Neuroprotection effect of bovine umbilical mesenchymal stem cell-conditioned medium on the rat model of Alzheimer's disease mediated by upregulation of BDNF and NGF and downre... by Hevi Wihadmadyatami, Muhammad Ali Zulfikar, Herawati Herawati, Srikanth Karnati, Golda Rani Saragih, Dinda Aliffia, Dyah A.O.A. Pratama, Nurrahmi Handayani, Ulayatul Kustiati, Dewi Ratih Tirtosari, Yudy Tjahjono

“…Interactions between the main substances of BUMSC-CM and beta-amyloid protein were visualized using in silico molecular docking. Results: Our result demonstrated that BUMSC-CM with the dosage of 0,5 ml/kg BW significantly increased BDNF concentration. …”
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Integrating Brain-Computer Interface Systems into Occupational Therapy for Enhanced Independence of Stroke Patients: An Observational Study by Erika Endzelytė, Daiva Petruševičienė, Raimondas Kubilius, Sigitas Mingaila, Jolita Rapolienė, Inesa Rimdeikienė

“…We hypothesized that integrating BCI into occupational therapy would result in measurable improvements in hand strength, dexterity, independence in daily activities, and cognitive function compared to baseline. <i>Materials and Methods</i>: An observational study was conducted on 56 patients with subacute stroke. …”
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Global insights into the genome dynamics of Clostridioides difficile associated with antimicrobial resistance, virulence, and genomic adaptations among clonal lineages by Mohammad Sholeh, Mohammad Sholeh, Masoumeh Beig, Masoumeh Beig, Ebrahim Kouhsari, Mahdi Rohani, Mohammad Katouli, Farzad Badmasti

“…Statistical analyses and visualizations were performed in R.ResultsAmong 366 identified STs, ST1 (1,326 isolates), ST2 (1,141), ST11 (893), and ST42 (763) were predominant. …”
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Effects of single subanesthetic dose of oxycodone on pain and Th1/Th2 balance in patients after radical mastectomy by QU Na，ZHAO Xiaohong，NI Qiang

“…Both groups received remifentanil for maintenance during surgery. Postoperative visual analog scale（VAS）scores，Th1 and Th2 levels were recorded at 1，6，12，24，and 48 hours post-surgery. …”
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Effects of PRP injection combined with intersecting femoral head decompression versus combined with multiple core decompression in the treatment of avascular necrosis of femoral he... by Lei Sun, Ziyao Xu, Zhongyuan Zhang, Jinwei Zhao, Mengshuai Sun, Guangling Gao, Fang Gao, Hongjiang Jiang, Changjun Ju

“…Postoperative functional outcomes were assessed using the Harris Hip Score (HHS) and Visual Analogue Scale (VAS), while radiographic progression was evaluated through standardized X-ray and computed tomography (CT) imaging protocols. …”
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Qualitative and quantitative ultrasound parameters of carotid atherosclerotic plaques in patients with moderate cardiovascular risk according to the SCORE scale: 7-year prospective... by O. A. Pogorelova, M. I. Tripoten, I. S. Melnikov, L. Sh. Khamchieva, B. M. Tamaeva, S. G. Kozlov, T. V. Balakhonova

“…Plaque number, maximum plaque height, total plaque height, total CA stenosis, visual plaque morphology, gray-scale median (GSM), and intima- media thickness of the right and left common CAs were assessed. …”
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Comparison of Milligan-Morgan Haemorrhoidectomy versus Laser Haemorrhoidoplasty in Patients with Grade II and III Haemorrhoids: A Prospective Observational Study by Asfar Ahamed Nawabjan, Sathish Rajkumar, Chudar Arumugam, Mohamed Marzook, Jasmine Sharmila, Lalith Kumar

“…The laser group had significantly lower postoperative pain {Visual Analogue Scale (VAS) 4.60±1.14 vs. 9.15±0.67 on Day 1, p<0.001}, shorter operative time (19.85 min vs. 54.75 min), reduced intraoperative blood loss (7±2.51 mL vs. 23±5.23 mL, p<0.001), and shorter hospital stay (1.1 vs. 1.85 days, p<0.001). …”
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Anatomical hemorrhoidectomy and semi-shutting suture combined with mucosal ligation for mixed hemorrhoids by Yuan Ke, Lei Yinfu, Chen Lina, Yu Lelai, Liu Huan, Shen Qingbo, Huang Qi, Pei Xi

“…The followings were compared between the two groups: effectiveness, surgical parameters, postoperative pain visual analog scale (VAS) score, postoperative complications, recurrence, and patients’satisfaction. …”
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Safety and efficacy of robot-assisted percutaneous kyphoplasty under local anesthesia in a day-surgery setting for osteoporotic vertebral compression fractures by Yaming Wu, Yang Yuan, Yi Yin, Yaqin Gong, Yaowei Ye, Li Wu, Lizhen Qian

“…This retrospective study evaluates the safety and efficacy of robot-assisted percutaneous kyphoplasty (PKP) performed under local anesthesia within a day-surgery framework.MethodsClinical data from 127 patients with OVCFs who underwent robot-assisted PKP under local anesthesia in a day-surgery setting at the First People's Hospital of Kunshan between May 2022 and April 2024 were retrospectively analyzed. …”
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Knowledge of telemedicine and its associated factors among health professional in Ethiopia: A systematic review and meta-analysis. by Adamu Ambachew Shibabaw, Alex Ayenew Chereka, Agmasie Damtew Walle, Addisalem Workie Demsash, Geleta Nenko Dube, Abiy Tasew Dubale, Sisay Yitayh Kassie, Gemeda Wakgari Kitil, Mesafint Zewold Jember, Chernet Desalegn Gebeyehu, Aster Temesgen Ariger, Eshetie Andargie Dires

“…The funnel plot was visually inspected, and Egger's regression test was run to check for publication bias. …”
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The Opportunity of Using Diode Laser with the Length of 1940 nm in the Treatment of Hemorrhoids by S. A. Frolov, A. M. Kuzminov, D. V. Vyshegorodtsev, O. A. Mainovskaya, Yu. L. Trubacheva, O. Yu. Fomenko, V. Yu. Korolik, I. S. Bogormistrov, I. A. Mukhin, A. M. Battalova, E. M. Bogdanova

“…A new treatment method based on the use of a diode laser with a wavelength of 1940 nm was applied to all patients. …”
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Noninferiority of 0.25% versus 0.375% Ropivacaine in Popliteal Sciatic and Saphenous Nerve Blocks for Analgesia After Foot and Ankle Surgery: A Randomized Self-Paired Noninferiorit... by Wu L, Xi C, Lei G, Li H, Yin Y, Wan M, Wu H, Wang Y, Hu C, Wang G

“…Hence, we hypothesized that the analgesic effect of 0.25% ropivacaine would be noninferior to that of 0.375% ropivacaine at the same volume and would reduce the degree of weakness.Patients and Methods: In this randomized, double-blind, self-paired, noninferiority trial, 31 patients who were scheduled for similar, elective, bilateral foot and ankle surgeries under general anesthesia combined with popliteal sciatic and saphenous nerve blocks were enrolled. …”
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Cognitive Disorders In Acquired Sensorineural Hearing Loss, At The Ent Department Of The &ldquo;Village Bondeko&rdquo; Center, In Kinshasa by Masamba GR, Sokolo Gedikondele J, Longo-Mbenza B, Nganga Nkanga MS, Matanda Nzanza R, Matonda-ma-Nzuzi T, Ikanga J, Nge Okwe A, Lema Mabwaka G, Mawalala Malengele H, Nangi Mampuya C, Lumbu Malundama D

“…Thus, the objective of the present study was to investigate the relationship between sensorineural hearing loss and cognitive disorders in a correlational approach.Methods: This is a cross-sectional and analytical study conducted in the ENT department of the Center for the Disabled (visual, auditory, and mental) “Village Bondeko”, from June to September 2023, involving 150 adults (≥ 20 years) with acquired sensorineural hearing loss; without a history of neuropsychic disorders. …”
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Assessment of publication time in Campbell Systematic Reviews: A cross‐sectional survey by Bei Pan, Long Ge, Xiaoman Wang, Ning Ma, Zhipeng Wei, Lai Honghao, Liangying Hou, Kehu Yang

“…Non‐normal distributed data were reported as medians, interquartile range, and range, and normal distributed data will be reported as mean ± standard deviation. And we also visualized the overall publication time and the distribution of data. …”
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Therapeutic Effect of Core Stability Training Combined with Extracorporeal Shock Wave on Lumbar Disc Herniation by Shuo LI, Lishuang LIU, Jinna ZHOU, Qiaoyun XIANG, Tingting LUAN, Wenwen WANG

“…The Combined group was given core stability training and extracorporeal shock wave therapy, and the method was the same as above. The pain degree was evaluated by visual analogue score (VAS) before treatment, 3 months of treatment and 6 months after treatment. …”
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Analysis of clinical knowledge, absenteeism and availability of resources for maternal and child health: a cross-sectional quality of care study in 10 African countries by Laura Di Giorgio, David K Evans, Magnus Lindelow, Son Nam Nguyen, Jakob Svensson, Waly Wane, Anna Welander Tärneberg

“…Objective Assess the quality of healthcare across African countries based on health providers’ clinical knowledge, their clinic attendance and drug availability, with a focus on seven conditions accounting for a large share of child and maternal mortality in sub-Saharan Africa: malaria, tuberculosis, diarrhoea, pneumonia, diabetes, neonatal asphyxia and postpartum haemorrhage.Methods With nationally representative, cross-sectional data from ten countries in sub-Saharan Africa, collected using clinical vignettes (to assess provider knowledge), unannounced visits (to assess provider absenteeism) and visual inspections of facilities (to assess availability of drugs and equipment), we assess whether health providers are available and have sufficient knowledge and means to diagnose and treat patients suffering from common conditions amenable to primary healthcare. …”
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Effectiveness of telerehabilitation in non-operatively managed shoulder conditions: a systematic review and meta-analysis by Ting-wan Lin, Yang Yang, Hai-yan Hong, Xiao-bo Zhou, Tao-Hsin Tung, Bin-bin Zheng, Jian-min Zhang

“…However, its overall efficacy remains uncertain due to inconsistent findings in prior studies. Methods This systematic review and meta-analysis assessed the effectiveness of telerehabilitation for non-operatively managed shoulder conditions, concentrating on randomized controlled trials (RCTs). …”
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Resting-state functional magnetic resonance imaging findings in patients with acoustic neuroma and tinnitus by ZHAN Xiaolin, REN Yi, LI Yongpeng, HUANG Qiao, YIN Shihua

“…Conclusion This study reveals the changes in the brain regions associated with tinnitus in acoustic neuroma involving multiple networks of the central nervous system, including the auditory network, visual network, default mode network and dorsal attention network. …”
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U-shaped association between serum chloride and hypertension risk with nadir around 103 mmol/L: insights from regression and interpretable machine learning (XGBoost/SHAP) using NHA... by Shancheng He, Xuemei Zhong, Guangming Chen, Long Li

“…This research attempted to explicate the link between serum levels of chloride and the risk of hypertension occurrence, as well as to identify the threshold level at which the risk undergoes changes across the general population and various demographic segments.MethodsEmploying materials from the to 2017–2018 National Health and Nutrition Examination Survey (NHANES; n = 4,591), we employed multivariate regression analysis to gauge the connection between adult serum chloride concentrations and the risk of hypertension occurring. …”
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Investigation of the antioxidant status and the number of double-stranded DNA breaks in models of brain tumor lesion by metastases of non-small cell lung cancer in vivo by E. V. Zaikina, I. A. Alliluev, Yu. N. Lazutin, Yu. V. Przhedetskiy, Yu. S. Shatova, M. A. Engibaryan, E. F. Komarova, D. A. Kharagezov, A. V. Galina, A. A. Kiblitskaya, M. V. Mindar, L. Z. Kurbanova

“…Growth rates were controlled and intracranial xenografts were visualized using a high-resolution micro-CT system. …”
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