Network pharmacology-based approach to research the effects and mechanisms of Salvia Miltiorrhiza injection against idiopathic pulmonary fibrosis by Liangyu Chen, Liangyu Chen, Haobo Lin, Haobo Lin, Haobo Lin, Linmang Qin, Linmang Qin, Linmang Qin, Guangfeng Zhang, Guangfeng Zhang, Guangfeng Zhang, Peisheng Chen, Zebo Jiang, Pan Xu, Donghui Huang, Xiao Zhang, Xiao Zhang

“…A protein–protein interaction (PPI) network of these targets was constructed using the STRING database and visualized with Cytoscape software, where the CytoHubba plug-in was utilized to determine core therapeutic targets. …”
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Validation of the traditional Chinese version of the Sinus and Nasal Quality of Life Survey (SN-5) for children by Wan-Yu Lai, David J. Kay, Chang-Ching Wei, Fen-Wei Huang, Kai-Li Liang, Hung-Rong Yen

“…We translated the SN-5 into traditional Chinese and evaluated validity and reliability. Methods: From December 2016 to December 2017, healthy volunteers and children with persistent sinonasal symptoms were enrolled. …”
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Mapping Antarctic Blue Ice Areas With Sentinel-2A/B Images and LightGBM Model by Xiaolong Teng, Jiahui Xu, Xiangbin Cui, Guitao Shi, Zhengyi Hu, Qingyu Gu, Bailang Yu, Jianping Wu, Yan Huang

“…While satellite remote sensing is effective in mapping BIAs, traditional methods rely on limited spectral bands and linear models with inherent limitations. …”
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Deciphering the role of Wnt/β-catenin and miR-214 in knee osteoarthritis: molecular and clinical insights by Waad A. Samman, Esraa M. Mosalam, Esraa M. Mosalam, Dalia S. Saif, Mahmoud S. Abdallah, Mahmoud S. Abdallah, Abdel-Aziz A. Zidan, Amany Said Sallam, Shimaa Abdelsattar, Fatma Omar Khalil, Amany E. Elashkar, Somia Mokabel Mohamed, Mohamed Al-Ghannam, Hend E. Abo Mansour, Hend E. Abo Mansour

“…Our study aims to investigate the implication of Wnt/ β-catenin pathway in development of KOA by detection of the downstream target genes and their crosstalk with miR-214 in patients with KOA and to correlate that with the clinical findings.MethodsSixty participants were involved in the study. …”
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Effects of herbal medicines (Eunkyosan/Yin qiao san and Samsoeum/Shen su yin) for treating the common cold: A randomized, placebo-controlled, multicenter clinical trial by Kwan-Il Kim, Minna Hong, Yang-Chun Park, Beom-Joon Lee, Kitae Kim, Byoung Kab Kang, Jun-Yong Choi

“…The secondary outcomes included visual analog scale (VAS) scores and the duration of symptoms was assessed throughout the trial. …”
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CHANGES IN CALPROTECTIN LEVEL, ITS RELATIONSHIP TO THE CLINICAL AND LABORATORY PARAMETERS OF DISEASE ACTIVITY AND SIGNIFICANCE FOR PREDICTING THE THERAPEUTIC RESPONSE IN RHEUMATOID... by A. O. Pchelintseva, A. P. Zhornyak, N. G. Ionichenok, E. Yu. Panasyuk, A. E. Ilyina, I. A. Andrianova, E. E. Gubar, E. S. Tsvetkova, M. V. Cherkasova, E. N. Aleksandrova, L. N. Denisov, E. L. Nasonov

“…To assess RA activity, tender and swollen joint count, pain, patient’s and physician’s assessment of global disease activity on 100-mm visual analogue scale and DAS28 were used. Functional status was evaluated by HAQ and RAPID3. …”
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EULAR standardised training model for ultrasound-guided, minimally invasive synovial tissue biopsy procedures in large and small joints by Annamaria Iagnocco, Andrew Filer, Gabriel Herrero-Beaumont, Peter Balint, Ingrid Moller, Esperanza Naredo, Lene Terslev, Alessandra Bruns, Aurélie Najm, Ana Rodriguez, Raquel Largo, Stefano Alivernini, Jesús Garrido, Maria Antonietta D’Agostino, Jacqueline Uson, Juhani Koski, Maribel Miguel, Carlos Guillén-Astete, David A. Bong, George A.W. Bruyn, Carlos Acebes

“…Objectives To develop an EULAR training model for education in synovial tissue biopsy (STB) under ultrasound guidance (UG) following a stepwise approach: (1) development of educational material on UGSTB in large and small joints; (2) assessment of the validity, reliability and feasibility of the UGSTB educational procedure on cadaveric specimens; (3) validation of this procedure in live patients.Methods Using a nominal group (NG) and a DELPHI consensus methodology, educational audio-visual (AV) material and minimal requirements for education in UGSTB were developed by an expert panel. …”
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Cognition and behavior in adults with neurofibromatosis type 1 by Anja Bos-Roubos, Anja Bos-Roubos, Anja Bos-Roubos, Hanneke van Leeuwen, Hanneke van Leeuwen, Hanneke van Leeuwen, Ellen Wingbermühle, Ellen Wingbermühle, Ellen Wingbermühle, Ellen Wingbermühle, Louisa van den Bosch, Lindsey Ossewaarde, Walter Taal, Walter Taal, Laura de Graaff, Laura de Graaff, Laura de Graaff, Jos Egger, Jos Egger, Jos Egger, Jos Egger, Jos Egger

“…Cognition and behavior was tested against population means constructed by bootstrapping.ResultsPerformance on the cognitive measures oral reading speed, visuospatial copying, visuospatial immediate recall, visual learning/imprinting, and visual memory immediate recall in the NF1 group were lower than normative means. …”
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Using Human-Centered Design to Bridge Zero-Dose Vaccine Gap: A Case Study of Ilala District in Tanzania by Simon Martin Nzilibili, Hellen Maziku, Awet Araya, Ruthbetha Kateule, Millenium Anthony Malamla, Suna Salum, Furaha Kyesi, Lotalis Gadau, Tumaini Menson Haonga, Florian Tinuga, Rashid Mfaume, Zaitun Hamza, Georgina Joachim, Alice Geofrey Mwiru, Alex Benson, Oscar Kapela, Ona Machangu, Norman Jonas, Ntuli Kapologwe

“…As a result, 67,145 houses, equal to 104%, were reached, surpassing the initial target of 64,800 houses, and 131,088 families, equal to 83% of the targeted 156,995 households, were sensitized through a home-to-home campaign approach. …”
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Improvement in long-term survival with mesenchymal stem cell transplantation in systemic sclerosis patients: a propensity score-matched cohort study by Wenyi Yuan, Mian Liu, Dapeng Yang, Yirui Shi, Zhikang Wang, Xuan Cao, Jun Liang, Linyu Geng, Huayong Zhang, Xuebing Feng, Ziyi Jin, Dandan Wang, Lingyun Sun

“…While several studies have investigated the therapeutic potential of mesenchymal stem cell transplantation (MSCT), the clarity of its long-term outcomes for SSc patients is still lacking. Methods Data on MSCT were extracted from the medical records of inpatients at Nanjing Drum Tower Hospital between January 2013 and December 2022. …”
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Proportional representation and incidence rate of repeat visits in ethnic minorities compared to native Dutch people under the age of 25 years in the Netherlands by Y.J. Evers, A. Verhaegh, A. Ibrahim, C. Peters, N.H.T.M. Dukers-Muijrers, R. Reijs, C.J.P.A. Hoebe

“…In this study, we aimed to determine the proportional representation of first- and second generation EMs under 25 years at Dutch Sexual Health Centers (SHCs) compared to native Dutch citizens. Methods: In this retrospective cohort study, coded health records data of 270,927 persons in the age group of 15 till 24 years visiting SHCs between 2016 and 2021 were included. …”
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Effect of traditional Chinese medicine combined with conventional Western medicine for patients with severe/very severe chronic obstructive pulmonary disease: a multi-center, rando... by Jiansheng Li, Yang Xie, Minghang Wang, Suyun Li, Xuefeng Yu, Nianzhi Zhang, Zhengang Zhu, Wei Zhang, Jihong Feng, Zikai Sun, Lin Lin, Zhijia Sun, Hailong Zhang, Xueqing Yu

“…This study aimed to evaluate the clinical efficacy of comprehensive therapy based on TCM patterns for patients with stable, severe to very severe COPD. Methods A multicenter, randomised, double-blind, placebo-controlled trial was conducted. …”
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Diagnostic work-up of lipomatous tumors: a decision-making analysis among European sarcoma centers by Ali Naimi, Paul Martin Putora, Christian Rothermundt, Antonia Digklia, Jose Manuel Asencio, Sylvie Bonvalot, Florian Bösch, Anant Desai, Amer James Durrani, Haim Gutman, Daphne Hompes, Jens Jakob, Wolfram Trudo Knoefel, Elisabetta Pennacchioli, Piotr Rutkowski, Winan J. van Houdt, Barbara L. van Leeuwen, Stephan Waelti, Tim Steffen Fischer, Stefan Markart, Simon Wildermuth, Tobias Johannes Dietrich

“…In these settings, CNB and follow-up were almost equally recommended. For lipomatous tumors smaller than 3 cm, without growth or symptoms, no localization in the trunk, and homogeneous imaging features, a consensus rate of 71% was achieved for follow-up. …”
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Ensemble Computational Intelligent for Insomnia Sleep Stage Detection via the Sleep ECG Signal by Pragati Tripathi, M. A. Ansari, Tapan Kumar Gandhi, Rajat Mehrotra, Md Belal Bin Heyat, Faijan Akhtar, Chiagoziem C. Ukwuoma, Abdullah Y. Muaad, Yasser M. Kadah, Mugahed A. Al-Antari, Jian Ping Li

“…For the sleep stage-based classification scenario, the detection evaluation results are recorded equally with 96.0% for ceiling level accuracy, sensitivity, and specificity. …”
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Heterogeneous treatment effects of stress ulcer prophylaxis among ICU patients at risk for gastrointestinal bleeding by Yongpeng Xie, Yao Yan, Qixiang Hong, Hui Zheng, Lijuan Cao, Xiaoming Li, Songqiao Liu, Hui Chen

“…Understanding HTE is crucial for tailoring SUP to individual treatment. Methods This cohort study included patients admitted to intensive care unit (ICU) with at least one risk factor for clinically important gastrointestinal bleeding (GIB). …”
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Safety and efficacy of amnion-derived mesenchymal stem cells (AM01) in patients with steroid-refractory acute graft-versus-host disease after allogeneic haematopoietic stem cell tr... by Hiroki Nishikawa, Shunsuke Ohnishi, Hiroshi Hayashi, Rika Okamoto, Kenichi Yamahara, Toshiyuki Isoe, Norihiro Sato, Akiko Hamada, Toshihiro Soma, Masaya Okada, Satoshi Yoshihara, Kyoko Yoshihara, Kazuhiro Ikegame, Hiroya Tamaki, Katsuji Kaida, Takayuki Inoue, Yuko Ohsugi, Hiroaki Iijima, Daigo Hashimoto, Takanori Teshima, Hiroyasu Ogawa, Yoshihiro Fujimori

“…Our non-clinical studies confirmed that human amnion-derived MSCs had immunomodulatory activity equal to or higher than that of human bone marrow MSCs. …”
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Comparison of the TNM9th and 8th editions for localized and locally advanced anal squamous cell carcinoma treated nonsurgically and proposal of a new stage grouping system by Aihong Zheng, Yiwen Wang, Shuang Li, Yingjie Wang, Hong'en Xu, Jieni Ding, Bingchen Chen, Tao Song, Lei Lai

“…Survival comparisons between the T and N stages and the different staging systems were performed using the Kaplan–Meier method and log‐rank test, followed by correlation analysis and variable importance analysis (VIA). …”
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Long-Term Safety and Efficacy of Lenabasum, a Cannabinoid Receptor Type 2 Agonist, in Patients with Dermatomyositis with Refractory Skin Disease: Follow-Up Data from a 3-Year Open-... by Caroline J. Stone, Geeta Ahuja, Lais Lopes Almeida Gomes, Joy Poroye, Daniella Forman Faden, Lillian Xie, Rui Feng, Barbara White, Victoria P. Werth

“…Key aims include evaluating the drug’s long-term effectiveness and assessing disease manifestation recurrence. Methods: The phase 2 lenabasum trial enrolled patients with treatment-resistant, skin-predominant DM. …”
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Monitoring Anthropogenically Disturbed Parcels with Soil Erosion Dynamics Change Based on an Improved SegFormer by Zhenqiang Li, Jialin Li, Jie Li, Zhangxuan Li, Kuncheng Jiang, Yuyang Ma, Chuli Hu

“…Currently, traditional methods for change detection, such as field surveys and visual interpretation, suffer from time inefficiencies, complexity, and high resource consumption. …”
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Key motor and non-motor features in early dementia with Lewy bodies by Anna Planas-Ballvé, Anna Planas-Ballvé, José Rios, Lourdes Ispierto, Mireia Gea, Laia Grau, Marta Jiménez, Cynthia Cáceres, Sílvia Martínez, Katrin Beyer, Ramiro Álvarez, Pau Pastor, Dolores Vilas, Dolores Vilas

“…ObjectiveThe objective of our study was to characterize early-stage dementia with Lewy bodies (DLB) focusing on motor and non-motor symptoms.MethodsThis cross-sectional study prospectively included newly diagnosed DLB patients within 3 years of cognitive symptom onset. …”
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