Comparative Efficacy of Subcutaneous Versus Intravenous Interleukin 12/23 Inhibitors for the Remission of Moderate to Severe Crohn’s Disease: A Systematic Review and Meta-Analysis... by Nouran Alwisi, Rana Ismail, Hissa Al-Kuwari, Khalifa H. Al-Ansari, Mohammed A. Al-Matwi, Noor A. Aweer, Wejdan N. Al-Marri, Yousif Al-Kubaisi, Muneera Al-Mohannadi, Shahd Hamran, Suhail A. R. Doi, Habib H. Farooqui, Tawanda Chivese

“…For the maintenance of remission, only two studies had analyzable data, and they showed that subcutaneous interleukin 12/23 inhibitors were equal or better compared to intravenous administration. …”
Get full text

Oral health literacy and oral health status of a german adult population with migration background – findings from the MuMi Study by Berit Lieske, Christopher Kofahl, Katrin Borof, Kristin Spinler, Anna Poth, Demet Dingoyan, Thomas Beikler, Guido Heydecke, Ghazal Aarabi

“…Thus, future research should focus on tailored preventive measures for improving oral health literacy, thereby helping to strengthen equal opportunities in oral health in Germany.…”
Get full text

Comparison of myopia-related behaviors among Chinese school-aged children and associations with parental awareness of myopia control: a population-based, cross-sectional study by Chaoying Ye, Chaoying Ye, Chaoying Ye, Yujie Wang, Yujia Liu, Yujia Liu, Yujia Liu, Xingxue Zhu, Xingxue Zhu, Xingxue Zhu, Jianmin Shang, Jianmin Shang, Jianmin Shang, Xiaomei Qu, Xiaomei Qu, Xiaomei Qu

“…Samples were equally allocated to each subgroup of city tiers, children’s age groups, and children’s refractive statuses. …”
Get full text

Disparities in dolutegravir utilisation in children, adolescents and young adults (0–24 years) living with HIV. An analysis of the IeDEA Pediatric West African cohort by Valériane Leroy, Anandi Sheth, Julie Jesson, Jean Jacques Koffi, Antoine Jaquet, François Dabis, Didier Koumavi Ekouevi, Karen Malateste, Olivia Keiser, Lehila Bagnan, Simon Boni, Madeleine Amorissani Folquet, Mariam Sylla, Olivier Marcy, Raoul Moh, Gildas Boris Hedible, Sophie Desmonde, Joycelyn Dame, Agatha David, Madeleine Amorissani-Folquet, Sylvie N'Gbeche, Elom Takassi, François Tanoh Eboua, Kouadio Kouakou, Lehila Bagnan Tossa, Caroline Yonaba, Jocelyn Dame, Sylvie Marie N’Gbeche, Fatoumata Dicko Traore, Oliver Ezchechi, Rosemary Audu, Charlotte Bernard, Caroline Couturier, Marie Kerbie Plaisy, Elodie Rabourdin, Thierry Tiendrebeogo, Désiré Dahourou, Emile Sodinyessi, Jean-Claude Azani, Kadidja Diarra, Maika Bengali, Abdoulaye Cissé, Guy Gnepa, Eric Komena, Séverin Lenaud, Eulalie Kangah, Igho Ofotokun, Cecile Delille Lahiri, Noëlle Benzekri, Geoffrey Gottlieb

“…Maintained monitoring and support of treatment practices is required to better ensure universal and equal uptake.…”
Get full text

Hand Grip Strength Cut‐Off Points as a Discriminator of Sarcopenia and Sarcopenic Obesity: Results from the ELSA‐Brasil Cohort by Clarice Alves Santos, Helena Fraga Maia, Francisco José Gondim Pitanga, Maria da Conceição Chagas deAlmeida, Maria de Jesus Mendes daFonseca, Estela Mota Leão deAquino, Letícia de Oliveira Cardoso, Rosane Harter Griep, Sandhi Maria Barreto, Claudia Kimie Suemoto, Paulo Lotufo, Isabela Bensenor, Sheila Maria Alvim deMatos

“…Conclusions The results suggest that HGS is a good discriminator of sarcopenia and sarcopenic obesity, capable of achieving superior or equal performance to muscle mass biomarkers, especially in middle‐aged adults.…”
Get full text

[18F]FMISO PET in metastatic neuroendocrine tumours: a pilot study by David Chan, Alice Conner, Nick Pavlakis, Elizabeth Bailey, Alireza Aslani, Kathy Willowson, Connie Diakos, Elizabeth Bernard, Stephen Clarke, Alexander Engel, Paul Roach, Dale Bailey

“…The dynamic acquisition was analysed quantitatively using a graphical approach yielding parametric images of Influx Rate Constant and Volume of Distribution. [18F]FMISO uptake within the identified DONUT hole on the 2 hr delayed scan was qualitatively scored by two experienced nuclear medicine physicians as: 0 (no uptake), 1 (uptake less than normal liver), 2 (uptake equal to normal liver), or 3 (uptake greater than normal liver). …”
Get full text

Evaluation of Race-Neutral Glomerular Filtration Rate Estimating Equations in an Indian Population by Ashok Kumar Yadav, Jaskiran Kaur, Prabhjot Kaur, Kajal Kamboj, Yoshinari Yasuda, Masaru Horio, Arnab Pal, Nusrat Shafiq, Nancy Sahni, Harbir Singh Kohli, Seiichi Matsuo, Vivek Kumar, Vivekanand Jha

“…Results: A total of 412 subjects (55% with CKD), average age 47 ± 11 years with an equal distribution of males and females were enrolled. …”
Get full text

Biological Activity study of the <i>Melampyrum sylvaticum</i> Extract by E. E. Galishevskaya, E. N. Polyakova, T. V. Bombela, A. V. Agafontseva, A. G. Anisimova, O. A. Krotkova, T. A. Yagontseva, V. G. Luzhanin, E. R. Kurbatov

“…To investigate the in vivo acute toxicity, anticonvulsant and sedative activity of a dry alcohol extract from the aerial part of Melampyrum sylvaticum.Materials and methods. The extract was obtained by extracting substances from the aerial part of Melampyrum sylvaticum with 50 % ethanol, by the method of repercolation with an equal loading of raw materials, followed by evaporation to a dry residue. …”
Get full text

Combination of Essential Oils and Extracts Enriched with Tocopherols in Diet of Holstein Steers and Its Effect on Ruminal Fermentation, Antioxidant and Anti-Inflammatory Response,... by João Gustavo Weschenfelder Wandscheer, Natalia Turcatto, Guilherme Luiz Deolindo, Mateus Henrique Signor, Alexandro Fritzen, Marcelo Vedovatto, Camila Ten Kathen Jung, Gilberto Vilmar Kozloski, Ana Carolina Hadlich Xavier, Roger Wagner, Bianca Fagan Bissacotti, Priscila Marquezan Copetti, Aleksandro Schafer da Silva

“…Conclusions: The use of the phytogenic in steers’ diets has shown to be a viable candidate for replacing monensin, presenting equal or superior performance results with systemic modulating effects on oxidative stress, meat quality, and serum and biochemical parameters that contribute to more substantial health and efficiency.…”
Get full text

Normal tissue complication probability modeling for late rectal bleeding after conventional or hypofractionated radiotherapy for prostate cancer by Christian A.M. Jongen, Ben J.M. Heijmen, Wilco Schillemans, Andras Zolnay, Marnix G. Witte, Floris J. Pos, Ben Vanneste, Ludwig J. Dubois, David van Klaveren, Luca Incrocci, Wilma D. Heemsbergen

“…EUD (n = 0.1), D0.1cm3 and D2cm3 performed overall best in predicting G2 LRB; with α/β = 2 Gy equally good models were obtained. External validation is required to confirm our results.…”
Get full text

White matter hyperintensity burden and infarct volume predict functional outcomes in anterior choroidal artery stroke: a multimodal MRI study by Weiwei Gao, Weiwei Gao, Weiwei Gao, Mingyang Wang, Jianzhong Lin, Junyi Huang, Lijuan Cai, Lijuan Cai, Xingyu Chen, Xingyu Chen, Renjing Zhu, Renjing Zhu, Renjing Zhu

“…WMH burden was assessed using the Fazekas visual rating scale and an automated volumetric quantification method based on lesion prediction algorithms. …”
Get full text

Significance of Normal Lung Volume on Quantitative CT Imaging Analysis in Group 1 and Group 3 Pulmonary HypertensionTake-home Points by Tadasu Okaya, MD. PhD, Ayako Shigeta, MD. PhD, Nobuhiro Tanabe, MD. PhD, Koichiro Tatsumi, MD. PhD, Hajime Yokota, MD. PhD, Akira Nishiyama, MD. PhD, Akira Naito, MD. PhD, Ayumi Sekine, Toshihiko Sugiura, MD. PhD, Seiichiro Sakao, MD. PhD, Takuji Suzuki, MD. PhD

“…The optimal cutoff point of %NLV for predicting survival was examined using the receiver operating characteristic (ROC) curve. The Kaplan-Meier method and Cox proportional hazards regression were used to detect the association between %NLV and prognosis. …”
Get full text

Efficacy and safety of first-line or second-line selective laser trabeculoplasty for normal-tension glaucoma: a multicentre cohort study by Tomoko Naito, Kazuyuki Hirooka, Toru Nakazawa, Masaki Tanito, Shiro Mizoue, Katsuyoshi Suzuki, Keiji Yoshikawa, Itaru Kimura, Yasushi Ikuno, Takako Miki, Kazuhisa Sugiyama, Tairo Kimura, Akiko Narita, Tadashi Nakano, Tomoyuki Watanabe, Koji Nitta, Kae Sugihara, Maki Katai, Takuji Matsuda, Hiroaki Ozaki, Kaori Komatsu, Yoshiaki Saito, Takeshi Sagara, Aika Tsutsui, Akiko Ishida, Satoru Tsuda, Toyoaki Tsumura, Naoki Tojo, Naoto Tokuda, Kenji Nakamoto, Naka Shiratori, Mami Nanno, Naoya Nezu, Yoshitaka Tasaka, Shigeru Mori, Shigeki Yamabayashi, Kimihito Konno, Miyuki Domoto

“…Background/aims This study aimed to investigate and compare the efficacy and safety of first-line and second-line selective laser trabeculoplasty (SLT) in Japanese patients with normal-tension glaucoma (NTG).Methods 100 patients with NTG were enrolled in this study. …”
Get full text

Individual-level characteristics and geospatial factors associated with cervical cancer screening participation in Alberta, Canada: a population-based cross-sectional study by Jessica Law, Geneviève Jessiman-Perreault, Amanda Alberga Machado, Linan Xu, Bonnie Chiang, Huiming Yang, Lisa Allen Scott, Rizwan Shahid, Curtis Mabilangan, Alvin Li, Kamala Adhikari, Gary Teare

“…Geospatial analyses including heat maps were used to visualize variation in screening participation across the province. …”
Get full text

Monitoring and assessment of SARS-CoV-2 evolution by V. V. Miasoiedov, P. V. Nartov, K. V. Yurko, V. M. Lesovoy, V. A. Kapustnyk, A. V. Bondarenko, M. Ye. Cherniak, V. A. Yakushchenko, V. V. Kucheriavchenko, V. S. Maslova, O. V. Bondarenko

“…A real-time polymerase chain reaction (PCR) method was used for primary identification with the diagnostic kit “Biocore® SARS-CoV-2” (LLC “Biocor Technology Ltd.”, Ukraine) in accordance with the manufacturer’s instructions. …”
Get full text

Focal liver lesions: multiparametric microvasculature characterization via super-resolution ultrasound imaging by Qian-Qian Zeng, Shi-Zhe An, Chao-Nan Chen, Zhen Wang, Jia-Cheng Liu, Ming-Xi Wan, Yu-Jin Zong, Xiao-Hua Jian, Jie Yu, Ping Liang

“…Methods Patients with FLLs between June 2022 and February 2023 were prospectively screened. …”
Get full text

Combinations of polymorphisms in the regulatory regions of cytokine genes are associated with diabetic retinopathy in type 2 diabetic patients by V. I. Konenkov, A. V. Shevchenko, V. F. Prokof`ev, V. V. Klimontov, N. V. Tyan, V. V. Chernykh, D. V. Chernykh, A. V. Eremina, A. N. Trunov

“…The networks between genes and quartiles of glycated hemoglobin A1c (HbA1c) were visualized with Cytoscape.Results. We revealed 36 combinations of SNPs with different frequencies in the groups of patients with and without DR. …”
Get full text

The Swiss Endometriosis Database: a retrospective multicentre cohort study on pain levels and multimodal treatment needs of endometriosis patients by Sara Imboden, Selina Lang, Antonalla Martino, Peter Martin Fehr, Lea Duempelmann, Cloé Vaineau, Heike Willi, Nicolas Samartzis, Simone Kamm, Dimitri Sarlos, Stephanie Verta, Tina Rohrbach, Christian Polli, Alexandra Kochanowski, Michael Mueller

“…Data were collected by using questionnaires that were filled out by the patient and the physician at the first consultation, to evaluate parameters that included the main reason for consultation, visual analogue scale (VAS) scores for pain, clinical findings and therapy recommendations. …”
Get full text

Erector spinae plane block versus transversus abdominis plane block with rectus sheath block for postoperative analgesia in laparoscopic hepatectomy: a randomized clinical trial by Mengke Liu, Xuan Mo, Ruonan Zhan, Han Wang, Yangxi Zhao, Yi Zhang

“…Postoperative cumulative morphine consumption, the number of rescue analgesia, visual analog scale (VAS) scores at rest and during coughing, central venous pressure (CVP) values, Quality of Recovery Scale- 15 (QoR- 15) score, postoperative liver function, postoperative complications, duration of abdominal drain retention, and length of hospitalization were secondary outcomes. …”
Get full text

Am I attached? A patient-partnered approach to creating infographics about attachment to primary care in Ontario, Canada by Maggie MacNeil, Aya Tagami, Peter Sheffield, Vivian R. Ramsden, Joan Barker, Jennifer Boyle, Clare Cruickshank, Eliot Frymire, Richard H. Glazier, Anita Gombos Hill, Michael E. Green, Mary Huang, Marijke Jurriaans, Caron Leid, Melissa McCallum, Sarah Precious, Jo-Ann Stans, Julie Vizza, Murray Walz, Sue Wilkins, Rebecca Ganann

“…Our approach to engaging patients prevented both oversimplification and unnecessary complexity in a public-facing visual about attachment to primary care.…”
Get full text