Mou, Xiaoling Cheng, Ling Zhang, Jianhe Wei

“…Finally, binding of the core compounds to the key targets was verified via molecular docking and visualized. <b>Results:</b> The pharmacological results show that the CHRs reduced the gastric occurrence and ulcer inhibition rates by up to more than 70% in a dose-dependent manner. …”
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The oncolytic avian reovirus p17 protein suppresses invadopodia formation via disruption of TKs5 complexes and oncogenic signaling pathways by Chao-Yu Hsu, Jyun-Yi Li, Jyun-Yi Li, Wei-Ru Huang, Wei-Ru Huang, Tsai-Ling Liao, Tsai-Ling Liao, Hsiao-Wei Wen, Chi-Young Wang, Chi-Young Wang, Lon-Fye Lye, Brent L. Nielsen, Hung-Jen Liu, Hung-Jen Liu, Hung-Jen Liu, Hung-Jen Liu, Hung-Jen Liu

“…Furthermore, invadopodia detection, gelatin degradation assay, and Fluorescence imaging was performed to visualize invadopodia structures and assess extracellular matrix degradation. …”
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Comparing the Effectiveness of Self-Compassion and Mindfulness Therapies on Affection Control of Poor Parenting Adolescents by Zahra EffatDoost Sani, Mohammad Reza Zarbakhsh Bahri, Alireza Homayuni

“…Therefore, based on the results, the assumption of variance equality was accepted. In M-Box assumption also, the equality of variance- covariance was not accepted (p>0.001). …”
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Anti-VEGF drugs compared with laser photocoagulation for the treatment of proliferative diabetic retinopathy: a systematic review and individual participant data meta-analysis by Mark Simmonds, Alexis Llewellyn, Ruth Walker, Helen Fulbright, Matthew Walton, Rob Hodgson, Laura Bojke, Lesley Stewart, Sofia Dias, Thomas Rush, João Pereira Figueira, Sobha Sivaprasad, John G Lawrenson, Tunde Peto, David Steel

“…Key outcomes were best corrected visual acuity, diabetic macular oedema and vitreous haemorrhage. …”
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Non-Invasive Ventilation Failure in Pediatric ICU: A Machine Learning Driven Prediction by Maria Vittoria Chiaruttini, Giulia Lorenzoni, Marco Daverio, Luca Marchetto, Francesca Izzo, Giovanna Chidini, Enzo Picconi, Claudio Nettuno, Elisa Zanonato, Raffaella Sagredini, Emanuele Rossetti, Maria Cristina Mondardini, Corrado Cecchetti, Pasquale Vitale, Nicola Alaimo, Denise Colosimo, Francesco Sacco, Giulia Genoni, Daniela Perrotta, Camilla Micalizzi, Silvia Moggia, Giosuè Chisari, Immacolata Rulli, Andrea Wolfler, Angela Amigoni, Dario Gregori

“…The RF model demonstrated the highest AUROC and sensitivity equal to 0.83 (0.64, 0.94). Base excess, weight, age, systolic blood pressure, and fraction of inspired oxygen were identified as the most predictive features. …”
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Development and external validation of a nomogram prediction model based on quantitative coronary angiography for predicting ischemic lesions: a multi-centre study by Shuai Yang, Shuai Yang, Shuang Leng, Shuang Leng, Zhouchi Wang, Jiang Ming Fam, Jiang Ming Fam, Adrian Fatt Hoe Low, Adrian Fatt Hoe Low, Ru-San Tan, Ru-San Tan, Ping Chai, Ping Chai, Lynette Teo, Lynette Teo, Chee Yang Chin, Chee Yang Chin, John C. Allen, Mark Yan-Yee Chan, Mark Yan-Yee Chan, Khung Keong Yeo, Khung Keong Yeo, Aaron Sung Lung Wong, Aaron Sung Lung Wong, Soo Teik Lim, Soo Teik Lim, Qinghua Wu, Liang Zhong, Liang Zhong, Liang Zhong

“…An external validation (n = 107 patients) was performed to assess the nomogram model's discrimination and consistency.ResultsLesion length, minimal lumen diameter, stenosis flow reserve, percent diameter stenosis by visual estimation, and weight were included as predictors in the nomogram. …”
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Adolescents and adults with FOXP1 syndrome show high rates of anxiety and externalizing behaviors but not psychiatric decompensation or skill loss by Tess Levy, Tess Levy, Hailey Silver, Hailey Silver, Renee Soufer, Renee Soufer, Audrey Rouhandeh, Audrey Rouhandeh, Audrey Rouhandeh, Alexander Kolevzon, Alexander Kolevzon, Alexander Kolevzon, Alexander Kolevzon, Joseph D. Buxbaum, Joseph D. Buxbaum, Joseph D. Buxbaum, Joseph D. Buxbaum, Joseph D. Buxbaum, Joseph D. Buxbaum, Paige M. Siper, Paige M. Siper, Paige M. Siper

“…To date, much of the literature focuses on childhood symptoms and little is known about the FOXP1 syndrome phenotype in adolescence or adulthood.MethodsA series of caregiver interviews and standardized questionnaires assessed psychiatric and behavioral features of 20 adolescents and adults with FOXP1 syndrome. …”
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Three-Dimensional-Printed Isoniazid Chewable Gels for On-Demand Latent Tuberculosis Treatment in Children by Amanda de O. E. Moreira, Lêda Maria S. Azevedo Neta, Márcia Pietroluongo, Ana Paula dos S. Matos, Beatriz B. Correa, Beatriz H. Ortiz, André da S. Guimarães, Marcio Nele, Carollyne M. Santos, Ana Elizabeth C. Fai, Maria Helena Gonçalves, Flávio M. Shimizu, Monique S. Dos Santos, Rosemberg B. Moure, Diogo D. Nascimento, André Luis de A. Guimarães, Saint Clair dos S. G. Junior, Alessandra L. Vicosa, Lucio M. Cabral

“…This study aims to develop innovative 3D-printed chewable gels containing INH for LTBI treatment. <b>Methods</b>: The gels were formulated using gelatin and carrageenan gum, sugar-free sweeteners, and flavoring. …”
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Multimodal abnormalities of brain function in chronic low back pain: a systematic review and meta-analysis of neuroimaging studies by Xingyao Chen, Xingyao Chen, Xingyao Chen, Nuo Chen, Nuo Chen, Nuo Chen, Peng Lai, Peng Lai, Yiqi Sun, Jie Yu, Ming Xin, Deliang Zhu, Fanrong Liang, Fanrong Liang, Fanrong Liang, Qian Song, Shirui Cheng, Shirui Cheng, Shirui Cheng, Zhengjie Li, Zhengjie Li, Zhengjie Li, Zhengjie Li

“…In this meta-analysis, we integrated the existing data, delineating a pattern of coherent results from the encompassed studies.MethodsA systematic search of neuroimaging studies investigating the brain activity differences between CLBP and Healthy controls (HCs) was conducted in seven databases up to December 22, 2024. …”
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Study on the risk factors for colorectal polyp recurrence: a cross-sectional retrospective cohort study by Fang Li, Fang Li, Mengge Lu, Mengge Lu, Bo Xu, Zheng Xiang, Zheng Xiang, Yuan Zhang, Yuan Zhang, Boran Cao, Xuewei Li, Xuewei Li, Yanan Wu, Yanan Wu, Rongrong Zheng, Rongrong Zheng, Qin Cai, Qin Cai, Jun Shen, Pengfei Xin, Pengfei Xin, Lianbo Xiao, Lianbo Xiao, Yanqin Bian, Yanqin Bian

“…Patients with a risk prediction model value greater than or equal to 0.44 have increased odds to experience postoperative recurrence.…”
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Prevalence of cardiovascular diseases and risk factor assessment in breast cancer survivors exposed to cardiotoxic therapy by Marina V. Vitsenya, Irina V. Barinova, Nana V. Pogosova, Tatevik A. Terteryan, David T. Kuchiev, Yulia V. Khrushcheva, Anna A. Gerasimova, Anastasiya Y. Filatova, Nursiyat M. Ibragimova, Olga O. Frolkova, Fail T. Ageev

“…The patients were examined for CVDs and their risk factors, with assessment of clinical status, serum lipids, glucose, creatinine, and C-reactive protein, levels of physical activity (International Physical Activity Questionnaire), stress (Visual Analog Scale), anxiety and depression (Hospital Anxiety and Depression Scale, HADS), and sleep quality (Pittsburgh Sleep Quality Questionnaire). …”
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CT-SEGMENTED BONE SUV IN MULTIPLE MYELOMA: A COMPARATIVE STUDY OF ¹⁸F-FDG AND ⁶⁸GA-PSMA PET/CT by Alexandre Mercuri Barbosa, Maria Emília Seren Takahashi, Stephan Pinheiro Macedo Souza, Edna Marina Souza, Sérgio Querino Brunetto, Cármino Antonio de Souza, Irene Gyongyver Heidemarie Lorand-Metze, Celso Darío Ramos

“…Materials and Methods: The study included ¹⁸F-FDG and ⁶⁸Ga-PSMA PET/CT images acquired within a 1- to 8-day interval from 15 patients (53% male, mean age 66.7 ± 10.7 years) with symptomatic, biopsy-proven MM. …”
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Prevalence and associated factors of syphilis among female sex workers in East Africa: a systematic review and meta-analysis by Solomon Gedfie, Woldeteklehymanot Kassahun, Abdu Jemal, Muluken Gashaw, Alembante Bazezew, Marye Nigatie, Getinet Kumie, Tadesse Misganaw, Zewdu Tefera, Bewuketu Belete Alemu, Bahriew Mezgebu, Brhanu Kassanew, Ephrem Tamrat, Wagaw Abebe, Agenagnew Ashagre, Assefa Sisay, Yalewayker Gashaw, Melese Abate Reta, Melese Abate Reta

“…Publication bias was evaluated visually using funnel plots and statistically through Egger’s weighted regression test.ResultsA total of 16,456 articles were retrieved, among which 24 studies involving 25,979 female sex workers were included in the final meta-analysis. …”
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Comparison of Endoscopic Unilateral Laminectomy for Bilateral Decompression (Endo‐ULBD) and Posterior Lumbar Interbody Fusion (PLIF) in Managing Multi‐Segmental Lumbar Spinal Steno... by Kunpeng Su, Qingyu Yao, Mingzhi Liu, Sheng Chang, Mengxuan Wang, Antao Lin, Guantong Sun, Yichen Jiang, Shengwei Meng, Hao Zhang, Wentao Liu, Hongtao Ge, Zengjie Wu, Zirui Wang, Derong Xu, Chuanli Zhou

“…Clinical outcomes were evaluated using the Visual Analog Scale (VAS), the Japanese Orthopedic Association (JOA) score, and the Oswestry Disability Index (ODI), which were assessed preoperatively and at follow‐up. …”
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Variation in Mesopic Retinal Sensitivity Relative to Distance from Geographic Atrophy in Age-Related Macular Degeneration by Souvick Mukherjee, PhD, Emily Vance, MPH, Leon von der Emde, MD, Thilaka Arunachalam, BS, Tharindu De Silva, PhD, Alisa T. Thavikulwat, MD, Christine Orndahl, PhD, Caroline Nyaiburi, MS, Maria Abraham, ScM, Keri Hammel, MS, SriniVas R. Sadda, MD, Emily Y. Chew, MD, Maximilian Pfau, MD, PhD, Wai T. Wong, MD, PhD, Brett G. Jeffrey, PhD, Tiarnán D.L. Keenan, BM BCh, PhD

“…Overall, the degree and extent of decreased visual function beyond GA borders have important implications for the design of clinical trials, decision-making in clinical practice, and insights into AMD pathophysiology. …”
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Automated Quantification of Retinopathy of Prematurity Stage via Ultrawidefield OCT by Spencer S. Burt, BA, Aaron S. Coyner, PhD, Elizabeth V. Roti, BS, Yakub Bayhaqi, PhD, John Jackson, MD, Mani K. Woodward, MS, Shuibin Ni, PhD, Susan R. Ostmo, MS, Guangru Liang, BS, Yali Jia, PhD, David Huang, MD, Michael F. Chiang, MD, Benjamin K. Young, MD, Yifan Jian, PhD, John Peter Campbell, MD

“…Purpose: Retinopathy of prematurity (ROP) stage is defined by the visual appearance of the vascular-avascular border, which reflects a spectrum of pathologic neurovascular tissue (NVT). …”
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Clinical effect of external application of Rutongyu medicine film in the treatment of hyperplasia of mammary gland (乳痛愈药膜治疗乳腺增生病临床疗效观察) by HAN Jianping (韩建萍), LI Ying (李影), HOU Pengxiao (候朋晓), ZHANG Ning (张宁), REN Yaxing (任亚星), LIU Haihan (刘海涵), DAI Wei (代巍), ZHANG Chunyan (张春艳), YUE Yuzi (岳玉姿), LI Yiliang (李以良), TANG Ling (唐玲)

“…Objective To observe the clinical effect of external application of Rutongyu medicine film in the treatment of hyperplasia of mammary gland. Methods Totally 96 patients with hyperplasia of mammary gland were randomly divided into the treatment group (n=48) and control group (n=48). …”
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Exploring the efficacy and safety of Yu-Ping-Feng powder with variation against allergic rhinitis: a randomized, double-blind, placebo-controlled trial by Zhi-Xiu Lin, Tin Muk Ho, Yan-Fang Xian, Kam Leung Chan, Qing-Qing Xu, Cho Wing Lo, Justin Che Yuen Wu, Kam Lun Hon, Sin Bond Leung, Chon Pin Chia, Chi Him Sum, Tak Yee Chow, Pui Kuan Cheong, Jessica Yuet Ling Ching, Hongwei Zhang, Ka Chun Leung, Wai Ling Lin

“…Purpose To evaluate the efficacy and safety of YPV on AR patients with the lung and spleen Qi deficiency type using a randomized, double-blind, placebo-controlled clinical trial (RCT). Study design and methods Between April 2022 and June 2023, a total of 58 participants were recruited and randomly allocated to receive either YPV (n = 29) or placebo (n = 29) for 8 consecutive weeks. …”
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