Effect of perioperative ONS combined with intestinal microecology in patients with colorectal cancer: a randomized clinical trial by Xuanjun Liu, Weixu Mao, Guowei Zhao, Juan Liao, Qigang Li, Gan He

“…PurposeTo investigate the combined effects of oral nutritional supplement (ONS) and intestinal microecology on postoperative nutrition status, inflammatory response and intestinal flora regulation colorectal cancer (CRC) patients.MethodsThis prospective single-center randomized controlled trial (RCT) was conducted at Chongqing Yongchuan Hospital between December 2023 and December 2024. …”
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Enhancing adoptive cancer immunotherapy with Vγ2Vδ2 T cells through pulse zoledronate stimulation by Hong Wang, Mohanad H. Nada, Grefachew Workalemahu, Yoshimasa Tanaka, Craig T. Morita

“…Additionally, IL-15 increases the anti-tumor activity of murine αβ T cells in mice but its effect on the in vivo anti-tumor activity of human Vγ2Vδ2 cells has not been assessed.Methods Human Vγ2Vδ2 T cells were expanded by pulse or continuous zoledronate stimulation with IL-2 or IL-15. …”
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m6A-Methylated NUTM2B-AS1 Promotes Hepatocellular Carcinoma Stemness Feature via Epigenetically Activating BMPR1A Transcription by Li W, Zeng M, Ning Y, Lu R, Wei Y, Xu Z, Wei H, Pu J

“…However, whether m6A has oncofetal characteristics remains unknown.Methods: Gene expression in HCC tissues and cells was detected using qPCR. …”
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Comparative Genomic Analysis of Tigecycline Resistance Development in Clinical Acinetobacter baumannii Isolates by Li X, Liu J, Zhang X, Li J, Xuan L, Yuan S, Li J, Sun Y, Du X

“…The goal is to provide clinical insights into the development of tigecycline resistance in A. baumannii, with a focus on multidrug-resistant strains commonly associated with hospital-acquired infections.Methods: We conducted dynamic tracking of multidrug-resistant Acinetobacter baumannii (MDR-AB) infections in three patients to monitor changes in tigecycline sensitivity during antimicrobial therapy. …”
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Acute tonsillitis and pediatric functional gastrointestinal disorders: the first result of a possible association analysis by E. R. Meskina, L. A. Galkina, T. V. Stashko

“…The aim is to discover a possible relationship between acute exudative tonsillitis and FDDS in children in the context of clinical and medico-social assessment. Materials and Methods: An observational cross-sectional study was performed using the continuous sampling method. …”
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Effect of Uncertainty-Aware AI Models on Pharmacists’ Reaction Time and Decision-Making in a Web-Based Mock Medication Verification Task: Randomized Controlled Trial by Corey Lester, Brigid Rowell, Yifan Zheng, Zoe Co, Vincent Marshall, Jin Yong Kim, Qiyuan Chen, Raed Kontar, X Jessie Yang

“…ResultsA total of 30 participants provided complete datasets. An equal number of participants were in each AI condition. …”
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Severe soft tissue injuries in multiple trauma patients—a challenge we can meet? A matched-pair analysis from the TraumaRegister DGU® by Nora Kirsten, Georg Maximilian Franke, Rolf Lefering, Tim Klüter, Matthias Weuster, Michael Müller, Sebastian Lippross, Andreas Seekamp, TraumaRegister DGU®, Stefanie Fitschen-Oestern

“…Concomitant soft tissue injuries represent a particular challenge, as they can lead to complications at any time of trauma care, hold a high risk of infection and often require multiple surgical interventions and interdisciplinary collaboration.MethodsThis retrospective, multicentric study used the TraumaRegister DGU® to examine the effect of open fractures and severe soft tissue injuries on outcome of multiple trauma patients. …”
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Quantitative Assessment of Psychological Stress Changes Before and After Ureteral Stent Placement: A Prospective Observational Study by Fu Y, Liang P, Gao X, Mo Z, Ruan Y, Pan J

“…This study aimed to quantitatively evaluate psychological stress changes before and after ureteral stent placement in order to better understand patients’ psychological needs during this common urological procedure.Methods: This prospective observational study with paired before-after measurements was conducted at Yangjiang Hospital of Traditional Chinese Medicine between November 2024 and March 2025. …”
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Study on the Regulated Cell Death of Hypertrophic H9c2 Cells Induced by Au:Ag Nanoparticles by Galindo-Padrón AG, Lorenzo-Anota HY, Rueda-Munguía M, García-Carrasco A, Gaitán López M, Vázquez-Garza E, Campos-González E, Lozano O, Cholula-Díaz JL

“…The main objective of this work is to explore the susceptibility of cells due to exposure to Au:Ag NPs in conditions representing cardiometabolic diseases.Methods: Au:Ag NPs were synthesized in different molar ratios (Au:Ag, 100:0, 75:25, 50:50, 25:75, 0:100) using starch as a capping and reducing agent. …”
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Therapeutic Potential of PDA@CeO2 in Suppressing Hepatic Stellate Cell Activation and Preventing Liver Fibrosis by Li HM, Zhang JY, Wang XQ, Ye LT, Ren B, Leng YH, Zhang JX, Yang Y, Jiang Q, Feng LL, Li Y, Yu JH

“…This study tests the hepatoprotective effects of PDA@CeO2 nanoparticles in scavenging ROS, inhibiting HSC activation, and delaying fibrosis, using 2D-SWE to assess treatment efficacy.Methods: In vitro, flow cytometry evaluated ROS levels in HSCs, scratch assays assessed migration, and α-SMA expression confirmed activation. …”
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Systemic Immune-Inflammation Index (SII) and Neutrophil-to-Lymphocyte Ratio (NLR): A Strong Predictor of Disease Severity in Large-Artery Atherosclerosis (LAA) Stroke Patients by Liu K, Yang L, Liu Y, Zhang Y, Zhu J, Zhang H, He Z

“…This study aimed to verify the predictive value of the clinical parameters such as systemic immune-inflammation index (SII) and neutrophil-to-lymphocyte ratio (NLR) for the severity in Large Artery Atherosclerosis (LAA) stroke patients.Methods: The SII is defined as platelet × (neutrophil count/lymphocyte count), the NLR is defined as neutrophil count/lymphocyte count. …”
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Chaihuang Qingfu Pills Protect Against Acute Pancreatitis—Associated Acute Lung Injury Through MMP9-NLRP3-Pyroptosis Pathway by Xiao W, Shi H, Tian Y, Chen F, Xie Y, Han X, Zhang X, Cao Y, Liu W, Zhu Y, Liu Y, Jiang Y

“…However, its role in SAP-ALI and the underlying mechanisms remain unclear.Methods: 92 AP patients were enrolled to observe the protective effect of CHQF on AP-ALI. …”
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Robot-assisted laparoscopic ureteropelvic junction plasty in children using the da Vinci Xi robotic system: a Russian first experience by V. V. Sizonov, A. G. Makarov, S. M. Pakus, D. G. Kvaratskhelia, E. V. Orlova, S. G. Piskunova, M. I. Kogan

“…The patient cohort consisted of an equal distribution of 7 boys (50%) and 7 girls (50%). …”
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Liver Function Abnormalities in Patients with Chlamydia psittaci Pneumonia: A Multicenter Retrospective Study by Fang C, Xu L, Lu J, Li Y, Zhao Z

“…In this study, we aimed to elucidate the characteristics of liver function changes and the factors influencing liver injury in patients with Chlamydia psittaci pneumonia, providing a reference for clinical treatment.Methods: The clinical data of patients with Chlamydia psittaci pneumonia admitted to three tertiary Grade A hospitals in Guangdong Province, China, from January 2020 to February 2025 were retrospectively collected. …”
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Current Strategies to Reducing Interval Breast Cancers: A Systematic Review by Goh RSJ, Chong B, Yeo S, Neo SY, Ng QX, Goh SSN

“…We found that using digital breast tomosynthesis (a 3D imaging method) generally reduced missed cancers compared to traditional mammograms, especially in women with dense breasts. …”
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LncRNA PTS-1 Protects Against Osteoarthritis Through the miR-8085/E2F2 Axis by Ma C, Chen Q, Wei YF, Chen SW, Liu H, Xin F, Ren YX

“…This study focuses on lncRNA PTS-1, a novel lncRNA, to explore its function and regulatory mechanisms in OA progression.Methods: The expression profile of lncRNAs was assessed using RNA sequencing and qRT-PCR. …”
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Isokinetic peak torque and flexibility changes of the hamstring muscles after eccentric training: Trained versus untrained subjects by Amr Almaz Abdel-aziem, Elsadat Saad Soliman, Osama Ragaa Abdelraouf

“…Objective: The aim of this study was to examine the effect of eccentric isotonic training on hamstring flexibility and eccentric and concentric isokinetic peak torque in trained and untrained subjects. Methods: Sixty healthy subjects (mean age: 21.66 ± 2.64) were divided into three equal groups, each with 20 voluntary participants. …”
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In vitro Activity of Eravacycline and Risk Factors for Carbapenem-Resistant Acinetobacter Baumannii Infections in Patients with Respiratory Diseases: A Retrospective Cohort Study by Guan J, Wang Z, Dong Y, Wang J, Ren Y, Lu Z, Hu S, Duan X

“…In contrast, Eravacycline (ERV), a novel fluorocycline, exhibits potent activity against multidrug-resistant Gram-negative pathogens and may help mitigate these limitations.Patients and Methods: A retrospective analysis was conducted on 1071 CRAB isolates obtained from 524 respiratory patients at Shaanxi Provincial People’s Hospital in 2024. …”
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The Impact of Non-Thyroidal Illness Syndromes on The Prognosis and Immune Profile in Severe Fever with Thrombocytopenia Syndrome Patients by Wu H, Mu Y, Liu Y, Zhang R, Xu Y, Zhang Y, Zhao C, Zhang W, Lin L, Chen Z

“…This study aims to evaluate the impact of NTIS on the prognosis of SFTS patients and to explore the relationship between thyroid hormones (THs) and immune cell profiles.Methods: Adult patients admitted to Yantai Qishan Hospital for SFTS from January 2023 to December 2023 with no prior history of thyroid disease were retrospectively recruited. …”
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Unveiling Key Biomarkers and Mechanisms in Septic Cardiomyopathy: A Comprehensive Transcriptome Analysis by Zhao D, Zhuang J, Wang L, Wu L, Xu W, Zhao L, Hong J, Jin W, Miao C

“…This study aimed to identify hub biomarkers in SCM and explore their potential mechanisms.Methods: We utilized the GSE53007 and GSE207363 datasets for transcriptome analysis of normal and SCM mice. …”
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