The study of functional asymmetry in students and schoolchildren practicing martial arts by Vyacheslav V. Romanenko, Olha O. Podrihalo, Leonid V. Podrigalo, Sergii S. Iermakov, Zhanna V. Sotnikova-Meleshkina, Oksana V. Bobrova

“…The functional asymmetry was determined using «Reaction SM Dual» software for tablets with iOS. Two visual tests were used. The duration of each test was 100 s. …”
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The efficacy of core stabilization exercise in mild and moderate adolescent idiopathic scoliosis: a systematic review and meta-analysis by Xiaomei Liu, Yanyang Wang, Min Liu, Yu Zhang, Qiang Wu, Qian Wang

“…Cobb angle, angle of trunk rotation, apical vertebral rotation, Walter Reed Visual Assessment Scale, Posterior Trunk Symmetry Index, forced vital capacity (FVC), forced expiratory volume in 1 s (FEV1), FEV1/FVC, SRS-22,, were focused as outcomes. …”
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Reduction in Artemisia Pollen-Specific IgE Levels During House Dust Mite Allergen Immunotherapy in Polysensitized Allergic Rhinitis Patients: A Three-Year Retrospective Study in No... by Sun X, Li X, Gao T, Liu P, Liu N, Jin P, Zhi L

“…Clinical outcomes were also recorded, including Total Nasal Symptom Score (TNSS), Visual Analog Scale (VAS), and medication use.Results:  Over three years, SIgE levels for Der p significantly decreased (p = 0.0001), while Der f showed a slight and significant decrease (p = 0.0334). …”
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Study of anatomy-diagnostic features of leaves of <i>Cynara scolymus</i> L. grown under the conditions of the Kyrgyz Republic by S. C. Chubakova, N. T. Farmanova, N. V. Bobkova, T. A. Mamatov

“…To detect characteristic external features of artichoke prickly leaves, an external examination of the analytical sample was carried out visually (10 × ). Microscopic and histochemical examination was carried out in accordance with GF RF XV ed. …”
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Features of ankylosing spondylitis at different stages in men and women by I. A. Cherentsova, E. N. Otteva

“…For the calculation of enthesites, the validated index Maastricht Ankylosing Spondylitis Enthesitis Score (MASES) was used; pain intensity in the last week was estimated using a visual analogue scale (VAS). Laboratory examination included the determination of ESR and HLA-B27 antigen. …”
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Treatment Planning Strategies for Interstitial Ultrasound Ablation of Prostate Cancer by Pragya Gupta, Tamas Heffter, Muhammad Zubair, I-Chow Hsu, E. Clif Burdette, Chris J. Diederich

“…This involves the integration with a FDA 510(k) cleared catheter-based ultrasound interstitial applicators and delivery system. Methods: A 3D generalized &#x201C;prostate&#x201D; model was developed to generate temperature and thermal dose profiles for different applicator operating parameters and anticipated perfusion ranges. …”
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Spatiotemporal analysis of rainfall variability using satellite precipitation in watersheds by M.D. Syaifullah, A. Purwandani, M. Kudsy, Tukiyat , S. Tikno, A.E. Sakya, F.H. Widodo, S. Bahri, Muktiyono

“…Basic statistical analysis and mapping techniques are used to identify trends and visualize distribution patterns, aiming to provide insights into how natural landscape features influence rainfall behavior and water availability at the watershed scale.FINDINGS: The results reveal a significant long-term increase in rainfall in the Larona-Malili watershed, while no statistically significant trends are observed in the Brantas and Toba-Asahan watersheds. …”
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Hymecromone Administration in Real Clinical Practice: Results of the Prospective Multicentre Observational Study in the Republic of Kazakhstan by A. V. Nersesov, D. A. Kaybullaeva, V. S. Rakhmetova, I. A. Lozinskaya, A. K. Kurmangalieva, V. S. Ayupova, A. B. Orazbaeva, A. K. Kanabaeva, Yu. O. Shulpekova

“…The study included 2 patient visits and an intermediate telephone contact. A visual analogue scale and RAPID questionnaire were used to characterise biliary pain; severity of associated symptoms, bowel habit and a quality of life according the SF-12 were also assessed. …”
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Keratinocyte-derived VEGF-A is an essential pro-migratory autocrine mediator, acting through the KDR/GEF-H1/RhoA pathway by Vida Maksimoska, Vida Maksimoska, Qinghong Dan, Neetu Rambharack, Neetu Rambharack, Katalin Szászi, Katalin Szászi, Katalin Szászi, Katalin Szászi

“…The overall objective of the current study was to explore the connection between inflammation-induced keratinocyte mediator release and enhanced migration, and to identify specific RhoA regulators involved.MethodsThe study was done using HaCat cells and primary adult keratinocytes. …”
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A multicenter, prospective, randomized trial of the efficacy and safety of Alflutop® in an alternating dosing regimen versus the standard one. Communication 2: Evaluation of the ef... by E. P. Sharapova, L. I. Alekseeva, E. A. Taskina, N. G. Kashevarova, S. G. Anikin, E. A. Strebkova, A. M. Lila, V. I. Mazurov, N. A. Shostak, E. I. Shmidt, E. P. Ilivanova

“…From this point of view, therapy seems to be relevant when the latter involves drugs that have both symptom- and structure-modifying properties and have a high safety profile.Objective: to compare the safety of alternating and standard treatment regimens with Alflutop® in patients with knee OA.Patients and methods. 130 patients were enrolled in the trial who had Kellgren-Lawrence Grade II–III primary tibiofemoral knee OA with pain intensity on walking ≥40 mm on a visual analogue scale and who needed to take nonsteroidal anti-inflammatory drugs (≥30 days in the previous 3 months). …”
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Exploring Ocular Fundus Changes and Biochemical Correlations in Pregnancy-Induced Hypertension: Two Year Observational Study in Tertiary Care Center, India by A. M. Raja, G Seema

“…Each participant received a thorough ocular examination, which included visual acuity testing, anterior segment assessment, and fundus examination. …”
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Septal panniculitis as manifestation of COVID-19: own data by O. N. Egorova, R. G. Goloeva, D. I. Abdulganieva

“…Objective: to study the clinical and laboratory features of erythema nodosum (EN) in a cohort of patients with COVID-19 referred to a rheumatological center.Patients and methods. During 2020–2021 years 21 patients (18 women and 3 men, mean age 43.2±11.4 years) with EN and polyarthralgia/arthritis were examined. …”
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Evaluation of enhanced recovery after surgery combined with percutaneous acupoint electrical stimulation in perioperative nursing of patients with gastric cancer (快速康复护理联合经皮穴位电刺激在胃... by HUANG Yanying (黄艳颖), LI Wenjuan (李文娟)

“…The postoperative pain was evaluated by Visual Analogue Scale (VAS). The postoperative recovery indexes and postoperative complications were measured and analyzed. …”
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Comparative Analysis of ICS Combined with LABA versus Addition of Omalizumab on Transcriptomic Expression Profiles in Patients with Allergic Asthma by Liang YR, Chang CH, Huang SY, Wu YK, Yang MC, Huang KL, Tzeng IS, Hsieh PC, Lan CC

“…Therefore, this study aims to investigate the transcriptomic expression profiles and clinical outcomes between patients receiving ICS with LABA therapy and those adding omalizumab.Materials and Methods: This is a prospective, real-world study that enrolled 26 participants, divided into three groups: Group 1, ICS with LABA (n=10); Group 2, ICS with LABA plus omalizumab (n=12); and Group 3, healthy controls (n=4). …”
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PENURUNAN KADAR GULA DARAH AKIBAT PEMBERIAN EXTRA VIRGIN OLIVE OIL (Studi pada Tikus Galur Sprague Dawley yang Diinduksi Pakan Tinggi Lemak) by SH Bintari, K Nugraheni

“…It is caused by hyperglycemia induced by high-fat diet. Several alternative methods of treatment and prevention widely used is consuming olive oil. …”
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Comparison of the effects of remimazolam and dexmedetomidine on the quality of recovery in functional endoscopic sinus surgery: a randomized clinical trial by Yaqiong Li, Hui Zhou, Fanfan Gao, Qianqian Guan, Shengbin Wang, Yvqing Tan, Shenghong Hu

“…Group C received a placebo equal to dexmedetomidine. Anaesthesia was induced with propofol, sufentanil and cisatracurium. …”
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The Prognostic Value of Neutrophil-to-Lymphocyte Ratio and Lymphocyte-to-Monocyte Ratio in Patients with Hepatocellular Carcinoma Receiving HAIC-Based Conversion Hepatectomy: A Dua... by Li D, Fan Y, He B, Tang Y, Deng G, Guo R, Deng M, Tang D

“…This study evaluated the prognostic significance of neutrophil-to-lymphocyte ratio (NLR) and lymphocyte-to-monocyte ratio (LMR) in patients with HCC who received HAIC-based hepatectomy.Methods: This dual-center retrospective study included 390 patients who received HAIC-based conversion resection to investigate the relationship of NLR and LMR with survival outcomes, adverse events, and risk factors.Results: A total of 390 patients with HCC who received HAIC-based conversion liver resection were included. …”
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Restless Legs Syndrome Patients with Early Onset Disease or a Relevant Family History Associated with Pramipexole Ineffectiveness but Not Pregabalin by Ying M, Wang T, Zhang T, Zhai Z, Zhang L

“…Factors that affect medication efficacy remain unclear; different RLS subtypes may respond differently to various drugs.Objective: To identify factors associated with the ineffectiveness of pramipexole and pregabalin in patients with various subtypes of RLS.Methods: This retrospective nested case–control study enrolled 257 RLS patients prescribed pramipexole or pregabalin between March 2019 and April 2024 at the sleep center of Sir Run Run Shaw Hospital. …”
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Serum Osteopontin Enhances Hepatocellular Carcinoma Diagnosis and Predicts Anti-PD-L1 Immunotherapy Benefit by Wu M, Zou F, He S, Pi Y, Song Y, Chen S, Li L

“…Miantao Wu,1,2,&ast; Fei Zou,3,&ast; Suyin He,4,&ast; Yingqi Pi,5 Yiling Song,1,2 Shulin Chen,1,2 Linfang Li1,2 1State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-sen University Cancer Center, Guangzhou, People’s Republic of China; 2Department of Laboratory Medicine, Sun Yat-sen University Cancer Center, Guangzhou, People’s Republic of China; 3Department of Oncology, The First Affiliated Hospital of Chongqing Medical and Pharmaceutical College, Chongqing Key Laboratory of Prevention and Treatment for Occupational Diseases and Poisoning, Chongqing, People’s Republic of China; 4State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, People’s Republic of China; 5Department of Clinical Laboratory, The Seventh Affiliated Hospital, Sun Yat-sen University, Shenzhen, People’s Republic of China&ast;These authors contributed equally to this workCorrespondence: Linfang Li, State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-sen University Cancer Center, Guangzhou, 510060, People’s Republic of China, Email lilf@sysucc.org.cn Shulin Chen, State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-sen University Cancer Center, Guangzhou, 510060, People’s Republic of China, Email chenshl@sysucc.org.cnBackground: Osteopontin (OPN), a phosphorylated glycoprotein encoded by SPP1, critical in hepatic inflammation and fibrosis, requires further investigation for its role on hepatocellular carcinoma (HCC) and predictive value for anti-programmed cell death ligand 1 (anti-PD-L1) immunotherapy responses.Methods: Publicly available datasets were utilized to explore OPN expression in HCC. …”
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Adipose Tissue-Derived Extracellular Vesicles Loaded with miR-141-3p Regulate Obesity-Induced Insulin Resistance by Targeting Glycogen Synthesis and Gluconeogenesis by Wang Z, Ma T, Bai G, Fang Q, Ou B, Chen M, Xu P, Tian M, Xu A, Ma Y

“…This study aimed to investigate the regulatory effects of adipose tissue-derived EVs on obesity-induced hepatic insulin resistance and to elucidate the underlying molecular mechanisms by which EV-mediated signaling contributes to metabolic dysfunction.Methods: EVs with miR-141-3p knockout or overexpression were constructed and administered to both in vitro cell models and in vivo mouse models to investigate the regulatory role and underlying mechanisms of miR-141-3p-mediated adipose tissue-derived EVs in obesity-induced hepatic insulin resistance.Results: miR-141-3p is significantly upregulated in adipose tissue-derived EVs from high-fat diet (HFD)-fed mice, as well as in other obesity-related conditions. …”
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