A Comparison of the Effects of Sevoflurane, Propofol, and Propofol Combined with Butorphanol in Suppressing Sufentanil-Induced cough—A Randomized Controlled Trial by Ji H, Zhang F, Yang M, Xu X, Sun Y, Xia X, Li Y

“…Haoyu Ji,1,* Fazhong Zhang,2,* Ming Yang,1 Xiaomei Xu,1 Yuanming Sun,1 Xiaoqiong Xia,1,* Yuanhai Li2 1Anesthesiology Department, Chaohu Hospital Affiliated with Anhui Medical University, ChaoHu, Hefei, People’s Republic of China; 2Anesthesiology Department, The First Affiliated Hospital of AnHui Medical University HeFei, People’s Republic of China*These authors contributed equally to this workCorrespondence: Xiaoqiong Xia, Anhui Province. …”
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Mapping the Brain’s Role in Osteoarthritis: New Evidence for Prevention by Di J, Xi Y, Liu Y, Qi L, Chen S, Qin Y, Xiang C

“…Jingkai Di,1,2,* Yujia Xi,3,* Yaru Liu,4 Likun Qi,3 Shuai Chen,1,2 Yingda Qin,3 Chuan Xiang1,2 1Department of Orthopedics, Second Hospital of Shanxi Medical University, Taiyuan, People’s Republic of China; 2Shanxi Provincial Key Laboratory of Bone and Soft Tissue Injury Repair, Taiyuan, People’s Republic of China; 3The Second Hospital of Shanxi Medical University, Taiyuan, People’s Republic of China; 4The Third Hospital of Shanxi Medical University, Taiyuan, People’s Republic of China*These authors contributed equally to this workCorrespondence: Chuan Xiang, Department of Orthopedics, Second Hospital of Shanxi Medical University, Taiyuan, People’s Republic of China, Tel +86 15903410351, Email chuanxiang@sxmu.edu.cnPurpose: This study explores the causal link between brain structural parameters and Osteoarthritis (OA), aiming to prevent OA progression.Patients and Methods: We used two-sample Mendelian randomization. …”
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A Randomized Controlled Trial for the Optimal Implementation of Psoriasis Treatment by Integrating Chinese and Western Medicine by Yu Y, Sun X, Hu R, Xia P, Wei Y, Yang W, Huang N, Ding Y, Guo S, Yang C, Weng H, Zhang Y, Ding X, Huang Q, Zhou X, Li X, Li B

“…Currently, the prevalent guideline-recommended regimen is based on psoriasis severity; however, no corresponding studies have been conducted on the hierarchical selection of integrated Chinese and Western medicine treatments.Objective: To explore the optimal implementation of psoriasis treatment by integrating Chinese and Western medicine.Methods: We conducted a 16-week multicenter single-blind randomized controlled trial in China between December 2019 and July 2022. …”
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Effects of alginate oligosaccharides on depression-like behavior and gut microbiota in zebrafish induced by chronic unpredictable mild stress by LONG Yan, SHI Yanxia, QIU Yue, NONG Huiting, ZHU Wuchang, SU Hongmei, HE Naihuan, QIN Zhuwen, WEI Jinbin

“…Except for the normal and model groups, which were given equal volumes of rearing water, the remaining groups were immersed in the corresponding concentrations of AOS for 60 min daily starting from day 8. …”
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Long COVID in Elderly COPD Patients: Clinical Features, Pulmonary Function Decline, and Proteomic Insights by Li S, Zhao H, Zhang M, Yuan T, Chai D, Shen Z, Qin C, Li Y, Pan M

“…Shuangyan Li,1,* Hui Zhao,2,* Min Zhang,3 Tingting Yuan,4 Di Chai,5 Zhengyin Shen,3 Chengfeng Qin,2,6 Yanming Li,5 Mingming Pan5 1Beijing Hospital, National Centre of Gerontology, Institute of Geriatric Medicine, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, People’s Republic of China; 2State Key Laboratory of Pathogen and Biosecurity, Academy of Military Medical Sciences, Beijing, People’s Republic of China; 3Department of Radiology, Beijing Hospital, National Center of Gerontology, Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, Beijing, People’s Republic of China; 4Department of Clinical Laboratory, Beijing Hospital, National Center of Gerontology, Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, Beijing, People’s Republic of China; 5Department of Respiratory and Critical Care Medicine, Beijing Hospital, National Center of Gerontology, Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, Beijing, People’s Republic of China; 6Research Unit of Discovery and Tracing of Natural Focus Diseases, Chinese Academy of Medical Sciences, Beijing, People’s Republic of China*These authors contributed equally to this workCorrespondence: Mingming Pan, Department of Respiratory and Critical Care Medicine, Beijing Hospital, National Center of Gerontology, Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, No. 1 Dongdan Dahua Road, Beijing, People’s Republic of China, Tel +86-13661129402, Email panmm6@163.comBackground: Elderly patients with chronic obstructive pulmonary disease (COPD) face a heightened risk of developing long coronavirus disease (COVID); however the exact clinical characteristics and underlying mechanisms remain unclear.Methods: We enrolled 85 elderly COPD patients, of whom 43 reported newly onset persistent fatigue (the most dominant complaint of long COVID) within 1 year after severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, and they were allocated to the Long-COVID group. …”
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Biomechanical Corneal Parameters in Eyes With Chronic Ocular Hypotony and in Non-Hypotonic Eyes. Self-Controlled Case Series Study by Bouchikh-El Jarroudi R, Roche Fernández K, Romera Romero P, Croitoru-Croitoru T, Goñi-Guarro A, Botella-Garcia J, Sabala Llopart A, Loscos-Arenas J, Videla S

“…Our purpose is to provide evidence and clinical correlation on the biomechanical corneal changes in chronic hypotonic eyes.Patients and Methods: A single-center, transversal, self-controlled case series study was conducted involving patients with at least one chronic hypotonic eye (defined as an intraocular pressure ≤ 6.5 mmHg measured on three separate occasions for at least three months). …”
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Usp18 Mediates D-Dopachrome Tautomerase-Induced Astrocytic Inflammation After Spinal Cord Injury by Zhang X, Hou Y, Cai R, Zhou Y, He B, Cao Z, Li A, Song H, Wang Y, Jiang H, Qi L, Wang Y

“…Whether D-DT activates astrocytic inflammation via regulation of Usp18 deserves further study.Methods: SCI model was prepared by cord contusion at T8-T10 of rats. …”
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Changes of natriuresis and prediction of cardiovascular events in patients with type 2 diabetes and decompensated heart failure over therapy with sodium-glucose cotransporter 2 inh... by O. A. Abdullaev, A. G. Arutyunov, D. P. Vereshchak, E. V. Tavlueva, V. A. Konik, N. A. Bylova, D. V. Puzenko, N. P. Kulagina, I. R. Nurieva, T. V. Zanina, G. P. Arutyunov

“…Dapagliflozin (D), like empagliflozin (E), significantly and equally increases the level of natriuresis (D +108,25±13,56 mmol/day, p<0,001, E +112,52±8,50, p=0,00009) and reduces the extracellular fluid volume (D -5,05±1,46 kg, p<0,001, E -5,69±2,47, p<0,001) on day 5.Conclusion. …”
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Impact of Pan-Immune Inflammation Value on Short-Term Outcomes and Long-Term Prognosis in Patients with Type A Aortic Dissection by Cai H, Shourav, Shao Y, Shuangling S, Duan C, Zhang C, Wu QC

“…This study aims to investigate the relationship between preoperative PIV and both short-term and long-term outcomes in patients with acute TAAD.Methods: This retrospective study included acute TAAD patients who underwent surgical repair between September 2017 and December 2020. …”
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The Role of Applying Metagenomic Next-Generation Sequencing (mNGS) in Periprosthetic Joint Infection with Sinus Tract: A Retrospective Study by Yuan X, Wang Q, Ding H, Li H, Fang X, Zhang W, Huang Z

“…We evaluated mNGS’s role in diagnosing and guiding treatment for PJI with sinus tracts.Methods: This retrospective analysis included 52 PJI patients (2019– 2024). …”
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Development and Validation of the CHD-PEBBS: A Scale to Assess Perceived Exercise Benefits and Barriers in Coronary Heart Disease Patients by Liu Y, Feng L, Wang L, Li H, Tu H, Li X, Zhang X, Zhang L, Yang M, Sun X, Huang T, Xiong Y

“…There is a lack of validated tools to assess coronary heart disease (CHD) patients’ exercise perception.Purpose: The aim of this study is to develop a scale assessing CHD patients’ perceived exercise benefits and barriers (CHD-PEBBS) and test its reliability and validity.Methods: A total of 205 CHD patients were recruited for a cross-sectional survey. …”
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Perspectives on Enhanced Measurement-Based Care Among Healthcare Providers, Adults, Adolescent Patients with Major Depressive Disorder and Pediatric Family Members: A Multicenter O... by Zhang H, Sun P, Wang X, Yang X, He Y, Yang T, Su Y, Fu Y, Li Q, Sun J, Liu J, Murphy JK, Michalak EE, Lam RW, Chen J, Fang Y

“…This study aimed to identify the barriers and facilitators of enhanced MBC (eMBC) in the outpatient setting to clarify the eMBC utilization dilemma.Methods: Between September 2022 and June 2023, we collected the opinions of healthcare providers, adult and adolescent patients, and family members of adolescent patients via online surveys. …”
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СРАВНЕНИЕ ВЛИЯНИЯ ДЛИТЕЛЬНОЙ ТЕРАПИИ, ОСНОВАННОЙ НА КАРВЕДИЛОЛЕ И БИСОПРОЛОЛЕ, НА МЕТАБОЛИЧЕСКИЕ ПАРАМЕТРЫ И ЭРЕКТИЛЬНУЮ ФУНКЦИЮ У БОЛЬНЫХ АРТЕРИАЛЬНОЙ ГИПЕРТОНИЕЙ И ИЗБЫТОЧНОЙ МАС... by S. Y. Martsevich, S. N. Tolpygina

“…Aim — to compare the antihypertensive efficacy, effect on blood glucose, uric acid, index of insulin resistance levels, lipid profile and effect on erectile function of long-term therapy, based on carvedilol and bisoprolol in patients with AH 1−2 deg. and overweight/obesity.Materials and methods. Type of research: clinical, multicenter, randomized, open, comparative, stepped, in two parallel groups. …”
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Efficacy and Safety of Bushen Jiedu Tongluo Decoction in Active Rheumatoid Arthritis: Study Protocol for a Multi-Center, Randomized, Double-Blind, Controlled Trial by He Y, Shen J, Wu H, Chen L, Zhou Q, Wang Q, Guo Y, Wu F, Pan X

“…Therefore, we designed a multi-center, randomized, double-blind, placebo-controlled study, to scientifically evaluate the clinical efficacy and safety of BSJDTL for active RA.Methods: This was a multi-center, randomized, double-blind placebo-controlled trial. …”
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A New Strategy for the Treatment of Patients With Prolonged Impairment of Consciousness Using Xenon. Prospective Pilot Study by A. I. Shpichko, A. N. Kuzovlev, R. A. Cherpakov, N. P. Shpichko, O. A. Grebenchikov, A. K. Yevseyev, A. K. Shabanov, S. S. Petrikov

“…Patients were randomized into two equal groups. In group I (comparisons, n=15) (in addition to the standard treatment after a traumatic brain injury), each patient included in the study underwent 7 sessions of inhalation of an air-oxygen mixture with an oxygen content of at least 30 vol% for 30 minutes. …”
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COMPARATIVE EVALUATION OF THE LABORATORY STUDY RESULTS OF THE ADHESION STRENGTH OF A-SILICONE LINING MATERIAL IN THE PRODUCTION OF TWO-LAYER REMOVABLE PROSTHESES by I. Yanishen, P. Zapara, О. Fedotova

“…However, it was found that the index of the bond strength of the "PM-S" with the plastic "Pallopress" is equal to (5.5 ± 0.3) kgf / cm2, which is significantly (p <0,05) higher than the contact the material is "Villacryl H Plus" - (5.1 ± 0.2) kgf / cm2. …”
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Effect of Resistance Training on Hepatic Bile Acid, beta-Klotho Protein and Expression of Farnesoid X Receptor, Fibroblast Growth Factor 15 and Fibroblast Growth Factor Receptor 4... by Mehri Gholipour, Najme Rezaeian, Mohammad Karimi, Sadegh Cheragh-Birjandi

“…This research was carried out to study the effect of eight weeks of resistance training on liver bile acid (BA), beta klotho protein (KLB) and the expression of farnesoid X receptor (FXR), fibroblast growth factor 15 (FGF15) and fibroblast growth factor receptor 4 (FGFR4) in male rats with non-alcoholic fatty liver disease. Materials and Methods: In this study, 16 male Wistar rats (age, six-weeks and weight, 120-160 gr) after induction of NAFLD conditions, with six weeks of high-fat diet were randomly divided into two equal groups (n=8 in each group) of Control (C), and resistance training (R). …”
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Adenovirus Nanoparticles Displaying RBD Induce a Protective Immune Response Against BA.5 in Mice by Mo C, Wang Z, Liu D, Yang X, Zhang Q, Ye L, Yuan S, Deng S, Lai Z, Huang D, Yang Y, Xu D, Yuan J, Zhu Y, Liu H, Zhou C, Liao X, Li X, Liu W, Zhou R, Tian X

“…Hexon is the major capsid protein, and multiple hypervariable regions (HVRs) have been used for displaying exogenous antigens and inducing a strong antibody responses.Methods: We utilized SpyCatcher/SpyTag technology to incorporate SpyTag into HVR2, 4, and 7 of the hexon of the bivalent vaccine strain rAd3/7, respectively, to construct recombinant Ad, rAd3/7-SpyTag. …”
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Prognostic Implications of Red Blood Cell Distribution Width to Albumin Ratio in Myelofibrosis: A 10-Year Multicenter and Retrospective Study by Zeng T, Zheng Z, Qian H, Liu L, Shi X, Shao Y, Huang Z, Li R, Wen B, Han Q, Feng Q, Tu L, Bao X, Tong H, Jin J, Huang J

“…The red cell distribution width to albumin ratio (RAR), a novel biomarker indicative of inflammation, has emerged as a strong prognostic indicator in the general population but remains unexplored in MF.Methods: We retrospectively enrolled 504 consecutive MF patients from 7 hematological centers over a 10-year period. …”
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Abstract 062: N20 Potential And Imaging Biomarkers Of Functional Recovery In Acute Ischemic Stroke Patients And EVT by Alicia Martinez Piñeiro, Giuseppe Lucente, María Hernandez‐Perez, Jordi Cortés, Andrea Arbex, Meritxell Gomis Cortina, Laura Dorado Bouix, Natalia Pérez de la Ossa, Alba Ramos‐Fransi, Miriam Almendrote, Carlos Castaño, Sebastián Remollo, Maria Rosa García Sort, Patricia Cuadras Collsamata, Mónica Millán, Antoni Dávalos

“…This secondary study aims to describe the association between the N20 response and imaging biomarkers of ischemic penumbra, infarct volume and collateral flow. Methods Presence and amplitude of the N20 response was recorded before EVT. …”
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